Published in Chembiochem on December 01, 2011
Identification and characterization of second-generation invader locked nucleic acids (LNAs) for mixed-sequence recognition of double-stranded DNA. J Org Chem (2013) 0.91
Invaders: Recognition of Double-Stranded DNA by Using Duplexes Modified with Interstrand Zippers of 2'-O-(Pyren-1-yl)methyl-ribonucleotides. Chembiochem (2013) 0.87
In vivo correction of anaemia in β-thalassemic mice by γPNA-mediated gene editing with nanoparticle delivery. Nat Commun (2016) 0.86
Recognition of mixed-sequence DNA duplexes: design guidelines for invaders based on 2'-O-(pyren-1-yl)methyl-RNA monomers. J Org Chem (2013) 0.84
Recognition of double-stranded DNA using energetically activated duplexes with interstrand zippers of 1-, 2- or 4-pyrenyl-functionalized O2'-alkylated RNA monomers. Org Biomol Chem (2014) 0.83
Nanoparticle for delivery of antisense γPNA oligomers targeting CCR5. Artif DNA PNA XNA (2013) 0.80
Invader probes: Harnessing the energy of intercalation to facilitate recognition of chromosomal DNA for diagnostic applications. Chem Sci (2015) 0.80
Single-stranded γPNAs for in vivo site-specific genome editing via Watson-Crick recognition. Curr Gene Ther (2014) 0.79
Cooperative hybridization of γPNA miniprobes to a repeating sequence motif and application to telomere analysis. Org Biomol Chem (2014) 0.77
Nanotechnology for delivery of peptide nucleic acids (PNAs). J Control Release (2016) 0.77
Synthesis and characterization of oligodeoxyribonucleotides modified with 2'-thio-2'-deoxy-2'-S-(pyren-1-yl)methyluridine. Bioorg Med Chem Lett (2015) 0.76
Bulged Invader probes: activated duplexes for mixed-sequence dsDNA recognition with improved thermodynamic and kinetic profiles. Chem Commun (Camb) (2015) 0.76
Merging Two Strategies for Mixed-Sequence Recognition of Double-Stranded DNA: Pseudocomplementary Invader Probes. J Org Chem (2016) 0.75
Targeted genome modification via triple helix formation. Methods Mol Biol (2014) 0.75
Duplex DNA-Invading γ-Modified Peptide Nucleic Acids Enable Rapid Identification of Bloodstream Infections in Whole Blood. MBio (2016) 0.75
Insights on chiral, backbone modified peptide nucleic acids: Properties and biological activity. Artif DNA PNA XNA (2016) 0.75
First-in-human trial of a STAT3 decoy oligonucleotide in head and neck tumors: implications for cancer therapy. Cancer Discov (2012) 2.31
A simple gamma-backbone modification preorganizes peptide nucleic acid into a helical structure. J Am Chem Soc (2006) 1.34
Strand invasion of mixed-sequence B-DNA by acridine-linked, gamma-peptide nucleic acid (gamma-PNA). J Am Chem Soc (2007) 1.34
Strand invasion of extended, mixed-sequence B-DNA by gammaPNAs. J Am Chem Soc (2009) 1.22
Synthesis and characterization of conformationally preorganized, (R)-diethylene glycol-containing γ-peptide nucleic acids with superior hybridization properties and water solubility. J Org Chem (2011) 1.16
Novel binding and efficient cellular uptake of guanidine-based peptide nucleic acids (GPNA). J Am Chem Soc (2003) 1.12
A simple cytosine to G-clamp nucleobase substitution enables chiral gamma-PNAs to invade mixed-sequence double-helical B-form DNA. Chembiochem (2008) 1.04
High-affinity homologous peptide nucleic acid probes for targeting a quadruplex-forming sequence from a MYC promoter element. Biochemistry (2007) 1.02
Crystal structure of chiral gammaPNA with complementary DNA strand: insights into the stability and specificity of recognition and conformational preorganization. J Am Chem Soc (2010) 1.02
Strand invasion of mixed-sequence, double-helical B-DNA by γ-peptide nucleic acids containing G-clamp nucleobases under physiological conditions. Biochemistry (2011) 1.01
Electronic barcoding of a viral gene at the single-molecule level. Nano Lett (2012) 1.00
Cell-permeable GPNA with appropriate backbone stereochemistry and spacing binds sequence-specifically to RNA. Chem Commun (Camb) (2004) 0.98
Loop and backbone modifications of peptide nucleic acid improve g-quadruplex binding selectivity. J Am Chem Soc (2009) 0.96
Synthesis of cell-permeable peptide nucleic acids and characterization of their hybridization and uptake properties. Bioorg Med Chem Lett (2006) 0.95
Synthesis of conformationally preorganized and cell-permeable guanidine-based gamma-peptide nucleic acids (gammaGPNAs). J Org Chem (2009) 0.95
Cell-permeable peptide nucleic acid designed to bind to the 5'-untranslated region of E-cadherin transcript induces potent and sequence-specific antisense effects. J Am Chem Soc (2006) 0.93
β-Catenin knockdown in liver tumor cells by a cell permeable gamma guanidine-based peptide nucleic acid. Curr Cancer Drug Targets (2013) 0.87
The effect of cilostazol on stent thrombosis after drug-eluting stent implantation. Korean Circ J (2010) 0.85
The structure of a gamma-modified peptide nucleic acid duplex. Mol Biosyst (2010) 0.82
Development of novel inhibitors targeting HIF-1α towards anticancer drug discovery. Bioorg Med Chem Lett (2010) 0.81
Sequence specificity at targeting double-stranded DNA with a γ-PNA oligomer modified with guanidinium G-clamp nucleobases. Artif DNA PNA XNA (2010) 0.81
Nanoparticle for delivery of antisense γPNA oligomers targeting CCR5. Artif DNA PNA XNA (2013) 0.80
Effect of Steric Constraint at the γ-Backbone Position on the Conformations and Hybridization Properties of PNAs. J Nucleic Acids (2011) 0.80
P7170, a novel inhibitor of mTORC1/mTORC2 and Activin receptor-like Kinase 1 (ALK1) inhibits the growth of non small cell lung cancer. Mol Cancer (2014) 0.80
Single-stranded γPNAs for in vivo site-specific genome editing via Watson-Crick recognition. Curr Gene Ther (2014) 0.79
Kinetic discrimination in recognition of DNA quadruplex targets by guanine-rich heteroquadruplex-forming PNA probes. Chem Commun (Camb) (2011) 0.79
Effect of backbone flexibility on charge transfer rates in peptide nucleic acid duplexes. J Am Chem Soc (2012) 0.79
Coordination-driven inversion of handedness in ligand-modified PNA. Inorg Chem (2011) 0.78
Antitumor effects of EGFR antisense guanidine-based peptide nucleic acids in cancer models. ACS Chem Biol (2012) 0.78
RTD-1mimic containing γPNA scaffold exhibits broad-spectrum antibacterial activities. J Am Chem Soc (2012) 0.76
Strand invasion of DNA quadruplexes by PNA: comparison of homologous and complementary hybridization. Chembiochem (2013) 0.76
High affinity γPNA sandwich hybridization assay for rapid detection of short nucleic acid targets with single mismatch discrimination. Biomacromolecules (2013) 0.75
MiniPEG-γPNA. Methods Mol Biol (2014) 0.75
Embryonic stem cells: a perfect marriage between gene regulation and regenerative medicine. Curr Top Med Chem (2003) 0.75