Published in Annu Rev Biochem on January 01, 2006
piggyBac can bypass DNA synthesis during cut and paste transposition. EMBO J (2008) 2.27
Rewritable digital data storage in live cells via engineered control of recombination directionality. Proc Natl Acad Sci U S A (2012) 2.03
Synthesis of programmable integrases. Proc Natl Acad Sci U S A (2009) 1.94
Architecture of a serine recombinase-DNA regulatory complex. Mol Cell (2008) 1.84
Strategies to achieve conditional gene mutation in mice. Cold Spring Harb Protoc (2014) 1.54
Single-molecule analysis reveals the molecular bearing mechanism of DNA strand exchange by a serine recombinase. Proc Natl Acad Sci U S A (2011) 1.52
Mechanism of IS200/IS605 family DNA transposases: activation and transposon-directed target site selection. Cell (2008) 1.51
Helicobacter Pylori's plasticity zones are novel transposable elements. PLoS One (2009) 1.48
Epigenetic Switch Driven by DNA Inversions Dictates Phase Variation in Streptococcus pneumoniae. PLoS Pathog (2016) 1.40
Structural basis for catalytic activation of a serine recombinase. Structure (2011) 1.39
Chimeric TALE recombinases with programmable DNA sequence specificity. Nucleic Acids Res (2012) 1.38
Integrating prokaryotes and eukaryotes: DNA transposases in light of structure. Crit Rev Biochem Mol Biol (2010) 1.35
Targeting individual subunits of the FokI restriction endonuclease to specific DNA strands. Nucleic Acids Res (2009) 1.32
Bacterial genome instability. Microbiol Mol Biol Rev (2014) 1.31
Structure-guided reprogramming of serine recombinase DNA sequence specificity. Proc Natl Acad Sci U S A (2010) 1.31
Breaking and joining single-stranded DNA: the HUH endonuclease superfamily. Nat Rev Microbiol (2013) 1.28
A motif in the C-terminal domain of phiC31 integrase controls the directionality of recombination. Nucleic Acids Res (2008) 1.25
Casposons: a new superfamily of self-synthesizing DNA transposons at the origin of prokaryotic CRISPR-Cas immunity. BMC Biol (2014) 1.25
Recombinase technology: applications and possibilities. Plant Cell Rep (2010) 1.25
The complete genomes of Staphylococcus aureus bacteriophages 80 and 80α--implications for the specificity of SaPI mobilization. Virology (2010) 1.23
Mutational derivatives of PhiC31 integrase with increased efficiency and specificity. Mol Ther (2008) 1.23
Multiple new site-specific recombinases for use in manipulating animal genomes. Proc Natl Acad Sci U S A (2011) 1.23
Directed evolution of recombinase specificity by split gene reassembly. Nucleic Acids Res (2010) 1.19
Marker removal in staphylococci via Cre recombinase and different lox sites. Appl Environ Microbiol (2007) 1.18
Structural features of single-stranded integron cassette attC sites and their role in strand selection. PLoS Genet (2009) 1.15
Rates of gyrase supercoiling and transcription elongation control supercoil density in a bacterial chromosome. PLoS Genet (2012) 1.14
Two-step site selection for serine-integrase-mediated excision: DNA-directed integrase conformation and central dinucleotide proofreading. Proc Natl Acad Sci U S A (2008) 1.12
Gene therapy vectors: the prospects and potentials of the cut-and-paste transposons. Genetica (2009) 1.10
Type III restriction enzymes cleave DNA by long-range interaction between sites in both head-to-head and tail-to-tail inverted repeat. Proc Natl Acad Sci U S A (2010) 1.08
Plasmid addiction systems: perspectives and applications in biotechnology. Microb Biotechnol (2010) 1.07
Identification of key structural determinants of the IntI1 integron integrase that influence attC x attI1 recombination efficiency. Nucleic Acids Res (2007) 1.04
Insertion of horizontally transferred genes within conserved syntenic regions of yeast genomes. PLoS One (2009) 1.04
Remote control of DNA-acting enzymes by varying the Brownian dynamics of a distant DNA end. Proc Natl Acad Sci U S A (2012) 1.04
A comprehensive approach to zinc-finger recombinase customization enables genomic targeting in human cells. Nucleic Acids Res (2013) 1.04
