Published in Cell Microbiol on December 09, 2007
Genome-wide gene expression profiling analysis of Leishmania major and Leishmania infantum developmental stages reveals substantial differences between the two species. BMC Genomics (2008) 1.47
Aberrant host defense against Leishmania major in the absence of SLPI. J Leukoc Biol (2014) 1.41
Metabolomics to unveil and understand phenotypic diversity between pathogen populations. PLoS Negl Trop Dis (2010) 1.21
MAP kinase phosphatase-2 plays a critical role in response to infection by Leishmania mexicana. PLoS Pathog (2010) 1.09
The early interaction of Leishmania with macrophages and dendritic cells and its influence on the host immune response. Front Cell Infect Microbiol (2012) 1.08
The genome sequence of Leishmania (Leishmania) amazonensis: functional annotation and extended analysis of gene models. DNA Res (2013) 1.06
Organization and evolution of two SIDER retroposon subfamilies and their impact on the Leishmania genome. BMC Genomics (2009) 1.04
Expansion of the target of rapamycin (TOR) kinase family and function in Leishmania shows that TOR3 is required for acidocalcisome biogenesis and animal infectivity. Proc Natl Acad Sci U S A (2010) 1.03
Fine mapping of Leishmania major susceptibility Locus lmr2 and evidence of a role for Fli1 in disease and wound healing. Infect Immun (2010) 1.00
Degradation of host sphingomyelin is essential for Leishmania virulence. PLoS Pathog (2009) 1.00
Nutrient transport and pathogenesis in selected parasitic protozoa. Eukaryot Cell (2011) 0.98
Evidence that intracellular stages of Leishmania major utilize amino sugars as a major carbon source. PLoS Pathog (2010) 0.97
Characterization of a Leishmania stage-specific mitochondrial membrane protein that enhances the activity of cytochrome c oxidase and its role in virulence. Mol Microbiol (2010) 0.96
Enolase: a key player in the metabolism and a probable virulence factor of trypanosomatid parasites-perspectives for its use as a therapeutic target. Enzyme Res (2011) 0.95
Induction of a stringent metabolic response in intracellular stages of Leishmania mexicana leads to increased dependence on mitochondrial metabolism. PLoS Pathog (2014) 0.95
Intracellular pathogen Leishmania donovani activates hypoxia inducible factor-1 by dual mechanism for survival advantage within macrophage. PLoS One (2012) 0.92
Regulation and biological function of a flagellar glucose transporter in Leishmania mexicana: a potential glucose sensor. FASEB J (2014) 0.91
Trypanosoma cruzi: role of δ-amastin on extracellular amastigote cell invasion and differentiation. PLoS One (2012) 0.89
Histoplasma capsulatum depends on de novo vitamin biosynthesis for intraphagosomal proliferation. Infect Immun (2013) 0.88
Over-expression of mitogen-activated protein kinase phosphatase-2 enhances adhesion molecule expression and protects against apoptosis in human endothelial cells. Br J Pharmacol (2010) 0.88
Determination of antiprotozoal drug mechanisms by metabolomics approaches. Parasitology (2013) 0.86
Leishmania infantum amastigotes enhance HIV-1 production in cocultures of human dendritic cells and CD4 T cells by inducing secretion of IL-6 and TNF-alpha. PLoS Negl Trop Dis (2009) 0.86
Disruption of the lipid-transporting LdMT-LdRos3 complex in Leishmania donovani affects membrane lipid asymmetry but not host cell invasion. PLoS One (2010) 0.85
Amplification of an alternate transporter gene suppresses the avirulent phenotype of glucose transporter null mutants in Leishmania mexicana. Mol Microbiol (2008) 0.85
Analysis of the secretomes of Paracoccidioides mycelia and yeast cells. PLoS One (2012) 0.85
Berberine chloride mediates its anti-leishmanial activity via differential regulation of the mitogen activated protein kinase pathway in macrophages. PLoS One (2011) 0.85
Deletion of UDP-glucose pyrophosphorylase reveals a UDP-glucose independent UDP-galactose salvage pathway in Leishmania major. Glycobiology (2010) 0.84
Stage-specific pathways of Leishmania infantum chagasi entry and phagosome maturation in macrophages. PLoS One (2011) 0.83
Heme uptake mediated by LHR1 is essential for Leishmania amazonensis virulence. Infect Immun (2013) 0.83
