Published in Mol Cell Biol on October 29, 2007
ATM/ATR checkpoint activation downregulates CDC25C to prevent mitotic entry with uncapped telomeres. EMBO J (2012) 1.69
Alpha4 is an essential regulator of PP2A phosphatase activity. Mol Cell (2009) 1.55
A B56gamma mutation in lung cancer disrupts the p53-dependent tumor-suppressor function of protein phosphatase 2A. Oncogene (2010) 1.09
p53 N-terminal phosphorylation: a defining layer of complex regulation. Carcinogenesis (2012) 1.06
Semaphorin 3A suppresses tumor growth and metastasis in mice melanoma model. PLoS One (2012) 1.05
The B56gamma3 regulatory subunit of protein phosphatase 2A (PP2A) regulates S phase-specific nuclear accumulation of PP2A and the G1 to S transition. J Biol Chem (2010) 1.05
Inhibition of Thr-55 phosphorylation restores p53 nuclear localization and sensitizes cancer cells to DNA damage. Proc Natl Acad Sci U S A (2008) 1.02
Gene expression in nontumoral liver tissue and recurrence-free survival in hepatitis C virus-positive hepatocellular carcinoma. Mol Cancer (2010) 1.01
Functions of B56-containing PP2As in major developmental and cancer signaling pathways. Life Sci (2010) 0.99
What goes on must come off: phosphatases gate-crash the DNA damage response. Trends Biochem Sci (2011) 0.97
PP2A:B56{epsilon}, a substrate of caspase-3, regulates p53-dependent and p53-independent apoptosis during development. J Biol Chem (2010) 0.96
Expression and distribution of PPP2R5C gene in leukemia. J Hematol Oncol (2011) 0.94
HIV-1-infected astrocytes and the microglial proteome. J Neuroimmune Pharmacol (2008) 0.92
Phosphorylation status of nuclear ribosomal protein S3 is reciprocally regulated by protein kinase C{delta} and protein phosphatase 2A. J Biol Chem (2009) 0.89
Differential gene expression profiles of PPP2R5C-siRNA-treated malignant T cells. DNA Cell Biol (2013) 0.89
Dissecting cellular responses to irradiation via targeted disruptions of the ATM-CHK1-PP2A circuit. Cell Cycle (2013) 0.88
Proliferation inhibition and apoptosis induction of imatinib-resistant chronic myeloid leukemia cells via PPP2R5C down-regulation. J Hematol Oncol (2013) 0.88
Conserved and distinct modes of CREB/ATF transcription factor regulation by PP2A/B56gamma and genotoxic stress. PLoS One (2010) 0.85
Ca2+/calmodulin-stimulated PDE1 regulates the beta-catenin/TCF signaling through PP2A B56 gamma subunit in proliferating vascular smooth muscle cells. FEBS J (2010) 0.85
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Regulation of nuclear-cytoplasmic shuttling and function of Family with sequence similarity 13, member A (Fam13a), by B56-containing PP2As and Akt. Mol Biol Cell (2015) 0.84
Prediction of functional phosphorylation sites by incorporating evolutionary information. Protein Cell (2012) 0.84
A novel triterpenoid isolated from the root bark of Ailanthus excelsa Roxb (Tree of Heaven), AECHL-1 as a potential anti-cancer agent. PLoS One (2009) 0.83
HIPK1 drives p53 activation to limit colorectal cancer cell growth. Cell Cycle (2013) 0.82
HEAT repeat 1 motif is required for B56γ-containing protein phosphatase 2A (B56γ-PP2A) holoenzyme assembly and tumor-suppressive function. J Biol Chem (2012) 0.81
Dynamic regulation of extracellular signal-regulated kinase (ERK) by protein phosphatase 2A regulatory subunit B56γ1 in nuclei induces cell migration. PLoS One (2013) 0.80
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LB100, a small molecule inhibitor of PP2A with potent chemo- and radio-sensitizing potential. Cancer Biol Ther (2015) 0.79
UBE4B targets phosphorylated p53 at serines 15 and 392 for degradation. Oncotarget (2016) 0.78
PPP2R5C Couples Hepatic Glucose and Lipid Homeostasis. PLoS Genet (2015) 0.78
Over Expression of Nucleophosmin and Nucleolin Contributes to the Suboptimal Activation of a G2/M Checkpoint in Ataxia Telangiectasia Fibroblasts. Mol Cell Pharmacol (2010) 0.77
