Published in Neuroreport on November 19, 2007
Meta-analysis of the association between variants in SORL1 and Alzheimer disease. Arch Neurol (2011) 1.59
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Loss of LR11/SORLA enhances early pathology in a mouse model of amyloidosis: evidence for a proximal role in Alzheimer's disease. J Neurosci (2008) 1.39
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Validating predicted biological effects of Alzheimer's disease associated SNPs using CSF biomarker levels. J Alzheimers Dis (2010) 1.24
Association of distinct variants in SORL1 with cerebrovascular and neurodegenerative changes related to Alzheimer disease. Arch Neurol (2008) 1.16
Omega-3 fatty acids and dementia. Prostaglandins Leukot Essent Fatty Acids (2009) 1.15
Maternal transmission of Alzheimer's disease: prodromal metabolic phenotype and the search for genes. Hum Genomics (2010) 1.12
Coding mutations in SORL1 and Alzheimer disease. Ann Neurol (2015) 1.09
No association of SORL1 SNPs with Alzheimer's disease. Neurosci Lett (2008) 1.08
Expression of SORL1 and a novel SORL1 splice variant in normal and Alzheimers disease brain. Mol Neurodegener (2009) 1.06
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Use of genetic variation as biomarkers for mild cognitive impairment and progression of mild cognitive impairment to dementia. J Alzheimers Dis (2010) 0.93
Impact of SORL1 single nucleotide polymorphisms on Alzheimer's disease cerebrospinal fluid markers. Dement Geriatr Cogn Disord (2011) 0.93
The neuronal sortilin-related receptor gene SORL1 and late-onset Alzheimer's disease. Curr Neurol Neurosci Rep (2008) 0.92
The SORL1 gene and convergent neural risk for Alzheimer's disease across the human lifespan. Mol Psychiatry (2013) 0.90
Sortilin receptor 1 predicts longitudinal cognitive change. Neurobiol Aging (2013) 0.89
Possible association between SORL1 and Alzheimer disease? Reanalysing the data of Shibata et al. Dement Geriatr Cogn Disord (2008) 0.89
Independent and epistatic effects of variants in VPS10-d receptors on Alzheimer disease risk and processing of the amyloid precursor protein (APP). Transl Psychiatry (2013) 0.88
SORL1 genetic variants and cerebrospinal fluid biomarkers of Alzheimer’s disease. Eur Arch Psychiatry Clin Neurosci (2012) 0.87
Dyslipidemia and the risk of Alzheimer's disease. Curr Atheroscler Rep (2013) 0.85
The Alzheimer's associated 5' region of the SORL1 gene cis regulates SORL1 transcripts expression. Neurobiol Aging (2010) 0.85
Dyslipidemia and dementia: current epidemiology, genetic evidence, and mechanisms behind the associations. J Alzheimers Dis (2012) 0.85
Genomics of Dementia: APOE- and CYP2D6-Related Pharmacogenetics. Int J Alzheimers Dis (2012) 0.81
The role of the retromer complex in aging-related neurodegeneration: a molecular and genomic review. Mol Genet Genomics (2014) 0.81
Lessons from epidemiologic research about risk factors, modifiers, and progression of late onset Alzheimer's Disease in New York City at Columbia University Medical Center. J Alzheimers Dis (2013) 0.80
Biological changes associated with healthy versus pathological aging: a symposium review. Ageing Res Rev (2009) 0.80
Panel of Genetic Variations as a Potential Non-invasive Biomarker for Early Diagnosis of Alzheimer's Disease. Clin Psychopharmacol Neurosci (2011) 0.79
Use of genetic variation as biomarkers for Alzheimer's disease. Ann N Y Acad Sci (2009) 0.79
Impact of SORL1 genetic variations on MRI markers in non-demented elders. Oncotarget (2016) 0.78
Single-nucleotide polymorphisms of GSK3B, GAB2 and SORL1 in late-onset Alzheimer's disease: interactions with the APOE genotype. Clinics (Sao Paulo) (2013) 0.78
Brain traffic: subcellular transport of the amyloid precursor protein. Arch Neurol (2009) 0.78
SORL1 rs1699102 polymorphism modulates age-related cognitive decline and gray matter volume reduction in non-demented individuals. Eur J Neurol (2016) 0.75
Neuronal LR11 expression does not differentiate between clinically-defined Alzheimer's disease and control brains. PLoS One (2012) 0.75
SORL1 variants across Alzheimer's disease European American cohorts. Eur J Hum Genet (2016) 0.75