Two novel families of plasmids from hyperthermophilic archaea encoding new families of replication proteins. Nucleic Acids Res (2010) 1.04
A biotin interference assay highlights two different asymmetric interaction profiles for lambda integrase arm-type binding sites in integrative versus excisive recombination. J Biol Chem (2008) 1.03
Chloroplast DNA sequence of the green alga Oedogonium cardiacum (Chlorophyceae): unique genome architecture, derived characters shared with the Chaetophorales and novel genes acquired through horizontal transfer. BMC Genomics (2008) 1.02
Complete WO phage sequences reveal their dynamic evolutionary trajectories and putative functional elements required for integration into the Wolbachia genome. Appl Environ Microbiol (2009) 1.01
Moving DNA around: DNA transposition and retroviral integration. Curr Opin Struct Biol (2011) 1.00
Synapsis and catalysis by activated Tn3 resolvase mutants. Nucleic Acids Res (2008) 1.00
Capturing reaction paths and intermediates in Cre-loxP recombination using single-molecule fluorescence. Proc Natl Acad Sci U S A (2012) 1.00
A novel streptococcal integrative conjugative element involved in iron acquisition. Mol Microbiol (2008) 0.99
Origins of the Xylella fastidiosa prophage-like regions and their impact in genome differentiation. PLoS One (2008) 0.99
Regulatory mutations in Sin recombinase support a structure-based model of the synaptosome. Mol Microbiol (2009) 0.99
Insights from the structure of a smallpox virus topoisomerase-DNA transition state mimic. Structure (2010) 0.98
Evolution of cagA oncogene of Helicobacter pylori through recombination. PLoS One (2011) 0.98
Requirements for catalysis in the Cre recombinase active site. Nucleic Acids Res (2010) 0.98
New applications for phage integrases. J Mol Biol (2014) 0.98
Are two better than one? Analysis of an FtsK/Xer recombination system that uses a single recombinase. Nucleic Acids Res (2010) 0.97
Attachment site recognition and regulation of directionality by the serine integrases. Nucleic Acids Res (2013) 0.97
DNA-catalyzed covalent modification of amino acid side chains in tethered and free peptide substrates. Biochemistry (2011) 0.97
DNA binding and synapsis by the large C-terminal domain of phiC31 integrase. Nucleic Acids Res (2009) 0.97
DNA-catalyzed serine side chain reactivity and selectivity. Chem Commun (Camb) (2010) 0.96
Less is more: strategies to remove marker genes from transgenic plants. BMC Biotechnol (2013) 0.96
Highly efficient in vitro site-specific recombination system based on streptomyces phage phiBT1 integrase. J Bacteriol (2008) 0.96
A transposase-independent mechanism gives rise to precise excision of IS256 from insertion sites in Staphylococcus epidermidis. J Bacteriol (2007) 0.95
Programming a Human Commensal Bacterium, Bacteroides thetaiotaomicron, to Sense and Respond to Stimuli in the Murine Gut Microbiota. Cell Syst (2015) 0.95
Tandem assembly of the epothilone biosynthetic gene cluster by in vitro site-specific recombination. Sci Rep (2011) 0.95
Roles of two large serine recombinases in mobilizing the methicillin-resistance cassette SCCmec. Mol Microbiol (2013) 0.95
Identification of a potential general acid/base in the reversible phosphoryl transfer reactions catalyzed by tyrosine recombinases: Flp H305. Chem Biol (2007) 0.95
Zinc finger recombinases with adaptable DNA sequence specificity. PLoS One (2011) 0.95
Mechanical constraints on Hin subunit rotation imposed by the Fis/enhancer system and DNA supercoiling during site-specific recombination. Mol Cell (2009) 0.95
Crystal structure of an intermediate of rotating dimers within the synaptic tetramer of the G-segment invertase. Nucleic Acids Res (2012) 0.94
Ab initio thermodynamic modeling of distal multisite transcription regulation. Nucleic Acids Res (2007) 0.93
Accuracy and efficiency define Bxb1 integrase as the best of fifteen candidate serine recombinases for the integration of DNA into the human genome. BMC Biotechnol (2013) 0.93
