Molecular physiology of the WNK kinases.

Mutations in kelch-like 3 and cullin 3 cause hypertension and electrolyte abnormalities. Nature (2012) 4.26

A comprehensive guide to the ROMK potassium channel: form and function in health and disease. Am J Physiol Renal Physiol (2009) 2.51

Role of the WNK-activated SPAK kinase in regulating blood pressure. EMBO Mol Med (2010) 2.36

Angiotensin II signaling increases activity of the renal Na-Cl cotransporter through a WNK4-SPAK-dependent pathway. Proc Natl Acad Sci U S A (2009) 2.30

Expression and phosphorylation of the Na+-Cl- cotransporter NCC in vivo is regulated by dietary salt, potassium, and SGK1. Am J Physiol Renal Physiol (2009) 2.03

Chloride channels: often enigmatic, rarely predictable. Annu Rev Physiol (2010) 1.94

WNK4 enhances the degradation of NCC through a sortilin-mediated lysosomal pathway. J Am Soc Nephrol (2009) 1.87

Renal and brain isoforms of WNK3 have opposite effects on NCCT expression. J Am Soc Nephrol (2009) 1.74

Mineralocorticoid receptor phosphorylation regulates ligand binding and renal response to volume depletion and hyperkalemia. Cell Metab (2013) 1.72

Molecular mechanism of pancreatic and salivary gland fluid and HCO3 secretion. Physiol Rev (2012) 1.71

Aldosterone mediates activation of the thiazide-sensitive Na-Cl cotransporter through an SGK1 and WNK4 signaling pathway. J Clin Invest (2009) 1.59

The thiazide-sensitive Na+-Cl- cotransporter: molecular biology, functional properties, and regulation by WNKs. Am J Physiol Renal Physiol (2009) 1.58

Kelch-like 3 and Cullin 3 regulate electrolyte homeostasis via ubiquitination and degradation of WNK4. Proc Natl Acad Sci U S A (2013) 1.56

WNK4 diverts the thiazide-sensitive NaCl cotransporter to the lysosome and stimulates AP-3 interaction. J Biol Chem (2009) 1.44

Regulated sodium transport in the renal connecting tubule (CNT) via the epithelial sodium channel (ENaC). Pflugers Arch (2009) 1.44

Molecular components of signal amplification in olfactory sensory cilia. Proc Natl Acad Sci U S A (2010) 1.39

Regulation of potassium (K) handling in the renal collecting duct. Pflugers Arch (2008) 1.39

Regulation of brain tumor dispersal by NKCC1 through a novel role in focal adhesion regulation. PLoS Biol (2012) 1.29

Phosphoregulation of the Na-K-2Cl and K-Cl cotransporters by the WNK kinases. Biochim Biophys Acta (2010) 1.22

Role of epithelial sodium channels and their regulators in hypertension. J Biol Chem (2010) 1.20

IRBIT governs epithelial secretion in mice by antagonizing the WNK/SPAK kinase pathway. J Clin Invest (2011) 1.18

Molecular physiology of SPAK and OSR1: two Ste20-related protein kinases regulating ion transport. Physiol Rev (2012) 1.18

LINGO-1 interacts with WNK1 to regulate nogo-induced inhibition of neurite extension. J Biol Chem (2009) 1.14

Slc26a9 is inhibited by the R-region of the cystic fibrosis transmembrane conductance regulator via the STAS domain. J Biol Chem (2009) 1.08

Transcriptome analysis of rice root responses to potassium deficiency. BMC Plant Biol (2012) 1.07

The inextricable role of the kidney in hypertension. J Clin Invest (2014) 1.05

WNK2 kinase is a novel regulator of essential neuronal cation-chloride cotransporters. J Biol Chem (2011) 1.04

The WNK-regulated SPAK/OSR1 kinases directly phosphorylate and inhibit the K+-Cl- co-transporters. Biochem J (2014) 1.02

Regulation of Potassium Homeostasis. Clin J Am Soc Nephrol (2014) 1.01

A new methodology for quantification of alternatively spliced exons reveals a highly tissue-specific expression pattern of WNK1 isoforms. PLoS One (2012) 1.00

Genetics of hypertension: from experimental animals to humans. Biochim Biophys Acta (2009) 1.00

Src family protein tyrosine kinase (PTK) modulates the effect of SGK1 and WNK4 on ROMK channels. Proc Natl Acad Sci U S A (2009) 0.99

Sodium balance is not just a renal affair. Curr Opin Nephrol Hypertens (2014) 0.99

