PubRank

Gérard Waeber

Author PubWeight™ 238.50‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Biological, clinical and population relevance of 95 loci for blood lipids. Nature 2010 28.21
2 Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. Nat Genet 2010 23.08
3 New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. Nat Genet 2010 17.89
4 Meta-analysis and imputation refines the association of 15q25 with smoking quantity. Nat Genet 2010 8.55
5 Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge. Nat Genet 2010 6.66
6 LDL-cholesterol concentrations: a genome-wide association study. Lancet 2008 6.44
7 The CoLaus study: a population-based study to investigate the epidemiology and genetic determinants of cardiovascular risk factors and metabolic syndrome. BMC Cardiovasc Disord 2008 5.33
8 Meta-analysis of 28,141 individuals identifies common variants within five new loci that influence uric acid concentrations. PLoS Genet 2009 4.97
9 The Population Reference Sample, POPRES: a resource for population, disease, and pharmacological genetics research. Am J Hum Genet 2008 4.79
10 GWAS of 126,559 individuals identifies genetic variants associated with educational attainment. Science 2013 4.71
11 Genetic variants influencing circulating lipid levels and risk of coronary artery disease. Arterioscler Thromb Vasc Biol 2010 4.08
12 Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure. Nat Genet 2011 3.40
13 Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture. Nat Genet 2013 3.25
14 Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals. PLoS Genet 2012 3.21
15 Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma. Nat Genet 2011 3.18
16 Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile. Nat Genet 2011 2.73
17 Mirror extreme BMI phenotypes associated with gene dosage at the chromosome 16p11.2 locus. Nature 2011 2.59
18 Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways. Nat Genet 2012 2.12
19 Genome-wide linkage and association analyses to identify genes influencing adiponectin levels: the GEMS Study. Obesity (Silver Spring) 2009 2.07
20 Scores to predict major bleeding risk during oral anticoagulation therapy: a prospective validation study. Am J Med 2012 1.81
21 Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders. Nat Genet 2013 1.72
22 A genome-wide association search for type 2 diabetes genes in African Americans. PLoS One 2012 1.72
23 A genome-wide association study of early menopause and the combined impact of identified variants. Hum Mol Genet 2013 1.50
24 Eligibility to treatment and economic effect of the implementation of the new U.S. or European Society of Hypertension/European Society of Cardiology hypertension guidelines. J Hypertens 2015 1.40
25 Genetic and phenotypic architecture of metabolic syndrome-associated components in dyslipidemic and normolipidemic subjects: the GEMS Study. Atherosclerosis 2007 1.36
26 Relation between atherogenic dyslipidemia and the Adult Treatment Program-III definition of metabolic syndrome (Genetic Epidemiology of Metabolic Syndrome Project). Am J Cardiol 2005 1.32
27 Dose-dependent positive association between cigarette smoking, abdominal obesity and body fat: cross-sectional data from a population-based survey. BMC Public Health 2011 1.32
28 The PsyCoLaus study: methodology and characteristics of the sample of a population-based survey on psychiatric disorders and their association with genetic and cardiovascular risk factors. BMC Psychiatry 2009 1.29
29 Exendin-4 protects beta-cells from interleukin-1 beta-induced apoptosis by interfering with the c-Jun NH2-terminal kinase pathway. Diabetes 2008 1.27
30 Up-regulation of macrophage migration inhibitory factor gene and protein expression in glial tumor cells during hypoxic and hypoglycemic stress indicates a critical role for angiogenesis in glioblastoma multiforme. Am J Pathol 2003 1.27
31 Genome-wide meta-analysis for serum calcium identifies significantly associated SNPs near the calcium-sensing receptor (CASR) gene. PLoS Genet 2010 1.25
32 Prevalence, awareness, treatment and control of high blood pressure in a Swiss city general population: the CoLaus study. Eur J Cardiovasc Prev Rehabil 2009 1.22