Integrative and Conjugative Elements (ICEs): What They Do and How They Work. Annu Rev Genet (2015) 0.93
Expanding the scope of site-specific recombinases for genetic and metabolic engineering. Biotechnol Bioeng (2013) 0.92
DICE, an efficient system for iterative genomic editing in human pluripotent stem cells. Nucleic Acids Res (2013) 0.92
The Hin recombinase assembles a tetrameric protein swivel that exchanges DNA strands. Nucleic Acids Res (2009) 0.91
Gated rotation mechanism of site-specific recombination by ϕC31 integrase. Proc Natl Acad Sci U S A (2012) 0.91
Dynamics and consequences of DNA looping by the FokI restriction endonuclease. Nucleic Acids Res (2008) 0.90
New transposon Tn6133 in methicillin-resistant Staphylococcus aureus ST398 contains vga(E), a novel streptogramin A, pleuromutilin, and lincosamide resistance gene. Antimicrob Agents Chemother (2011) 0.90
In vivo evaluation of PhiC31 recombinase activity using a self-excision cassette. Nucleic Acids Res (2008) 0.90
Chromosomal DNA deletion confers phage resistance to Pseudomonas aeruginosa. Sci Rep (2014) 0.89
The catalytic residues of Tn3 resolvase. Nucleic Acids Res (2009) 0.89
Conformational transitions during FtsK translocase activation of individual XerCD-dif recombination complexes. Proc Natl Acad Sci U S A (2013) 0.88
Light-inducible genetic engineering and control of non-homologous end-joining in industrial eukaryotic microorganisms: LML 3.0 and OFN 1.0. Sci Rep (2016) 0.87
Dynamics of synaptic SfiI-DNA complex: single-molecule fluorescence analysis. Biophys J (2007) 0.87
Genome engineering and direct cloning of antibiotic gene clusters via phage ϕBT1 integrase-mediated site-specific recombination in Streptomyces. Sci Rep (2015) 0.87
Sin resolvase catalytic activity and oligomerization state are tightly coupled. J Mol Biol (2010) 0.87
DNA looping by FokI: the impact of synapse geometry on loop topology at varied site orientations. Nucleic Acids Res (2012) 0.86
The Bxb1 gp47 recombination directionality factor is required not only for prophage excision, but also for phage DNA replication. Gene (2011) 0.86
A genomic islet mediates flagellar phase variation in Escherichia coli strains carrying the flagellin-specifying locus flk. J Bacteriol (2008) 0.86
Site-specific recombination systems in filamentous phages. Mol Genet Genomics (2012) 0.86
Zinc is essential for high-affinity DNA binding and recombinase activity of ΦC31 integrase. Nucleic Acids Res (2011) 0.86
Replicative resolution of integron cassette insertion. Nucleic Acids Res (2012) 0.86
Attachment site selection and identity in Bxb1 serine integrase-mediated site-specific recombination. PLoS Genet (2013) 0.85
DNA cleavage site selection by Type III restriction enzymes provides evidence for head-on protein collisions following 1D bidirectional motion. Nucleic Acids Res (2011) 0.84
Multiple interfaces between a serine recombinase and an enhancer control site-specific DNA inversion. Elife (2013) 0.84
A generalizable DNA-catalyzed approach to peptide-nucleic acid conjugation. Chembiochem (2014) 0.84
Multicellular computing using conjugation for wiring. PLoS One (2013) 0.84
Zinc-finger recombinase activities in vitro. Nucleic Acids Res (2011) 0.84
The site-specific integration reaction of Listeria phage A118 integrase, a serine recombinase. Mob DNA (2013) 0.84
Binary recombinase systems for high-resolution conditional mutagenesis. Nucleic Acids Res (2014) 0.83
Preventing broken Borrelia telomeres: ResT couples dual hairpin telomere formation with product release. J Biol Chem (2010) 0.83
Control of directionality in Streptomyces phage φBT1 integrase-mediated site-specific recombination. PLoS One (2013) 0.83
Protein-induced local DNA bends regulate global topology of recombination products. J Mol Biol (2007) 0.83
Towards a more accurate annotation of tyrosine-based site-specific recombinases in bacterial genomes. Mob DNA (2012) 0.83
Mechanism and specificity of DNA strand exchange catalyzed by vaccinia DNA topoisomerase type I. Biochemistry (2010) 0.82
