Published in Differentiation on November 01, 2007
Regulation of Hippo signaling by EGFR-MAPK signaling through Ajuba family proteins. Dev Cell (2013) 1.78
Epidermal growth factor receptor signaling synergizes with Hedgehog/GLI in oncogenic transformation via activation of the MEK/ERK/JUN pathway. Cancer Res (2009) 1.78
Epithelial inflammation resulting from an inherited loss-of-function mutation in EGFR. J Invest Dermatol (2014) 1.58
EGFR-mutated lung cancer: a paradigm of molecular oncology. Oncotarget (2010) 1.53
Growth factors and corneal epithelial wound healing. Brain Res Bull (2009) 1.47
The EGFR family: not so prototypical receptor tyrosine kinases. Cold Spring Harb Perspect Biol (2014) 1.39
A two-tiered mechanism of EGFR inhibition by RALT/MIG6 via kinase suppression and receptor degradation. J Cell Biol (2010) 1.35
High glucose suppresses epidermal growth factor receptor/phosphatidylinositol 3-kinase/Akt signaling pathway and attenuates corneal epithelial wound healing. Diabetes (2009) 1.26
Epidermal growth factor receptor inhibition in lung cancer: the evolving role of individualized therapy. Cancer Metastasis Rev (2010) 1.26
RNA interference against hepatic epidermal growth factor receptor has suppressive effects on liver regeneration in rats. Am J Pathol (2010) 1.05
The role of irreversible HER family inhibition in the treatment of patients with non-small cell lung cancer. Oncologist (2011) 1.04
LRIG1 negatively regulates the oncogenic EGF receptor mutant EGFRvIII. Oncogene (2008) 1.04
Cholesteatoma fibroblasts promote epithelial cell proliferation through overexpression of epiregulin. PLoS One (2013) 0.99
Blocking epidermal growth factor receptor activation by 3,3'-diindolylmethane suppresses ovarian tumor growth in vitro and in vivo. J Pharmacol Exp Ther (2011) 0.99
Illuminating epidermal growth factor receptor densities on filopodia through plasmon coupling. ACS Nano (2011) 0.99
Intercellular propagation of extracellular signal-regulated kinase activation revealed by in vivo imaging of mouse skin. Elife (2015) 0.97
Oncogenic cooperation between SOCS family proteins and EGFR identified using a Drosophila epithelial transformation model. Genes Dev (2012) 0.97
Targeting the EGF receptor for ovarian cancer therapy. J Oncol (2009) 0.96
Lysine 63-linked polyubiquitination is required for EGF receptor degradation. Proc Natl Acad Sci U S A (2013) 0.96
E3 ubiquitin ligases in ErbB receptor quantity control. Semin Cell Dev Biol (2010) 0.96
Flagellin-induced corneal antimicrobial peptide production and wound repair involve a novel NF-kappaB-independent and EGFR-dependent pathway. PLoS One (2010) 0.96
Periostin cooperates with mutant p53 to mediate invasion through the induction of STAT1 signaling in the esophageal tumor microenvironment. Oncogenesis (2013) 0.96
Cooperative Hedgehog-EGFR signaling. Front Biosci (Landmark Ed) (2012) 0.95
Role for cumulus cell-produced EGF-like ligands during primate oocyte maturation in vitro. Am J Physiol Endocrinol Metab (2009) 0.95
Stretch-induced fetal type II cell differentiation is mediated via ErbB1-ErbB4 interactions. J Biol Chem (2012) 0.92
The metastasis-promoting S100A4 protein confers neuroprotection in brain injury. Nat Commun (2012) 0.92
Characterization of membranous and cytoplasmic EGFR expression in human normal renal cortex and renal cell carcinoma. J Biomed Sci (2009) 0.92
The role of EGF-EGFR signalling pathway in hepatocellular carcinoma inflammatory microenvironment. J Cell Mol Med (2013) 0.92