Sex moderates the effects of the Sorl1 gene rs2070045 polymorphism on cognitive impairment and disruption of the cingulum integrity in healthy elderly. Neuropsychopharmacology (2015) 0.75
Functional Roles of the Interaction of APP and Lipoprotein Receptors. Front Mol Neurosci (2017) 0.75
SORL1 mutations in early- and late-onset Alzheimer disease. Neurol Genet (2016) 0.75
PLINK: a tool set for whole-genome association and population-based linkage analyses. Am J Hum Genet (2007) 209.92
Haploview: analysis and visualization of LD and haplotype maps. Bioinformatics (2004) 125.23
The neuronal sortilin-related receptor SORL1 is genetically associated with Alzheimer disease. Nat Genet (2007) 9.80
GAB2 alleles modify Alzheimer's risk in APOE epsilon4 carriers. Neuron (2007) 6.88
The association between genetic variants in SORL1 and Alzheimer disease in an urban, multiethnic, community-based cohort. Arch Neurol (2007) 2.21
The diagnosis of dementia due to Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease. Alzheimers Dement (2011) 24.26
Complement factor H polymorphism and age-related macular degeneration. Science (2005) 17.79
Clinical and biomarker changes in dominantly inherited Alzheimer's disease. N Engl J Med (2012) 14.14
TREM2 variants in Alzheimer's disease. N Engl J Med (2012) 11.35
Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease. Nat Genet (2011) 10.07
The neuronal sortilin-related receptor SORL1 is genetically associated with Alzheimer disease. Nat Genet (2007) 9.80
Genome-wide analysis of genetic loci associated with Alzheimer disease. JAMA (2010) 9.52
Cytoreductive antitumor activity of PF-2341066, a novel inhibitor of anaplastic lymphoma kinase and c-Met, in experimental models of anaplastic large-cell lymphoma. Mol Cancer Ther (2007) 7.08
Disclosure of APOE genotype for risk of Alzheimer's disease. N Engl J Med (2009) 6.43
An orally available small-molecule inhibitor of c-Met, PF-2341066, exhibits cytoreductive antitumor efficacy through antiproliferative and antiangiogenic mechanisms. Cancer Res (2007) 5.63
Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions. Nat Genet (2010) 5.52
Protective variant for hippocampal atrophy identified by whole exome sequencing. Ann Neurol (2015) 5.10
Apolipoprotein E, Alzheimer disease, and African Americans. Arch Neurol (2003) 4.63
Mediterranean diet and risk for Alzheimer's disease. Ann Neurol (2006) 4.38
A meta-analysis of estimated genetic and environmental effects on smoking behavior in male and female adult twins. Addiction (2003) 4.37
Genetic variants near TIMP3 and high-density lipoprotein-associated loci influence susceptibility to age-related macular degeneration. Proc Natl Acad Sci U S A (2010) 4.30
The PhenX Toolkit: get the most from your measures. Am J Epidemiol (2011) 4.19
Epidemiology of Alzheimer disease. Nat Rev Neurol (2011) 4.13
Seven new loci associated with age-related macular degeneration. Nat Genet (2013) 3.81
Hypertension and the risk of mild cognitive impairment. Arch Neurol (2007) 3.62
A summary risk score for the prediction of Alzheimer disease in elderly persons. Arch Neurol (2010) 3.52
Stroke and the risk of Alzheimer disease. Arch Neurol (2003) 3.49
Mediterranean diet and mild cognitive impairment. Arch Neurol (2009) 3.40
Frequency and course of mild cognitive impairment in a multiethnic community. Ann Neurol (2008) 3.39
Retracted Integrative genomics identifies APOE ε4 effectors in Alzheimer's disease. Nature (2013) 3.35
Imaging hippocampal function across the human life span: is memory decline normal or not? Ann Neurol (2002) 3.34
Risk of dementia among white and African American relatives of patients with Alzheimer disease. JAMA (2002) 3.16
Rare variants in APP, PSEN1 and PSEN2 increase risk for AD in late-onset Alzheimer's disease families. PLoS One (2012) 3.11
Differential modulation of endotoxin responsiveness by human caspase-12 polymorphisms. Nature (2004) 2.98
Mediterranean diet, Alzheimer disease, and vascular mediation. Arch Neurol (2006) 2.98
Meta-analysis confirms CR1, CLU, and PICALM as alzheimer disease risk loci and reveals interactions with APOE genotypes. Arch Neurol (2010) 2.91
Alcohol intake and risk of dementia. J Am Geriatr Soc (2004) 2.90
Pilot association study of the beta-glucocerebrosidase N370S allele and Parkinson's disease in subjects of Jewish ethnicity. Mov Disord (2005) 2.88