33 Geriatric depression and vascular diseases: what are the links? J Affect Disord 2004 1.20
34 ICER induced by hyperglycemia represses the expression of genes essential for insulin exocytosis. EMBO J 2006 1.16
35 Lipoprotein distribution and biological variation of 24S- and 27-hydroxycholesterol in healthy volunteers. Atherosclerosis 2006 1.12
36 Alcohol drinking and cardiovascular risk in a population with high mean alcohol consumption. Am J Cardiol 2008 1.12
37 Elevated serum uric acid is associated with high circulating inflammatory cytokines in the population-based Colaus study. PLoS One 2011 1.11
38 Common genetic loci influencing plasma homocysteine concentrations and their effect on risk of coronary artery disease. Am J Clin Nutr 2013 1.08
39 [Towards a single society for specialists in family medicine and specialists in general internal medicine in Switzerland?]. Rev Med Suisse 2008 1.08
40 Insulin-secreting beta-cell dysfunction induced by human lipoproteins. J Biol Chem 2003 1.08
41 ["The union has the power"!]. Rev Med Suisse 2008 1.07
42 An angiotensin II- and NF-kappaB-dependent mechanism increases connexin 43 in murine arteries targeted by renin-dependent hypertension. Cardiovasc Res 2010 1.05
43 Prevalence of obesity and abdominal obesity in the Lausanne population. BMC Public Health 2008 1.05
44 Association between circulating cytokine levels, diabetes and insulin resistance in a population-based sample (CoLaus study). Clin Endocrinol (Oxf) 2013 1.03
45 Glucose represses connexin36 in insulin-secreting cells. J Cell Sci 2005 1.03
46 Methods for testing association between uncertain genotypes and quantitative traits. Biostatistics 2010 1.02
47 The repressor element silencing transcription factor (REST)-mediated transcriptional repression requires the inhibition of Sp1. J Biol Chem 2004 1.00
48 Multiple QTLs influencing triglyceride and HDL and total cholesterol levels identified in families with atherogenic dyslipidemia. J Lipid Res 2005 1.00
49 The Lausanne cohort Lc65+: a population-based prospective study of the manifestations, determinants and outcomes of frailty. BMC Geriatr 2008 0.99
50 Prevalence and factors associated with difficulty and intention to quit smoking in Switzerland. BMC Public Health 2011 0.99
51 Critical role of the transcriptional repressor neuron-restrictive silencer factor in the specific control of connexin36 in insulin-producing cell lines. J Biol Chem 2003 0.98
52 Interleukin-8 secretion by fibroblasts induced by low density lipoproteins is p38 MAPK-dependent and leads to cell spreading and wound closure. J Biol Chem 2005 0.98
53 Assessment of the capacity to consent to treatment in patients admitted to acute medical wards. BMC Med Ethics 2009 0.96
54 Serum uric acid and adiposity: deciphering causality using a bidirectional Mendelian randomization approach. PLoS One 2012 0.94
55 HDLs protect pancreatic β-cells against ER stress by restoring protein folding and trafficking. Diabetes 2012 0.93
56 Association between variants of the leptin receptor gene (LEPR) and overweight: a systematic review and an analysis of the CoLaus study. PLoS One 2011 0.92
57 ICER-1gamma overexpression drives palmitate-mediated connexin36 down-regulation in insulin-secreting cells. J Biol Chem 2007 0.92
58 Complexin I regulates glucose-induced secretion in pancreatic beta-cells. J Cell Sci 2004 0.92
59 Risk of falls and major bleeds in patients on oral anticoagulation therapy. Am J Med 2012 0.92
60 The scaffold protein IB1/JIP-1 is a critical mediator of cytokine-induced apoptosis in pancreatic beta cells. J Cell Sci 2003 0.92
61 Sex difference and the role of leptin in the association between high-sensitivity C-reactive protein and adiposity in two different populations. Eur J Epidemiol 2012 0.92
62 Not all inflammatory markers are linked to kidney function: results from a population-based study. Am J Nephrol 2012 0.91
63 Predictive accuracy and usefulness of calibration of the ESC SCORE in Switzerland. Eur J Cardiovasc Prev Rehabil 2008 0.91
64 Distribution of plasma levels of adiponectin and leptin in an adult Caucasian population. Clin Endocrinol (Oxf) 2009 0.91
