Published in Br J Nutr on December 06, 2007
Plasma vitamins B2, B6, and B12, and related genetic variants as predictors of colorectal cancer risk. Cancer Epidemiol Biomarkers Prev (2010) 1.05
Meta- and pooled analyses of the methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism and colorectal cancer: a HuGE-GSEC review. Am J Epidemiol (2009) 1.05
Association of polymorphisms MTHFR C677T and A1298C with risk of colorectal cancer, genetic and epigenetic characteristic of tumors, and response to chemotherapy. Int J Colorectal Dis (2009) 1.04
Germline polymorphisms in the one-carbon metabolism pathway and DNA methylation in colorectal cancer. Cancer Causes Control (2010) 1.04
Genetic variability in the MTHFR gene and colorectal cancer risk using the colorectal cancer family registry. Cancer Epidemiol Biomarkers Prev (2010) 1.03
A candidate gene study of folate-associated one carbon metabolism genes and colorectal cancer risk. Cancer Epidemiol Biomarkers Prev (2010) 0.99
Folate Intake, MTHFR Polymorphisms, and the Risk of Colorectal Cancer: A Systematic Review and Meta-Analysis. J Cancer Epidemiol (2012) 0.95
The 677C>T (rs1801133) polymorphism in the MTHFR gene contributes to colorectal cancer risk: a meta-analysis based on 71 research studies. PLoS One (2013) 0.93
Association of methylenetetrahydrofolate reductase C677T and A1298C polymorphisms with colorectal cancer risk: A meta-analysis. Biomed Rep (2013) 0.92
Folate and colorectal cancer prevention. Br J Cancer (2008) 0.89
The polymorphisms in methylenetetrahydrofolate reductase, methionine synthase, methionine synthase reductase, and the risk of colorectal cancer. Int J Biol Sci (2012) 0.85
Dietary B vitamin and methionine intakes and plasma folate are not associated with colorectal cancer risk in Chinese women. Cancer Epidemiol Biomarkers Prev (2009) 0.82
Systemic folate status, rectal mucosal folate concentration and dietary intake in patients at differential risk of bowel cancer (The FAB2 Study). Eur J Nutr (2012) 0.78
Risk factors for colon cancer in Northeastern Thailand: interaction of MTHFR codon 677 and 1298 genotypes with environmental factors. J Epidemiol (2010) 0.76
Vitamin B2 intake and colorectal cancer risk; results from the Nurses' Health Study and the Health Professionals Follow-Up Study cohort. Int J Cancer (2016) 0.75
Genome-wide association studies for complex traits: consensus, uncertainty and challenges. Nat Rev Genet (2008) 30.94
Bevacizumab in combination with oxaliplatin-based chemotherapy as first-line therapy in metastatic colorectal cancer: a randomized phase III study. J Clin Oncol (2008) 15.17
Capecitabine as adjuvant treatment for stage III colon cancer. N Engl J Med (2005) 6.22
Assessment of cumulative evidence on genetic associations: interim guidelines. Int J Epidemiol (2007) 4.96
Size matters: just how big is BIG?: Quantifying realistic sample size requirements for human genome epidemiology. Int J Epidemiol (2008) 4.53
How many genes underlie the occurrence of common complex diseases in the population? Int J Epidemiol (2005) 4.46
Cleft lip and palate. Lancet (2009) 4.29
Disruption of an AP-2alpha binding site in an IRF6 enhancer is associated with cleft lip. Nat Genet (2008) 4.04
A road map for efficient and reliable human genome epidemiology. Nat Genet (2006) 3.21
Daily soluble aspirin and prevention of colorectal adenoma recurrence: one-year results of the APACC trial. Gastroenterology (2003) 2.96
On the synthesis and interpretation of consistent but weak gene-disease associations in the era of genome-wide association studies. Int J Epidemiol (2006) 2.66
Quality, quantity and harmony: the DataSHaPER approach to integrating data across bioclinical studies. Int J Epidemiol (2010) 2.44
DataSHIELD: resolving a conflict in contemporary bioscience--performing a pooled analysis of individual-level data without sharing the data. Int J Epidemiol (2010) 2.23
A randomized trial comparing treatments for varicose veins. N Engl J Med (2014) 2.20
Disease course patterns after discontinuation of bevacizumab: pooled analysis of randomized phase III trials. J Clin Oncol (2010) 2.19
Genome-wide association studies, field synopses, and the development of the knowledge base on genetic variation and human diseases. Am J Epidemiol (2009) 2.15
Potential regional differences for the tolerability profiles of fluoropyrimidines. J Clin Oncol (2008) 1.92
Polymorphisms in genes involved in folate metabolism and colorectal neoplasia: a HuGE review. Am J Epidemiol (2004) 1.91
Vitamin D status of Canadians as measured in the 2007 to 2009 Canadian Health Measures Survey. Health Rep (2010) 1.75
Systematic review: family history in risk assessment for common diseases. Ann Intern Med (2009) 1.70
Physical activity and postmenopausal breast cancer: proposed biologic mechanisms and areas for future research. Cancer Epidemiol Biomarkers Prev (2009) 1.67
