Mechanisms for enveloped virus budding: can some viruses do without an ESCRT?

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Published in Virology on December 11, 2007

Authors

Benjamin J Chen1, Robert A Lamb

Author Affiliations

1: Department of Biochemistry, Molecular Biology and Cell Biology, Northwestern University, Evanston, Illinois 60208-3500, USA.

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Structure of the Newcastle disease virus F protein in the post-fusion conformation. Virology (2010) 1.29

Conserved glycine residues in the fusion peptide of the paramyxovirus fusion protein regulate activation of the native state. J Virol (2004) 1.24

Identification of the pore-lining residues of the BM2 ion channel protein of influenza B virus. J Biol Chem (2008) 1.20

Functional analysis of the transmembrane domain in paramyxovirus F protein-mediated membrane fusion. J Mol Biol (2008) 1.16

Influenza virus proton channels. Photochem Photobiol Sci (2006) 1.16

Recombinant parainfluenza virus 5 (PIV5) expressing the influenza A virus hemagglutinin provides immunity in mice to influenza A virus challenge. Virology (2007) 1.16

Expression and initial structural insights from solid-state NMR of the M2 proton channel from influenza A virus. Biochemistry (2002) 1.16

Conserved cysteine-rich domain of paramyxovirus simian virus 5 V protein plays an important role in blocking apoptosis. J Virol (2004) 1.15

Characterization of EBV gB indicates properties of both class I and class II viral fusion proteins. Virology (2007) 1.13

Capture and imaging of a prehairpin fusion intermediate of the paramyxovirus PIV5. Proc Natl Acad Sci U S A (2011) 1.12

Structure of the human metapneumovirus fusion protein with neutralizing antibody identifies a pneumovirus antigenic site. Nat Struct Mol Biol (2012) 1.11

Structure of the parainfluenza virus 5 (PIV5) hemagglutinin-neuraminidase (HN) ectodomain. PLoS Pathog (2013) 1.10

Influenza virus is not restricted by tetherin whereas influenza VLP production is restricted by tetherin. Virology (2011) 1.08

Mutations in the parainfluenza virus 5 fusion protein reveal domains important for fusion triggering and metastability. J Virol (2013) 1.08

Autophagy, apoptosis, and the influenza virus M2 protein. Cell Host Microbe (2009) 1.08

The oligomeric state of the active BM2 ion channel protein of influenza B virus. J Biol Chem (2007) 1.05

Fusion activation through attachment protein stalk domains indicates a conserved core mechanism of paramyxovirus entry into cells. J Virol (2014) 1.04

Discovery of novel dual inhibitors of the wild-type and the most prevalent drug-resistant mutant, S31N, of the M2 proton channel from influenza A virus. J Med Chem (2013) 1.03

Filamentous influenza virus enters cells via macropinocytosis. J Virol (2012) 1.02

A pH-dependent conformational ensemble mediates proton transport through the influenza A/M2 protein. Biochemistry (2010) 1.01

Comparison of differing cytopathic effects in human airway epithelium of parainfluenza virus 5 (W3A), parainfluenza virus type 3, and respiratory syncytial virus. Virology (2011) 1.01

Exploring organosilane amines as potent inhibitors and structural probes of influenza a virus M2 proton channel. J Am Chem Soc (2011) 1.01

Exploring the size limit of templates for inhibitors of the M2 ion channel of influenza A virus. J Med Chem (2011) 1.00

Influenza virus budding does not require a functional AAA+ ATPase, VPS4. Virus Res (2010) 0.97

Paramyxovirus fusion: real-time measurement of parainfluenza virus 5 virus-cell fusion. Virology (2006) 0.95

The amphipathic helix of influenza A virus M2 protein is required for filamentous bud formation and scission of filamentous and spherical particles. J Virol (2013) 0.95

The paramyxovirus fusion protein C-terminal region: mutagenesis indicates an indivisible protein unit. J Virol (2011) 0.95

The influenza A virus spliced messenger RNA M mRNA3 is not required for viral replication in tissue culture. J Gen Virol (2008) 0.94

Analysis of the pH requirement for membrane fusion of different isolates of the paramyxovirus parainfluenza virus 5. J Virol (2006) 0.93

Exploring the Requirements for the Hydrophobic Scaffold and Polar Amine in inhibitors of M2 from Influenza A Virus. ACS Med Chem Lett (2011) 0.92

Viral membrane scission. Annu Rev Cell Dev Biol (2013) 0.92

Monitoring single-cell infectivity from virus-particle nanoarrays fabricated by parallel dip-pen nanolithography. Small (2007) 0.92

A role for caveolin 1 in assembly and budding of the paramyxovirus parainfluenza virus 5. J Virol (2010) 0.90

A fluorescence polarization assay using an engineered human respiratory syncytial virus F protein as a direct screening platform. Anal Biochem (2010) 0.85

Asp44 stabilizes the Trp41 gate of the M2 proton channel of influenza A virus. Structure (2013) 0.85

3-Azatetracyclo[5.2.1.1(5,8).0(1,5)]undecane derivatives: from wild-type inhibitors of the M2 ion channel of influenza A virus to derivatives with potent activity against the V27A mutant. J Med Chem (2013) 0.85

Flipping in the pore: discovery of dual inhibitors that bind in different orientations to the wild-type versus the amantadine-resistant S31N mutant of the influenza A virus M2 proton channel. J Am Chem Soc (2014) 0.85

Functional antibody arrays through metal ion-affinity templates. Chembiochem (2006) 0.83

Analysis of parainfluenza virus-5 hemagglutinin-neuraminidase protein mutants that are blocked in internalization and degradation. Virology (2010) 0.83

Reversible inhibition of fusion activity of a paramyxovirus fusion protein by an engineered disulfide bond in the membrane-proximal external region. J Virol (2012) 0.82

Easily accessible polycyclic amines that inhibit the wild-type and amantadine-resistant mutants of the M2 channel of influenza A virus. J Med Chem (2014) 0.79

Inhibitors of the influenza A virus M2 proton channel discovered using a high-throughput yeast growth restoration assay. PLoS One (2013) 0.78

Swine-origin influenza virus and the 2009 pandemic. Am J Respir Crit Care Med (2010) 0.78

Deadly H7N9 influenza virus: a pandemic in the making or a warning lesson? Am J Respir Crit Care Med (2013) 0.77

Viral ion channels as models for ion transport and targets for antiviral drug action. FEBS Lett (2004) 0.77

Extinct 1918 virus comes alive. Nat Med (2005) 0.76

Enhanced performance photon-counting time-of-flight sensor. Opt Express (2007) 0.75

Single-photon three-dimensional imaging at up to 10 kilometers range. Opt Express (2017) 0.75

Towards industrial ultrafast laser microwelding: SiO2 and BK7 to aluminum alloy. Appl Opt (2017) 0.75