65 The inter-rater reliability of the Pulmonary Embolism Severity Index. Thromb Haemost 2010 0.90
66 Hyperhomocysteinemia is independently associated with albuminuria in the population-based CoLaus study. BMC Public Health 2011 0.90
67 Low compliance with dietary recommendations for food intake among adults. Clin Nutr 2012 0.89
68 Opinions on tobacco control policies in Lausanne, Switzerland, 2003-2006. Prev Med 2010 0.89
69 Non-surgical pneumoperitoneum. Emerg Med J 2010 0.89
70 Impaired expression of the inducible cAMP early repressor accounts for sustained adipose CREB activity in obesity. Diabetes 2011 0.89
71 Population and economic impact of the 2013 ACC/AHA guidelines compared with European guidelines to prevent cardiovascular disease. Eur Heart J 2014 0.88
72 Prevalence, treatment and control of dyslipidaemia in Switzerland: still a long way to go. Eur J Cardiovasc Prev Rehabil 2010 0.88
73 Association between inflammatory and obesity markers in a Swiss population-based sample (CoLaus Study). Obes Facts 2012 0.88
74 Adipocytokines, hepatic and inflammatory biomarkers and incidence of type 2 diabetes. the CoLaus study. PLoS One 2012 0.88
75 Ambulatory blood pressure monitoring: a mean to stratify cardiovascular risk. Blood Press Monit 2007 0.88
76 Predictive accuracy of original and recalibrated Framingham risk score in the Swiss population. Int J Cardiol 2008 0.88
77 Increased connexin43 expression in human saphenous veins in culture is associated with intimal hyperplasia. J Vasc Surg 2005 0.88
78 IB1/JIP-1 controls JNK activation and increased during prostatic LNCaP cells neuroendocrine differentiation. Cell Signal 2005 0.87
79 Genome-wide association study identifies two loci strongly affecting transferrin glycosylation. Hum Mol Genet 2011 0.87
80 Levels and determinants of inflammatory biomarkers in a Swiss population-based sample (CoLaus study). PLoS One 2011 0.87
81 No interaction between alcohol consumption and HDL-related genes on HDL cholesterol levels. Atherosclerosis 2010 0.87
82 Association of statins with inflammatory cytokines: a population-based Colaus study. Atherosclerosis 2011 0.86
83 Prevalence of overweight and obesity among migrants in Switzerland: association with country of origin. Public Health Nutr 2011 0.86
84 Insulin modulation of luteinizing hormone secretion in normal female volunteers and lean polycystic ovary syndrome patients. Neuroendocrinology 2008 0.86
85 Identification and validation of copy number variants using SNP genotyping arrays from a large clinical cohort. BMC Genomics 2012 0.86
86 Antihypertensive drug treatment changes in the general population: the CoLaus study. BMC Pharmacol Toxicol 2014 0.86
87 No interactions between previously associated 2-hour glucose gene variants and physical activity or BMI on 2-hour glucose levels. Diabetes 2012 0.86
88 The scaffold protein IB1/JIP-1 controls the activation of JNK in rat stressed urothelium. J Cell Sci 2002 0.85
89 Cholesterol is the major component of native lipoproteins activating the p38 mitogen-activated protein kinases. Biol Chem 2005 0.85
90 Neuronal traits are required for glucose-induced insulin secretion. FEBS Lett 2004 0.85
91 Connexin-36 contributes to control function of insulin-producing cells. J Biol Chem 2003 0.85
92 Prevalence of normal weight obesity in Switzerland: effect of various definitions. Eur J Nutr 2008 0.85
93 Determinants and burden of chronic kidney disease in the population-based CoLaus study: a cross-sectional analysis. Nephrol Dial Transplant 2013 0.84
94 Estimating the risk of developing type 2 diabetes: a comparison of several risk scores: the Cohorte Lausannoise study. Diabetes Care 2011 0.84
95 Role of the JNK-interacting protein 1/islet brain 1 in cell degeneration in Alzheimer disease and diabetes. Brain Res Bull 2009 0.83
96 Neurotensin is a regulator of insulin secretion in pancreatic beta-cells. Int J Biochem Cell Biol 2010 0.83
97 Serum insulin and inflammatory markers in overweight individuals with and without dyslipidemia. J Clin Endocrinol Metab 2007 0.83