Gene expression profiles of colonic mucosa in healthy young adult and senior dogs. PLoS One (2010) 0.77
B'-protein phosphatase 2A is a functional binding partner of delta-retroviral integrase. Nucleic Acids Res (2015) 0.76
Novel B55α-PP2A mutations in AML promote AKT T308 phosphorylation and sensitivity to AKT inhibitor-induced growth arrest. Oncotarget (2016) 0.75
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Identification of specific PP2A complexes involved in human cell transformation. Cancer Cell (2004) 3.29
Structure of the protein phosphatase 2A holoenzyme. Cell (2006) 3.07
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Phosphorylation of p53 serine 15 increases interaction with CBP. J Biol Chem (1998) 2.97
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Role for the PP2A/B56delta phosphatase in regulating 14-3-3 release from Cdc25 to control mitosis. Cell (2006) 2.15
p53: good cop/bad cop. Cell (2002) 2.11
Damage-mediated phosphorylation of human p53 threonine 18 through a cascade mediated by a casein 1-like kinase. Effect on Mdm2 binding. J Biol Chem (2000) 2.08
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Structure of protein phosphatase 2A core enzyme bound to tumor-inducing toxins. Cell (2006) 1.88
ATM signaling and genomic stability in response to DNA damage. Mutat Res (2005) 1.75
DNA-dependent acetylation of p53 by the transcription coactivator p300. J Biol Chem (2002) 1.59
A specific PP2A regulatory subunit, B56gamma, mediates DNA damage-induced dephosphorylation of p53 at Thr55. EMBO J (2007) 1.58
High complexity in the expression of the B' subunit of protein phosphatase 2A0. Evidence for the existence of at least seven novel isoforms. J Biol Chem (1996) 1.58
Role of serine/threonine protein phosphatase 2A in cancer. Cancer Lett (2001) 1.56
Novel phosphorylation sites of human tumour suppressor protein p53 at Ser20 and Thr18 that disrupt the binding of mdm2 (mouse double minute 2) protein are modified in human cancers. Biochem J (1999) 1.47
Phosphorylation on Thr-55 by TAF1 mediates degradation of p53: a role for TAF1 in cell G1 progression. Mol Cell (2004) 1.44
Phosphatases in apoptosis: to be or not to be, PP2A is in the heart of the question. Biochim Biophys Acta (2003) 1.39
Missense mutations but not allelic variants alter the function of ATM by dominant interference in patients with breast cancer. Proc Natl Acad Sci U S A (2002) 1.23
Genomic organization and mapping of the gene encoding the PP2A B56gamma regulatory subunit. Genomics (2002) 1.08
Phosphorylation of human p53 on Thr-55. Biochemistry (2000) 0.91
Expression of the B56delta subunit of protein phosphatase 2A and Mea1 in mouse spermatogenesis. Identification of a new B56gamma subunit (B56gamma4) specifically expressed in testis. Cytogenet Genome Res (2003) 0.91
PTEN tumor suppressor regulates p53 protein levels and activity through phosphatase-dependent and -independent mechanisms. Cancer Cell (2003) 5.13
Vorapaxar in the secondary prevention of atherothrombotic events. N Engl J Med (2012) 4.10
Genome-wide association analyses identify 18 new loci associated with serum urate concentrations. Nat Genet (2012) 3.04
Comparative transcriptional profiling of two contrasting rice genotypes under salinity stress during the vegetative growth stage. Plant Physiol (2005) 2.28
Simultaneous functional photoacoustic and ultrasonic endoscopy of internal organs in vivo. Nat Med (2012) 2.27
Endoscopic Functional Fourier Domain Common Path Optical Coherence Tomography for Microsurgery. IEEE J Sel Top Quantum Electron (2010) 1.88
Phosphorylation of human Sgo1 by NEK2A is essential for chromosome congression in mitosis. Cell Res (2007) 1.71
Niacin lipid efficacy is independent of both the niacin receptor GPR109A and free fatty acid suppression. Sci Transl Med (2012) 1.71
Mechanistic insights into maintenance of high p53 acetylation by PTEN. Mol Cell (2006) 1.68