Angiotensin II signaling via protein kinase C phosphorylates Kelch-like 3, preventing WNK4 degradation. Proc Natl Acad Sci U S A (2014) 0.95

Inhibition of K+ secretion in the distal nephron in nephrotic syndrome: possible role of albuminuria. J Physiol (2011) 0.95

Characterisation of the Cullin-3 mutation that causes a severe form of familial hypertension and hyperkalaemia. EMBO Mol Med (2015) 0.94

Dissecting complex traits: recent advances in hypertension genomics. Genome Med (2009) 0.93

Sensors, transducers, and effectors that regulate cell size and shape. J Biol Chem (2008) 0.93

Protein phosphatase 1 modulates the inhibitory effect of With-no-Lysine kinase 4 on ROMK channels. Am J Physiol Renal Physiol (2012) 0.93

With-No-Lysine Kinase 3 (WNK3) stimulates glioma invasion by regulating cell volume. Am J Physiol Cell Physiol (2011) 0.92

Structural and biochemical characterization of the KLHL3-WNK kinase interaction important in blood pressure regulation. Biochem J (2014) 0.90

Cell-type specific distribution of chloride transporters in the rat suprachiasmatic nucleus. Neuroscience (2009) 0.90

Inhibition of WNK3 Kinase Signaling Reduces Brain Damage and Accelerates Neurological Recovery After Stroke. Stroke (2015) 0.89

Direct activation of ENaC by angiotensin II: recent advances and new insights. Curr Hypertens Rep (2013) 0.89

WNK1 promotes PIP₂ synthesis to coordinate growth factor and GPCR-Gq signaling. Curr Biol (2011) 0.88

ASK3 responds to osmotic stress and regulates blood pressure by suppressing WNK1-SPAK/OSR1 signaling in the kidney. Nat Commun (2012) 0.87

Serine-threonine kinase with-no-lysine 4 (WNK4) controls blood pressure via transient receptor potential canonical 3 (TRPC3) in the vasculature. Proc Natl Acad Sci U S A (2011) 0.87

WNK4 kinase stimulates caveola-mediated endocytosis of TRPV5 amplifying the dynamic range of regulation of the channel by protein kinase C. J Biol Chem (2010) 0.86

Differential regulation of a CLC anion channel by SPAK kinase ortholog-mediated multisite phosphorylation. Am J Physiol Cell Physiol (2012) 0.85

WNK4 inhibits NCC protein expression through MAPK ERK1/2 signaling pathway. Am J Physiol Renal Physiol (2011) 0.85

Nedd4-2 and the regulation of epithelial sodium transport. Front Physiol (2012) 0.85

C. elegans STK39/SPAK ortholog-mediated inhibition of ClC anion channel activity is regulated by WNK-independent ERK kinase signaling. Am J Physiol Cell Physiol (2010) 0.85

Participation of the Cl-/HCO(3)- exchangers SLC26A3 and SLC26A6, the Cl- channel CFTR, and the regulatory factor SLC9A3R1 in mouse sperm capacitation. Biol Reprod (2012) 0.84

Regulation of the Na+-Cl- cotransporter by dietary NaCl: a role for WNKs, SPAK, OSR1, and aldosterone. Kidney Int (2008) 0.84

Limitations of Current GABA Agonists in Neonatal Seizures: Toward GABA Modulation Via the Targeting of Neuronal Cl(-) Transport. Front Neurol (2013) 0.84

Ion and solute transport by Prestin in Drosophila and Anopheles. J Insect Physiol (2012) 0.83

Influence of WNK3 on intracellular chloride concentration and volume regulation in HEK293 cells. Pflugers Arch (2012) 0.83

Regulation and function of potassium channels in aldosterone-sensitive distal nephron. Curr Opin Nephrol Hypertens (2010) 0.83

WNK4 inhibits Ca(2+)-activated big-conductance potassium channels (BK) via mitogen-activated protein kinase-dependent pathway. Biochim Biophys Acta (2013) 0.82

Src-family protein tyrosine kinase phosphorylates WNK4 and modulates its inhibitory effect on KCNJ1 (ROMK). Proc Natl Acad Sci U S A (2015) 0.81

Lack of association between polymorphisms in STK39, a putative thiazide response gene, and blood pressure response to hydrochlorothiazide. Pharmacogenet Genomics (2010) 0.81

Critical role of the SPAK protein kinase CCT domain in controlling blood pressure. Hum Mol Genet (2015) 0.81