98 [Statin prescription in primary prevention: which cardiovascular risk score should be used in Switzerland?]. Rev Med Suisse 2010 0.83
99 Surrogate markers for atherosclerosis in overweight subjects with atherogenic dyslipidemia: the GEMS project. Angiology 2008 0.82
100 Serum calcium levels are associated with novel cardiometabolic risk factors in the population-based CoLaus study. PLoS One 2011 0.82
101 Expression of an uncleavable N-terminal RasGAP fragment in insulin-secreting cells increases their resistance toward apoptotic stimuli without affecting their glucose-induced insulin secretion. J Biol Chem 2005 0.82
102 Association of serum homocysteine with major depressive disorder: results from a large population-based study. Psychoneuroendocrinology 2013 0.81
103 The prevalence and management of cardiovascular risk factors in immigrant groups in Switzerland. Int J Public Health 2011 0.81
104 Aspirin use for the primary prevention of coronary heart disease: a population-based study in Switzerland. Prev Med 2007 0.81
105 The hairy and enhancer of split 1 is a negative regulator of the repressor element silencer transcription factor. FEBS Lett 2005 0.80
106 Current genetic data do not improve the prediction of type 2 diabetes mellitus: the CoLaus study. J Clin Endocrinol Metab 2012 0.80
107 Reduction of connexin36 content by ICER-1 contributes to insulin-secreting cells apoptosis induced by oxidized LDL particles. PLoS One 2013 0.80
108 Use of a Mendelian randomization approach to assess the causal relation of gamma-Glutamyltransferase with blood pressure and serum insulin levels. Am J Epidemiol 2010 0.80
109 Thyrotropin-releasing hormone-stimulated thyrotropin expression involves islet-brain-1/c-Jun N-terminal kinase interacting protein-1. Endocrinology 2004 0.80
110 Another (better) index of adiposity. Obesity (Silver Spring) 2012 0.80
111 Variations in IB1/JIP1 expression regulate susceptibility of beta-cells to cytokine-induced apoptosis irrespective of C-Jun NH2-terminal kinase signaling. Diabetes 2003 0.80
112 Caffeine intake and CYP1A2 variants associated with high caffeine intake protect non-smokers from hypertension. Hum Mol Genet 2012 0.79
113 Involvement of 4E-BP1 in the protection induced by HDLs on pancreatic beta-cells. Mol Endocrinol 2009 0.79
114 Validation of 7 type 2 diabetes mellitus risk scores in a population-based cohort: CoLaus study. Arch Intern Med 2012 0.79
115 Variant within the promoter region of the CHRNA3 gene associated with FTN dependence is not related to self-reported willingness to quit smoking. Nicotine Tob Res 2011 0.79
116 Psychiatric co-morbidities and cardiovascular risk factors in people with lifetime history of epilepsy of an urban community. Clin Neurol Neurosurg 2011 0.79
117 High expectation in non-evidence-based smoking cessation interventions among smokers--the CoLaus study. Prev Med 2011 0.79
118 LDLs stimulate p38 MAPKs and wound healing through SR-BI independently of Ras and PI3 kinase. J Lipid Res 2008 0.78
119 Evidence for tuning adipocytes ICER levels for obesity care. Adipocyte 2012 0.78
120 Female residents experiencing medical errors in general internal medicine: a qualitative study. BMC Med Educ 2014 0.78
121 Increased vulnerability to kainic acid-induced epileptic seizures in mice underexpressing the scaffold protein Islet-Brain 1/JIP-1. Eur J Neurosci 2003 0.78
122 Statins for cardiovascular prevention according to different strategies: a cost analysis. Am J Cardiovasc Drugs 2011 0.78
123 Splice variant-specific stabilization of JNKs by IB1/JIP1. Cell Signal 2007 0.78
124 The mif gene is transcriptionally regulated by glucose in insulin-secreting cells. Biochem Biophys Res Commun 2002 0.77
125 A genomewide association study of smoking relapse in four European population-based samples. Psychiatr Genet 2013 0.77
126 [Challenges and opportunities related to the creation of a unique society of specialists in general internal medicine in 2015]. Rev Med Suisse 2014 0.77
127 Public health impact of statin prescribing strategies based on JUPITER. Prev Med 2010 0.77
128 Who is at low risk for cardiovascular disease? An assessment of different definitions. Int J Cardiol 2012 0.77
