Published in Development on April 01, 1995
The hippo signaling pathway in development and cancer. Dev Cell (2010) 10.54
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The TEAD/TEF family of transcription factor Scalloped mediates Hippo signaling in organ size control. Dev Cell (2008) 4.90
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The Drosophila Ste20 family kinase dMST functions as a tumor suppressor by restricting cell proliferation and promoting apoptosis. Genes Dev (2003) 3.53
Cell detachment activates the Hippo pathway via cytoskeleton reorganization to induce anoikis. Genes Dev (2012) 3.48
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Kibra functions as a tumor suppressor protein that regulates Hippo signaling in conjunction with Merlin and Expanded. Dev Cell (2010) 2.96
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Modulating F-actin organization induces organ growth by affecting the Hippo pathway. EMBO J (2011) 2.75
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Yorkie: the final destination of Hippo signaling. Trends Cell Biol (2010) 1.65
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Crucial role for Mst1 and Mst2 kinases in early embryonic development of the mouse. Mol Cell Biol (2009) 1.58
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Genetic control of size in Drosophila. Philos Trans R Soc Lond B Biol Sci (2000) 1.55
Toll Receptor-Mediated Hippo Signaling Controls Innate Immunity in Drosophila. Cell (2016) 1.54
Hippo signaling regulates Yorkie nuclear localization and activity through 14-3-3 dependent and independent mechanisms. Dev Biol (2009) 1.54
The hippo pathway promotes Notch signaling in regulation of cell differentiation, proliferation, and oocyte polarity. PLoS One (2008) 1.53
Lats2 is a negative regulator of myocyte size in the heart. Circ Res (2008) 1.53
Mst1/2 signalling to Yap: gatekeeper for liver size and tumour development. Br J Cancer (2010) 1.53
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The Hippo pathway regulates apical-domain size independently of its growth-control function. J Cell Sci (2009) 1.50
Differential proliferation rates generate patterns of mechanical tension that orient tissue growth. EMBO J (2013) 1.49
Fat/Dachsous Signaling Promotes Drosophila Wing Growth by Regulating the Conformational State of the NDR Kinase Warts. Dev Cell (2015) 1.48
Pax3 and hippo signaling coordinate melanocyte gene expression in neural crest. Cell Rep (2014) 1.46
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Lats2 kinase potentiates Snail1 activity by promoting nuclear retention upon phosphorylation. EMBO J (2011) 1.26
Growth control by committee: intercellular junctions, cell polarity, and the cytoskeleton regulate Hippo signaling. Dev Cell (2012) 1.26
A mosaic genetic screen for Drosophila neoplastic tumor suppressor genes based on defective pupation. Genetics (2007) 1.24
Drosophila Mob family proteins interact with the related tricornered (Trc) and warts (Wts) kinases. Mol Biol Cell (2005) 1.24
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Initiation of cytokinesis is controlled through multiple modes of regulation of the Sid2p-Mob1p kinase complex. Mol Cell Biol (2004) 1.21
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The Hippo tumor-suppressor pathway regulates apical-domain size in parallel to tissue growth. J Cell Sci (2009) 1.20
Drosophila C-terminal Src kinase negatively regulates organ growth and cell proliferation through inhibition of the Src, Jun N-terminal kinase, and STAT pathways. Mol Cell Biol (2004) 1.18
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The STE20/germinal center kinase POD6 interacts with the NDR kinase COT1 and is involved in polar tip extension in Neurospora crassa. Mol Biol Cell (2006) 1.17
The cell adhesion molecule echinoid functions as a tumor suppressor and upstream regulator of the Hippo signaling pathway. Dev Cell (2012) 1.16
Warts is required for PI3K-regulated growth arrest, autophagy, and autophagic cell death in Drosophila. Curr Biol (2008) 1.16
MicroRNA-31 regulated by the extracellular regulated kinase is involved in vascular smooth muscle cell growth via large tumor suppressor homolog 2. J Biol Chem (2011) 1.16
Loss of the Drosophila cell polarity regulator Scribbled promotes epithelial tissue overgrowth and cooperation with oncogenic Ras-Raf through impaired Hippo pathway signaling. BMC Dev Biol (2011) 1.15
Integration of intercellular signaling through the Hippo pathway. Semin Cell Dev Biol (2012) 1.14
Hippo signaling at a glance. J Cell Sci (2010) 1.14
Defining the protein-protein interaction network of the human hippo pathway. Mol Cell Proteomics (2013) 1.14
Differing Src signaling levels have distinct outcomes in Drosophila. Cancer Res (2007) 1.13
Fission yeast Mor2/Cps12, a protein similar to Drosophila Furry, is essential for cell morphogenesis and its mutation induces Wee1-dependent G(2) delay. EMBO J (2002) 1.10
Feedback from rhodopsin controls rhodopsin exclusion in Drosophila photoreceptors. Nature (2011) 1.10
Polycomb group-dependent Cyclin A repression in Drosophila. Genes Dev (2006) 1.10
The Hippo pathway polarizes the actin cytoskeleton during collective migration of Drosophila border cells. J Cell Biol (2013) 1.10
Regulation and functions of mammalian LATS/NDR kinases: looking beyond canonical Hippo signalling. Cell Biosci (2013) 1.09
Quit your YAPing: a new target for cancer therapy. Genes Dev (2012) 1.08
Transcriptional analysis of pluripotency reveals the Hippo pathway as a barrier to reprogramming. Hum Mol Genet (2012) 1.07
Wbp2 cooperates with Yorkie to drive tissue growth downstream of the Salvador-Warts-Hippo pathway. Cell Death Differ (2011) 1.06
A systematic screen for tube morphogenesis and branching genes in the Drosophila tracheal system. PLoS Genet (2011) 1.06
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Two NDR kinase-MOB complexes function as distinct modules during septum formation and tip extension in Neurospora crassa. Mol Microbiol (2009) 1.05
A Drosophila model of multiple endocrine neoplasia type 2. Genetics (2005) 1.03
Binary fate decisions in differentiating neurons. Curr Opin Neurobiol (2010) 1.02
The Biomolecular Interaction Network Database and related tools 2005 update. Nucleic Acids Res (2005) 12.94
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