Published in Nucleic Acids Res on October 25, 2007
Inactivation of the orphan nuclear receptor TR3/Nur77 inhibits pancreatic cancer cell and tumor growth. Cancer Res (2010) 1.37
The HTLV-1-encoded protein HBZ directly inhibits the acetyl transferase activity of p300/CBP. Nucleic Acids Res (2012) 0.83
A feedback regulatory loop between methyltransferase PRMT1 and orphan receptor TR3. Nucleic Acids Res (2008) 0.81
6-Mercaptopurine attenuates tumor necrosis factor-α production in microglia through Nur77-mediated transrepression and PI3K/Akt/mTOR signaling-mediated translational regulation. J Neuroinflammation (2016) 0.79
Nur77 suppresses hepatocellular carcinoma via switching glucose metabolism toward gluconeogenesis through attenuating phosphoenolpyruvate carboxykinase sumoylation. Nat Commun (2017) 0.75
Activation of p53 sequence-specific DNA binding by acetylation of the p53 C-terminal domain. Cell (1997) 16.79
The transcriptional coactivators p300 and CBP are histone acetyltransferases. Cell (1996) 16.57
The CBP co-activator is a histone acetyltransferase. Nature (1997) 10.91
A p300/CBP-associated factor that competes with the adenoviral oncoprotein E1A. Nature (1996) 10.81
Histone acetylation and transcriptional regulatory mechanisms. Genes Dev (1998) 10.16
Histone deacetylases and cancer: causes and therapies. Nat Rev Cancer (2001) 9.12
Molecular cloning and functional analysis of the adenovirus E1A-associated 300-kD protein (p300) reveals a protein with properties of a transcriptional adaptor. Genes Dev (1994) 8.92
Duration of nuclear NF-kappaB action regulated by reversible acetylation. Science (2001) 6.79
Cytochrome c release and apoptosis induced by mitochondrial targeting of nuclear orphan receptor TR3. Science (2000) 4.57
Adenoviral E1A-associated protein p300 as a functional homologue of the transcriptional co-activator CBP. Nature (1995) 4.49
Unique response pathways are established by allosteric interactions among nuclear hormone receptors. Cell (1995) 3.70
A viral mechanism for inhibition of p300 and PCAF acetyltransferase activity. Cell (1999) 3.36
Curcumin, a novel p300/CREB-binding protein-specific inhibitor of acetyltransferase, represses the acetylation of histone/nonhistone proteins and histone acetyltransferase-dependent chromatin transcription. J Biol Chem (2004) 3.13
Regulation of histone acetyltransferases p300 and PCAF by the bHLH protein twist and adenoviral oncoprotein E1A. Cell (1999) 2.90
Homeobox proteins as sequence-specific transcription factors. Cell (1988) 2.81
Histone deacetylase 2-mediated deacetylation of the glucocorticoid receptor enables NF-kappaB suppression. J Exp Med (2005) 2.72
Transcription. A growing coactivator network. Nature (1996) 2.71
A novel pathway for vitamin A signaling mediated by RXR heterodimerization with NGFI-B and NURR1. Genes Dev (1995) 2.50
The acetyltransferase activity of CBP stimulates transcription. EMBO J (1998) 2.45
The E6 protein of human papillomavirus type 16 binds to and inhibits co-activation by CBP and p300. EMBO J (1999) 2.44
Direct acetylation of the estrogen receptor alpha hinge region by p300 regulates transactivation and hormone sensitivity. J Biol Chem (2001) 2.16
Functional analysis of human herpesvirus 8-encoded viral interferon regulatory factor 1 and its association with cellular interferon regulatory factors and p300. J Virol (1999) 2.11
HDAC7, a thymus-specific class II histone deacetylase, regulates Nur77 transcription and TCR-mediated apoptosis. Immunity (2003) 2.10
Acetylation of beta-catenin by p300 regulates beta-catenin-Tcf4 interaction. Mol Cell Biol (2004) 1.95
Polyisoprenylated benzophenone, garcinol, a natural histone acetyltransferase inhibitor, represses chromatin transcription and alters global gene expression. J Biol Chem (2004) 1.90