129 Predictive factors of adrenal insufficiency in patients admitted to acute medical wards: a case control study. BMC Endocr Disord 2013 0.76
130 Associations between alcohol consumption and selected cytokines in a Swiss population-based sample (CoLaus study). Atherosclerosis 2012 0.76
131 Iron and transfusion medicine. Blood Rev 2013 0.76
132 Sociodemographic and Behavioural Determinants of a Healthy Diet in Switzerland. Ann Nutr Metab 2015 0.76
133 Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study. PLoS Genet 2016 0.75
134 Prospective study of insulin-like growth factor-I, insulin-like growth factor-binding protein 3, genetic variants in the IGF1 and IGFBP3 genes and risk of coronary artery disease. Int J Mol Epidemiol Genet 2011 0.75
135 [Internal medicine according to the new Swiss executives]. Rev Med Suisse 2006 0.75
136 Hospitalized women experiencing an episode of excessive oral anticoagulation had a higher bleeding risk than men. J Womens Health (Larchmt) 2009 0.75
137 [How to prevent functional decline: an acute care integrated model for the elderly]. Rev Med Suisse 2012 0.75
138 [Factors influencing today's Swiss medical interns. An interview]. Rev Med Suisse 2006 0.75
139 LDLs induce fibroblast spreading independently of the LDL receptor via activation of the p38 MAPK pathway. J Lipid Res 2003 0.75
140 ["The union has the power!": two years too late]. Rev Med Suisse 2010 0.75
141 Glucose-induced insulin secretion in dyslipidemic and normolipidemic patients with normal glucose tolerance. Diabetes Care 2005 0.75
142 No association between Parachlamydia infection and atherosclerosis. FEMS Immunol Med Microbiol 2008 0.75
143 Prevalence and characteristics of homeopathy users in a representative sample of the Lausanne population: CoLaus study. Pharmacoepidemiol Drug Saf 2008 0.75
144 A genetic variant in the catechol-O-methyl transferase (COMT) gene is related to age-dependent differences in the therapeutic effect of calcium-channel blockers. Medicine (Baltimore) 2017 0.75
145 [Association between alcohol consumption and cardiovascular risk factors: a narrative review]. Rev Med Suisse 2010 0.75
146 Major bleeding risk in anticoagulated patients receiving concomitant antiplatelet therapy: a prospective study. Thromb Res 2013 0.75
147 [Maintaining competencies in internal medicine]. Rev Med Suisse 2008 0.75
148 Lipoproteins and mitogen-activated protein kinase signaling: a role in atherogenesis? Curr Opin Lipidol 2006 0.75
149 Corrigendum: Novel loci affecting iron homeostasis and their effects in individuals at risk for hemochromatosis. Nat Commun 2015 0.75
150 [Extrapulmonary sarcoidosis: an unrecognized disease entity?]. Rev Med Suisse 2010 0.75
151 [Oral anticoagulation and the risk of major bleeding]. Rev Med Suisse 2007 0.75
152 [An anniversary and a crow!]. Rev Med Suisse 2011 0.75
153 [Internal medicine: quo vadis?]. Rev Med Suisse 2006 0.75
154 [The place of youth]. Rev Med Suisse 2010 0.75
155 [The charter on medical professionalism: a salutary reminder of our values]. Rev Med Suisse 2006 0.75
156 [Working together is a success]. Rev Med Suisse 2015 0.75
157 Cardiovascular risk estimation and eligibility for statins in primary prevention comparing different strategies. Am J Cardiol 2009 0.75
158 [In Process Citation]. Rev Med Suisse 2015 0.75
159 Clinical and biological determinants of kidney outcomes in a population-based cohort study. Kidney Blood Press Res 2014 0.75
160 Angiotensin receptor blockers are not associated with reduced inflammatory markers in the general population. J Hypertens 2015 0.75
161 Smoking offsets the metabolic benefits of parental longevity in women: the CoLaus study. Prev Med 2008 0.75
162 [Gap junctions and secretion]. Rev Med Suisse 2005 0.75
163 [In Process Citation]. Rev Med Suisse 2016 0.75
164 Correction: Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults. PLoS Genet 2017 0.75
165 Do you want some spiritual support? Different rates of positive response to chaplains' versus nurses' offer. J Pastoral Care Counsel 2014 0.75
166 [Immunocompromised HIV patient with lymphadenopathy and fever]. Rev Med Suisse 2010 0.75