Efficacy of oxaliplatin plus capecitabine or infusional fluorouracil/leucovorin in patients with metastatic colorectal cancer: a pooled analysis of randomized trials. J Clin Oncol (2008) 1.65
The emergence of networks in human genome epidemiology: challenges and opportunities. Epidemiology (2007) 1.61
Systematic reviews of genetic association studies. Human Genome Epidemiology Network. PLoS Med (2009) 1.60
An epidemiologic assessment of genomic profiling for measuring susceptibility to common diseases and targeting interventions. Genet Med (2004) 1.57
Occupational risk factors for low grade and high grade glioma: results from an international case control study of adult brain tumours. Int J Cancer (2005) 1.54
Citizens' values regarding research with stored samples from newborn screening in Canada. Pediatrics (2012) 1.48
Addressing the challenges of cleft lip and palate research in India. Indian J Plast Surg (2009) 1.46
Strengthening the reporting of Genetic RIsk Prediction Studies (GRIPS): explanation and elaboration. J Clin Epidemiol (2011) 1.46
A network of investigator networks in human genome epidemiology. Am J Epidemiol (2005) 1.43
Is rigorous retrospective harmonization possible? Application of the DataSHaPER approach across 53 large studies. Int J Epidemiol (2011) 1.41
Folate intake, markers of folate status and oral clefts: is the evidence converging? Int J Epidemiol (2008) 1.37
The emergence of epidemiology in the genomics age. Int J Epidemiol (2004) 1.36
Striking the right balance in colorectal cancer care--a qualitative study of rural and urban patients. Fam Pract (2002) 1.30
Systematic meta-analyses and field synopsis of genetic association studies in colorectal cancer. J Natl Cancer Inst (2012) 1.30
A P3G generic access agreement for population genomic studies. Nat Biotechnol (2013) 1.28
Effect of renal impairment on the pharmacokinetics and tolerability of capecitabine (Xeloda) in cancer patients. Cancer Chemother Pharmacol (2002) 1.26
Methods for meta-analyses of genome-wide association studies: critical assessment of empirical evidence. Am J Epidemiol (2012) 1.24
Understanding sickle cell carrier status identified through newborn screening: a qualitative study. Eur J Hum Genet (2009) 1.22
After-effects reported by women following colposcopy, cervical biopsies and LLETZ: results from the TOMBOLA trial. BJOG (2009) 1.21
Family history and improving health. Evid Rep Technol Assess (Full Rep) (2009) 1.17
Dietary patterns of school-age children in Scotland: association with socio-economic indicators, physical activity and obesity. Br J Nutr (2009) 1.17
Analysis of key cell-cycle checkpoint proteins in colorectal tumours. J Pathol (2002) 1.17
Associations between two common variants C677T and A1298C in the methylenetetrahydrofolate reductase gene and measures of folate metabolism and DNA stability (strand breaks, misincorporated uracil, and DNA methylation status) in human lymphocytes in vivo. Cancer Epidemiol Biomarkers Prev (2004) 1.11
MC1R variants increased the risk of sporadic cutaneous melanoma in darker-pigmented Caucasians: a pooled-analysis from the M-SKIP project. Int J Cancer (2014) 1.10
Strengthening the reporting of Genetic RIsk Prediction Studies: the GRIPS Statement. PLoS Med (2011) 1.09
The human genome project is complete. How do we develop a handle for the pump? Am J Epidemiol (2003) 1.07
The role of cytokine gene polymorphisms in colorectal cancer and their interaction with aspirin use in the northeast of Scotland. Cancer Epidemiol Biomarkers Prev (2005) 1.06
Colorectal cancer and genetic polymorphisms of CYP1A1, GSTM1 and GSTT1: a case-control study in the Grampian region of Scotland. Int J Cancer (2006) 1.05
Trial of management of borderline and other low-grade abnormal smears (TOMBOLA): Trial design. Contemp Clin Trials (2006) 1.05
Prognostic significance of p16 in locally advanced squamous cell carcinoma of the head and neck treated with concurrent cisplatin and radiotherapy. Head Neck (2011) 1.05
Strengthening the reporting of genetic risk prediction studies: the GRIPS statement. Eur J Epidemiol (2011) 1.04
Head and neck cancer: from anatomy to biology. Int J Cancer (2013) 1.04
Achieving the "triple aim" for inborn errors of metabolism: a review of challenges to outcomes research and presentation of a new practice-based evidence framework. Genet Med (2012) 1.04
Turning the pump handle: evolving methods for integrating the evidence on gene-disease association. Am J Epidemiol (2007) 1.01
Variability in the clinical management of fatty acid oxidation disorders: results of a survey of Canadian metabolic physicians. J Inherit Metab Dis (2011) 1.01
Dietary flavonoid intake and colorectal cancer: a case-control study. Br J Nutr (2009) 0.99
The utility and predictive value of combinations of low penetrance genes for screening and risk prediction of colorectal cancer. Hum Genet (2010) 0.99
Enclosing a pen with a postal questionnaire can significantly increase the response rate. J Clin Epidemiol (2006) 0.99
