Published in J Am Chem Soc on June 11, 2003
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β-Catenin knockdown in liver tumor cells by a cell permeable gamma guanidine-based peptide nucleic acid. Curr Cancer Drug Targets (2013) 0.87
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Self-assembled antibody multimers through peptide nucleic acid conjugation. J Am Chem Soc (2012) 0.86
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Evaluating the effect of ionic strength on duplex stability for PNA having negatively or positively charged side chains. PLoS One (2013) 0.81
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Antitumor effects of EGFR antisense guanidine-based peptide nucleic acids in cancer models. ACS Chem Biol (2012) 0.78
Toward the Ideal Synthesis and Transformative Therapies: The Roles of Step Economy and Function Oriented Synthesis. Tetrahedron (2013) 0.78
Targeting pre-miRNA by peptide nucleic acids: a new strategy to interfere in the miRNA maturation. Artif DNA PNA XNA (2012) 0.77
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Improvement of sequence selectivity in triple helical recognition of RNA by phenylalanine-derived PNA. Artif DNA PNA XNA (2013) 0.75
Incorporating a guanidine-modified cytosine base into triplex-forming PNAs for the recognition of a C-G pyrimidine-purine inversion site of an RNA duplex. Nucleic Acids Res (2016) 0.75
Dual-targeted peptide-conjugated multifunctional fluorescent probe with AIEgen for efficient nucleus-specific imaging and long-term tracing of cancer cells. Chem Sci (2017) 0.75
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Paired-end mapping reveals extensive structural variation in the human genome. Science (2007) 30.46
Recommendations for evaluation of the severity of native valvular regurgitation with two-dimensional and Doppler echocardiography. J Am Soc Echocardiogr (2003) 11.88
A new arenavirus in a cluster of fatal transplant-associated diseases. N Engl J Med (2008) 7.73
Recommendations for quantification of Doppler echocardiography: a report from the Doppler Quantification Task Force of the Nomenclature and Standards Committee of the American Society of Echocardiography. J Am Soc Echocardiogr (2002) 7.59
Analysis of one million base pairs of Neanderthal DNA. Nature (2006) 6.17
Unique features of a highly pathogenic Campylobacter jejuni strain. Infect Immun (2006) 5.21
Transcriptome sequencing of malignant pleural mesothelioma tumors. Proc Natl Acad Sci U S A (2008) 4.75
Multiplex sequencing of paired-end ditags (MS-PET): a strategy for the ultra-high-throughput analysis of transcriptomes and genomes. Nucleic Acids Res (2006) 4.51
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Fluorogen-activating single-chain antibodies for imaging cell surface proteins. Nat Biotechnol (2007) 2.45
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Parkin ubiquitinates Drp1 for proteasome-dependent degradation: implication of dysregulated mitochondrial dynamics in Parkinson disease. J Biol Chem (2011) 1.75
Genomic characterization of the Yersinia genus. Genome Biol (2010) 1.63
P53 codon 72 polymorphism contributes to breast cancer risk: a meta-analysis based on 39 case-control studies. Breast Cancer Res Treat (2009) 1.61
Discovery of regulators of receptor internalization with high-throughput flow cytometry. Mol Pharmacol (2012) 1.61
Genome sequence of Brucella abortus vaccine strain S19 compared to virulent strains yields candidate virulence genes. PLoS One (2008) 1.57
The genetic basis of laboratory adaptation in Caulobacter crescentus. J Bacteriol (2010) 1.45
Genomic characterization of the Bacillus cereus sensu lato species: backdrop to the evolution of Bacillus anthracis. Genome Res (2012) 1.37
Microenvironments engineered by inkjet bioprinting spatially direct adult stem cells toward muscle- and bone-like subpopulations. Stem Cells (2007) 1.37
A simple gamma-backbone modification preorganizes peptide nucleic acid into a helical structure. J Am Chem Soc (2006) 1.34
Strand invasion of mixed-sequence B-DNA by acridine-linked, gamma-peptide nucleic acid (gamma-PNA). J Am Chem Soc (2007) 1.34
A robust hybrid between genetic algorithm and support vector machine for extracting an optimal feature gene subset. Genomics (2005) 1.30
Fluorescent DNA nanotags: supramolecular fluorescent labels based on intercalating dye arrays assembled on nanostructured DNA templates. J Am Chem Soc (2007) 1.26
Strand invasion of extended, mixed-sequence B-DNA by gammaPNAs. J Am Chem Soc (2009) 1.22
Discovery of Time-Delayed Gene Regulatory Networks based on temporal gene expression profiling. BMC Bioinformatics (2006) 1.18
Fluorogen-activating proteins as biosensors of cell-surface proteins in living cells. Cytometry A (2010) 1.17
Synthesis and characterization of conformationally preorganized, (R)-diethylene glycol-containing γ-peptide nucleic acids with superior hybridization properties and water solubility. J Org Chem (2011) 1.16