Genetics of hypertension: discoveries from the bench to human populations. Am J Physiol Renal Physiol (2013) 0.80

Antagonistic regulation of cystic fibrosis transmembrane conductance regulator cell surface expression by protein kinases WNK4 and spleen tyrosine kinase. Mol Cell Biol (2011) 0.80

Disruption of AtWNK8 enhances tolerance of Arabidopsis to salt and osmotic stresses via modulating proline content and activities of catalase and peroxidase. Int J Mol Sci (2013) 0.80

Chemical crosslinking studies with the mouse Kcc1 K-Cl cotransporter. Blood Cells Mol Dis (2009) 0.80

Renal proteinase-activated receptor 2, a new actor in the control of blood pressure and plasma potassium level. J Biol Chem (2013) 0.80

MicroRNA-194 (miR-194) regulates ROMK channel activity by targeting intersectin 1. Am J Physiol Renal Physiol (2013) 0.79

Kinase-KCC2 coupling: Cl- rheostasis, disease susceptibility, therapeutic target. J Neurophysiol (2015) 0.78

Maintenance and regulation of extracellular volume and the ion environment in Drosophila larval nerves. Glia (2011) 0.78

Deletion of the WNK3-SPAK kinase complex in mice improves radiographic and clinical outcomes in malignant cerebral edema after ischemic stroke. J Cereb Blood Flow Metab (2016) 0.78

Decrease in dietary K intake stimulates the generation of superoxide anions in the kidney and inhibits K secretory channels in the CCD. Am J Physiol Renal Physiol (2010) 0.77

Protein kinase WNK1 promotes cell surface expression of glucose transporter GLUT1 by regulating a Tre-2/USP6-BUB2-Cdc16 domain family member 4 (TBC1D4)-Rab8A complex. J Biol Chem (2010) 0.77

Epigenetic Modifications in Essential Hypertension. Int J Mol Sci (2016) 0.77

Regulatory Crosstalk by Protein Kinases on CFTR Trafficking and Activity. Front Chem (2016) 0.77

WNKs in Wnt/β-catenin signaling. Cell Cycle (2013) 0.77

Control of electrolyte balance through ubiquitination. Proc Natl Acad Sci U S A (2013) 0.76

Murine cutaneous responses to the rocky mountain spotted fever vector, Dermacentor andersoni, feeding. Front Microbiol (2014) 0.76

Expanding Spectrum of Sodium Potassium Chloride Co-transporters in the Pathophysiology of Diseases. Curr Neuropharmacol (2015) 0.76

Hypertension: the missing WNKs. Am J Physiol Renal Physiol (2016) 0.76

Lack of family-based association between common variations in WNK1 and blood pressure level. Med Sci Monit (2014) 0.75

Proteomic and phosphoproteomic analysis of renal cortex in a salt-load rat model of advanced kidney damage. Sci Rep (2016) 0.75

Putting the pieces together: a crystal clear window into CLC anion channel regulation. Channels (Austin) (2011) 0.75

Regulated endocytosis of NCC. Am J Physiol Renal Physiol (2010) 0.75

Basolateral Kir4.1 activity in the distal convoluted tubule regulates K secretion by determining NaCl cotransporter activity. Curr Opin Nephrol Hypertens (2016) 0.75

Beyond translation: the renal phosphate census. Focus on "Large-scale phosphoproteomic analysis of membrane proteins in renal proximal and distal tubule". Am J Physiol Cell Physiol (2011) 0.75

Endoplasmic reticulum-associated degradation of the renal potassium channel, ROMK, leads to type II Bartter syndrome. J Biol Chem (2017) 0.75

Association between Cullin-3 Single-Nucleotide Polymorphism rs17479770 and Essential Hypertension in the Male Chinese Han Population. Dis Markers (2017) 0.75

Genetic diagnosis by whole exome capture and massively parallel DNA sequencing. Proc Natl Acad Sci U S A (2009) 15.09

De novo mutations revealed by whole-exome sequencing are strongly associated with autism. Nature (2012) 13.61

High bone density due to a mutation in LDL-receptor-related protein 5. N Engl J Med (2002) 11.28

Multiple recurrent de novo CNVs, including duplications of the 7q11.23 Williams syndrome region, are strongly associated with autism. Neuron (2011) 10.61

Sequence variants in SLITRK1 are associated with Tourette's syndrome. Science (2005) 8.20

Nonvalidation of reported genetic risk factors for acute coronary syndrome in a large-scale replication study. JAMA (2007) 7.12

