Published in Clin Trials on January 01, 2007
Suicidal thoughts and behavior with antidepressant treatment: reanalysis of the randomized placebo-controlled studies of fluoxetine and venlafaxine. Arch Gen Psychiatry (2012) 3.24
Current Directions in Mediation Analysis. Curr Dir Psychol Sci (2009) 2.52
Limited role of culture conversion for decision-making in individual patient care and for advancing novel regimens to confirmatory clinical trials. BMC Med (2016) 1.61
Subjective social status affects smoking abstinence during acute withdrawal through affective mediators. Addiction (2010) 1.60
Mediating effects of smoking and chronic obstructive pulmonary disease on the relation between the CHRNA5-A3 genetic locus and lung cancer risk. Cancer (2010) 1.55
A commentary on current practice in mediating variable analyses in behavioural nutrition and physical activity. Public Health Nutr (2008) 1.51
An introduction to causal inference. Int J Biostat (2010) 1.48
Climate change and climate variability: personal motivation for adaptation and mitigation. Environ Health (2011) 1.35
Mechanisms of change in extended cognitive behavioral treatment for tobacco dependence. Drug Alcohol Depend (2010) 1.15
Bayesian inference for causal mediation effects using principal stratification with dichotomous mediators and outcomes. Biostatistics (2010) 1.13
Commentary on "Mediation Analysis and Categorical Variables: The Final Frontier" by Dawn Iacobucci. J Consum Psychol (2012) 1.08
Method for evaluating multiple mediators: mediating effects of smoking and COPD on the association between the CHRNA5-A3 variant and lung cancer risk. PLoS One (2012) 1.00
Causality, mediation and time: a dynamic viewpoint. J R Stat Soc Ser A Stat Soc (2012) 1.00
A Culturally Adapted Smoking Cessation Intervention for Korean Americans: A Mediating Effect of Perceived Family Norm Toward Quitting. J Immigr Minor Health (2015) 0.98
The relation between social cohesion and smoking cessation among Black smokers, and the potential role of psychosocial mediators. Ann Behav Med (2013) 0.97
Effects of Cognitive Enhancement Therapy on Employment Outcomes in Early Schizophrenia: Results From a Two-Year Randomized Trial. Res Soc Work Pract (2011) 0.96
Diabetes in relation to biliary tract cancer and stones: a population-based study in Shanghai, China. Br J Cancer (2010) 0.94
Alcohol and marijuana use in the context of tobacco dependence treatment: impact on outcome and mediation of effect. Nicotine Tob Res (2012) 0.89
Female Partner Acceptance as a Predictor of Men's Readiness to Undergo Voluntary Medical Male Circumcision in Zambia: The Spear and Shield Project. AIDS Behav (2016) 0.88
Role of nicotine dependence on the relationship between variants in the nicotinic receptor genes and risk of lung adenocarcinoma. PLoS One (2014) 0.86
Mediators of the association between driving cessation and mortality among older adults. J Aging Health (2013) 0.85
Prospective study of factors predicting adherence to surveillance mammography in women treated for breast cancer. J Clin Oncol (2012) 0.85
A moderating role for gender in racial/ethnic disparities in alcohol services utilization: results from the 2000 to 2010 national alcohol surveys. Alcohol Clin Exp Res (2014) 0.83
Social support mediates the association of health literacy and depression among racially/ethnically diverse smokers with low socioeconomic status. J Behav Med (2014) 0.82
Design of a randomized controlled trial for multiple cancer risk behaviors among Spanish-speaking Mexican-origin smokers. BMC Public Health (2013) 0.82
Improving Our Ability to Evaluate Underlying Mechanisms of Behavioral Onset and Other Event Occurrence Outcomes: A Discrete-Time Survival Mediation Model. Eval Health Prof (2013) 0.82
Alcohol and drug treatment involvement, 12-step attendance and abstinence: 9-year cross-lagged analysis of adults in an integrated health plan. J Subst Abuse Treat (2013) 0.82
Mediators and moderators in early intervention research. Early Interv Psychiatry (2010) 0.81
Power and sample size calculations for evaluating mediation effects in longitudinal studies. Stat Methods Med Res (2012) 0.80
Granulation response and partial wound closure predict healing in clinical trials on advanced diabetes foot ulcers treated with recombinant human epidermal growth factor. Diabetes Care (2012) 0.78
