Published in J Am Chem Soc on November 21, 2007
Nanopore based sequence specific detection of duplex DNA for genomic profiling. Nano Lett (2010) 1.42
Strand invasion of extended, mixed-sequence B-DNA by gammaPNAs. J Am Chem Soc (2009) 1.22
Synthesis and characterization of conformationally preorganized, (R)-diethylene glycol-containing γ-peptide nucleic acids with superior hybridization properties and water solubility. J Org Chem (2011) 1.16
γ-AApeptides bind to RNA by mimicking RNA-binding proteins. Org Biomol Chem (2011) 1.06
Chiral introduction of positive charges to PNA for double-duplex invasion to versatile sequences. Nucleic Acids Res (2008) 1.03
Crystal structure of chiral gammaPNA with complementary DNA strand: insights into the stability and specificity of recognition and conformational preorganization. J Am Chem Soc (2010) 1.02
High-affinity triplex targeting of double stranded DNA using chemically modified peptide nucleic acid oligomers. Nucleic Acids Res (2009) 1.02
Strand invasion of mixed-sequence, double-helical B-DNA by γ-peptide nucleic acids containing G-clamp nucleobases under physiological conditions. Biochemistry (2011) 1.01
Invader LNA: efficient targeting of short double stranded DNA. Org Biomol Chem (2010) 1.01
Electronic barcoding of a viral gene at the single-molecule level. Nano Lett (2012) 1.00
γ Sulphate PNA (PNA S): highly selective DNA binding molecule showing promising antigene activity. PLoS One (2012) 0.86
Development of bis-locked nucleic acid (bisLNA) oligonucleotides for efficient invasion of supercoiled duplex DNA. Nucleic Acids Res (2013) 0.85
Cellular uptakes, biostabilities and anti-miR-210 activities of chiral arginine-PNAs in leukaemic K562 cells. Chembiochem (2012) 0.83
Microscopic rearrangement of bound minor groove binders detected by NMR. J Phys Chem B (2012) 0.82
Sequence specificity at targeting double-stranded DNA with a γ-PNA oligomer modified with guanidinium G-clamp nucleobases. Artif DNA PNA XNA (2010) 0.81
Evaluating the effect of ionic strength on duplex stability for PNA having negatively or positively charged side chains. PLoS One (2013) 0.81
Fluorescence imaging of single-copy DNA sequences within the human genome using PNA-directed padlock probe assembly. Chem Biol (2013) 0.81
Nanoparticle for delivery of antisense γPNA oligomers targeting CCR5. Artif DNA PNA XNA (2013) 0.80
Effect of Steric Constraint at the γ-Backbone Position on the Conformations and Hybridization Properties of PNAs. J Nucleic Acids (2011) 0.80
DNA sequencing and bar-coding using solid-state nanopores. Electrophoresis (2012) 0.79
RecA-mediated strand invasion of DNA by oligonucleotides substituted with 2-aminoadenine and 2-thiothymine. Nucleic Acids Res (2008) 0.77
Disruption of Higher Order DNA Structures in Friedreich's Ataxia (GAA)n Repeats by PNA or LNA Targeting. PLoS One (2016) 0.75
Structure and Function of AApeptides. Biochemistry (2016) 0.75
Insights on chiral, backbone modified peptide nucleic acids: Properties and biological activity. Artif DNA PNA XNA (2016) 0.75
Effect of chirality in gamma-PNA: PNA interaction, another piece in the picture. Artif DNA PNA XNA (2014) 0.75
Chemical modifications of artificial restriction DNA cutter (ARCUT) to promote its in vivo and in vitro applications. Artif DNA PNA XNA (2014) 0.75
Focus on PNA Flexibility and RNA Binding using Molecular Dynamics and Metadynamics. Sci Rep (2017) 0.75
Duplex DNA-Invading γ-Modified Peptide Nucleic Acids Enable Rapid Identification of Bloodstream Infections in Whole Blood. MBio (2016) 0.75
Synthesis of new fluorogenic cyanine dyes and incorporation into RNA fluoromodules. Org Lett (2008) 1.53
A simple gamma-backbone modification preorganizes peptide nucleic acid into a helical structure. J Am Chem Soc (2006) 1.34
A rainbow of fluoromodules: a promiscuous scFv protein binds to and activates a diverse set of fluorogenic cyanine dyes. J Am Chem Soc (2008) 1.29
Fluorescent DNA nanotags: supramolecular fluorescent labels based on intercalating dye arrays assembled on nanostructured DNA templates. J Am Chem Soc (2007) 1.26
Strand invasion of extended, mixed-sequence B-DNA by gammaPNAs. J Am Chem Soc (2009) 1.22
Synthesis and characterization of conformationally preorganized, (R)-diethylene glycol-containing γ-peptide nucleic acids with superior hybridization properties and water solubility. J Org Chem (2011) 1.16