Cohorts and consortia conference: a summary report (Banff, Canada, June 17-19, 2009). Cancer Causes Control (2011) 0.99
Recommendations and proposed guidelines for assessing the cumulative evidence on joint effects of genes and environments on cancer occurrence in humans. Int J Epidemiol (2012) 0.99
Effect of a tomato-rich diet on markers of cardiovascular disease risk in moderately overweight, disease-free, middle-aged adults: a randomized controlled trial. Am J Clin Nutr (2012) 0.98
Informing parents about expanded newborn screening: influences on provider involvement. Pediatrics (2009) 0.97
Cancer risk in children and adolescents with birth defects: a population-based cohort study. PLoS One (2013) 0.96
Significant effect of capecitabine on the pharmacokinetics and pharmacodynamics of warfarin in patients with cancer. J Clin Oncol (2005) 0.96
A qualitative study of provider perspectives of structural barriers to cervical cancer screening among first nations women. Womens Health Issues (2013) 0.95
Cyclooxygenase-2 expression and recurrence of colorectal adenomas: effect of aspirin chemoprevention. Gut (2010) 0.95
United Kingdom cervical cancer screening and the costs of time and travel. Int J Technol Assess Health Care (2007) 0.95
Health-care providers' views on pursuing reproductive benefit through newborn screening: the case of sickle cell disorders. Eur J Hum Genet (2011) 0.95
Strengthening the reporting of genetic risk prediction studies (GRIPS): explanation and elaboration. Eur J Epidemiol (2011) 0.94
Current status of cediranib: the rapid development of a novel anti-angiogenic therapy. Future Oncol (2009) 0.94
Fetal anticonvulsant syndromes and polymorphisms in MTHFR, MTR, and MTRR. Am J Med Genet A (2007) 0.93
Capecitabine/oxaliplatin, a safe and active first-line regimen for older patients with metastatic colorectal cancer: post hoc analysis of a large phase II study. Clin Colorectal Cancer (2005) 0.93
The unintended consequences of cervical screening: distress in women undergoing cytologic surveillance. J Low Genit Tract Dis (2014) 0.92
Bias in the case-only design applied to studies of gene-environment and gene-gene interaction: a systematic review and meta-analysis. Int J Epidemiol (2011) 0.91
Clinical utility of cancer family history collection in primary care. Evid Rep Technol Assess (Full Rep) (2009) 0.91
Strengthening the reporting of genetic risk prediction studies: the GRIPS statement. Eur J Clin Invest (2011) 0.91
Basal Ki67 expression measured by digital image analysis is optimal for prognostication in oral squamous cell carcinoma. Eur J Cancer (2012) 0.90
A phase I clinical and pharmacokinetic study of Ro 31-7453 given as a 7- or 14-day oral twice daily schedule every 4 weeks in patients with solid tumors. Clin Cancer Res (2004) 0.90
Prevention by daily soluble aspirin of colorectal adenoma recurrence: 4-year results of the APACC randomised trial. Gut (2011) 0.90
Genomic changes identified by comparative genomic hybridisation in docetaxel-resistant breast cancer cell lines. Eur J Cancer (2005) 0.89
Bax expression measured by AQUAnalysis is an independent prognostic marker in oral squamous cell carcinoma. BMC Cancer (2012) 0.89
An international case-control study of adult diet and brain tumor risk: a histology-specific analysis by food group. Ann Epidemiol (2009) 0.89
Refining the management of low-grade cervical abnormalities in the UK National Health Service and defining the potential for human papillomavirus testing: a commentary on emerging evidence. J Low Genit Tract Dis (2006) 0.88
CYP3A4 promoter variant is associated with prostate cancer risk in men with benign prostate hyperplasia. Oncol Rep (2002) 0.88
Relation of childhood brain tumors to exposure of parents and children to tobacco smoke: the SEARCH international case-control study. Surveillance of Environmental Aspects Related to Cancer in Humans. Int J Cancer (2002) 0.87
Strengthening the reporting of genetic risk prediction studies: the GRIPS statement. BMJ (2011) 0.87
Folate, DNA stability and colo-rectal neoplasia. Proc Nutr Soc (2004) 0.87
Sugar and fat intake among children in Scotland: what is needed to reach the dietary targets? Public Health Nutr (2009) 0.86
Folic acid supplementation use and the MTHFR C677T polymorphism in orofacial clefts etiology: An individual participant data pooled-analysis. Birth Defects Res A Clin Mol Teratol (2013) 0.86
Expectations and values about expanded newborn screening: a public engagement study. Health Expect (2013) 0.86
Vitamin D receptor (VDR) polymorphisms and severe RSV bronchiolitis: a systematic review and meta-analysis. Pediatr Pulmonol (2013) 0.85
Vitamin D receptor, HER-2 polymorphisms and risk of prostate cancer in men with benign prostate hyperplasia. Saudi Med J (2004) 0.85
Strengthening the reporting of Genetic Risk Prediction Studies: the GRIPS statement. Genet Med (2011) 0.85