Acetylation of androgen receptor enhances coactivator binding and promotes prostate cancer cell growth. Mol Cell Biol (2003) 1.89
Versatile molecular glue. Transcriptional control. Curr Biol (1996) 1.85
Akt phosphorylation of p300 at Ser-1834 is essential for its histone acetyltransferase and transcriptional activity. Mol Cell Biol (2005) 1.85
Inhibition of p300 histone acetyltransferase by viral interferon regulatory factor. Mol Cell Biol (2000) 1.61
Retracted Three unrelated viral transforming proteins (vIRF, EBNA2, and E1A) induce the MYC oncogene through the interferon-responsive PRF element by using different transcription coadaptors. Proc Natl Acad Sci U S A (1999) 1.52
A novel Rb- and p300-binding protein inhibits transactivation by MyoD. Mol Cell Biol (2000) 1.40
Histone deacetylase inhibitors: development of suberoylanilide hydroxamic acid (SAHA) for the treatment of cancers. Blood Cells Mol Dis (2001) 1.40
Activation of Nur77 by selected 1,1-Bis(3'-indolyl)-1-(p-substituted phenyl)methanes induces apoptosis through nuclear pathways. J Biol Chem (2005) 1.40
Cells degrade a novel inhibitor of differentiation with E1A-like properties upon exiting the cell cycle. Mol Cell Biol (2000) 1.35
Dual roles of Nur77 in selective regulation of apoptosis and cell cycle by TPA and ATRA in gastric cancer cells. Carcinogenesis (2002) 1.33
Modulation of retinoic acid sensitivity in lung cancer cells through dynamic balance of orphan receptors nur77 and COUP-TF and their heterodimerization. EMBO J (1997) 1.32
p53 mediates the negative regulation of MDM2 by orphan receptor TR3. EMBO J (2006) 1.30
The activation function-1 domain of Nur77/NR4A1 mediates trans-activation, cell specificity, and coactivator recruitment. J Biol Chem (2002) 1.25
The HOX homeodomain proteins block CBP histone acetyltransferase activity. Mol Cell Biol (2001) 1.24
Modifying chromatin and concepts of cancer. Curr Opin Genet Dev (1999) 1.20
Factor-specific modulation of CREB-binding protein acetyltransferase activity. Proc Natl Acad Sci U S A (1999) 1.12
Characterization of an E1A-CBP interaction defines a novel transcriptional adapter motif (TRAM) in CBP/p300. J Virol (1999) 1.11
Inhibition of trans-retinoic acid-resistant human breast cancer cell growth by retinoid X receptor-selective retinoids. Mol Cell Biol (1997) 1.09
Transcription factors. CREB takes CBP to tango. Nature (1994) 1.00
Attenuation of glucocorticoid signaling through targeted degradation of p300 via the 26S proteasome pathway. Mol Endocrinol (2002) 0.96
Inhibition of p300/CBP by early B-cell factor. Mol Cell Biol (2003) 0.94
The effect pathway of retinoic acid through regulation of retinoic acid receptor alpha in gastric cancer cells. World J Gastroenterol (2001) 0.90
Orphan receptor TR3 attenuates the p300-induced acetylation of retinoid X receptor-alpha. Mol Endocrinol (2007) 0.83
Retrieval of crystallographically-derived molecular geometry information. J Chem Inf Comput Sci (2004) 74.81
Enrichment of tomato fruit with health-promoting anthocyanins by expression of select transcription factors. Nat Biotechnol (2008) 3.04
SIFTS: Structure Integration with Function, Taxonomy and Sequences resource. Nucleic Acids Res (2012) 2.61
Cyclooxygenase-2-dependent regulation of E-cadherin: prostaglandin E(2) induces transcriptional repressors ZEB1 and snail in non-small cell lung cancer. Cancer Res (2006) 2.47
Facilitation of μ-opioid receptor activity by preventing δ-opioid receptor-mediated codegradation. Neuron (2011) 2.42
Phosphorylation of the transcription elongation factor Spt5 by yeast Bur1 kinase stimulates recruitment of the PAF complex. Mol Cell Biol (2009) 1.82
The orphan nuclear receptor Nur77 regulates LKB1 localization and activates AMPK. Nat Chem Biol (2012) 1.75
A multilevel adaptive finite element algorithm for bioluminescence tomography. Opt Express (2006) 1.71