Experimental and computational investigation of unsymmetrical cyanine dyes: understanding torsionally responsive fluorogenic dyes. J Am Chem Soc (2007) 1.16
Formation of a PNA2-DNA2 hybrid quadruplex. J Am Chem Soc (2003) 1.15
Novel binding and efficient cellular uptake of guanidine-based peptide nucleic acids (GPNA). J Am Chem Soc (2003) 1.12
DNA-templated assembly of helical cyanine dye aggregates: a supramolecular chain polymerization. Acc Chem Res (2004) 1.07
A simple cytosine to G-clamp nucleobase substitution enables chiral gamma-PNAs to invade mixed-sequence double-helical B-form DNA. Chembiochem (2008) 1.04
Improved photostability and fluorescence properties through polyfluorination of a cyanine dye. Org Lett (2004) 1.04
Fluorescent DNA nanotags based on a self-assembled DNA tetrahedron. ACS Nano (2009) 1.04
Crystal structure of chiral gammaPNA with complementary DNA strand: insights into the stability and specificity of recognition and conformational preorganization. J Am Chem Soc (2010) 1.02
High-affinity homologous peptide nucleic acid probes for targeting a quadruplex-forming sequence from a MYC promoter element. Biochemistry (2007) 1.02
RNA guanine quadruplex invasion by complementary and homologous PNA probes. J Am Chem Soc (2005) 1.01
Strand invasion of mixed-sequence, double-helical B-DNA by γ-peptide nucleic acids containing G-clamp nucleobases under physiological conditions. Biochemistry (2011) 1.01
Electronic barcoding of a viral gene at the single-molecule level. Nano Lett (2012) 1.00
Sequence-unrestricted, Watson-Crick recognition of double helical B-DNA by (R)-miniPEG-γPNAs. Chembiochem (2011) 1.00
Quadruplex formation by a guanine-rich PNA oligomer. J Am Chem Soc (2005) 1.00
Enhanced photostability of genetically encodable fluoromodules based on fluorogenic cyanine dyes and a promiscuous protein partner. J Am Chem Soc (2009) 0.99
Cell-permeable GPNA with appropriate backbone stereochemistry and spacing binds sequence-specifically to RNA. Chem Commun (Camb) (2004) 0.98
Loop and backbone modifications of peptide nucleic acid improve g-quadruplex binding selectivity. J Am Chem Soc (2009) 0.96
Hybridization of complementary and homologous peptide nucleic acid oligomers to a guanine quadruplex-forming RNA. Biochemistry (2006) 0.95
Synthesis of conformationally preorganized and cell-permeable guanidine-based gamma-peptide nucleic acids (gammaGPNAs). J Org Chem (2009) 0.95
Synthesis of cell-permeable peptide nucleic acids and characterization of their hybridization and uptake properties. Bioorg Med Chem Lett (2006) 0.95
A variable light domain fluorogen activating protein homodimerizes to activate dimethylindole red. Biochemistry (2012) 0.95
Fluorescent PNA probes as hybridization labels for biological RNA. Biochemistry (2006) 0.95
Blue fluorescent dye-protein complexes based on fluorogenic cyanine dyes and single chain antibody fragments. Org Biomol Chem (2010) 0.95
Cell-permeable peptide nucleic acid designed to bind to the 5'-untranslated region of E-cadherin transcript induces potent and sequence-specific antisense effects. J Am Chem Soc (2006) 0.93
Fluorescent DNA nanotags featuring covalently attached intercalating dyes: synthesis, antibody conjugation, and intracellular imaging. Bioconjug Chem (2011) 0.93
Twisted cyanines: a non-planar fluorogenic dye with superior photostability and its use in a protein-based fluoromodule. J Am Chem Soc (2012) 0.89
Promoter scanning of the human COX-2 gene with 8-ring polyamides: unexpected weakening of polyamide-DNA binding and selectivity by replacing an internal N-Me-pyrrole with β-alanine. Biochimie (2012) 0.88
β-Catenin knockdown in liver tumor cells by a cell permeable gamma guanidine-based peptide nucleic acid. Curr Cancer Drug Targets (2013) 0.87
Noncovalent binding and fluorogenic response of cyanine dyes to DNA homoquadruplex and PNA-DNA heteroquadruplex structures. Artif DNA PNA XNA (2011) 0.85
Fluorescence assay of polyamide-DNA interactions. Anal Biochem (2012) 0.85
Substituent effects on the assembly of helical cyanine dye aggregates in the minor groove of a DNA template. Langmuir (2010) 0.83
Effect of PNA backbone modifications on cyanine dye binding to PNA-DNA duplexes investigated by optical spectroscopy and molecular dynamics simulations. J Am Chem Soc (2005) 0.83
