Published in J Appl Physiol (1985) on November 08, 2007
Identification of asthma phenotypes using cluster analysis in the Severe Asthma Research Program. Am J Respir Crit Care Med (2009) 7.17
A multivariate analysis of risk factors for the air-trapping asthmatic phenotype as measured by quantitative CT analysis. Chest (2008) 2.38
Asthma is inversely associated with Helicobacter pylori status in an urban population. PLoS One (2008) 2.04
Severe asthma: lessons learned from the National Heart, Lung, and Blood Institute Severe Asthma Research Program. Am J Respir Crit Care Med (2011) 1.76
Sex dependence of airflow limitation and air trapping in children with severe asthma. J Allergy Clin Immunol (2011) 1.64
Bronchial thermoplasty: Long-term safety and effectiveness in patients with severe persistent asthma. J Allergy Clin Immunol (2013) 1.45
Registration-based assessment of regional lung function via volumetric CT images of normal subjects vs. severe asthmatics. J Appl Physiol (1985) (2013) 1.22
An african-specific functional polymorphism in KCNMB1 shows sex-specific association with asthma severity. Hum Mol Genet (2008) 1.15
Narrative review: the role of Th2 immune pathway modulation in the treatment of severe asthma and its phenotypes. Ann Intern Med (2010) 1.13
Restoration of corticosteroid sensitivity by p38 mitogen activated protein kinase inhibition in peripheral blood mononuclear cells from severe asthma. PLoS One (2012) 1.07
Asthma outcomes: pulmonary physiology. J Allergy Clin Immunol (2012) 1.02
Bronchodilation response to deep inspirations in asthma is dependent on airway distensibility and air trapping. J Appl Physiol (1985) (2010) 1.00
Three-dimensional imaging of ventilation dynamics in asthmatics using multiecho projection acquisition with constrained reconstruction. Magn Reson Med (2009) 0.95
Lung development and the host response to influenza A virus are altered by different doses of neonatal oxygen in mice. Am J Physiol Lung Cell Mol Physiol (2012) 0.95
Techniques of assessing small airways dysfunction. Eur Clin Respir J (2014) 0.94
Platelet activation, P-selectin, and eosinophil β1-integrin activation in asthma. Am J Respir Crit Care Med (2012) 0.94
Expiratory CT scan in patients with normal inspiratory CT scan: a finding of obliterative bronchiolitis and other causes of bronchiolar obstruction. Multidiscip Respir Med (2013) 0.94
Distinguishing characteristics of difficult-to-control asthma in inner-city children and adolescents. J Allergy Clin Immunol (2016) 0.93
Small airways dysfunction in asthma: evaluation and management to improve asthma control. Allergy Asthma Immunol Res (2014) 0.92
Secretory leukocyte protease inhibitor plays an important role in the regulation of allergic asthma in mice. J Immunol (2011) 0.92
Apolipoprotein mimetic peptides: a new approach for the treatment of asthma. Front Pharmacol (2012) 0.89
Mesenchymal stromal cells mediate Aspergillus hyphal extract-induced allergic airway inflammation by inhibition of the Th17 signaling pathway. Stem Cells Transl Med (2014) 0.89
Quantitative assessment of multiscale structural and functional alterations in asthmatic populations. J Appl Physiol (1985) (2015) 0.89
Impact of extrafine formulations of inhaled corticosteroids/long-acting beta-2 agonist combinations on patient-related outcomes in asthma and COPD. Patient Relat Outcome Meas (2014) 0.87
How variability in clinical phenotypes should guide research into disease mechanisms in asthma. Ann Am Thorac Soc (2013) 0.86
Improved CT-based estimate of pulmonary gas trapping accounting for scanner and lung-volume variations in a multicenter asthmatic study. J Appl Physiol (1985) (2014) 0.86
The irreversible component of persistent asthma. J Allergy Clin Immunol (2009) 0.86
Clinical heterogeneity in the severe asthma research program. Ann Am Thorac Soc (2013) 0.84
An RGS4-mediated phenotypic switch of bronchial smooth muscle cells promotes fixed airway obstruction in asthma. PLoS One (2012) 0.84
Severe asthma in childhood: recent advances in phenotyping and pathogenesis. Curr Opin Allergy Clin Immunol (2012) 0.84
Lung penetration and patient adherence considerations in the management of asthma: role of extra-fine formulations. J Asthma Allergy (2013) 0.84
Gene-based association identifies SPATA13-AS1 as a pharmacogenomic predictor of inhaled short-acting beta-agonist response in multiple population groups. Pharmacogenomics J (2014) 0.83
Small airway dysfunction is associated to excessive bronchoconstriction in asthmatic patients. Respir Res (2014) 0.82
Airway closure on imaging relates to airway hyperresponsiveness and peripheral airway disease in asthma. J Appl Physiol (1985) (2012) 0.82
