Published in J Cell Biol on October 01, 2007
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Identification of an Aurora-A/PinsLINKER/Dlg spindle orientation pathway using induced cell polarity in S2 cells. Cell (2009) 2.30
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Dynamic localization of LIN-5 and GPR-1/2 to cortical force generation domains during spindle positioning. Dev Biol (2007) 1.24
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Local cortical pulling-force repression switches centrosomal centration and posterior displacement in C. elegans. J Cell Biol (2007) 1.07
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Mammalian Pins is a conformational switch that links NuMA to heterotrimeric G proteins. Cell (2004) 3.52
The NuMA-related Mud protein binds Pins and regulates spindle orientation in Drosophila neuroblasts. Nat Cell Biol (2006) 3.23
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A mammalian Partner of inscuteable binds NuMA and regulates mitotic spindle organization. Nat Cell Biol (2001) 2.73
Cortical microtubule contacts position the spindle in C. elegans embryos. Cell (2007) 2.69
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The Drosophila NuMA Homolog Mud regulates spindle orientation in asymmetric cell division. Dev Cell (2006) 2.53
Drosophila Pins-binding protein Mud regulates spindle-polarity coupling and centrosome organization. Nat Cell Biol (2006) 2.52
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Dynein light chains of the Roadblock/LC7 group belong to an ancient protein superfamily implicated in NTPase regulation. Curr Biol (2000) 1.51
LET-99 determines spindle position and is asymmetrically enriched in response to PAR polarity cues in C. elegans embryos. Development (2002) 1.44
LET-99 opposes Galpha/GPR signaling to generate asymmetry for spindle positioning in response to PAR and MES-1/SRC-1 signaling. Development (2003) 1.38
Myosin and the PAR proteins polarize microfilament-dependent forces that shape and position mitotic spindles in Caenorhabditis elegans. J Cell Biol (2003) 1.37
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LIN-5 is a novel component of the spindle apparatus required for chromosome segregation and cleavage plane specification in Caenorhabditis elegans. J Cell Biol (2000) 1.17
Dynamic behavior of microtubules during dynein-dependent nuclear migrations of meiotic prophase in fission yeast. Mol Biol Cell (2001) 1.16
A genomewide screen for suppressors of par-2 uncovers potential regulators of PAR protein-dependent cell polarity in Caenorhabditis elegans. Genetics (2006) 1.15
The LC7 light chains of Chlamydomonas flagellar dyneins interact with components required for both motor assembly and regulation. Mol Biol Cell (2004) 1.07
Heterotrimeric G proteins and regulation of size asymmetry during cell division. Curr Opin Cell Biol (2005) 0.95
Systematic functional analysis of the Caenorhabditis elegans genome using RNAi. Nature (2003) 26.58
The promise and perils of Wnt signaling through beta-catenin. Science (2002) 6.11
The BTB protein MEL-26 is a substrate-specific adaptor of the CUL-3 ubiquitin-ligase. Nature (2003) 4.18
Loss of human Greatwall results in G2 arrest and multiple mitotic defects due to deregulation of the cyclin B-Cdc2/PP2A balance. Proc Natl Acad Sci U S A (2010) 4.07
Centrosome maturation and mitotic spindle assembly in C. elegans require SPD-5, a protein with multiple coiled-coil domains. Dev Cell (2002) 3.35
The substrate of Greatwall kinase, Arpp19, controls mitosis by inhibiting protein phosphatase 2A. Science (2010) 3.27
Cdc48/p97 promotes reformation of the nucleus by extracting the kinase Aurora B from chromatin. Nature (2007) 2.84
Kinetochore localization of spindle checkpoint proteins: who controls whom? Mol Biol Cell (2004) 2.50
Greatwall maintains mitosis through regulation of PP2A. EMBO J (2009) 2.22
A Formin Homology protein and a profilin are required for cytokinesis and Arp2/3-independent assembly of cortical microfilaments in C. elegans. Curr Biol (2002) 2.16
The conserved protein DCN-1/Dcn1p is required for cullin neddylation in C. elegans and S. cerevisiae. Nature (2005) 2.01
Neddylation and deneddylation of CUL-3 is required to target MEI-1/Katanin for degradation at the meiosis-to-mitosis transition in C. elegans. Curr Biol (2003) 1.95
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Cytoskeletal regulation by the Nedd8 ubiquitin-like protein modification pathway. Science (2002) 1.79
Axon regeneration pathways identified by systematic genetic screening in C. elegans. Neuron (2011) 1.78
Inhibition of Rac by the GAP activity of centralspindlin is essential for cytokinesis. Science (2008) 1.74
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Multiple Wnt signaling pathways converge to orient the mitotic spindle in early C. elegans embryos. Dev Cell (2004) 1.54
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Mutations in Caenorhabditis elegans cytoplasmic dynein components reveal specificity of neuronal retrograde cargo. J Neurosci (2004) 1.46
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APC/Fizzy-Related targets Aurora-A kinase for proteolysis. EMBO Rep (2002) 1.45
The anaphase-promoting complex and separin are required for embryonic anterior-posterior axis formation. Dev Cell (2002) 1.43
Caenorhabditis elegans SAND-1 is essential for RAB-7 function in endosomal traffic. EMBO J (2007) 1.39
Characterization of anillin mutants reveals essential roles in septin localization and plasma membrane integrity. Development (2005) 1.37
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A spindle checkpoint functions during mitosis in the early Caenorhabditis elegans embryo. Mol Biol Cell (2004) 1.37
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Characterization of the mechanisms controlling Greatwall activity. Mol Cell Biol (2011) 1.25
Mitotic spindle (DIS)orientation and DISease: cause or consequence? J Cell Biol (2012) 1.21
Control of nuclear centration in the C. elegans zygote by receptor-independent Galpha signaling and myosin II. J Cell Biol (2007) 1.20
URI-1 is required for DNA stability in C. elegans. Development (2006) 1.16
Xkid is degraded in a D-box, KEN-box, and A-box-independent pathway. Mol Cell Biol (2003) 1.16
Constant regulation of both the MPF amplification loop and the Greatwall-PP2A pathway is required for metaphase II arrest and correct entry into the first embryonic cell cycle. J Cell Sci (2010) 1.15
A genomewide screen for suppressors of par-2 uncovers potential regulators of PAR protein-dependent cell polarity in Caenorhabditis elegans. Genetics (2006) 1.15
A survey of new temperature-sensitive, embryonic-lethal mutations in C. elegans: 24 alleles of thirteen genes. PLoS One (2011) 1.15
A casein kinase 1 and PAR proteins regulate asymmetry of a PIP(2) synthesis enzyme for asymmetric spindle positioning. Dev Cell (2008) 1.13
The D-Box-activating domain (DAD) is a new proteolysis signal that stimulates the silent D-Box sequence of Aurora-A. EMBO Rep (2002) 1.09
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PAR-4/LKB1 mobilizes nonmuscle myosin through anillin to regulate C. elegans embryonic polarization and cytokinesis. Curr Biol (2011) 1.03
Caenorhabditis elegans EFA-6 limits microtubule growth at the cell cortex. Nat Cell Biol (2010) 1.02
A new role for Mos in Xenopus oocyte maturation: targeting Myt1 independently of MAPK. Development (2002) 1.01
Conditional dominant mutations in the Caenorhabditis elegans gene act-2 identify cytoplasmic and muscle roles for a redundant actin isoform. Mol Biol Cell (2006) 0.99
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SPAT-1/Bora acts with Polo-like kinase 1 to regulate PAR polarity and cell cycle progression. Development (2010) 0.92
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