Published in Nucleic Acids Res on December 01, 2007
Modeling reveals bistability and low-pass filtering in the network module determining blood stem cell fate. PLoS Comput Biol (2010) 1.12
Non-transcriptional regulatory processes shape transcriptional network dynamics. Nat Rev Microbiol (2011) 1.04
DNA looping in prokaryotes: experimental and theoretical approaches. J Bacteriol (2013) 1.03
Accurate prediction of gene expression by integration of DNA sequence statistics with detailed modeling of transcription regulation. Biophys J (2010) 0.84
Rational design of modular circuits for gene transcription: A test of the bottom-up approach. J Biol Eng (2010) 0.84
The RpiR-like repressor IolR regulates inositol catabolism in Sinorhizobium meliloti. J Bacteriol (2011) 0.83
Theoretical and experimental dissection of DNA loop-mediated repression. Phys Rev Lett (2013) 0.82
Systems biophysics of gene expression. Biophys J (2013) 0.80
Control of gene expression by modulated self-assembly. Nucleic Acids Res (2011) 0.80
Comparison of the theoretical and real-world evolutionary potential of a genetic circuit. Phys Biol (2014) 0.78
Deterministic and stochastic population-level simulations of an artificial lac operon genetic network. BMC Bioinformatics (2011) 0.78
Supercoiling Effects on Short-Range DNA Looping in E. coli. PLoS One (2016) 0.75
Self-consistent theory of transcriptional control in complex regulatory architectures. PLoS One (2017) 0.75
A genomic code for nucleosome positioning. Nature (2006) 15.38
Looping and interaction between hypersensitive sites in the active beta-globin locus. Mol Cell (2002) 11.35
Crystal structure of the lactose operon repressor and its complexes with DNA and inducer. Science (1996) 9.34
Transcriptional regulatory elements in the human genome. Annu Rev Genomics Hum Genet (2006) 7.18
Transcription activation by catabolite activator protein (CAP). J Mol Biol (1999) 6.08
Combinatorial synthesis of genetic networks. Science (2002) 5.91
Going the distance: a current view of enhancer action. Science (1998) 5.83
The three operators of the lac operon cooperate in repression. EMBO J (1990) 5.45
DNA looping. Annu Rev Biochem (1992) 5.26
Quantitative model for gene regulation by lambda phage repressor. Proc Natl Acad Sci U S A (1982) 4.93
Detailed map of a cis-regulatory input function. Proc Natl Acad Sci U S A (2003) 4.30
Mechanisms of site-specific recombination. Annu Rev Biochem (2006) 4.29
A bottom-up approach to gene regulation. Nature (2006) 4.03
Repression of lac promoter as a function of distance, phase and quality of an auxiliary lac operator. J Mol Biol (1996) 3.08
Quality and position of the three lac operators of E. coli define efficiency of repression. EMBO J (1994) 2.90
Structural basis of transcription activation: the CAP-alpha CTD-DNA complex. Science (2002) 2.67
T-loops and the origin of telomeres. Nat Rev Mol Cell Biol (2004) 2.54
Combinatorial transcriptional control of the lactose operon of Escherichia coli. Proc Natl Acad Sci U S A (2007) 2.51
SsrA-mediated tagging and proteolysis of LacI and its role in the regulation of lac operon. EMBO J (2000) 2.08
DNA looping in gene regulation: from the assembly of macromolecular complexes to the control of transcriptional noise. Curr Opin Genet Dev (2005) 2.03
Conformational spread: the propagation of allosteric states in large multiprotein complexes. Annu Rev Biophys Biomol Struct (2004) 2.03
DNA looping between the origin of replication of Epstein-Barr virus and its enhancer site: stabilization of an origin complex with Epstein-Barr nuclear antigen 1. Proc Natl Acad Sci U S A (1991) 1.86
p53 oligomerization and DNA looping are linked with transcriptional activation. EMBO J (1994) 1.57
Co-operative interactions between the catabolite gene activator protein and the lac repressor at the lactose promoter. J Mol Biol (1990) 1.55
DNA looping: the consequences and its control. Curr Opin Struct Biol (2006) 1.51
Signaling through receptors and scaffolds: independent interactions reduce combinatorial complexity. Biophys J (2005) 1.44
Inferring the in vivo looping properties of DNA. Proc Natl Acad Sci U S A (2005) 1.21
Induction of the lac promoter in the absence of DNA loops and the stoichiometry of induction. Nucleic Acids Res (2006) 1.16
Multilevel deconstruction of the In vivo behavior of looped DNA-protein complexes. PLoS One (2007) 1.02
Stochastic dynamics of macromolecular-assembly networks. Mol Syst Biol (2006) 1.00
Effect of DNA looping on the induction kinetics of the lac operon. J Theor Biol (2007) 0.97
DNA-looping by RXR tetramers permits transcriptional regulation "at a distance". J Mol Biol (2004) 0.94
Escherichia coli lac repressor-lac operator interaction and the influence of allosteric effectors. J Mol Biol (1997) 0.84
Thermodynamics, protein modification, and molecular dynamics in characterizing lactose repressor protein: strategies for complex analyses of protein structure-function. Methods Enzymol (2004) 0.84
Modularizing gene regulation. Mol Syst Biol (2006) 0.79
From molecular noise to behavioural variability in a single bacterium. Nature (2004) 4.28
Synthetic cooperation in engineered yeast populations. Proc Natl Acad Sci U S A (2007) 2.62
DNA looping: the consequences and its control. Curr Opin Struct Biol (2006) 1.51
Inferring the in vivo looping properties of DNA. Proc Natl Acad Sci U S A (2005) 1.21
Multilevel deconstruction of the In vivo behavior of looped DNA-protein complexes. PLoS One (2007) 1.02
Stochastic dynamics of macromolecular-assembly networks. Mol Syst Biol (2006) 1.00
Optimal resting-growth strategies of microbial populations in fluctuating environments. PLoS One (2011) 0.80
Modularizing gene regulation. Mol Syst Biol (2006) 0.79
Reliable prediction of complex phenotypes from a modular design in free energy space: an extensive exploration of the lac operon. ACS Synth Biol (2013) 0.77