Autocrine/paracrine prostaglandin E2 production by non-small cell lung cancer cells regulates matrix metalloproteinase-2 and CD44 in cyclooxygenase-2-dependent invasion. J Biol Chem (2002) 1.60
Cytosporone B is an agonist for nuclear orphan receptor Nur77. Nat Chem Biol (2008) 1.58
A role of RIP3-mediated macrophage necrosis in atherosclerosis development. Cell Rep (2013) 1.44
Snail promotes CXCR2 ligand-dependent tumor progression in non-small cell lung carcinoma. Clin Cancer Res (2009) 1.43
Tumor cyclooxygenase 2-dependent suppression of dendritic cell function. Clin Cancer Res (2003) 1.33
Biophysical mechanisms of MRI signal frequency contrast in multiple sclerosis. Proc Natl Acad Sci U S A (2012) 1.32
p53 mediates the negative regulation of MDM2 by orphan receptor TR3. EMBO J (2006) 1.30
IL-7 inhibits fibroblast TGF-beta production and signaling in pulmonary fibrosis. J Clin Invest (2002) 1.29
COX-2-dependent stabilization of survivin in non-small cell lung cancer. FASEB J (2003) 1.24
Beta3 subunits promote expression and nicotine-induced up-regulation of human nicotinic alpha6* nicotinic acetylcholine receptors expressed in transfected cell lines. Mol Pharmacol (2006) 1.23
Pigmented paraganglioma of the kidney: a case report. Diagn Pathol (2012) 1.18
Cyclooxygenase-2-dependent expression of angiogenic CXC chemokines ENA-78/CXC Ligand (CXCL) 5 and interleukin-8/CXCL8 in human non-small cell lung cancer. Cancer Res (2004) 1.17
Proinflammatory mediators upregulate snail in head and neck squamous cell carcinoma. Clin Cancer Res (2009) 1.17
Endothelial cells enhance prostate cancer metastasis via IL-6→androgen receptor→TGF-β→MMP-9 signals. Mol Cancer Ther (2013) 1.10
Novel hydroxycinnamoyl-coenzyme A quinate transferase genes from artichoke are involved in the synthesis of chlorogenic acid. Plant Physiol (2010) 1.09
Comparative genomics of parasitic silkworm microsporidia reveal an association between genome expansion and host adaptation. BMC Genomics (2013) 1.07
New therapy targeting differential androgen receptor signaling in prostate cancer stem/progenitor vs. non-stem/progenitor cells. J Mol Cell Biol (2012) 1.07
Prevention of β-amyloid induced toxicity in human iPS cell-derived neurons by inhibition of Cyclin-dependent kinases and associated cell cycle events. Stem Cell Res (2012) 1.05
Genetic analysis of the metabolome exemplified using a rice population. Proc Natl Acad Sci U S A (2013) 1.04
A unique pharmacophore for activation of the nuclear orphan receptor Nur77 in vivo and in vitro. Cancer Res (2010) 1.04
Biocidal efficacy, biofilm-controlling function, and controlled release effect of chloromelamine-based bioresponsive fibrous materials. Biomaterials (2006) 1.03
Overexpressing the glucocorticoid receptor in forebrain causes an aging-like neuroendocrine phenotype and mild cognitive dysfunction. J Neurosci (2007) 1.02
EGFR signaling is required for TGF-beta 1 mediated COX-2 induction in human bronchial epithelial cells. Am J Respir Cell Mol Biol (2007) 1.02
Voxel spread function method for correction of magnetic field inhomogeneity effects in quantitative gradient-echo-based MRI. Magn Reson Med (2012) 1.01
Nuclear accumulation of epidermal growth factor receptor and acceleration of G1/S stage by Epstein-Barr-encoded oncoprotein latent membrane protein 1. Exp Cell Res (2004) 1.01
A transcriptomic network underlies microstructural and physiological responses to cadmium in Populus x canescens. Plant Physiol (2013) 0.99
Myasthenia gravis and the tops and bottoms of AChRs: antigenic structure of the MIR and specific immunosuppression of EAMG using AChR cytoplasmic domains. Ann N Y Acad Sci (2008) 0.99
Diindolylmethane analogs bind NR4A1 and are NR4A1 antagonists in colon cancer cells. Mol Endocrinol (2014) 0.99