MAVS recruits multiple ubiquitin E3 ligases to activate antiviral signaling cascades. Elife (2013) 1.63
Miniature fiber-optic force sensor based on low-coherence Fabry-Pérot interferometry for vitreoretinal microsurgery. Biomed Opt Express (2012) 1.63
Experimental results from a preclinical X-ray phase-contrast CT scanner. Proc Natl Acad Sci U S A (2012) 1.63
Glucocerebrosidase gene-deficient mouse recapitulates Gaucher disease displaying cellular and molecular dysregulation beyond the macrophage. Proc Natl Acad Sci U S A (2010) 1.60
A specific PP2A regulatory subunit, B56gamma, mediates DNA damage-induced dephosphorylation of p53 at Thr55. EMBO J (2007) 1.58
Incomplete specialty referral among children in community health centers. J Pediatr (2011) 1.54
Noninvasive photoacoustic and fluorescence sentinel lymph node identification using dye-loaded perfluorocarbon nanoparticles. ACS Nano (2010) 1.53
p53 acetylation is crucial for its transcription-independent proapoptotic functions. J Biol Chem (2009) 1.48
An acetylation switch in p53 mediates holo-TFIID recruitment. Mol Cell (2007) 1.48
Oxytocin is an anabolic bone hormone. Proc Natl Acad Sci U S A (2009) 1.44
Phosphorylation on Thr-55 by TAF1 mediates degradation of p53: a role for TAF1 in cell G1 progression. Mol Cell (2004) 1.44
Comparison study of gold nanohexapods, nanorods, and nanocages for photothermal cancer treatment. ACS Nano (2013) 1.36
Resveratrol inhibits invasion and metastasis of colorectal cancer cells via MALAT1 mediated Wnt/β-catenin signal pathway. PLoS One (2013) 1.34
ACE2 and Ang-(1-7) confer protection against development of diabetic retinopathy. Mol Ther (2011) 1.32
AAV-mediated cone rescue in a naturally occurring mouse model of CNGA3-achromatopsia. PLoS One (2012) 1.28
Short-term effect of cocoa product consumption on lipid profile: a meta-analysis of randomized controlled trials. Am J Clin Nutr (2010) 1.28
Human NUF2 interacts with centromere-associated protein E and is essential for a stable spindle microtubule-kinetochore attachment. J Biol Chem (2007) 1.27
ACTH protects against glucocorticoid-induced osteonecrosis of bone. Proc Natl Acad Sci U S A (2010) 1.26
Real-time 3D and 4D Fourier domain Doppler optical coherence tomography based on dual graphics processing units. Biomed Opt Express (2012) 1.25
Paraptosis accompanied by autophagy and apoptosis was induced by celastrol, a natural compound with influence on proteasome, ER stress and Hsp90. J Cell Physiol (2012) 1.25
Large-scale expression profiling and physiological characterization of jasmonic acid-mediated adaptation of barley to salinity stress. Plant Cell Environ (2007) 1.22
Glutathione peroxidase 1 is regulated by the c-Abl and Arg tyrosine kinases. J Biol Chem (2003) 1.22
A new theranostic system based on gold nanocages and phase-change materials with unique features for photoacoustic imaging and controlled release. J Am Chem Soc (2011) 1.18
Development of a prototype gantry system for preclinical x-ray phase-contrast computed tomography. Med Phys (2011) 1.16
Gold nanocages covered with thermally-responsive polymers for controlled release by high-intensity focused ultrasound. Nanoscale (2011) 1.15
Safety, biodistribution, and dosimetry of 99mTc-HYNIC-annexin V, a novel human recombinant annexin V for human application. J Nucl Med (2003) 1.14
Motion-compensated hand-held common-path Fourier-domain optical coherence tomography probe for image-guided intervention. Biomed Opt Express (2012) 1.14
Repression of hepatocyte nuclear factor 4alpha tumor suppressor p53: involvement of the ligand-binding domain and histone deacetylase activity. Mol Endocrinol (2002) 1.12
Gene therapy for retinitis pigmentosa caused by MFRP mutations: human phenotype and preliminary proof of concept. Hum Gene Ther (2012) 1.12
Tanshinone IIA sodium sulfonate protects against cardiotoxicity induced by doxorubicin in vitro and in vivo. Food Chem Toxicol (2009) 1.10