Metabolic variation during development in culture of Leishmania donovani promastigotes. PLoS Negl Trop Dis (2011) 0.83
Leishmania infantum amastigotes trigger a subpopulation of human B cells with an immunoregulatory phenotype. PLoS Negl Trop Dis (2015) 0.81
Metabolic characterization of Leishmania major infection in activated and nonactivated macrophages. J Proteome Res (2012) 0.81
Axenic Leishmania amazonensis promastigotes sense both the external and internal arginine pool distinctly regulating the two transporter-coding genes. PLoS One (2011) 0.81
Global changes in gene expression by the opportunistic pathogen Burkholderia cenocepacia in response to internalization by murine macrophages. BMC Genomics (2012) 0.80
Histoplasma capsulatum surmounts obstacles to intracellular pathogenesis. FEBS J (2015) 0.79
Lysosomal degradation of Leishmania hexose and inositol transporters is regulated in a stage-, nutrient- and ubiquitin-dependent manner. Int J Parasitol (2011) 0.79
Recent developments in the interactions between caveolin and pathogens. Adv Exp Med Biol (2012) 0.78
Leishmania eukaryotic initiation factor (LeIF) inhibits parasite growth in murine macrophages. PLoS One (2014) 0.77
Identification and characterization of genes involved in leishmania pathogenesis: the potential for drug target selection. Mol Biol Int (2011) 0.77
Intracellular Survival of Leishmania major Depends on Uptake and Degradation of Extracellular Matrix Glycosaminoglycans by Macrophages. PLoS Pathog (2015) 0.77
MicroRNA expression profiling of Leishmania donovani-infected host cells uncovers the regulatory role of MIR30A-3p in host autophagy. Autophagy (2016) 0.76
Identification, characterization, and expression of a unique secretory lipase from the human pathogen Leishmania donovani. Mol Cell Biochem (2010) 0.76
Fast high yield of pure Leishmania (Leishmania) infantum axenic amastigotes and their infectivity to mouse macrophages. Parasitol Res (2009) 0.76
Universal minicircle sequence binding protein of Leishmania donovani regulates pathogenicity by controlling expression of cytochrome-b. Cell Biosci (2016) 0.76
Peripheral blood fibrocytes: new information to explain the dynamics of Leishmania infection. Mem Inst Oswaldo Cruz (2013) 0.75
Inhibition of the Rumen Ciliate Entodinium caudatum by Antibiotics. Front Microbiol (2017) 0.75
l-Arginine Uptake by Cationic Amino Acid Transporter Promotes Intra-Macrophage Survival of Leishmania donovani by Enhancing Arginase-Mediated Polyamine Synthesis. Front Immunol (2017) 0.75
MR1 presents microbial vitamin B metabolites to MAIT cells. Nature (2012) 3.71
Humans lack iGb3 due to the absence of functional iGb3-synthase: implications for NKT cell development and transplantation. PLoS Biol (2008) 2.08
Distinct protein classes including novel merozoite surface antigens in Raft-like membranes of Plasmodium falciparum. J Biol Chem (2005) 1.95
SMP-1, a member of a new family of small myristoylated proteins in kinetoplastid parasites, is targeted to the flagellum membrane in Leishmania. Mol Biol Cell (2004) 1.95
MyD88 is essential for clearance of Leishmania major: possible role for lipophosphoglycan and Toll-like receptor 2 signaling. Eur J Immunol (2003) 1.82
Mitochondrial metabolism of sexual and asexual blood stages of the malaria parasite Plasmodium falciparum. BMC Biol (2013) 1.46
PimE is a polyprenol-phosphate-mannose-dependent mannosyltransferase that transfers the fifth mannose of phosphatidylinositol mannoside in mycobacteria. J Biol Chem (2006) 1.36
Virulence of Leishmania major in macrophages and mice requires the gluconeogenic enzyme fructose-1,6-bisphosphatase. Proc Natl Acad Sci U S A (2006) 1.34
Evidence that intracellular beta1-2 mannan is a virulence factor in Leishmania parasites. J Biol Chem (2003) 1.34
Secondary acylation of Klebsiella pneumoniae lipopolysaccharide contributes to sensitivity to antibacterial peptides. J Biol Chem (2007) 1.33
LeishCyc: a biochemical pathways database for Leishmania major. BMC Syst Biol (2009) 1.32
Surface determinants of Leishmania parasites and their role in infectivity in the mammalian host. Curr Mol Med (2004) 1.31
A dynamic programming approach for the alignment of signal peaks in multiple gas chromatography-mass spectrometry experiments. BMC Bioinformatics (2007) 1.29
