Published in PLoS Genet on August 01, 2007
Inflammation and the Host Response to Injury (Trauma) | NCT00257231
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Cigarette smoking behaviors and time since quitting are associated with differential DNA methylation across the human genome. Hum Mol Genet (2012) 2.24
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A genome-wide gene expression signature of environmental geography in leukocytes of Moroccan Amazighs. PLoS Genet (2008) 2.19
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Significance analysis and statistical dissection of variably methylated regions. Biostatistics (2011) 1.74
A cross-platform analysis of 14,177 expression quantitative trait loci derived from lymphoblastoid cell lines. Genome Res (2013) 1.72
Whole-genome association mapping of gene expression in the human prefrontal cortex. Mol Psychiatry (2010) 1.69
Partitioning the heritability of Tourette syndrome and obsessive compulsive disorder reveals differences in genetic architecture. PLoS Genet (2013) 1.68
Multi-platform assessment of transcriptome profiling using RNA-seq in the ABRF next-generation sequencing study. Nat Biotechnol (2014) 1.68
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Heading down the wrong pathway: on the influence of correlation within gene sets. BMC Genomics (2010) 1.59
Pooling breast cancer datasets has a synergetic effect on classification performance and improves signature stability. BMC Genomics (2008) 1.45
CpG sites associated with cigarette smoking: analysis of epigenome-wide data from the Sister Study. Environ Health Perspect (2014) 1.44
Identifying and mitigating bias in next-generation sequencing methods for chromatin biology. Nat Rev Genet (2014) 1.44
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Genome-wide association study identifies five loci associated with susceptibility to pancreatic cancer in Chinese populations. Nat Genet (2011) 1.42
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Genomic innovations, transcriptional plasticity and gene loss underlying the evolution and divergence of two highly polyphagous and invasive Helicoverpa pest species. BMC Biol (2017) 1.39
Altered regulation and expression of genes by BET family of proteins in COPD patients. PLoS One (2017) 1.36
Joint modelling of confounding factors and prominent genetic regulators provides increased accuracy in genetical genomics studies. PLoS Comput Biol (2012) 1.36
miR-1202 is a primate-specific and brain-enriched microRNA involved in major depression and antidepressant treatment. Nat Med (2014) 1.35
Integrative modeling of eQTLs and cis-regulatory elements suggests mechanisms underlying cell type specificity of eQTLs. PLoS Genet (2013) 1.34
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Detecting and correcting systematic variation in large-scale RNA sequencing data. Nat Biotechnol (2014) 1.33
DNA methylation shows genome-wide association of NFIX, RAPGEF2 and MSRB3 with gestational age at birth. Int J Epidemiol (2012) 1.30
Deciphering normal blood gene expression variation--The NOWAC postgenome study. PLoS Genet (2010) 1.29
Extent, causes, and consequences of small RNA expression variation in human adipose tissue. PLoS Genet (2012) 1.28
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Association between SNPs and gene expression in multiple regions of the human brain. Transl Psychiatry (2012) 1.27
Joint genetic analysis of gene expression data with inferred cellular phenotypes. PLoS Genet (2011) 1.26
A comparison of feature selection and classification methods in DNA methylation studies using the Illumina Infinium platform. BMC Bioinformatics (2012) 1.26
Beyond modules and hubs: the potential of gene coexpression networks for investigating molecular mechanisms of complex brain disorders. Genes Brain Behav (2013) 1.25
Accounting for population stratification in DNA methylation studies. Genet Epidemiol (2014) 1.25
Genome-wide association study implicates NDST3 in schizophrenia and bipolar disorder. Nat Commun (2013) 1.25
Normalization and missing value imputation for label-free LC-MS analysis. BMC Bioinformatics (2012) 1.22
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Multi-dimensional correlations for gene coexpression and application to the large-scale data of Arabidopsis. Bioinformatics (2009) 1.17
Molecular signatures from omics data: from chaos to consensus. Biotechnol J (2012) 1.17
Critical reasoning on causal inference in genome-wide linkage and association studies. Trends Genet (2010) 1.15
Systems biology and gene networks in neurodevelopmental and neurodegenerative disorders. Nat Rev Genet (2015) 1.14
A-clustering: a novel method for the detection of co-regulated methylation regions, and regions associated with exposure. Bioinformatics (2013) 1.14
Genetic effects on gene expression across human tissues. Nature (2017) 1.13
Thawing Frozen Robust Multi-array Analysis (fRMA). BMC Bioinformatics (2011) 1.13
Making informed choices about microarray data analysis. PLoS Comput Biol (2010) 1.13
Correcting gene expression data when neither the unwanted variation nor the factor of interest are observed. Biostatistics (2015) 1.12
Characteristics and predictive value of blood transcriptome signature in males with autism spectrum disorders. PLoS One (2012) 1.09
Comparative RNA-Seq and microarray analysis of gene expression changes in B-cell lymphomas of Canis familiaris. PLoS One (2013) 1.09