Phytochemical analysis of traditional Chinese medicine using liquid chromatography coupled with mass spectrometry. J Chromatogr A (2008) 1.10
Signal-to-noise ratio analysis of all-fiber common-path optical coherence tomography. Appl Opt (2008) 1.09
Tumour suppressor p53 down-regulates the expression of the human hepatocyte nuclear factor 4alpha (HNF4alpha) gene. Biochem J (2006) 1.09
Transcriptomic signatures in cartilage ageing. Arthritis Res Ther (2013) 1.07
In vivo photoacoustic mapping of lymphatic systems with plasmon-resonant nanostars. J Mater Chem (2011) 1.07
Optical coherence tomography scanning with a handheld vitreoretinal micromanipulator. Conf Proc IEEE Eng Med Biol Soc (2012) 1.07
Genome-wide detection of copy number variations using high-density SNP genotyping platforms in Holsteins. BMC Genomics (2013) 1.06
Investigation into the antioxidant activity and chemical composition of alcoholic extracts from defatted marigold (Tagetes erecta L.) residue. Fitoterapia (2011) 1.06
Interaction of SH2-Bbeta with RET is involved in signaling of GDNF-induced neurite outgrowth. J Cell Sci (2006) 1.06
Proteomics characterization of the cytotoxicity mechanism of ganoderic acid D and computer-automated estimation of the possible drug target network. Mol Cell Proteomics (2007) 1.05
N2'-->p3' phosphoramidate glycerol nucleic acid as a potential alternative genetic system. J Am Chem Soc (2009) 1.05
Parallel acoustic delay lines for photoacoustic tomography. J Biomed Opt (2012) 1.05
COX-2 contributes to P-glycoprotein-mediated multidrug resistance via phosphorylation of c-Jun at Ser63/73 in colorectal cancer. Carcinogenesis (2011) 1.05
Radioactive 198Au-doped nanostructures with different shapes for in vivo analyses of their biodistribution, tumor uptake, and intratumoral distribution. ACS Nano (2014) 1.04
A comparison of strategies for analyzing dichotomous outcomes in genome-wide association studies with general pedigrees. Genet Epidemiol (2011) 1.04
De novo assembly and characterization of Camelina sativa transcriptome by paired-end sequencing. BMC Genomics (2013) 1.04
Anti-tumor activity and apoptosis-regulation mechanisms of bufalin in various cancers: new hope for cancer patients. Asian Pac J Cancer Prev (2012) 1.04
AAV-mediated gene therapy in the guanylate cyclase (RetGC1/RetGC2) double knockout mouse model of Leber congenital amaurosis. Hum Gene Ther (2013) 1.03
Chronic label-free volumetric photoacoustic microscopy of melanoma cells in three-dimensional porous scaffolds. Biomaterials (2010) 1.03
Preservation of parotid function with uncomplicated conformal radiotherapy. Radiother Oncol (2002) 1.03
Inhibition of Thr-55 phosphorylation restores p53 nuclear localization and sensitizes cancer cells to DNA damage. Proc Natl Acad Sci U S A (2008) 1.02
Microtubule-binding natural products for cancer therapy. Planta Med (2010) 1.01
Molecular cloning and characterization of three novel lysozyme-like genes, predominantly expressed in the male reproductive system of humans, belonging to the c-type lysozyme/alpha-lactalbumin family. Biol Reprod (2005) 1.01
Preparation of curcumin-loaded liposomes and evaluation of their skin permeation and pharmacodynamics. Molecules (2012) 1.00
Noninvasive photoacoustic microscopy of living cells in two and three dimensions through enhancement by a metabolite dye. Angew Chem Int Ed Engl (2011) 1.00
TSP-1 secreted by bone marrow stromal cells contributes to retinal ganglion cell neurite outgrowth and survival. PLoS One (2008) 0.99
Multiple gene mutations, not the type of mutation, are the modifier of left ventricle hypertrophy in patients with hypertrophic cardiomyopathy. Mol Biol Rep (2013) 0.99
Photoacoustic tomography through a whole adult human skull with a photon recycler. J Biomed Opt (2012) 0.99
Increased expression of costimulatory markers CD134 and CD80 on interleukin-17 producing T cells in patients with systemic lupus erythematosus. Arthritis Res Ther (2010) 0.97