Exome sequencing identifies recurrent somatic RAC1 mutations in melanoma. Nat Genet (2012) 7.00

Apolipoprotein C3 gene variants in nonalcoholic fatty liver disease. N Engl J Med (2010) 6.45

Whole-exome sequencing identifies recessive WDR62 mutations in severe brain malformations. Nature (2010) 6.26

Molecular cytogenetic analysis and resequencing of contactin associated protein-like 2 in autism spectrum disorders. Am J Hum Genet (2008) 5.44

K+ channel mutations in adrenal aldosterone-producing adenomas and hereditary hypertension. Science (2011) 5.40

De novo mutations in histone-modifying genes in congenital heart disease. Nature (2013) 5.15

LRP6 mutation in a family with early coronary disease and metabolic risk factors. Science (2007) 4.27

Mutations in kelch-like 3 and cullin 3 cause hypertension and electrolyte abnormalities. Nature (2012) 4.26

WNK4 regulates the balance between renal NaCl reabsorption and K+ secretion. Nat Genet (2003) 4.08

Wnk4 controls blood pressure and potassium homeostasis via regulation of mass and activity of the distal convoluted tubule. Nat Genet (2006) 3.57

Molecular pathogenesis of inherited hypertension with hyperkalemia: the Na-Cl cotransporter is inhibited by wild-type but not mutant WNK4. Proc Natl Acad Sci U S A (2003) 3.48

Genomic analysis of non-NF2 meningiomas reveals mutations in TRAF7, KLF4, AKT1, and SMO. Science (2013) 3.45

Engineered SIRPα variants as immunotherapeutic adjuvants to anticancer antibodies. Science (2013) 3.25

Genome-wide association study identifies susceptibility loci for IgA nephropathy. Nat Genet (2011) 3.15

The Centers for Mendelian Genomics: a new large-scale initiative to identify the genes underlying rare Mendelian conditions. Am J Med Genet A (2012) 3.12

L-histidine decarboxylase and Tourette's syndrome. N Engl J Med (2010) 2.92

Recessive mutations in DGKE cause atypical hemolytic-uremic syndrome. Nat Genet (2013) 2.91

Activation and allosteric modulation of a muscarinic acetylcholine receptor. Nature (2013) 2.49

A novel form of human mendelian hypertension featuring nonglucocorticoid-remediable aldosteronism. J Clin Endocrinol Metab (2008) 2.48

Seizures, sensorineural deafness, ataxia, mental retardation, and electrolyte imbalance (SeSAME syndrome) caused by mutations in KCNJ10. Proc Natl Acad Sci U S A (2009) 2.41

Skint1, the prototype of a newly identified immunoglobulin superfamily gene cluster, positively selects epidermal gammadelta T cells. Nat Genet (2008) 2.31

Angiotensin II signaling increases activity of the renal Na-Cl cotransporter through a WNK4-SPAK-dependent pathway. Proc Natl Acad Sci U S A (2009) 2.30

Mitotic recombination in patients with ichthyosis causes reversion of dominant mutations in KRT10. Science (2010) 2.21

Roles of the cation-chloride cotransporters in neurological disease. Nat Clin Pract Neurol (2008) 2.19

Individual genomes on the horizon. N Engl J Med (2010) 2.09

Somatic and germline CACNA1D calcium channel mutations in aldosterone-producing adenomas and primary aldosteronism. Nat Genet (2013) 2.09

Exploiting a natural conformational switch to engineer an interleukin-2 'superkine'. Nature (2012) 2.08

Evaluating potential for whole-genome studies in Kosrae, an isolated population in Micronesia. Nat Genet (2006) 2.07

Landscape of somatic single-nucleotide and copy-number mutations in uterine serous carcinoma. Proc Natl Acad Sci U S A (2013) 2.02

Genome-wide association studies in an isolated founder population from the Pacific Island of Kosrae. PLoS Genet (2009) 2.02

Mutations in SEC63 cause autosomal dominant polycystic liver disease. Nat Genet (2004) 1.96

WNK3 kinase is a positive regulator of NKCC2 and NCC, renal cation-Cl- cotransporters required for normal blood pressure homeostasis. Proc Natl Acad Sci U S A (2005) 1.96

A cluster of metabolic defects caused by mutation in a mitochondrial tRNA. Science (2004) 1.95

Sites of regulated phosphorylation that control K-Cl cotransporter activity. Cell (2009) 1.93

