Published in J Biol Chem on April 10, 2009
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Crystal structure of the kinase domain of WNK1, a kinase that causes a hereditary form of hypertension. Structure (2004) 1.82
WNK1 activates ERK5 by an MEKK2/3-dependent mechanism. J Biol Chem (2003) 1.80
Epigenome scans and cancer genome sequencing converge on WNK2, a kinase-independent suppressor of cell growth. Proc Natl Acad Sci U S A (2007) 1.78
Structure and axon outgrowth inhibitor binding of the Nogo-66 receptor and related proteins. EMBO J (2003) 1.78
WNK1 activates SGK1 to regulate the epithelial sodium channel. Proc Natl Acad Sci U S A (2005) 1.76
WNK kinases influence TRPV4 channel function and localization. Am J Physiol Renal Physiol (2006) 1.74
The thiazide-sensitive Na-Cl cotransporter is regulated by a WNK kinase signaling complex. J Clin Invest (2007) 1.70
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WNK1 kinase isoform switch regulates renal potassium excretion. Proc Natl Acad Sci U S A (2006) 1.65
Mutations in the nervous system--specific HSN2 exon of WNK1 cause hereditary sensory neuropathy type II. J Clin Invest (2008) 1.61
Inhibition of the leucine-rich repeat protein LINGO-1 enhances survival, structure, and function of dopaminergic neurons in Parkinson's disease models. Proc Natl Acad Sci U S A (2007) 1.58
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LINGO-1 antagonist promotes functional recovery and axonal sprouting after spinal cord injury. Mol Cell Neurosci (2006) 1.28
WNK protein kinases modulate cellular Cl- flux by altering the phosphorylation state of the Na-K-Cl and K-Cl cotransporters. Physiology (Bethesda) (2006) 1.22
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Interaction of SH2-Bbeta with RET is involved in signaling of GDNF-induced neurite outgrowth. J Cell Sci (2006) 1.06
WNK kinases and the control of blood pressure. Pharmacol Ther (2005) 1.04
Cardiovascular expression of the mouse WNK1 gene during development and adulthood revealed by a BAC reporter assay. Am J Pathol (2006) 1.03
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Down-regulation of WNK1 protein kinase in neural progenitor cells suppresses cell proliferation and migration. J Neurochem (2006) 0.99
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Glial inhibition of nerve regeneration in the mature mammalian CNS. Glia (2000) 0.98
Protein kinase WNK3 increases cell survival in a caspase-3-dependent pathway. Oncogene (2006) 0.95
The role of Kalirin9 in p75/nogo receptor-mediated RhoA activation in cerebellar granule neurons. J Biol Chem (2008) 0.93
MKLP1 requires specific domains for its dendritic targeting. J Cell Sci (2006) 0.91
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A draft sequence for the genome of the domesticated silkworm (Bombyx mori). Science (2004) 6.62
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Rapid and efficient gene modification in rice and Brachypodium using TALENs. Mol Plant (2013) 1.56
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Myostatin induces cyclin D1 degradation to cause cell cycle arrest through a phosphatidylinositol 3-kinase/AKT/GSK-3 beta pathway and is antagonized by insulin-like growth factor 1. J Biol Chem (2006) 1.55
MicroRNA-21 targets LRRFIP1 and contributes to VM-26 resistance in glioblastoma multiforme. Brain Res (2009) 1.55
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Association of high iodine intake with the T1799A BRAF mutation in papillary thyroid cancer. J Clin Endocrinol Metab (2009) 1.55
Tight junction-associated MARVEL proteins marveld3, tricellulin, and occludin have distinct but overlapping functions. Mol Biol Cell (2010) 1.51
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A common haplotype of the dopamine transporter gene associated with attention-deficit/hyperactivity disorder and interacting with maternal use of alcohol during pregnancy. Arch Gen Psychiatry (2006) 1.50