Published in Thromb Haemost on December 01, 2007
Evidence for activation of tissue factor by an allosteric disulfide bond. Biochemistry (2006) 1.99
Platelet physiology and thrombosis. Thromb Res (2004) 1.90
High shear-dependent loss of membrane integrity and defective platelet adhesion following disruption of the GPIbα-filamin interaction. Blood (2010) 1.75
Bcl-xL-inhibitory BH3 mimetics can induce a transient thrombocytopathy that undermines the hemostatic function of platelets. Blood (2011) 1.56
Glycoprotein Ibalpha inhibitor complex structure reveals a combined steric and allosteric mechanism of von Willebrand factor antagonism. Blood (2009) 1.51
The dimeric versus monomeric status of 14-3-3zeta is controlled by phosphorylation of Ser58 at the dimer interface. J Biol Chem (2003) 1.49
Sphingosine kinase-1 enhances endothelial cell survival through a PECAM-1-dependent activation of PI-3K/Akt and regulation of Bcl-2 family members. Blood (2005) 1.47
TAC-1, a regulator of microtubule length in the C. elegans embryo. Curr Biol (2003) 1.46
Coagulation-induced shedding of platelet glycoprotein VI mediated by factor Xa. Blood (2011) 1.44
Association of Fyn and Lyn with the proline-rich domain of glycoprotein VI regulates intracellular signaling. J Biol Chem (2002) 1.39
P-selectin anchors newly released ultralarge von Willebrand factor multimers to the endothelial cell surface. Blood (2003) 1.34
GPVI levels in platelets: relationship to platelet function at high shear. Blood (2003) 1.23
Bruton tyrosine kinase is essential for botrocetin/VWF-induced signaling and GPIb-dependent thrombus formation in vivo. Blood (2006) 1.22
Botrocetin/VWF-induced signaling through GPIb-IX-V produces TxA2 in an alphaIIbbeta3- and aggregation-independent manner. Blood (2005) 1.21
A critical role for 14-3-3zeta protein in regulating the VWF binding function of platelet glycoprotein Ib-IX and its therapeutic implications. Blood (2005) 1.20
Laminin stimulates spreading of platelets through integrin alpha6beta1-dependent activation of GPVI. Blood (2005) 1.19
Analysis of the interaction of platelet collagen receptor glycoprotein VI (GPVI) with collagen. A dimeric form of GPVI, but not the monomeric form, shows affinity to fibrous collagen. J Biol Chem (2002) 1.13
Transforming growth factor beta suppresses human telomerase reverse transcriptase (hTERT) by Smad3 interactions with c-Myc and the hTERT gene. J Biol Chem (2006) 1.12
Src family tyrosine kinase Lyn mediates VWF/GPIb-IX-induced platelet activation via the cGMP signaling pathway. Blood (2008) 1.11
Interaction between von Willebrand factor and glycoprotein Ib activates Src kinase in human platelets: role of phosphoinositide 3-kinase. Blood (2002) 1.09
Regulation of glycoprotein Ib-IX-von Willebrand factor interaction by cAMP-dependent protein kinase-mediated phosphorylation at Ser 166 of glycoprotein Ib(beta). J Biol Chem (2002) 1.09
Anti-beta2-glycoprotein I antibodies in complex with beta2-glycoprotein I can activate platelets in a dysregulated manner via glycoprotein Ib-IX-V. Arthritis Rheum (2006) 1.09
Functional phenotype of phosphoinositide 3-kinase p85alpha-null platelets characterized by an impaired response to GP VI stimulation. Blood (2003) 1.07
Dual ITAM-mediated proteolytic pathways for irreversible inactivation of platelet receptors: de-ITAM-izing FcgammaRIIa. Blood (2007) 1.06
Regulation of platelet membrane levels of glycoprotein VI by a platelet-derived metalloproteinase. Blood (2004) 1.04
Leucine-rich repeats 2-4 (Leu60-Glu128) of platelet glycoprotein Ibalpha regulate shear-dependent cell adhesion to von Willebrand factor. J Biol Chem (2006) 1.03
New insights into the haemostatic function of platelets. Br J Haematol (2009) 1.01
Bernard-Soulier syndrome. Haematologica (2011) 1.00
Platelet adhesion: a game of catch and release. J Clin Invest (2008) 1.00
Platelet glycoprotein VI-related clinical defects. Br J Haematol (2007) 1.00
Identification of a novel 14-3-3zeta binding site within the cytoplasmic tail of platelet glycoprotein Ibalpha. Blood (2004) 0.99