Susceptibility loci for intracranial aneurysm in European and Japanese populations. Nat Genet (2008) 1.90

Recessive LAMC3 mutations cause malformations of occipital cortical development. Nat Genet (2011) 1.89

Regulation of NKCC2 by a chloride-sensing mechanism involving the WNK3 and SPAK kinases. Proc Natl Acad Sci U S A (2008) 1.88

Disruption of contactin 4 (CNTN4) results in developmental delay and other features of 3p deletion syndrome. Am J Hum Genet (2004) 1.87

Genome-wide association study of intracranial aneurysm identifies three new risk loci. Nat Genet (2010) 1.86

WNK1, a kinase mutated in inherited hypertension with hyperkalemia, localizes to diverse Cl- -transporting epithelia. Proc Natl Acad Sci U S A (2003) 1.82

WNK3 modulates transport of Cl- in and out of cells: implications for control of cell volume and neuronal excitability. Proc Natl Acad Sci U S A (2005) 1.76

Aberrant IgA1 glycosylation is inherited in familial and sporadic IgA nephropathy. J Am Soc Nephrol (2008) 1.76

Hypertension with or without adrenal hyperplasia due to different inherited mutations in the potassium channel KCNJ5. Proc Natl Acad Sci U S A (2012) 1.74

ADCK4 mutations promote steroid-resistant nephrotic syndrome through CoQ10 biosynthesis disruption. J Clin Invest (2013) 1.74

Mineralocorticoid receptor phosphorylation regulates ligand binding and renal response to volume depletion and hyperkalemia. Cell Metab (2013) 1.72

WNK4 regulates apical and basolateral Cl- flux in extrarenal epithelia. Proc Natl Acad Sci U S A (2004) 1.71

Rare copy number variations in congenital heart disease patients identify unique genes in left-right patterning. Proc Natl Acad Sci U S A (2011) 1.71

Geographic differences in genetic susceptibility to IgA nephropathy: GWAS replication study and geospatial risk analysis. PLoS Genet (2012) 1.69

KANK deficiency leads to podocyte dysfunction and nephrotic syndrome. J Clin Invest (2015) 1.69

Paracellular Cl- permeability is regulated by WNK4 kinase: insight into normal physiology and hypertension. Proc Natl Acad Sci U S A (2004) 1.68

An SGK1 site in WNK4 regulates Na+ channel and K+ channel activity and has implications for aldosterone signaling and K+ homeostasis. Proc Natl Acad Sci U S A (2007) 1.65

Autosomal dominant pseudohypoaldosteronism type 1: mechanisms, evidence for neonatal lethality, and phenotypic expression in adults. J Am Soc Nephrol (2006) 1.63

Copy-number disorders are a common cause of congenital kidney malformations. Am J Hum Genet (2012) 1.63

KRIT1, a gene mutated in cerebral cavernous malformation, encodes a microtubule-associated protein. Proc Natl Acad Sci U S A (2002) 1.57

Kelch-like 3 and Cullin 3 regulate electrolyte homeostasis via ubiquitination and degradation of WNK4. Proc Natl Acad Sci U S A (2013) 1.56

A translocation causing increased alpha-klotho level results in hypophosphatemic rickets and hyperparathyroidism. Proc Natl Acad Sci U S A (2008) 1.56

The B1-subunit of the H(+) ATPase is required for maximal urinary acidification. Proc Natl Acad Sci U S A (2005) 1.51

Whole-exome sequencing reveals somatic mutations in HRAS and KRAS, which cause nevus sebaceus. J Invest Dermatol (2012) 1.50

Susceptibility loci for murine HIV-associated nephropathy encode trans-regulators of podocyte gene expression. J Clin Invest (2009) 1.49

WNK4 regulates activity of the epithelial Na+ channel in vitro and in vivo. Proc Natl Acad Sci U S A (2007) 1.46

Cytokine therapy reverses NK cell anergy in MHC-deficient tumors. J Clin Invest (2014) 1.45

Finding genetic contributions to sporadic disease: a recessive locus at 12q24 commonly contributes to patent ductus arteriosus. Proc Natl Acad Sci U S A (2002) 1.42

Mapping a locus for susceptibility to HIV-1-associated nephropathy to mouse chromosome 3. Proc Natl Acad Sci U S A (2004) 1.38

WNK3 bypasses the tonicity requirement for K-Cl cotransporter activation via a phosphatase-dependent pathway. Proc Natl Acad Sci U S A (2006) 1.33