Mitochondrial metabolism of glucose and glutamine is required for intracellular growth of Toxoplasma gondii. Cell Host Microbe (2012) 1.22
Biosynthesis of mycobacterial phosphatidylinositol mannosides. Biochem J (2004) 1.22
The reductase that catalyzes mycolic motif synthesis is required for efficient attachment of mycolic acids to arabinogalactan. J Biol Chem (2007) 1.19
Modification of glycopeptidolipids by an O-methyltransferase of Mycobacterium smegmatis. Microbiology (2002) 1.15
Compartmentalization of lipid biosynthesis in mycobacteria. J Biol Chem (2005) 1.11
Function of phosphatidylinositol in mycobacteria. J Biol Chem (2005) 1.10
Molecular mimicry in Campylobacter jejuni: role of the lipo-oligosaccharide core oligosaccharide in inducing anti-ganglioside antibodies. FEMS Immunol Med Microbiol (2007) 1.10
Identification of a novel protein with a role in lipoarabinomannan biosynthesis in mycobacteria. J Biol Chem (2006) 1.09
Isotopomer profiling of Leishmania mexicana promastigotes reveals important roles for succinate fermentation and aspartate uptake in tricarboxylic acid cycle (TCA) anaplerosis, glutamate synthesis, and growth. J Biol Chem (2011) 1.09
Apicoplast and endoplasmic reticulum cooperate in fatty acid biosynthesis in apicomplexan parasite Toxoplasma gondii. J Biol Chem (2011) 1.09
PyMS: a Python toolkit for processing of gas chromatography-mass spectrometry (GC-MS) data. Application and comparative study of selected tools. BMC Bioinformatics (2012) 1.08
Analysis of a new mannosyltransferase required for the synthesis of phosphatidylinositol mannosides and lipoarbinomannan reveals two lipomannan pools in corynebacterineae. J Biol Chem (2008) 1.04
Systems biology: the next frontier for bioinformatics. Adv Bioinformatics (2011) 1.04
Intracellular trafficking of glycosylphosphatidylinositol (GPI)-anchored proteins and free GPIs in Leishmania mexicana. Biochem J (2002) 1.04
Comprehensive profiling and quantitation of amine group containing metabolites. Anal Chem (2011) 1.03
A unique thymic fibroblast population revealed by the monoclonal antibody MTS-15. J Immunol (2007) 1.03
Metabolomic analysis of trypanosomatid protozoa. Mol Biochem Parasitol (2011) 1.00
Atypical lipid composition in the purified relict plastid (apicoplast) of malaria parasites. Proc Natl Acad Sci U S A (2013) 1.00
Progressive peak clustering in GC-MS Metabolomic experiments applied to Leishmania parasites. Bioinformatics (2006) 0.99
Alveolate mitochondrial metabolic evolution: dinoflagellates force reassessment of the role of parasitism as a driver of change in apicomplexans. Mol Biol Evol (2012) 0.99
Evidence that intracellular stages of Leishmania major utilize amino sugars as a major carbon source. PLoS Pathog (2010) 0.97
Serum amyloid P colocalizes with apolipoproteins in human atheroma: functional implications. J Lipid Res (2007) 0.97
Mannose metabolism is required for mycobacterial growth. Biochem J (2003) 0.97
Chewing the fat on natural killer T cell development. J Exp Med (2006) 0.96
Oocyst wall formation and composition in coccidian parasites. Mem Inst Oswaldo Cruz (2009) 0.96
Methylation of GPLs in Mycobacterium smegmatis and Mycobacterium avium. J Bacteriol (2004) 0.95
Developmental changes in lysosome morphology and function Leishmania parasites. Int J Parasitol (2002) 0.95
Inositol lipid metabolism in mycobacteria: biosynthesis and regulatory mechanisms. Biochim Biophys Acta (2011) 0.92
Identification of plant-like galactolipids in Chromera velia, a photosynthetic relative of malaria parasites. J Biol Chem (2011) 0.92
The molecular basis of Leishmania pathogenesis. Int J Parasitol (2007) 0.92
Role of hexosamine biosynthesis in Leishmania growth and virulence. Mol Microbiol (2008) 0.90
Central carbon metabolism of Leishmania parasites. Parasitology (2010) 0.90
Leishmania beta-1,2-mannan is assembled on a mannose-cyclic phosphate primer. Proc Natl Acad Sci U S A (2006) 0.89
Direct evidence for ArO-S bond cleavage upon inactivation of Pseudomonas aeruginosa arylsulfatase by aryl sulfamates. Chembiochem (2008) 0.89
Calcineurin is required for Leishmania major stress response pathways and for virulence in the mammalian host. Mol Microbiol (2011) 0.89
