PubRank

Steven M Block

Author PubWeight™ 109.15‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Optical trapping. Rev Sci Instrum 2004 7.15
2 Direct observation of base-pair stepping by RNA polymerase. Nature 2005 6.29
3 Ubiquitous transcriptional pausing is independent of RNA polymerase backtracking. Cell 2003 3.92
4 Kinesin moves by an asymmetric hand-over-hand mechanism. Science 2003 3.83
5 An automated two-dimensional optical force clamp for single molecule studies. Biophys J 2002 3.57
6 Nanomechanical measurements of the sequence-dependent folding landscapes of single nucleic acid hairpins. Proc Natl Acad Sci U S A 2006 3.56
7 Sequence-resolved detection of pausing by single RNA polymerase molecules. Cell 2006 3.50
8 Backtracking by single RNA polymerase molecules observed at near-base-pair resolution. Nature 2003 3.50
9 Direct measurement of the full, sequence-dependent folding landscape of a nucleic acid. Science 2006 3.49
10 Direct observation of hierarchical folding in single riboswitch aptamers. Science 2008 3.22
11 Passive all-optical force clamp for high-resolution laser trapping. Phys Rev Lett 2005 3.13
12 Coordination of opposite-polarity microtubule motors. J Cell Biol 2002 3.04
13 Individual dimers of the mitotic kinesin motor Eg5 step processively and support substantial loads in vitro. Nat Cell Biol 2006 2.73
14 Stepping and stretching. How kinesin uses internal strain to walk processively. J Biol Chem 2003 2.60
15 High-resolution, single-molecule measurements of biomolecular motion. Annu Rev Biophys Biomol Struct 2007 2.58
16 Applied force reveals mechanistic and energetic details of transcription termination. Cell 2008 2.45
17 Simultaneous, coincident optical trapping and single-molecule fluorescence. Nat Methods 2004 2.20
18 Sequence-dependent pausing of single lambda exonuclease molecules. Science 2003 1.88
19 Backsteps induced by nucleotide analogs suggest the front head of kinesin is gated by strain. Proc Natl Acad Sci U S A 2006 1.85
20 Forward and reverse motion of single RecBCD molecules on DNA. Biophys J 2004 1.82
21 Single-molecule studies of RNA polymerase: motoring along. Annu Rev Biochem 2008 1.80
22 Single-molecule, motion-based DNA sequencing using RNA polymerase. Science 2006 1.69
23 Binding and translocation of termination factor rho studied at the single-molecule level. J Mol Biol 2012 1.58
24 Combined optical trapping and single-molecule fluorescence. J Biol 2003 1.52
25 Trigger loop dynamics mediate the balance between the transcriptional fidelity and speed of RNA polymerase II. Proc Natl Acad Sci U S A 2012 1.51
26 A universal pathway for kinesin stepping. Nat Struct Mol Biol 2011 1.43
27 E. coli NusG inhibits backtracking and accelerates pause-free transcription by promoting forward translocation of RNA polymerase. J Mol Biol 2010 1.36
28 Picocalorimetry of transcription by RNA polymerase. Biophys J 2005 1.33
29 Direct observation of the binding state of the kinesin head to the microtubule. Nature 2009 1.32
30 Folding and unfolding single RNA molecules under tension. Curr Opin Chem Biol 2008 1.26
31 Pulling on the nascent RNA during transcription does not alter kinetics of elongation or ubiquitous pausing. Mol Cell 2006 1.26
32 Statistical kinetics of macromolecular dynamics. Biophys J 2005 1.24
33 Optical tweezers study life under tension. Nat Photonics 2011 1.22
34 Single-molecule studies of RNA polymerase: one singular sensation, every little step it takes. Mol Cell 2011 1.21
35 Measurement of the effective focal shift in an optical trap. Opt Lett 2005 1.19
36 Eg5 steps it up! Cell Div 2006 1.18
37 Resource Letter: LBOT-1: Laser-based optical tweezers. Am J Phys 2003 1.17
38 Direct observation of cotranscriptional folding in an adenine riboswitch. Science 2012 1.13
39 Reconstructing folding energy landscapes by single-molecule force spectroscopy. Annu Rev Biophys 2014 1.12
40 Folding energy landscape of the thiamine pyrophosphate riboswitch aptamer. Proc Natl Acad Sci U S A 2012 1.07
41 The importance of lattice defects in katanin-mediated microtubule severing in vitro. Biophys J 2002 1.07
42 Precision steering of an optical trap by electro-optic deflection. Opt Lett 2008 1.00
43 Applied force provides insight into transcriptional pausing and its modulation by transcription factor NusA. Mol Cell 2011 0.97
44 Force and premature binding of ADP can regulate the processivity of individual Eg5 dimers. Biophys J 2009 0.92
45 Direct measurements of kinesin torsional properties reveal flexible domains and occasional stalk reversals during stepping. Proc Natl Acad Sci U S A 2009 0.91
46 Kinesin steps do not alternate in size. Biophys J 2007 0.90
47 Transcription factors TFIIF and TFIIS promote transcript elongation by RNA polymerase II by synergistic and independent mechanisms. Proc Natl Acad Sci U S A 2014 0.88
48 On the origin of kinesin limping. Biophys J 2009 0.88
49 A not-so-cheap stunt. Science 2002 0.88
50 Morphometric assessment of collagen accumulation in germinal matrix vessels of premature human neonates. Neuropathol Appl Neurobiol 2005 0.87
51 Efficient reconstitution of transcription elongation complexes for single-molecule studies of eukaryotic RNA polymerase II. Transcription 2012 0.85
52 Electrostatics of nucleic acid folding under conformational constraint. J Am Chem Soc 2012 0.85
53 Anatomical analysis of the developing cerebral vasculature in premature neonates: absence of precapillary arteriole-to-venous shunts. Pediatr Res 2002 0.82
54 Subependymal veins in premature neonates: implications for hemorrhage. Pediatr Neurol 2004 0.81
55 Single-molecule studies of RNAPII elongation. Biochim Biophys Acta 2012 0.80
56 An optical apparatus for rotation and trapping. Methods Enzymol 2010 0.79
57 Temporal expression pattern of cerebrovascular endothelial cell alkaline phosphatase during human gestation. J Neuropathol Exp Neurol 2002 0.78
58 Not so lame after all: kinesin still walks with a hobbled head. J Gen Physiol 2007 0.78
59 Attitudes and expectations about music therapy for premature infants among staff in a neonatal intensive care unit. Altern Ther Health Med 2004 0.78
60 UK defence group's structure could limit its usefulness. Nature 2009 0.75
61 Germinal matrix cells associate with veins and a glial scaffold in the human fetal brain. Brain Res Dev Brain Res 2005 0.75