New aQTL SNPs for the CYP2D6 identified by a novel mediation analysis of genome-wide SNP arrays, gene expression arrays, and CYP2D6 activity. Biomed Res Int (2013) 0.78
Neighborhood vigilance, health locus of control, and smoking abstinence. Am J Health Behav (2013) 0.78
The interplay between child and maternal health: reciprocal relationships and cumulative disadvantage during childhood and adolescence. J Health Soc Behav (2014) 0.78
The influence of HIV disease events/stages on smoking attitudes and behaviors: project STATE (Study of Tobacco Attitudes and Teachable Events). BMC Public Health (2014) 0.77
Association between serotonin transporter genotype, brain structure and adolescent-onset major depressive disorder: a longitudinal prospective study. Transl Psychiatry (2014) 0.77
An internet-based adolescent depression preventive intervention: study protocol for a randomized control trial. Trials (2015) 0.77
Robust mediation analysis based on median regression. Psychol Methods (2013) 0.77
A Bayesian Approach for Estimating Mediation Effects with Missing Data. Multivariate Behav Res (2013) 0.77
The role of a parental history of Balkan endemic nephropathy in the occurrence of BEN: a prospective study. Int J Nephrol Renovasc Dis (2012) 0.77
Race moderates the effect of menthol cigarette use on short-term smoking abstinence. Nicotine Tob Res (2013) 0.76
Global Sensory Impairment in Older Adults in the United States. J Am Geriatr Soc (2016) 0.76
Mediators of a smoking cessation intervention for persons living with HIV/AIDS. Drug Alcohol Depend (2014) 0.76
Alcohol problem recognition and help seeking in adolescents and young adults at varying genetic and environmental risk. Drug Alcohol Depend (2015) 0.75
Non-linear mixed models in the analysis of mediated longitudinal data with binary outcomes. BMC Med Res Methodol (2012) 0.75
Causal mediation analysis in the context of clinical research. Ann Transl Med (2016) 0.75
Mediation Analysis with Survival Outcomes: Accelerated Failure Time vs. Proportional Hazards Models. Front Psychol (2016) 0.75
Mediation from multilevel to structural equation modeling. Ann Nutr Metab (2014) 0.75
Sample Size for Joint Testing of Indirect Effects. Prev Sci (2015) 0.75
Assessing natural direct and indirect effects for a continuous exposure and a dichotomous outcome. J Stat Theory Pract (2016) 0.75
Poor, Unsafe, and Overweight: The Role of Feeling Unsafe at School in Mediating the Association Among Poverty Exposure, Youth Screen Time, Physical Activity, and Weight Status. Am J Epidemiol (2015) 0.75
Interrelationship Between Alcohol Intake and Endogenous Sex-Steroid Hormones on Diabetes Risk in Postmenopausal Women. J Am Coll Nutr (2015) 0.75
On the (In)Validity of Tests of Simple Mediation: Threats and Solutions. Soc Personal Psychol Compass (2016) 0.75
Best (but oft-forgotten) practices: mediation analysis. Am J Clin Nutr (2017) 0.75
The moderator-mediator variable distinction in social psychological research: conceptual, strategic, and statistical considerations. J Pers Soc Psychol (1986) 124.55
A comparison of methods to test mediation and other intervening variable effects. Psychol Methods (2002) 34.84
Models for longitudinal data: a generalized estimating equation approach. Biometrics (1988) 27.90
A Simulation Study of Mediated Effect Measures. Multivariate Behav Res (1995) 15.44
Principal stratification in causal inference. Biometrics (2002) 12.34
Surrogate endpoints in clinical trials: definition and operational criteria. Stat Med (1989) 11.07
Surrogate end points in clinical trials: are we being misled? Ann Intern Med (1996) 9.81
Statistical validation of intermediate endpoints for chronic diseases. Stat Med (1992) 7.44
Sample size for studying intermediate endpoints within intervention trails or observational studies. Am J Epidemiol (1992) 6.92
A multicommunity trial for primary prevention of adolescent drug abuse. Effects on drug use prevalence. JAMA (1989) 5.31
Estimating the proportion of treatment effect explained by a surrogate marker. Stat Med (1997) 4.64
The validation of surrogate endpoints in meta-analyses of randomized experiments. Biostatistics (2000) 4.05
Multilevel mediation modeling in group-based intervention studies. Eval Rev (1999) 3.78