1H NMR and optical spectroscopic investigation of the sequence-dependent dimerization of a symmetrical cyanine dye in the DNA minor groove. Biochemistry (2005) 0.82
The structure of a gamma-modified peptide nucleic acid duplex. Mol Biosyst (2010) 0.82
Wavelength Dependence of the Fluorescence Quenching Efficiency of Nearby Dyes by Gold Nanoclusters and Nanoparticles: The Roles of Spectral Overlap and Particle Size. J Phys Chem C Nanomater Interfaces (2011) 0.81
Telomeric repeat mutagenicity in human somatic cells is modulated by repeat orientation and G-quadruplex stability. DNA Repair (Amst) (2010) 0.81
Sequence specificity at targeting double-stranded DNA with a γ-PNA oligomer modified with guanidinium G-clamp nucleobases. Artif DNA PNA XNA (2010) 0.81
Nanoparticle for delivery of antisense γPNA oligomers targeting CCR5. Artif DNA PNA XNA (2013) 0.80
Role reversal in a supramolecular assembly: a chiral cyanine dye controls the helicity of a peptide-nucleic acid duplex. Langmuir (2005) 0.80
Effect of Steric Constraint at the γ-Backbone Position on the Conformations and Hybridization Properties of PNAs. J Nucleic Acids (2011) 0.80
Single-stranded γPNAs for in vivo site-specific genome editing via Watson-Crick recognition. Curr Gene Ther (2014) 0.79
Kinetic discrimination in recognition of DNA quadruplex targets by guanine-rich heteroquadruplex-forming PNA probes. Chem Commun (Camb) (2011) 0.79
Effect of backbone flexibility on charge transfer rates in peptide nucleic acid duplexes. J Am Chem Soc (2012) 0.79
Recent advances in the development of peptide nucleic acid as a gene-targeted drug. Expert Opin Biol Ther (2004) 0.78
Antitumor effects of EGFR antisense guanidine-based peptide nucleic acids in cancer models. ACS Chem Biol (2012) 0.78
Coordination-driven inversion of handedness in ligand-modified PNA. Inorg Chem (2011) 0.78
Molecular engineering of torsional potentials in fluorogenic dyes via electronic substituent effects. J Phys Chem A (2008) 0.78
Bichromophoric dyes for wavelength shifting of dye-protein fluoromodules. Org Biomol Chem (2015) 0.77
Antigene leaps forward through an open door. Nat Chem Biol (2005) 0.77
Colorimetric detection of PNA-DNA hybridization using cyanine dyes. Methods Mol Biol (2002) 0.77
Label-free molecular beacons for biomolecular detection. Anal Chem (2014) 0.77
A single-chain-variable-fragment fluorescence biosensor activates fluorogens from dissimilar chemical families. Protein Pept Lett (2014) 0.77
Hybridization of G-quadruplex-forming peptide nucleic acids to guanine-rich DNA templates inhibits DNA polymerase η extension. Biochemistry (2014) 0.76
RTD-1mimic containing γPNA scaffold exhibits broad-spectrum antibacterial activities. J Am Chem Soc (2012) 0.76
Aptamers act as activators for the thrombin mediated-hydrolysis of peptide substrates. Chembiochem (2013) 0.76
Synthesis and characterization of thermoreversible biopolymer microgels based on hydrogen bonded nucleobase pairing. J Am Chem Soc (2003) 0.76
Strand invasion of DNA quadruplexes by PNA: comparison of homologous and complementary hybridization. Chembiochem (2013) 0.76
High affinity γPNA sandwich hybridization assay for rapid detection of short nucleic acid targets with single mismatch discrimination. Biomacromolecules (2013) 0.75
Spectral fine tuning of cyanine dyes: electron donor-acceptor substituted analogues of thiazole orange. Photochem Photobiol Sci (2015) 0.75
The rule of four. Nat Chem Biol (2007) 0.75
Correction to "Silver Nanoassemblies Constructed from Boranephosphonate DNA". J Am Chem Soc (2017) 0.75
Embryonic stem cells: a perfect marriage between gene regulation and regenerative medicine. Curr Top Med Chem (2003) 0.75
MiniPEG-γPNA. Methods Mol Biol (2014) 0.75
A recoverable enzymatic microgel based on biomolecular recognition. J Am Chem Soc (2004) 0.75
Corrections to "Pyridinium Boranephosphonate Modified DNA Oligonucleotides". J Org Chem (2017) 0.75
Correction to "Oxidative Substitution of Boranephosphonate Diesters as a Route to Post-synthetically Modified DNA". J Am Chem Soc (2015) 0.75
Oxidative substitution of boranephosphonate diesters as a route to post-synthetically modified DNA. J Am Chem Soc (2015) 0.75
Correction to "Oxidative Substitution of Boranephosphonate Diesters as a Route to Post-synthetically Modified DNA". J Am Chem Soc (2017) 0.75