Markers of vascular perturbation correlate with airway structural change in asthma. Am J Respir Crit Care Med (2013) 0.81
Hyperpolarized Helium-3 MRI of exercise-induced bronchoconstriction during challenge and therapy. J Magn Reson Imaging (2013) 0.81
Biomarkers in asthma: a real hope to better manage asthma. Clin Chest Med (2012) 0.80
Asthma control: the right inhaler for the right patient. Adv Ther (2015) 0.80
Viral bronchiolitis in young rats causes small airway lesions that correlate with reduced lung function. Am J Respir Cell Mol Biol (2013) 0.80
Clinical Implications of Having Reduced Mid Forced Expiratory Flow Rates (FEF25-75), Independently of FEV1, in Adult Patients with Asthma. PLoS One (2015) 0.79
Using Periostin as a Biomarker in the Treatment of Asthma. Allergy Asthma Immunol Res (2016) 0.79
Extrafine inhaled corticosteroid therapy in the control of asthma. J Asthma Allergy (2013) 0.78
Functional imaging of the lungs with gas agents. J Magn Reson Imaging (2015) 0.78
Randomised, double-blind, placebo-controlled crossover study to investigate different dosing regimens of olodaterol delivered via Respimat® in patients with moderate to severe persistent asthma. Respir Res (2015) 0.78
Concave pattern of a maximal expiratory flow-volume curve: a sign of airflow limitation in adult bronchial asthma. Pulm Med (2012) 0.78
Severe Asthma in Children: Lessons Learned and Future Directions. J Allergy Clin Immunol Pract (2016) 0.77
CD11b+ and Sca-1+ Cells Exert the Main Beneficial Effects of Systemically Administered Bone Marrow-Derived Mononuclear Cells in a Murine Model of Mixed Th2/Th17 Allergic Airway Inflammation. Stem Cells Transl Med (2016) 0.77
TNFα-blockade stabilizes local airway hyperresponsiveness during TLR-induced exacerbations in murine model of asthma. Respir Res (2015) 0.77
Redistribution of inhaled hyperpolarized 3He gas during breath-hold differs by asthma severity. J Appl Physiol (1985) (2015) 0.76
Bidirectional Counterregulation of Human Lung Mast Cell and Airway Smooth Muscle β2 Adrenoceptors. J Immunol (2015) 0.76
Diagnostic and prognostic utility of mid-expiratory flow rate in older community-dwelling persons with respiratory symptoms, but without chronic obstructive pulmonary disease. BMC Pulm Med (2015) 0.75
Dividing the FEV1 into its component parts. J Appl Physiol (1985) (2008) 0.75
Vital capacity and inspiratory capacity as additional parameters to evaluate bronchodilator response in asthmatic patients: a cross sectional study. BMC Pulm Med (2012) 0.75
Clinical Roles of Lung Volumes Detected by Body Plethysmography and Helium Dilution in Asthmatic Patients: A Correlation and Diagnosis Analysis. Sci Rep (2017) 0.75
Quantitative Assessment of Global and Regional Air Trappings Using Non-Rigid Registration and Regional Specific Volume Change of Inspiratory/Expiratory CT Scans: Studies on Healthy Volunteers and Asthmatics. Korean J Radiol (2015) 0.75
Study of correlation between forced vital capacity and demand for healthcare services in severe asthmatics. Multidiscip Respir Med (2015) 0.75
Psychological aspects in asthma: do psychological factors affect asthma management? Asthma Res Pract (2015) 0.75
Airway factor XIII associates with type 2 inflammation and airway obstruction in asthmatic patients. J Allergy Clin Immunol (2015) 0.75
Fixed airways obstruction among patients with severe asthma: findings from the Singapore General Hospital-Severe Asthma Phenotype Study. BMC Pulm Med (2014) 0.75
Relationship between the baseline alveolar volume-to-total lung capacity ratio and airway responsiveness. Respirology (2014) 0.75
Small airways disease and severe asthma. World Allergy Organ J (2017) 0.75
Cumulative association of five genetic variants with prostate cancer. N Engl J Med (2008) 15.34
An official American Thoracic Society/European Respiratory Society statement: asthma control and exacerbations: standardizing endpoints for clinical asthma trials and clinical practice. Am J Respir Crit Care Med (2009) 9.38
The Salmeterol Multicenter Asthma Research Trial: a comparison of usual pharmacotherapy for asthma or usual pharmacotherapy plus salmeterol. Chest (2006) 8.43
International ERS/ATS guidelines on definition, evaluation and treatment of severe asthma. Eur Respir J (2013) 8.39
Can guideline-defined asthma control be achieved? The Gaining Optimal Asthma ControL study. Am J Respir Crit Care Med (2004) 8.39
Genetic epidemiology of COPD (COPDGene) study design. COPD (2010) 7.67
Daily versus as-needed corticosteroids for mild persistent asthma. N Engl J Med (2005) 7.61
Identification of asthma phenotypes using cluster analysis in the Severe Asthma Research Program. Am J Respir Crit Care Med (2009) 7.17