Criteria for the validation of surrogate endpoints in randomized experiments. Biometrics (1998) 3.72
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Preventing drug abuse in schools: social and competence enhancement approaches targeting individual-level etiologic factors. Addict Behav (2000) 2.41
On meta-analytic assessment of surrogate outcomes. Biostatistics (2000) 2.41
Statistical challenges in the evaluation of surrogate endpoints in randomized trials. Control Clin Trials (2002) 1.98
An evaluation of Safe Dates, an adolescent dating violence prevention program. Am J Public Health (1998) 1.86
Lipoproteins as mediators for the effects of alcohol consumption and cigarette smoking on cardiovascular mortality: results form the Lipid Research Clinics Follow-up Study. Am J Epidemiol (1987) 1.81
Statistical and mathematical modeling of the AIDS epidemic. Papers from a conference. Baltimore, Maryland, 17-18 November, 1987. Stat Med (1989) 0.85
Equivalence of the mediation, confounding and suppression effect. Prev Sci (2000) 13.92
Calculating structures and free energies of complex molecules: combining molecular mechanics and continuum models. Acc Chem Res (2000) 10.78
A new class of membrane-bound chemokine with a CX3C motif. Nature (1997) 7.87
NURD, a novel complex with both ATP-dependent chromatin-remodeling and histone deacetylase activities. Mol Cell (1998) 7.58
Negative feedback regulation of TGF-beta signaling by the SnoN oncoprotein. Science (1999) 7.51
Viral resistance to human immunodeficiency virus type 1-specific pyridinone reverse transcriptase inhibitors. J Virol (1991) 7.01
Binding and stimulation of HIV-1 integrase by a human homolog of yeast transcription factor SNF5. Science (1994) 5.47
Co-adjuvant effects of retinoic acid and IL-15 induce inflammatory immunity to dietary antigens. Nature (2011) 5.41
Rapid evolution of male reproductive genes in the descent of man. Nature (2000) 5.33
Identifying tumor suppressors in genetic mosaics: the Drosophila lats gene encodes a putative protein kinase. Development (1995) 5.18
Positron emission tomography in evaluation of dementia: Regional brain metabolism and long-term outcome. JAMA (2001) 5.13
Rapid and phosphoinositol-dependent binding of the SWI/SNF-like BAF complex to chromatin after T lymphocyte receptor signaling. Cell (1998) 4.95
The effect of corticosteroids for acute optic neuritis on the subsequent development of multiple sclerosis. The Optic Neuritis Study Group. N Engl J Med (1993) 4.34
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Prospective study of radioimmunoassay for antibodies against neutrophil cytoplasm in diagnosis of systemic vasculitis. Lancet (1987) 4.20
Direct text entry in electronic progress notes. An evaluation of input errors. Methods Inf Med (2003) 4.00
Proximal impact of two first-grade preventive interventions on the early risk behaviors for later substance abuse, depression, and antisocial behavior. Am J Community Psychol (1999) 3.98
Neural activity related to drug craving in cocaine addiction. Arch Gen Psychiatry (2001) 3.84
The effect of the level of aggression in the first grade classroom on the course and malleability of aggressive behavior into middle school. Dev Psychopathol (1998) 3.39
Comparison of the lay Diagnostic Interview Schedule and a standardized psychiatric diagnosis. Experience in eastern Baltimore. Arch Gen Psychiatry (1985) 3.18
The human SWI/SNF-B chromatin-remodeling complex is related to yeast rsc and localizes at kinetochores of mitotic chromosomes. Proc Natl Acad Sci U S A (2000) 3.16
Reversal of impaired splenic function in patients with nephritis or vasculitis (or both) by plasma exchange. N Engl J Med (1979) 3.02
Immunosuppression and plasma-exchange in the treatment of Goodpasture's syndrome. Lancet (1976) 3.00
The hemostatic defect produced by carbenicillin. N Engl J Med (1974) 2.99
An evaluation of the PCAT examination based on academic performance. Am J Pharm Educ (1977) 2.99
BRCA1 is associated with a human SWI/SNF-related complex: linking chromatin remodeling to breast cancer. Cell (2000) 2.94
Association of alkaline phosphatase with an autoantigen recognised by circulating anti-neutrophil antibodies in systemic vasculitis. Lancet (1987) 2.85
Zonulin, a newly discovered modulator of intestinal permeability, and its expression in coeliac disease. Lancet (2000) 2.82