Live-cell fluorescence imaging reveals high stoichiometry of Grb2 binding to the EGF receptor sustained during endocytosis. J Cell Sci (2013) 0.91
Role of receptor tyrosine kinases and their ligands in glioblastoma. Cells (2014) 0.91
EGFR signaling pathway and related-miRNAs in age-related diseases: the example of miR-221 and miR-222. Front Genet (2012) 0.91
Lineage-specific co-evolution of the Egf receptor/ligand signaling system. BMC Evol Biol (2010) 0.90
EGFR Signaling in Liver Diseases. Int J Mol Sci (2015) 0.90
Resveratrol induces long-lasting IL-8 expression and peculiar EGFR activation/distribution in human keratinocytes: mechanisms and implications for skin administration. PLoS One (2013) 0.89
Delayed cutaneous wound healing and aberrant expression of hair follicle stem cell markers in mice selectively lacking Ctip2 in epidermis. PLoS One (2012) 0.88
Epidermal Growth Factor Receptor (EGFR) Crosstalks in Liver Cancer. Cancers (Basel) (2011) 0.86
The EGFR-HER2 module: a stem cell approach to understanding a prime target and driver of solid tumors. Oncogene (2015) 0.85
Pulmonary enteric adenocarcinoma: a study of the clinicopathologic and molecular status of nine cases. Int J Clin Exp Pathol (2014) 0.85
PPARβ/δ and PPARγ maintain undifferentiated phenotypes of mouse adult neural precursor cells from the subventricular zone. Front Cell Neurosci (2015) 0.85
Activated epidermal growth factor receptor in ovarian cancer. Cancer Treat Res (2009) 0.84
BBS4 and BBS5 show functional redundancy in the BBSome to regulate the degradative sorting of ciliary sensory receptors. Sci Rep (2015) 0.84
Epidermal growth factor receptor (EGFR) signaling regulates epiphyseal cartilage development through β-catenin-dependent and -independent pathways. J Biol Chem (2013) 0.84
Regulation of receptor tyrosine kinase ligand processing. Cold Spring Harb Perspect Biol (2014) 0.83
Targeted therapies in the treatment of advanced hepatocellular carcinoma. Clin Med Insights Oncol (2013) 0.83
Biomarkers and endosalpingiosis in the ovarian and tubal microenvironment of women at high-risk for pelvic serous carcinoma. Am J Cancer Res (2014) 0.83
Sur8/Shoc2 promotes cell motility and metastasis through activation of Ras-PI3K signaling. Oncotarget (2015) 0.83
Sperm epidermal growth factor receptor (EGFR) mediates α7 acetylcholine receptor (AChR) activation to promote fertilization. J Biol Chem (2012) 0.83
Prolidase directly binds and activates epidermal growth factor receptor and stimulates downstream signaling. J Biol Chem (2012) 0.82
Kappa opioid receptor contributes to EGF-stimulated neurite extension in development. Proc Natl Acad Sci U S A (2010) 0.82
Proteomic analysis of temporally stimulated ovarian cancer cells for biomarker discovery. Mol Cell Proteomics (2012) 0.81
Protein tyrosine phosphatase PTPN3 inhibits lung cancer cell proliferation and migration by promoting EGFR endocytic degradation. Oncogene (2014) 0.81
A new drug delivery method of bispecific ligand-directed toxins, which reduces toxicity and promotes efficacy in a model of orthotopic pancreatic cancer. Pancreas (2010) 0.81
Profile of erlotinib and its potential in the treatment of advanced ovarian carcinoma. Onco Targets Ther (2013) 0.81
Oligomerization of the Nrdp1 E3 ubiquitin ligase is necessary for efficient autoubiquitination but not ErbB3 ubiquitination. J Biol Chem (2014) 0.81
Strain-induced differentiation of fetal type II epithelial cells is mediated via the integrin α6β1-ADAM17/tumor necrosis factor-α-converting enzyme (TACE) signaling pathway. J Biol Chem (2013) 0.80