Large-Scale trans-eQTLs Affect Hundreds of Transcripts and Mediate Patterns of Transcriptional Co-regulation. Am J Hum Genet (2017) 1.08
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Principal components analysis corrects for stratification in genome-wide association studies. Nat Genet (2006) 115.71
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Gene-expression profiles in hereditary breast cancer. N Engl J Med (2001) 29.80
Genetic analysis of genome-wide variation in human gene expression. Nature (2004) 27.28
The Connectivity Map: using gene-expression signatures to connect small molecules, genes, and disease. Science (2006) 25.99
Genetic dissection of transcriptional regulation in budding yeast. Science (2002) 25.01
Genetics of gene expression surveyed in maize, mouse and man. Nature (2003) 22.17
Singular value decomposition for genome-wide expression data processing and modeling. Proc Natl Acad Sci U S A (2000) 18.42
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Genetic interactions between polymorphisms that affect gene expression in yeast. Nature (2005) 6.42
Multiple locus linkage analysis of genomewide expression in yeast. PLoS Biol (2005) 5.61
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Integrative analysis of the cancer transcriptome. Nat Genet (2005) 4.44
A transcriptional profile of aging in the human kidney. PLoS Biol (2004) 3.69
Correlation between gene expression levels and limitations of the empirical bayes methodology for finding differentially expressed genes. Stat Appl Genet Mol Biol (2005) 3.25
A reanalysis of a published Affymetrix GeneChip control dataset. Genome Biol (2006) 3.17
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Molecular classification of familial non-BRCA1/BRCA2 breast cancer. Proc Natl Acad Sci U S A (2003) 2.10
Assessing stability of gene selection in microarray data analysis. BMC Bioinformatics (2006) 1.96
A new approach to intensity-dependent normalization of two-channel microarrays. Biostatistics (2006) 1.86
Molecular heterogeneity of inflammatory breast cancer: a hyperproliferative phenotype. Clin Cancer Res (2006) 1.67
Some comments on instability of false discovery rate estimation. J Bioinform Comput Biol (2006) 1.51
Treating expression levels of different genes as a sample in microarray data analysis: is it worth a risk? Stat Appl Genet Mol Biol (2006) 1.45
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Estimation of false discovery proportion under general dependence. Bioinformatics (2006) 1.35
Mapping the genetic architecture of gene expression in human liver. PLoS Biol (2008) 19.44
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A genomic storm in critically injured humans. J Exp Med (2011) 6.67
Genetic interactions between polymorphisms that affect gene expression in yeast. Nature (2005) 6.42
Assigning significance to peptides identified by tandem mass spectrometry using decoy databases. J Proteome Res (2007) 5.57
The sva package for removing batch effects and other unwanted variation in high-throughput experiments. Bioinformatics (2012) 4.48
A general framework for multiple testing dependence. Proc Natl Acad Sci U S A (2008) 4.27
A reanalysis of a published Affymetrix GeneChip control dataset. Genome Biol (2006) 3.17
EDGE: extraction and analysis of differential gene expression. Bioinformatics (2005) 3.14
On the design and analysis of gene expression studies in human populations. Nat Genet (2007) 3.07
Posterior error probabilities and false discovery rates: two sides of the same coin. J Proteome Res (2007) 2.61
A genome-wide gene expression signature of environmental geography in leukocytes of Moroccan Amazighs. PLoS Genet (2008) 2.19
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Harnessing naturally randomized transcription to infer regulatory relationships among genes. Genome Biol (2007) 1.94
Calibrating the performance of SNP arrays for whole-genome association studies. PLoS Genet (2008) 1.86
A new approach to intensity-dependent normalization of two-channel microarrays. Biostatistics (2006) 1.86
Relaxed significance criteria for linkage analysis. Genetics (2006) 1.70
Human transcriptome array for high-throughput clinical studies. Proc Natl Acad Sci U S A (2011) 1.62
Mapping gene expression quantitative trait loci by singular value decomposition and independent component analysis. BMC Bioinformatics (2008) 1.51
Design and analysis of Bar-seq experiments. G3 (Bethesda) (2014) 1.48
Non-parametric estimation of posterior error probabilities associated with peptides identified by tandem mass spectrometry. Bioinformatics (2008) 1.47
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In vivo regulation of human skeletal muscle gene expression by thyroid hormone. Genome Res (2002) 1.33
Normalization of two-channel microarrays accounting for experimental design and intensity-dependent relationships. Genome Biol (2007) 1.29
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Dissecting inflammatory complications in critically injured patients by within-patient gene expression changes: a longitudinal clinical genomics study. PLoS Med (2011) 1.11
Optimality driven nearest centroid classification from genomic data. PLoS One (2007) 0.98
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Identifying and mapping cell-type-specific chromatin programming of gene expression. Proc Natl Acad Sci U S A (2014) 0.85
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