NMDA receptors mediate calcium accumulation in myelin during chemical ischaemia. Nature (2005) 2.74
Processing of the notch ligand delta by the metalloprotease Kuzbanian. Science (1999) 2.71
Paternal population history of East Asia: sources, patterns, and microevolutionary processes. Am J Hum Genet (2001) 2.71
A specificity and targeting subunit of a human SWI/SNF family-related chromatin-remodeling complex. Mol Cell Biol (2000) 2.70
Ribosomal protein S7 as a novel modulator of p53-MDM2 interaction: binding to MDM2, stabilization of p53 protein, and activation of p53 function. Oncogene (2007) 2.68
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Safety of hydroxyurea in children with sickle cell anemia: results of the HUG-KIDS study, a phase I/II trial. Pediatric Hydroxyurea Group. Blood (1999) 2.59
Atrial G protein-activated K+ channel: expression cloning and molecular properties. Proc Natl Acad Sci U S A (1993) 2.57
Sino-MONICA project: a collaborative study on trends and determinants in cardiovascular diseases in China, Part i: morbidity and mortality monitoring. Circulation (2001) 2.56
Use of MM-PBSA in reproducing the binding free energies to HIV-1 RT of TIBO derivatives and predicting the binding mode to HIV-1 RT of efavirenz by docking and MM-PBSA. J Am Chem Soc (2001) 2.55
Hormonal changes in the grains of rice subjected to water stress during grain filling. Plant Physiol (2001) 2.52
The Ski oncoprotein interacts with the Smad proteins to repress TGFbeta signaling. Genes Dev (1999) 2.52
Dietary agents in cancer prevention: flavonoids and isoflavonoids. Pharmacol Ther (2001) 2.51
Genetic influence on the structural variations of the abnormal prion protein. Proc Natl Acad Sci U S A (2000) 2.46
Microscopic polyarteritis: presentation, pathology and prognosis. Q J Med (1985) 2.46
Treatment and survival in breast cancer in the Eastern Region of England. Ann Oncol (2009) 2.45
All-cause mortality and cardiovascular disease mortality in three American Indian populations, aged 45-74 years, 1984-1988. The Strong Heart Study. Am J Epidemiol (1998) 2.43
Biomarker risk assessment and bladder cancer detection in a cohort exposed to benzidine. J Natl Cancer Inst (2001) 2.41
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Pattern of marine mass extinction near the Permian-Triassic boundary in South China. Science (2000) 2.38
De novo amyloid proteins from designed combinatorial libraries. Proc Natl Acad Sci U S A (1999) 2.38
Predicting caries in permanent teeth from caries in primary teeth: an eight-year cohort study. J Dent Res (2002) 2.35
ATPase activity of the cystic fibrosis transmembrane conductance regulator. J Biol Chem (1996) 2.33
A randomized controlled phase III trial of recombinant human granulocyte colony-stimulating factor (filgrastim) for treatment of severe chronic neutropenia. Blood (1993) 2.29
Regulation of Ca2+ signaling in transgenic mouse cardiac myocytes overexpressing calsequestrin. J Clin Invest (1998) 2.29
Relapses in Wegener's granulomatosis: the role of infection. Br Med J (1980) 2.29
Graft fixation in cruciate ligament reconstruction. Am J Sports Med (2001) 2.28
A family of chromatin remodeling factors related to Williams syndrome transcription factor. Proc Natl Acad Sci U S A (2000) 2.24
CCR6, a CC chemokine receptor that interacts with macrophage inflammatory protein 3alpha and is highly expressed in human dendritic cells. J Exp Med (1997) 2.24
The immunodominant major histocompatibility complex class I-restricted antigen of a murine colon tumor derives from an endogenous retroviral gene product. Proc Natl Acad Sci U S A (1996) 2.24
TRAPP I implicated in the specificity of tethering in ER-to-Golgi transport. Mol Cell (2001) 2.20
Quality of life for children with fecal incontinence after surgically corrected anorectal malformation. J Pediatr Surg (2000) 2.17
Mortality and cardiovascular disease among older live kidney donors. Am J Transplant (2014) 2.16
The C3(1)/SV40 T-antigen transgenic mouse model of mammary cancer: ductal epithelial cell targeting with multistage progression to carcinoma. Oncogene (2000) 2.15
A clinician-driven automated system for integration of pharmacogenetic interpretations into an electronic medical record. Clin Pharmacol Ther (2012) 2.12