Cardio-protection of salvianolic acid B through inhibition of apoptosis network. PLoS One (2011) 0.97
An exotic species is the favorite prey of a native enemy. PLoS One (2011) 0.96
Labeling human mesenchymal stem cells with gold nanocages for in vitro and in vivo tracking by two-photon microscopy and photoacoustic microscopy. Theranostics (2013) 0.96
CD4+CD25+ T-cell populations expressing CD134 and GITR are associated with disease activity in patients with Wegener's granulomatosis. Nephrol Dial Transplant (2008) 0.96
Fiber supercapacitors utilizing pen ink for flexible/wearable energy storage. Adv Mater (2012) 0.95
Catalase is regulated by ubiquitination and proteosomal degradation. Role of the c-Abl and Arg tyrosine kinases. Biochemistry (2003) 0.95
Zuo Jin Wan, a Traditional Chinese Herbal Formula, Reverses P-gp-Mediated MDR In Vitro and In Vivo. Evid Based Complement Alternat Med (2013) 0.95
Involvement of multitargets in paeoniflorin-induced preconditioning. J Pharmacol Exp Ther (2006) 0.94
Ruggedness and robustness of conversion factors in method of simultaneous determination of multi-components with single reference standard. J Chromatogr A (2011) 0.94
From a single whole exome read to notions of clinical screening: primary ciliary dyskinesia and RSPH9 p.Lys268del in the Arabian Peninsula. Ann Hum Genet (2012) 0.94
Bufalin-loaded mPEG-PLGA-PLL-cRGD nanoparticles: preparation, cellular uptake, tissue distribution, and anticancer activity. Int J Nanomedicine (2012) 0.94
Spatial Latent Class Analysis Model for Spatially Distributed Multivariate Binary Data. Comput Stat Data Anal (2009) 0.94
Human papillomavirus type 16 E6 and E7 oncoproteins upregulate c-IAP2 gene expression and confer resistance to apoptosis. Oncogene (2005) 0.93
Interaction of Skp1 with CENP-E at the midbody is essential for cytokinesis. Biochem Biophys Res Commun (2006) 0.93
Matrix metalloproteinase-9 induces cardiac fibroblast migration, collagen and cytokine secretion: inhibition by salvianolic acid B from Salvia miltiorrhiza. Phytomedicine (2011) 0.92
Mutations in NEXN, a Z-disc gene, are associated with hypertrophic cardiomyopathy. Am J Hum Genet (2010) 0.92
Photoacoustic sentinel lymph node imaging with self-assembled copper neodecanoate nanoparticles. ACS Nano (2012) 0.92
Antigen-specific T cell functions are suppressed over the estrogen-dendritic cell-indoleamine 2,3-dioxygenase axis. Steroids (2004) 0.92
Identification of DNA-binding proteins by combining auto-cross covariance transformation and ensemble learning. IEEE Trans Nanobioscience (2016) 0.92
Population size and time since island isolation determine genetic diversity loss in insular frog populations. Mol Ecol (2014) 0.91
The role of p53 deacetylation in p21Waf1 regulation by laminar flow. J Biol Chem (2003) 0.90
Selective tropism of the recombinant adeno-associated virus 9 serotype for rat cardiac tissue. J Gene Med (2010) 0.90
Cardioprotection and matrix metalloproteinase-9 regulation of salvianolic acids on myocardial infarction in rats. Planta Med (2009) 0.90
Therapeutic potential of IFN-gamma-modified dendritic cells in acute and chronic experimental allergic encephalomyelitis. Int Immunol (2004) 0.90
Common-Path Optical Coherence Tomography for Biomedical Imaging and Sensing. J Opt Soc Korea (2010) 0.90
Association of estimated glomerular filtration rate and urinary uromodulin concentrations with rare variants identified by UMOD gene region sequencing. PLoS One (2012) 0.89
Improved heterologous gene expression in Trichoderma reesei by cellobiohydrolase I gene (cbh1) promoter optimization. Acta Biochim Biophys Sin (Shanghai) (2008) 0.89
Reduced prefrontal activation during Tower of London in first-episode schizophrenia: a multi-channel near-infrared spectroscopy study. Neurosci Lett (2010) 0.89
Cytotoxic triterpenoids from Ganoderma lucidum. Phytochemistry (2010) 0.89