Site-specific DNA Inversion by Serine Recombinases. Microbiol Spectr (2015) 0.82
Bacteriophage adhering to mucus provide a non-host-derived immunity. Proc Natl Acad Sci U S A (2013) 3.86
Crystal structure of a Rad51 filament. Nat Struct Mol Biol (2004) 2.83
IHF and HU: flexible architects of bent DNA. Curr Opin Struct Biol (2004) 2.80
Crystal structures of DNA/RNA repair enzymes AlkB and ABH2 bound to dsDNA. Nature (2008) 2.30
Flexible DNA bending in HU-DNA cocrystal structures. EMBO J (2003) 2.15
Architecture of a serine recombinase-DNA regulatory complex. Mol Cell (2008) 1.84
An oxidation-sensing mechanism is used by the global regulator MgrA in Staphylococcus aureus. Nat Chem Biol (2006) 1.83
Biogeochemical forces shape the composition and physiology of polymicrobial communities in the cystic fibrosis lung. MBio (2014) 1.74
Structural basis for catalytic activation of a serine recombinase. Structure (2011) 1.39
Integration host factor: putting a twist on protein-DNA recognition. J Mol Biol (2003) 1.28
The structure of the human AGT protein bound to DNA and its implications for damage detection. J Mol Biol (2005) 1.26
The μ transpososome structure sheds light on DDE recombinase evolution. Nature (2012) 1.22
Crystal structures of the reduced, sulfenic acid, and mixed disulfide forms of SarZ, a redox active global regulator in Staphylococcus aureus. J Biol Chem (2009) 1.21
New insight into site-specific recombination from Flp recombinase-DNA structures. Annu Rev Biophys Biomol Struct (2003) 1.20
Automated real-space refinement of protein structures using a realistic backbone move set. Biophys J (2011) 1.16
Amino acid residues in Rag1 crucial for DNA hairpin formation. Nat Struct Mol Biol (2006) 1.16
Structure of the LexA-DNA complex and implications for SOS box measurement. Nature (2010) 1.16
Shaping the Borrelia burgdorferi genome: crystal structure and binding properties of the DNA-bending protein Hbb. Mol Microbiol (2007) 1.12
Structural plasticity of the Flp-Holliday junction complex. J Mol Biol (2003) 1.10
Structure-based analysis of HU-DNA binding. J Mol Biol (2006) 1.07
The role of the conserved Trp330 in Flp-mediated recombination. Functional and structural analysis. J Biol Chem (2003) 1.06
Moving DNA around: DNA transposition and retroviral integration. Curr Opin Struct Biol (2011) 1.00
Regulatory mutations in Sin recombinase support a structure-based model of the synaptosome. Mol Microbiol (2009) 0.99
Roles of two large serine recombinases in mobilizing the methicillin-resistance cassette SCCmec. Mol Microbiol (2013) 0.95
Identification of a potential general acid/base in the reversible phosphoryl transfer reactions catalyzed by tyrosine recombinases: Flp H305. Chem Biol (2007) 0.95
Regulation of Rad51 function by phosphorylation. EMBO Rep (2011) 0.91
Protein binding has a large effect on radical mediated DNA damage. J Am Chem Soc (2008) 0.88
Sin resolvase catalytic activity and oligomerization state are tightly coupled. J Mol Biol (2010) 0.87
Inter-subunit interactions that coordinate Rad51's activities. Nucleic Acids Res (2008) 0.85
Control of transposase activity within a transpososome by the configuration of the flanking DNA segment of the transposon. Proc Natl Acad Sci U S A (2007) 0.85
Binding then bending: a mechanism for wrapping DNA. Proc Natl Acad Sci U S A (2006) 0.84
Mapping the transition state for DNA bending by IHF. J Mol Biol (2012) 0.81
Binding and catalytic contributions to site recognition by flp recombinase. J Biol Chem (2008) 0.81
Resolving integral questions in site-specific recombination. Nat Struct Mol Biol (2005) 0.80
Arginine as a general acid catalyst in serine recombinase-mediated DNA cleavage. J Biol Chem (2013) 0.80
Serine Resolvases. Microbiol Spectr (2015) 0.79
Global analysis of ion dependence unveils hidden steps in DNA binding and bending by integration host factor. J Chem Phys (2013) 0.76
Guest editorial: Mobile genetic elements and horizontal gene transfer in prokaryotes. Curr Opin Microbiol (2017) 0.75
Meeting report for mobile DNA 2010. Mob DNA (2010) 0.75