Therapeutic effect of human umbilical cord multipotent mesenchymal stromal cells in a rat model of stroke. Transplantation (2009) 1.16
Whole-genome sequencing reveals a link between β-lactam resistance and synthetases of the alarmone (p)ppGpp in Staphylococcus aureus. Microb Drug Resist (2013) 1.14
Roscovitine binds to novel L-channel (CaV1.2) sites that separately affect activation and inactivation. J Biol Chem (2009) 1.08
Constructing disease-specific gene networks using pair-wise relevance metric: application to colon cancer identifies interleukin 8, desmin and enolase 1 as the central elements. BMC Syst Biol (2008) 1.08
Engineered spatial patterns of FGF-2 immobilized on fibrin direct cell organization. Biomaterials (2005) 1.07
Therapeutic benefit of human umbilical cord derived mesenchymal stromal cells in intracerebral hemorrhage rat: implications of anti-inflammation and angiogenesis. Cell Physiol Biochem (2009) 1.04
A simple cytosine to G-clamp nucleobase substitution enables chiral gamma-PNAs to invade mixed-sequence double-helical B-form DNA. Chembiochem (2008) 1.04
Common genetic variants on 8q24 contribute to susceptibility to bladder cancer in a Chinese population. Carcinogenesis (2009) 1.03
Dose-dependent cell growth in response to concentration modulated patterns of FGF-2 printed on fibrin. Biomaterials (2005) 1.03
High-affinity homologous peptide nucleic acid probes for targeting a quadruplex-forming sequence from a MYC promoter element. Biochemistry (2007) 1.02
The DNA repair gene APE1 T1349G polymorphism and cancer risk: a meta-analysis of 27 case-control studies. Mutagenesis (2009) 1.02
Crystal structure of chiral gammaPNA with complementary DNA strand: insights into the stability and specificity of recognition and conformational preorganization. J Am Chem Soc (2010) 1.02
Strand invasion of mixed-sequence, double-helical B-DNA by γ-peptide nucleic acids containing G-clamp nucleobases under physiological conditions. Biochemistry (2011) 1.01
A novel structure-aware sparse learning algorithm for brain imaging genetics. Med Image Comput Comput Assist Interv (2014) 1.01
Electronic barcoding of a viral gene at the single-molecule level. Nano Lett (2012) 1.00
Sequence-unrestricted, Watson-Crick recognition of double helical B-DNA by (R)-miniPEG-γPNAs. Chembiochem (2011) 1.00
The effects of a high-fat, high-fructose, and combination diet on learning, weight, and glucose regulation in C57BL/6 mice. Behav Brain Res (2006) 0.98
Cell-permeable GPNA with appropriate backbone stereochemistry and spacing binds sequence-specifically to RNA. Chem Commun (Camb) (2004) 0.98
Reciprocal interactions between tumor-associated macrophages and CD44-positive cancer cells via osteopontin/CD44 promote tumorigenicity in colorectal cancer. Clin Cancer Res (2012) 0.97
Carbonized nanoscale metal-organic frameworks as high performance electrocatalyst for oxygen reduction reaction. ACS Nano (2014) 0.96
Loop and backbone modifications of peptide nucleic acid improve g-quadruplex binding selectivity. J Am Chem Soc (2009) 0.96
Noninvasive dynamic fluorescence imaging of human melanomas reveals that targeted inhibition of bFGF or FGFR-1 in melanoma cells blocks tumor growth by apoptosis. Mol Med (2002) 0.95
Successful sleeve lobectomy of inflammatory myofibroblastic tumor in a 4-year-old child. Ann Thorac Cardiovasc Surg (2013) 0.95
Synthesis of conformationally preorganized and cell-permeable guanidine-based gamma-peptide nucleic acids (gammaGPNAs). J Org Chem (2009) 0.95
Synthesis of cell-permeable peptide nucleic acids and characterization of their hybridization and uptake properties. Bioorg Med Chem Lett (2006) 0.95
Alcohol consumption and carotid atherosclerosis in China: the Cardiovascular Risk Survey. Eur J Prev Cardiol (2011) 0.94
Cell-permeable peptide nucleic acid designed to bind to the 5'-untranslated region of E-cadherin transcript induces potent and sequence-specific antisense effects. J Am Chem Soc (2006) 0.93
Nitric oxide signaling in stretch-induced apoptosis of neonatal rat cardiomyocytes. FASEB J (2006) 0.92
Integrated lipase production and in situ biodiesel synthesis in a recombinant Pichia pastoris yeast: an efficient dual biocatalytic system composed of cell free enzymes and whole cell catalysts. Biotechnol Biofuels (2014) 0.92
Inkjet printing of growth factor concentration gradients and combinatorial arrays immobilized on biologically-relevant substrates. Comb Chem High Throughput Screen (2009) 0.92
Fluorogen activating proteins in flow cytometry for the study of surface molecules and receptors. Methods (2012) 0.92
Insulin resistance predicts endothelial dysfunction and cardiovascular risk in HIV-infected persons on long-term highly active antiretroviral therapy. AIDS (2008) 0.91