Regulation of the expression of the Cl-/anion exchanger pendrin in mouse kidney by acid-base status. Kidney Int (2002) 1.32

Disruption of Contactin 4 (CNTN4) results in developmental delay and other features of 3p deletion syndrome. Am J Hum Genet (2008) 1.31

Regulation of diverse ion transport pathways by WNK4 kinase: a novel molecular switch. Trends Endocrinol Metab (2005) 1.31

Comprehensive re-sequencing of adrenal aldosterone producing lesions reveal three somatic mutations near the KCNJ5 potassium channel selectivity filter. PLoS One (2012) 1.30

Skint-1 is a highly specific, unique selecting component for epidermal T cells. Proc Natl Acad Sci U S A (2011) 1.30

Identification of somatic mutations in parathyroid tumors using whole-exome sequencing. J Clin Endocrinol Metab (2012) 1.26

KRIT1/cerebral cavernous malformation 1 protein localizes to vascular endothelium, astrocytes, and pyramidal cells of the adult human cerebral cortex. Neurosurgery (2004) 1.24

Wild-type LRP6 inhibits, whereas atherosclerosis-linked LRP6R611C increases PDGF-dependent vascular smooth muscle cell proliferation. Proc Natl Acad Sci U S A (2011) 1.24

WNK protein kinases modulate cellular Cl- flux by altering the phosphorylation state of the Na-K-Cl and K-Cl cotransporters. Physiology (Bethesda) (2006) 1.22

Adenosine metabolism and murine strain-specific IL-4-induced inflammation, emphysema, and fibrosis. J Clin Invest (2006) 1.22

Phosphoregulation of the Na-K-2Cl and K-Cl cotransporters by the WNK kinases. Biochim Biophys Acta (2010) 1.22

Decreased ENaC expression compensates the increased NCC activity following inactivation of the kidney-specific isoform of WNK1 and prevents hypertension. Proc Natl Acad Sci U S A (2010) 1.18

Syndromic patent ductus arteriosus: evidence for haploinsufficient TFAP2B mutations and identification of a linked sleep disorder. Proc Natl Acad Sci U S A (2005) 1.17

Low density lipoprotein (LDL) receptor-related protein 6 (LRP6) regulates body fat and glucose homeostasis by modulating nutrient sensing pathways and mitochondrial energy expenditure. J Biol Chem (2012) 1.13

On optimal pooling designs to identify rare variants through massive resequencing. Genet Epidemiol (2011) 1.12

Molecular genetic analysis of two large kindreds with intracranial aneurysms demonstrates linkage to 11q24-25 and 14q23-31. Stroke (2006) 1.12

Recessive loss of function of the neuronal ubiquitin hydrolase UCHL1 leads to early-onset progressive neurodegeneration. Proc Natl Acad Sci U S A (2013) 1.09

Common variant near the endothelin receptor type A (EDNRA) gene is associated with intracranial aneurysm risk. Proc Natl Acad Sci U S A (2011) 1.08

NordicDB: a Nordic pool and portal for genome-wide control data. Eur J Hum Genet (2010) 1.07

WNK3, a kinase related to genes mutated in hereditary hypertension with hyperkalaemia, regulates the K+ channel ROMK1 (Kir1.1). J Physiol (2005) 1.07

Rare mutations in the human Na-K-Cl cotransporter (NKCC2) associated with lower blood pressure exhibit impaired processing and transport function. Am J Physiol Renal Physiol (2011) 1.06

Mapping a Mendelian form of intracranial aneurysm to 1p34.3-p36.13. Am J Hum Genet (2004) 1.05

Accelerated development of collapsing glomerulopathy in mice congenic for the HIVAN1 locus. Kidney Int (2008) 1.04

WNK2 kinase is a novel regulator of essential neuronal cation-chloride cotransporters. J Biol Chem (2011) 1.04

WNK kinases: molecular regulators of integrated epithelial ion transport. Curr Opin Nephrol Hypertens (2004) 1.04

AMP-activated protein kinase (AMPK) activation and glycogen synthase kinase-3β (GSK-3β) inhibition induce Ca2+-independent deposition of tight junction components at the plasma membrane. J Biol Chem (2011) 1.03

COL4A1 mutation in preterm intraventricular hemorrhage. J Pediatr (2009) 1.01

Epigenetic abnormalities associated with a chromosome 18(q21-q22) inversion and a Gilles de la Tourette syndrome phenotype. Proc Natl Acad Sci U S A (2003) 1.01