Glycoprotein VI is associated with GPIb-IX-V on the membrane of resting and activated platelets. Thromb Haemost (2005) 0.98
Relative antithrombotic effect of soluble GPVI dimer compared with anti-GPVI antibodies in mice. Blood (2004) 0.97
Glycoproteins VI and Ib-IX-V stimulate tyrosine phosphorylation of tyrosine kinase Syk and phospholipase Cgamma2 at distinct sites. Biochem J (2004) 0.96
The LFA-1-associated molecule PTA-1 (CD226) on T cells forms a dynamic molecular complex with protein 4.1G and human discs large. J Biol Chem (2004) 0.96
Angiotensin II-inducible platelet-derived growth factor-D transcription requires specific Ser/Thr residues in the second zinc finger region of Sp1. Circ Res (2008) 0.95
Delineation of the region in the glycoprotein VI tail required for association with the Fc receptor gamma-chain. J Biol Chem (2003) 0.93
Platelet receptor proteolysis: a mechanism for downregulating platelet reactivity. Arterioscler Thromb Vasc Biol (2007) 0.92
The role of Rac1 in glycoprotein Ib-IX-mediated signal transduction and integrin activation. Arterioscler Thromb Vasc Biol (2012) 0.92
Glycoprotein IIb-IIIa-dependent aggregation by glycoprotein Ibalpha is reinforced by a Src family kinase inhibitor (PP1)-sensitive signalling pathway. Biochem J (2002) 0.92
Constitutive dimerization of glycoprotein VI (GPVI) in resting platelets is essential for binding to collagen and activation in flowing blood. J Biol Chem (2012) 0.92
Antihemostatic activity of human granzyme B mediated by cleavage of von Willebrand factor. J Biol Chem (2008) 0.92
Neutrophil extracellular traps (NETs) and the role of platelets in infection. Thromb Haemost (2014) 0.91
Proteolysis of platelet receptors in humans and other species. Biol Chem (2010) 0.91
Neutrophil extracellular traps (NETs) and infection-related vascular dysfunction. Blood Rev (2012) 0.89
The Fc receptor gamma-chain is necessary and sufficient to initiate signalling through glycoprotein VI in transfected cells by the snake C-type lectin, convulxin. Eur J Biochem (2002) 0.89
Platelet receptor redox regulation. Platelets (2008) 0.88
The cryptome: a subset of the proteome, comprising cryptic peptides with distinct bioactivities. Drug Discov Today (2006) 0.88
LIM kinase-1 selectively promotes glycoprotein Ib-IX-mediated TXA2 synthesis, platelet activation, and thrombosis. Blood (2013) 0.88
Interaction of calmodulin with the cytoplasmic domain of platelet glycoprotein VI. Blood (2002) 0.87
Adhesion maturation of neutrophils on nanoscopically presented platelet glycoprotein Ibα. ACS Nano (2013) 0.87
Pathologic shear triggers shedding of vascular receptors: a novel mechanism for down-regulation of platelet glycoprotein VI in stenosed coronary vessels. Blood (2012) 0.87
Platelet interactions in thrombosis. IUBMB Life (2004) 0.86
SHIP-2 forms a tetrameric complex with filamin, actin, and GPIb-IX-V: localization of SHIP-2 to the activated platelet actin cytoskeleton. Blood (2003) 0.86
Transmembrane and trans-subunit regulation of ectodomain shedding of platelet glycoprotein Ibalpha. J Biol Chem (2010) 0.86
Soluble glycoprotein VI is raised in the plasma of patients with acute ischemic stroke. Stroke (2010) 0.85
Collagen-type specificity of glycoprotein VI as a determinant of platelet adhesion. Platelets (2008) 0.84
Ligand binding rapidly induces disulfide-dependent dimerization of glycoprotein VI on the platelet plasma membrane. J Biol Chem (2007) 0.84
Binding of von Willebrand factor to the small proteoglycan decorin. FEBS Lett (2004) 0.84
Role of calmodulin in platelet receptor function. Curr Med Chem Cardiovasc Hematol Agents (2005) 0.84
Structure and function of platelet receptors initiating blood clotting. Adv Exp Med Biol (2014) 0.83
Snake venom probes of platelet adhesion receptors and their ligands. Toxicon (2005) 0.83
Primary platelet adhesion receptors. IUBMB Life (2005) 0.83
Anti-glycoprotein VI monoclonal antibodies directly aggregate platelets independently of FcgammaRIIa and induce GPVI ectodomain shedding. Platelets (2009) 0.83