Characterization of the severe asthma phenotype by the National Heart, Lung, and Blood Institute's Severe Asthma Research Program. J Allergy Clin Immunol (2007) 6.33
Tiotropium bromide step-up therapy for adults with uncontrolled asthma. N Engl J Med (2010) 6.19
Efficacy of esomeprazole for treatment of poorly controlled asthma. N Engl J Med (2009) 5.90
Mepolizumab for severe eosinophilic asthma (DREAM): a multicentre, double-blind, placebo-controlled trial. Lancet (2012) 5.82
Pulmonary arterial enlargement and acute exacerbations of COPD. N Engl J Med (2012) 5.54
An official ATS clinical practice guideline: interpretation of exhaled nitric oxide levels (FENO) for clinical applications. Am J Respir Crit Care Med (2011) 5.53
Early intervention with budesonide in mild persistent asthma: a randomised, double-blind trial. Lancet (2003) 5.10
Use of regularly scheduled albuterol treatment in asthma: genotype-stratified, randomised, placebo-controlled cross-over trial. Lancet (2004) 5.01
Oral glucocorticoid-sparing effect of mepolizumab in eosinophilic asthma. N Engl J Med (2014) 4.95
Two genome-wide association studies of aggressive prostate cancer implicate putative prostate tumor suppressor gene DAB2IP. J Natl Cancer Inst (2007) 4.85
Effectiveness and safety of bronchial thermoplasty in the treatment of severe asthma: a multicenter, randomized, double-blind, sham-controlled clinical trial. Am J Respir Crit Care Med (2009) 4.83
Persistent activation of an innate immune response translates respiratory viral infection into chronic lung disease. Nat Med (2008) 4.70
Active albuterol or placebo, sham acupuncture, or no intervention in asthma. N Engl J Med (2011) 4.68
Respiratory effects of exposure to diesel traffic in persons with asthma. N Engl J Med (2007) 4.58
Randomized comparison of strategies for reducing treatment in mild persistent asthma. N Engl J Med (2007) 4.40
Airway microbiota and bronchial hyperresponsiveness in patients with suboptimally controlled asthma. J Allergy Clin Immunol (2010) 4.38
Management of asthma based on exhaled nitric oxide in addition to guideline-based treatment for inner-city adolescents and young adults: a randomised controlled trial. Lancet (2008) 4.06
GOLD 2011 disease severity classification in COPDGene: a prospective cohort study. Lancet Respir Med (2012) 3.98
Genomewide association between GLCCI1 and response to glucocorticoid therapy in asthma. N Engl J Med (2011) 3.80
Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations. Nat Genet (2011) 3.68
Estrogen-receptor polymorphisms and effects of estrogen replacement on high-density lipoprotein cholesterol in women with coronary disease. N Engl J Med (2002) 3.68
Significant variability in response to inhaled corticosteroids for persistent asthma. J Allergy Clin Immunol (2002) 3.66
Lansoprazole for children with poorly controlled asthma: a randomized controlled trial. JAMA (2012) 3.40
Asthma endotypes: a new approach to classification of disease entities within the asthma syndrome. J Allergy Clin Immunol (2011) 3.35
Hyperproliferative apoptosis-resistant endothelial cells in idiopathic pulmonary arterial hypertension. Am J Physiol Lung Cell Mol Physiol (2007) 3.28
Uniform definition of asthma severity, control, and exacerbations: document presented for the World Health Organization Consultation on Severe Asthma. J Allergy Clin Immunol (2010) 3.12
A randomized, controlled, phase 2 study of AMG 317, an IL-4Ralpha antagonist, in patients with asthma. Am J Respir Crit Care Med (2010) 3.11
Detection of lung cancer by sensor array analyses of exhaled breath. Am J Respir Crit Care Med (2005) 2.94
Effects of treatment with anti-immunoglobulin E antibody omalizumab on airway inflammation in allergic asthma. Am J Respir Crit Care Med (2004) 2.81
Smoking affects response to inhaled corticosteroids or leukotriene receptor antagonists in asthma. Am J Respir Crit Care Med (2007) 2.81
Distinguishing severe asthma phenotypes: role of age at onset and eosinophilic inflammation. J Allergy Clin Immunol (2004) 2.80
Efficacy of a new once-daily long-acting inhaled beta2-agonist indacaterol versus twice-daily formoterol in COPD. Thorax (2010) 2.79
Germline mutations and sequence variants of the macrophage scavenger receptor 1 gene are associated with prostate cancer risk. Nat Genet (2002) 2.76
Prevalence of viral respiratory tract infections in children with asthma. J Allergy Clin Immunol (2006) 2.67
Gene-gene interaction in asthma: IL4RA and IL13 in a Dutch population with asthma. Am J Hum Genet (2001) 2.61
An endothelial apelin-FGF link mediated by miR-424 and miR-503 is disrupted in pulmonary arterial hypertension. Nat Med (2012) 2.59
Natural killer T cells in the lungs of patients with asthma. J Allergy Clin Immunol (2009) 2.57