Targeting the unique methylation pattern of androgen receptor (AR) promoter in prostate stem/progenitor cells with 5-aza-2'-deoxycytidine (5-AZA) leads to suppressed prostate tumorigenesis. J Biol Chem (2012) 0.98
A novel integrated method for large-scale detection, identification, and quantification of widely targeted metabolites: application in the study of rice metabolomics. Mol Plant (2013) 0.98
The orphan receptor TR3 suppresses intestinal tumorigenesis in mice by downregulating Wnt signalling. Gut (2011) 0.97
Increased chemosensitivity via targeting testicular nuclear receptor 4 (TR4)-Oct4-interleukin 1 receptor antagonist (IL1Ra) axis in prostate cancer CD133+ stem/progenitor cells to battle prostate cancer. J Biol Chem (2013) 0.97
In vivo quantitative evaluation of brain tissue damage in multiple sclerosis using gradient echo plural contrast imaging technique. Neuroimage (2010) 0.97
Computer-aided diagnosis and quantification of cirrhotic livers based on morphological analysis and machine learning. Comput Math Methods Med (2013) 0.96
Identification of a novel Raf-1 pathway activator that inhibits gastrointestinal carcinoid cell growth. Mol Cancer Ther (2010) 0.96
RXRalpha acts as a carrier for TR3 nuclear export in a 9-cis retinoic acid-dependent manner in gastric cancer cells. J Cell Sci (2004) 0.95
Targeting androgen receptor in bone marrow mesenchymal stem cells leads to better transplantation therapy efficacy in liver cirrhosis. Hepatology (2013) 0.95
New insight into the antifibrotic effects of praziquantel on mice in infection with Schistosoma japonicum. PLoS One (2011) 0.95
Induction of apoptosis by TPA and VP-16 is through translocation of TR3. World J Gastroenterol (2002) 0.95
Overexpression of CCL-21/secondary lymphoid tissue chemokine in human dendritic cells augments chemotactic activities for lymphocytes and antigen presenting cells. Mol Cancer (2003) 0.94
RPB2 gene phylogeny in flowering plants, with particular emphasis on asterids. Mol Phylogenet Evol (2004) 0.94
Comparative study on polymer light-emitting devices based on blends of polyfluorene and 4,7-di-2-thienyl-2,1,3-benzothiadiazole with devices based on copolymer of the same composition. J Phys Chem B (2007) 0.93
N-fertilization has different effects on the growth, carbon and nitrogen physiology, and wood properties of slow- and fast-growing Populus species. J Exp Bot (2012) 0.93
Inhibition of retinal neovascularization by siRNA targeting VEGF(165). Mol Vis (2008) 0.93
Anthraquinone derivatives from Rumex plants and endophytic Aspergillus fumigatus and their effects on diabetic nephropathy. Bioorg Med Chem Lett (2013) 0.93
Thermal decomposition modes for four-coordinate ruthenium phosphonium alkylidene olefin metathesis catalysts. Chemistry (2008) 0.93
Orphan receptor TR3 is essential for the maintenance of stem-like properties in gastric cancer cells. Cancer Lett (2012) 0.92
Enhanced homing of mesenchymal stem cells to the ischemic myocardium by ultrasound-targeted microbubble destruction. Ultrasonics (2011) 0.91
Exome sequencing and digital PCR analyses reveal novel mutated genes related to the metastasis of pancreatic ductal adenocarcinoma. Cancer Biol Ther (2012) 0.91
The orphan receptor TR3 participates in angiotensin II-induced cardiac hypertrophy by controlling mTOR signalling. EMBO Mol Med (2012) 0.90
The role of ZEB1 in the inflammation-induced promotion of EMT in HNSCC. Otolaryngol Head Neck Surg (2010) 0.90
Structural and functional characterization of herpes simplex virus 1 immediate-early protein infected-cell protein 22. J Biochem (2006) 0.90
Premature aging with impaired oxidative stress defense in mice lacking TR4. Am J Physiol Endocrinol Metab (2011) 0.90
Amplified in breast cancer 1 enhances human cholangiocarcinoma growth and chemoresistance by simultaneous activation of Akt and Nrf2 pathways. Hepatology (2012) 0.90