Membrane protein SMP-1 is required for normal flagellum function in Leishmania. J Cell Sci (2010) 0.87
Recognition and detoxification of the insecticide DDT by Drosophila melanogaster glutathione S-transferase D1. J Mol Biol (2010) 0.85
Localization and activity of multidrug resistance protein 1 in the secretory pathway of Leishmania parasites. Mol Microbiol (2004) 0.84
Leishmania adaptor protein-1 subunits are required for normal lysosome traffic, flagellum biogenesis, lipid homeostasis, and adaptation to temperatures encountered in the mammalian host. Eukaryot Cell (2008) 0.84
More plastids in human parasites? Trends Parasitol (2004) 0.83
Acetylation of trehalose mycolates is required for efficient MmpL-mediated membrane transport in Corynebacterineae. ACS Chem Biol (2014) 0.83
Mutations in pimE restore lipoarabinomannan synthesis and growth in a Mycobacterium smegmatis lpqW mutant. J Bacteriol (2008) 0.83
Purification, characterization of O-acetylated sialoglycoconjugates-specific IgM, and development of an enzyme-linked immunosorbent assay for diagnosis and follow-up of indian visceral leishmaniasis patients. Diagn Microbiol Infect Dis (2004) 0.83
Stress-induced synthesis of phosphatidylinositol 3-phosphate in mycobacteria. J Biol Chem (2010) 0.82
A high-resolution solution structure of a trypanosomatid FYVE domain. Protein Sci (2007) 0.81
Plasmodium falciparum is dependent on de novo myo-inositol biosynthesis for assembly of GPI glycolipids and infectivity. Mol Microbiol (2014) 0.81
Characterization of a Leishmania mexicana mutant defective in synthesis of free and protein-linked GPI glycolipids. Mol Biochem Parasitol (2002) 0.80
Down-regulation of the trypanosomatid signal recognition particle affects the biogenesis of polytopic membrane proteins but not of signal peptide-containing proteins. Eukaryot Cell (2007) 0.80
A sample preparation protocol for 1H nuclear magnetic resonance studies of water-soluble metabolites in blood and urine. Anal Biochem (2009) 0.80
Acylation-dependent and-independent membrane targeting and distinct functions of small myristoylated proteins (SMPs) in Leishmania major. Int J Parasitol (2012) 0.80
Leishmania major methionine sulfoxide reductase A is required for resistance to oxidative stress and efficient replication in macrophages. PLoS One (2013) 0.80
Use of click chemistry to define the substrate specificity of Leishmania beta-1,2-mannosyltransferases. Chembiochem (2006) 0.80
Intracellular growth and pathogenesis of Leishmania parasites. Essays Biochem (2011) 0.80
Lysosomal degradation of Leishmania hexose and inositol transporters is regulated in a stage-, nutrient- and ubiquitin-dependent manner. Int J Parasitol (2011) 0.79
Cyanogenic glycosides from the rare Australian endemic rainforest tree Clerodendrum grayi (Lamiaceae). Phytochemistry (2005) 0.78
Synthesis, structural elucidation, and biochemical analysis of immunoactive glucuronosyl diacylglycerides of mycobacteria and corynebacteria. J Org Chem (2013) 0.78
(1)H-NMR analysis of the human urinary metabolome in response to an 18-month multi-component exercise program and calcium-vitamin-D3 supplementation in older men. Appl Physiol Nutr Metab (2014) 0.77
LeishCyc: a guide to building a metabolic pathway database and visualization of metabolomic data. Methods Mol Biol (2012) 0.77
Galactose-derived phosphonate analogues as potential inhibitors of phosphatidylinositol biosynthesis in mycobacteria. Org Biomol Chem (2007) 0.76
The lipoprotein LpqW is essential for the mannosylation of periplasmic glycolipids in Corynebacteria. J Biol Chem (2012) 0.76
Membrane targeting of the small myristoylated protein 2 (SMP-2) in Leishmania major. Mol Biochem Parasitol (2013) 0.75
Use of (13)C stable isotope labelling for pathway and metabolic flux analysis in Leishmania parasites. Methods Mol Biol (2015) 0.75
Discovery of inhibitors of Leishmania β-1,2-mannosyltransferases using a click-chemistry-derived guanosine monophosphate library. PLoS One (2012) 0.75
Letter to the glycoforum transforming glycoscience: an Australian perspective. Glycobiology (2014) 0.75
1H, 13C and 15N resonance assignments of SMP-1: a small myristoylated protein from Leishmania major. J Biomol NMR (2006) 0.75