ErbB receptor-driven prolactinomas respond to targeted lapatinib treatment in female transgenic mice. Endocrinology (2015) 0.80
Epithelioid Sarcoma: Opportunities for Biology-Driven Targeted Therapy. Front Oncol (2015) 0.80
Decoding epithelial signals: critical role for the epidermal growth factor receptor in controlling intestinal transport function. Acta Physiol (Oxf) (2008) 0.80
EGF-dependent re-routing of vesicular recycling switches spontaneous phosphorylation suppression to EGFR signaling. Elife (2015) 0.80
ERBB3 is required for metastasis formation of melanoma cells. Oncogenesis (2014) 0.79
Mechanisms underlying skin disorders induced by EGFR inhibitors. Mol Cell Oncol (2015) 0.78
Diagnostic values of vascular endothelial growth factor and epidermal growth factor receptor for benign and malignant hydrothorax. Chin Med J (Engl) (2015) 0.78
Hemangiosarcoma and its cancer stem cell subpopulation are effectively killed by a toxin targeted through epidermal growth factor and urokinase receptors. Int J Cancer (2013) 0.78
IL-1beta signals through the EGF receptor and activates Egr-1 through MMP-ADAM. PLoS One (2012) 0.78
The Role of EGFR/ERK/ELK-1 MAP Kinase Pathway in the Underlying Damage to Diabetic Rat Skin. Indian J Dermatol (2013) 0.78
Ligand-based targeted therapy: a novel strategy for hepatocellular carcinoma. Int J Nanomedicine (2016) 0.77
Molecular alterations of EGFR in small intestinal adenocarcinoma. Int J Colorectal Dis (2013) 0.77
Combined EGFR and VEGFR versus single EGFR signaling pathways inhibition therapy for NSCLC: a systematic review and meta-analysis. PLoS One (2012) 0.77
Early signaling dynamics of the epidermal growth factor receptor. Proc Natl Acad Sci U S A (2016) 0.77
Endocytosis of Ubiquitylation-Deficient EGFR Mutants via Clathrin-Coated Pits is Mediated by Ubiquitylation. Traffic (2015) 0.77
Cytoplasmic retention of a nucleocytoplasmic protein TBC1D3 by microtubule network is required for enhanced EGFR signaling. PLoS One (2014) 0.76
MET Gene Amplification and MET Receptor Activation Are Not Sufficient to Predict Efficacy of Combined MET and EGFR Inhibitors in EGFR TKI-Resistant NSCLC Cells. PLoS One (2015) 0.76
miRNAs and resistance to EGFR-TKIs in EGFR-mutant non-small cell lung cancer: beyond 'traditional mechanisms' of resistance. Ecancermedicalscience (2015) 0.76
Adrenal cortical neoplasms: a study of clinicopathological features related to epidermal growth factor receptor gene status. Diagn Pathol (2014) 0.76
Evolution of the EGFR pathway in Metazoa and its diversification in the planarian Schmidtea mediterranea. Sci Rep (2016) 0.76
Mineralocorticoid receptor interaction with SP1 generates a new response element for pathophysiologically relevant gene expression. Nucleic Acids Res (2013) 0.76
Amplification of Cellular Oncogenes in Solid Tumors. N Am J Med Sci (2015) 0.76
ErbB3 mRNA leukocyte levels as a biomarker for major depressive disorder. BMC Psychiatry (2012) 0.75
Methods to study endocytic trafficking of the EGF receptor. Methods Cell Biol (2015) 0.75
Preclinical studies of a Pro-antibody-drug conjugate designed to selectively target EGFR-overexpressing tumors with improved therapeutic efficacy. MAbs (2016) 0.75
Membrane Protein Quantity Control at the Endoplasmic Reticulum. J Membr Biol (2016) 0.75
Moderate inappropriately high aldosterone/NaCl constellation in mice: cardiovascular effects and the role of cardiovascular epidermal growth factor receptor. Sci Rep (2014) 0.75
Tanapoxvirus lacking a neuregulin-like gene regresses human melanoma tumors in nude mice. Virus Genes (2016) 0.75