The minor histocompatibility antigen HA-1: a diallelic gene with a single amino acid polymorphism. Science (1998) 2.11
Validity of the ten questions screened for childhood disability: results from population-based studies in Bangladesh, Jamaica, and Pakistan. Epidemiology (1994) 2.10
Defective reticuloendothelial system function in rheumatoid arthritis. Lancet (1979) 2.10
Hydration of fat-free body mass: new physiological modeling approach. Am J Physiol (1999) 2.09
Performance characteristics of a whole-body PET scanner. J Nucl Med (1994) 2.08
Non-invasive prenatal testing for trisomies 21, 18 and 13: clinical experience from 146,958 pregnancies. Ultrasound Obstet Gynecol (2015) 2.07
Wegener's granulomatosis: observations on 18 patients with severe renal disease. Q J Med (1983) 2.07
Identification of early recurrence of primary central nervous system tumors by [18F]fluorodeoxyglucose positron emission tomography. Ann Neurol (1991) 2.05
Actinonin, a naturally occurring antibacterial agent, is a potent deformylase inhibitor. Biochemistry (2000) 2.03
Repeatability of the Pedar-X in-shoe pressure measuring system. Foot Ankle Surg (2009) 2.03
Characterization of SWI/SNF protein expression in human breast cancer cell lines and other malignancies. J Cell Physiol (2001) 2.02
Matrix metalloproteinase-2 contributes to ischemia-reperfusion injury in the heart. Circulation (2000) 2.01
A frame shift mutation in the DNA-binding domain of the androgen receptor gene associated with complete androgen insensitivity, persistent müllerian structures, and germ cell tumors in dysgenetic gonads. Fertil Steril (1999) 2.00
Hamstring tendon grafts for reconstruction of the anterior cruciate ligament: biomechanical evaluation of the use of multiple strands and tensioning techniques. J Bone Joint Surg Am (1999) 1.98
Cognitive functioning and brain magnetic resonance imaging in children with sickle Cell disease. Neuropsychology Committee of the Cooperative Study of Sickle Cell Disease. Pediatrics (1996) 1.98
The regulation of glucose-excited neurons in the hypothalamic arcuate nucleus by glucose and feeding-relevant peptides. Diabetes (2004) 1.96
Cutting edge: the orphan chemokine receptor G protein-coupled receptor-2 (GPR-2, CCR10) binds the skin-associated chemokine CCL27 (CTACK/ALP/ILC). J Immunol (2000) 1.95
Developmental epidemiologically based preventive trials: baseline modeling of early target behaviors and depressive symptoms. Am J Community Psychol (1991) 1.94
The 3'-end-processing factor CPSF is required for the splicing of single-intron pre-mRNAs in vivo. RNA (2001) 1.94
HEF1 is a necessary and specific downstream effector of FAK that promotes the migration of glioblastoma cells. Oncogene (2006) 1.94
Down-regulation of cyclin D1 expression by prostaglandin A(2) is mediated by enhanced cyclin D1 mRNA turnover. Mol Cell Biol (2000) 1.93
Enhanced allergic tissue injury in Goodpasture's syndrome by intercurrent bacterial infection. Br Med J (1977) 1.92
Intraocular lens power calculation after laser in situ keratomileusis for myopia and hyperopia: a standardized approach. Cornea (2001) 1.90
H36-alpha 7 is a novel integrin alpha chain that is developmentally regulated during skeletal myogenesis. J Cell Biol (1992) 1.89
Prognosis after immunosuppression of patients with crescentic nephritis requiring dialysis. Lancet (1983) 1.87
Curbing the nonsense: the activation and regulation of mRNA surveillance. Genes Dev (2001) 1.87
Caspase and calpain activation both contribute to sepsis-induced diaphragmatic weakness. J Appl Physiol (1985) (2009) 1.86
Harvesting energy from the marine sediment--water interface. Environ Sci Technol (2001) 1.85
Non-invasive prenatal testing for fetal chromosomal abnormalities by low-coverage whole-genome sequencing of maternal plasma DNA: review of 1982 consecutive cases in a single center. Ultrasound Obstet Gynecol (2014) 1.85
Chemical constituents from Dendrobium densiflorum. Phytochemistry (2001) 1.82
A computational approach to simplifying the protein folding alphabet. Nat Struct Biol (1999) 1.82
Trp1, a candidate protein for the store-operated Ca(2+) influx mechanism in salivary gland cells. J Biol Chem (2000) 1.82
The EH and SH3 domain Ese proteins regulate endocytosis by linking to dynamin and Eps15. EMBO J (1999) 1.82