Polymorphisms of base-excision repair genes hOGG1 326cys and XRCC1 280His increase hepatocellular carcinoma risk. Dig Dis Sci (2012) 0.90
Theoretical studies on the mechanisms and dynamics of OH radicals with CH(2)FCF(2)OCHF(2) and CH(2)FOCH(2)F. J Phys Chem A (2010) 0.89
Silver(I) complex formation with cysteine, penicillamine, and glutathione. Inorg Chem (2013) 0.89
Prevalences of and risk factors for biliary stones and gallbladder polyps in a large Chinese population. HPB (Oxford) (2012) 0.88
Asymmetric catalysis with chiral primary amine-based organocatalysts. Chem Commun (Camb) (2009) 0.88
Effects of ulinastatin and docataxel on breast tumor growth and expression of IL-6, IL-8, and TNF-α. J Exp Clin Cancer Res (2011) 0.88
Should patients with symptomatic Hashimoto's thyroiditis pursue surgery? J Surg Res (2011) 0.87
Regulation of the orphan receptor TR3 nuclear functions by c-Jun N terminal kinase phosphorylation. Endocrinology (2006) 0.87
A role of cell apoptosis in lipopolysaccharide (LPS)-induced nonlethal liver injury in D-galactosamine (D-GalN)-sensitized rats. Dig Dis Sci (2007) 0.87
The application of loop-mediated isothermal amplification (LAMP) in food testing for bacterial pathogens and fungal contaminants. Food Microbiol (2013) 0.87
Testicular nuclear receptor 4 (TR4) regulates UV light-induced responses via Cockayne syndrome B protein-mediated transcription-coupled DNA repair. J Biol Chem (2011) 0.87
Akt phosphorylates the TR3 orphan receptor and blocks its targeting to the mitochondria. Carcinogenesis (2008) 0.87
Interruption of KLF5 acetylation converts its function from tumor suppressor to tumor promoter in prostate cancer cells. Int J Cancer (2014) 0.87
Activation of JNK by TPA promotes apoptosis via PKC pathway in gastric cancer cells. World J Gastroenterol (2002) 0.87
Guanacastane-type diterpenoids from Coprinus radians. Phytochemistry (2012) 0.87
Suppression of androgen receptor enhances the self-renewal of mesenchymal stem cells through elevated expression of EGFR. Biochim Biophys Acta (2013) 0.86
Anti-hepatitis B virus active lactones from the traditional Chinese herb: Swertia mileensis. Chemistry (2011) 0.86
Mice lacking TR4 nuclear receptor develop mitochondrial myopathy with deficiency in complex I. Mol Endocrinol (2011) 0.86
Pre-clinical characterization of GMP grade CCL21-gene modified dendritic cells for application in a phase I trial in non-small cell lung cancer. J Transl Med (2008) 0.86
Glycosylation and production characteristics of epothilones in alkali-tolerant Sorangium cellulosum strain So0157-2. J Microbiol (2010) 0.85
Aldo-keto reductase-7A protects liver cells and tissues from acetaminophen-induced oxidative stress and hepatotoxicity. Hepatology (2011) 0.85
Increased PrLZ-mediated androgen receptor transactivation promotes prostate cancer growth at castration-resistant stage. Carcinogenesis (2012) 0.85
Heterodimer formation between c-Jun and Jun B proteins mediated by Epstein-Barr virus encoded latent membrane protein 1. Cell Signal (2004) 0.85
The biofilm-controlling functions of rechargeable antimicrobial N-halamine dental unit waterline tubing. J Clin Dent (2011) 0.85
Orphan receptor TR3 participates in cisplatin-induced apoptosis via Chk2 phosphorylation to repress intestinal tumorigenesis. Carcinogenesis (2011) 0.85
Effects of electroconvulsive stimulation on long-term potentiation and synaptophysin in the hippocampus of rats with depressive behavior. J ECT (2012) 0.84
Combination of taxanes, cisplatin and fluorouracil as induction chemotherapy for locally advanced head and neck cancer: a meta-analysis. PLoS One (2012) 0.84
The role of Akt on arsenic trioxide suppression of 3T3-L1 preadipocyte differentiation. Cell Res (2005) 0.84