Functional aspects of the EGF-induced MAP kinase cascade: a complex self-organizing system approach. PLoS One (2014) 0.75
EGFR mutations cause a lethal syndrome of epithelial dysfunction with progeroid features. Mol Genet Genomic Med (2015) 0.75
Mapping of carboxypeptidase m in normal human kidney and renal cell carcinoma: expression in tumor-associated neovasculature and macrophages. J Histochem Cytochem (2012) 0.75
EGFR inhibitor-induced skin reactions: differentiating acneiform rash from superimposed bacterial infections. Support Care Cancer (2016) 0.75
Muscle injury activates resident fibro/adipogenic progenitors that facilitate myogenesis. Nat Cell Biol (2010) 5.84
Epidermal growth factor receptor signaling synergizes with Hedgehog/GLI in oncogenic transformation via activation of the MEK/ERK/JUN pathway. Cancer Res (2009) 1.78
Epidermal EGFR controls cutaneous host defense and prevents inflammation. Sci Transl Med (2013) 1.69
Imiquimod clears tumors in mice independent of adaptive immunity by converting pDCs into tumor-killing effector cells. J Clin Invest (2012) 1.66
Identification and characterization of pDC-like cells in normal mouse skin and melanomas treated with imiquimod. J Immunol (2004) 1.39
The human HERC family of ubiquitin ligases: novel members, genomic organization, expression profiling, and evolutionary aspects. Genomics (2005) 1.36
Neuronal survival depends on EGFR signaling in cortical but not midbrain astrocytes. EMBO J (2006) 1.23
TNFalpha shedding and epidermal inflammation are controlled by Jun proteins. Genes Dev (2009) 1.04
VIGR--a novel inducible adhesion family G-protein coupled receptor in endothelial cells. FEBS Lett (2004) 1.03
Fibro/adipogenic progenitors: a double-edged sword in skeletal muscle regeneration. Cell Cycle (2010) 1.02
Divergent roles of HDAC1 and HDAC2 in the regulation of epidermal development and tumorigenesis. EMBO J (2013) 0.98
Sirolimus in renal transplant recipients with tuberous sclerosis complex: clinical effectiveness and implications for innate immunity. Transpl Int (2010) 0.96
High-affinity IgE receptors on dendritic cells exacerbate Th2-dependent inflammation. J Immunol (2011) 0.95
Nonmyogenic cells in skeletal muscle regeneration. Curr Top Dev Biol (2011) 0.92
Vildagliptin and pioglitazone in patients with impaired glucose tolerance after kidney transplantation: a randomized, placebo-controlled clinical trial. Transplantation (2013) 0.87
hVps37A Status affects prognosis and cetuximab sensitivity in ovarian cancer. Clin Cancer Res (2011) 0.84
Clinical trials for treatment of NODAT: time to collaborate. Transplantation (2012) 0.83
Fluid overload in hemodialysis patients: a cross-sectional study to determine its association with cardiac biomarkers and nutritional status. BMC Nephrol (2013) 0.81
A randomized, placebo-controlled, double-blind, prospective trial to evaluate the effect of vildagliptin in new-onset diabetes mellitus after kidney transplantation. Trials (2010) 0.79
Hereditary amyloidosis caused by R554L fibrinogen Aα-chain mutation in a Spanish family and review of the literature. Amyloid (2013) 0.75
Heart Failure with Preserved and Reduced Ejection Fraction in Hemodialysis Patients: Prevalence, Disease Prediction and Prognosis. Kidney Blood Press Res (2017) 0.75
Assessment of beta-cell function and insulin secretion in subjects that underwent renal transplantation. Conf Proc IEEE Eng Med Biol Soc (2015) 0.75
Molecular regulation of the renin-angiotensin system in haemodialysis patients. Nephrol Dial Transplant (2016) 0.75
Mouse models of nonmelanoma skin cancer. Methods Mol Biol (2015) 0.75