Isolated hepatobiliary cryptococcosis manifesting as obstructive jaundice in an immunocompetent child: case report and review of the literature. Eur J Pediatr (2013) 0.91
Improved oral bioavailability of capsaicin via liposomal nanoformulation: preparation, in vitro drug release and pharmacokinetics in rats. Arch Pharm Res (2014) 0.91
Extraction, purification and characterization of polysaccharides from Hawk tea. Carbohydr Polym (2013) 0.91
Targeted expression of uncoupling protein 2 to mouse liver increases the susceptibility to lipopolysaccharide/galactosamine-induced acute liver injury. Hepatology (2009) 0.91
Prognostic significance of hypothalamic-pituitary-adrenal axis hormones in early sepsis: a study performed in the emergency department. Intensive Care Med (2014) 0.91
Establishment of a human colorectal cancer cell line P6C with stem cell properties and resistance to chemotherapeutic drugs. Acta Pharmacol Sin (2013) 0.90
The MPO -463G>A polymorphism and cancer risk: a meta-analysis based on 43 case-control studies. Mutagenesis (2010) 0.88
High-throughput flow cytometry compatible biosensor based on fluorogen activating protein technology. Cytometry A (2013) 0.88
Mannitol-adenine-phosphate: a novel solution for intraoperative blood salvage. Transfusion (2013) 0.87
β-Catenin knockdown in liver tumor cells by a cell permeable gamma guanidine-based peptide nucleic acid. Curr Cancer Drug Targets (2013) 0.87
Macrophage migration inhibitory factor gene -173G>C polymorphism and risk of bladder cancer in southeast China: a case-control analysis. Mol Biol Rep (2011) 0.87
Cyclin D1 G870A polymorphism is associated with risk and clinicopathologic characteristics of bladder cancer. DNA Cell Biol (2010) 0.86
Polymorphisms of methylenetetrahydrofolate reductase and methionine synthase genes and bladder cancer risk: a case-control study with meta-analysis. Clin Exp Med (2008) 0.85
Which is better to preserve pulmonary function: short-term or prolonged leukocyte depletion during cardiopulmonary bypass? J Thorac Cardiovasc Surg (2009) 0.84
Genetic variants in the death receptor 4 gene contribute to susceptibility to bladder cancer. Mutat Res (2008) 0.84
Disruption of interstitial cells of Cajal networks after massive small bowel resection. World J Gastroenterol (2013) 0.84
MicroRNA-132 enhances transition from inflammation to proliferation during wound healing. J Clin Invest (2015) 0.83
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(-)-Epigallocatechin gallate protects against cerebral ischemia-induced oxidative stress via Nrf2/ARE signaling. Neurochem Res (2014) 0.83
A systematic method for mapping multiple loci: an application to construct a genetic network for rheumatoid arthritis. Gene (2007) 0.83
The structure of a gamma-modified peptide nucleic acid duplex. Mol Biosyst (2010) 0.82
Calcicludine binding to the outer pore of L-type calcium channels is allosterically coupled to dihydropyridine binding. Biochemistry (2007) 0.82
Early and marked up-regulation of TNF-α in acute respiratory distress syndrome after cardiopulmonary bypass. Front Med (2012) 0.82
[Current status of primary hypertension in Xinjiang:an epidemiological study of Han, Uygur and Hazakh populations]. Zhonghua Yi Xue Za Zhi (2010) 0.81
CCND1 G870A polymorphism and cervical cancer risk: a case-control study and meta-analysis. J Cancer Res Clin Oncol (2010) 0.81
Threonine 32 (Thr32) of FoxO3 is critical for TGF-β-induced apoptosis via Bim in hepatocarcinoma cells. Protein Cell (2014) 0.81
The use of quantum dots for analysis of chick CAM vasculature. Microvasc Res (2006) 0.81
Sequence specificity at targeting double-stranded DNA with a γ-PNA oligomer modified with guanidinium G-clamp nucleobases. Artif DNA PNA XNA (2010) 0.81
Predicting caspase substrate cleavage sites based on a hybrid SVM-PSSM method. Protein Pept Lett (2010) 0.81
Effect of Steric Constraint at the γ-Backbone Position on the Conformations and Hybridization Properties of PNAs. J Nucleic Acids (2011) 0.80
Palmitate induces TRB3 expression and promotes apoptosis in human liver cells. Cell Physiol Biochem (2014) 0.80
The role of NQO1 polymorphisms in the susceptibility and chemotherapy response of Chinese NSCLC patients. Cell Biochem Biophys (2014) 0.80
Nanoparticle for delivery of antisense γPNA oligomers targeting CCR5. Artif DNA PNA XNA (2013) 0.80
[The relationship among CT appearances and dynamic enhancement and microvessel density of peripheral lung cancer]. Zhongguo Fei Ai Za Zhi (2003) 0.80
Blood hibernation: a novel strategy to inhibit systemic inflammation and coagulation induced by cardiopulmonary bypass. Chin Med J (Engl) (2010) 0.80
Morphological changes of Fusarium oxysporum induced by CF66I, an antifungal compound from Burkholderia cepacia. Biotechnol Lett (2010) 0.79
Kinetic discrimination in recognition of DNA quadruplex targets by guanine-rich heteroquadruplex-forming PNA probes. Chem Commun (Camb) (2011) 0.79