Hyperinsulinemia and risk of Alzheimer disease. Neurology (2004) 2.87
Relation of diabetes to mild cognitive impairment. Arch Neurol (2007) 2.86
Estimating risk curves for first-degree relatives of patients with Alzheimer's disease: the REVEAL study. Genet Med (2004) 2.82
Alzheimer's Disease Neuroimaging Initiative biomarkers as quantitative phenotypes: Genetics core aims, progress, and plans. Alzheimers Dement (2010) 2.79
Atherosclerosis and AD: analysis of data from the US National Alzheimer's Coordinating Center. Neurology (2005) 2.76
Reversal of autophagy dysfunction in the TgCRND8 mouse model of Alzheimer's disease ameliorates amyloid pathologies and memory deficits. Brain (2011) 2.76
Brain morphology in older African Americans, Caribbean Hispanics, and whites from northern Manhattan. Arch Neurol (2008) 2.69
Variants in the ATP-binding cassette transporter (ABCA7), apolipoprotein E ϵ4,and the risk of late-onset Alzheimer disease in African Americans. JAMA (2013) 2.58
TMP21 is a presenilin complex component that modulates gamma-secretase but not epsilon-secretase activity. Nature (2006) 2.56
A genomewide screen of 345 families for autism-susceptibility loci. Am J Hum Genet (2003) 2.51
Fetal hemoglobin in sickle cell anemia: genome-wide association studies suggest a regulatory region in the 5' olfactory receptor gene cluster. Blood (2009) 2.50
Mediterranean diet and Alzheimer disease mortality. Neurology (2007) 2.45
Who seeks genetic susceptibility testing for Alzheimer's disease? Findings from a multisite, randomized clinical trial. Genet Med (2004) 2.44
Implementing diagnostic criteria and estimating frequency of mild cognitive impairment in an urban community. Arch Neurol (2005) 2.39
A network model to predict the risk of death in sickle cell disease. Blood (2007) 2.39
Cyclohexanehexol inhibitors of Abeta aggregation prevent and reverse Alzheimer phenotype in a mouse model. Nat Med (2006) 2.28
Caloric intake and the risk of Alzheimer disease. Arch Neurol (2002) 2.28
Wild-type PINK1 prevents basal and induced neuronal apoptosis, a protective effect abrogated by Parkinson disease-related mutations. J Biol Chem (2005) 2.26
Brain expression genome-wide association study (eGWAS) identifies human disease-associated variants. PLoS Genet (2012) 2.23
The association between genetic variants in SORL1 and Alzheimer disease in an urban, multiethnic, community-based cohort. Arch Neurol (2007) 2.21
Shorter telomeres are associated with mortality in those with APOE epsilon4 and dementia. Ann Neurol (2006) 2.21
Meta-analysis of Parkinson's disease: identification of a novel locus, RIT2. Ann Neurol (2012) 2.20
Antioxidant vitamin intake and risk of Alzheimer disease. Arch Neurol (2003) 2.20
Association of granulomatosis with polyangiitis (Wegener's) with HLA-DPB1*04 and SEMA6A gene variants: evidence from genome-wide analysis. Arthritis Rheum (2013) 2.17
Interaction of FKBP5 with childhood adversity on risk for post-traumatic stress disorder. Neuropsychopharmacology (2010) 2.16
GWAS of cerebrospinal fluid tau levels identifies risk variants for Alzheimer's disease. Neuron (2013) 2.13
HGF/c-Met acts as an alternative angiogenic pathway in sunitinib-resistant tumors. Cancer Res (2010) 2.11
Relation of plasma lipids to Alzheimer disease and vascular dementia. Arch Neurol (2004) 2.09
Novel late-onset Alzheimer disease loci variants associate with brain gene expression. Neurology (2012) 2.08
Association of glucocerebrosidase mutations with dementia with lewy bodies. Arch Neurol (2009) 2.06
Validity of self-reported stroke in elderly African Americans, Caribbean Hispanics, and Whites. Arch Neurol (2009) 2.05
Microbleed topography, leukoaraiosis, and cognition in probable Alzheimer disease from the Sunnybrook dementia study. Arch Neurol (2008) 2.03
Genome-wide association of familial late-onset Alzheimer's disease replicates BIN1 and CLU and nominates CUGBP2 in interaction with APOE. PLoS Genet (2011) 2.02
SORCS1 alters amyloid precursor protein processing and variants may increase Alzheimer's disease risk. Ann Neurol (2011) 2.01
Cardiovascular risk factors and Alzheimer's disease. Curr Atheroscler Rep (2004) 2.00
Analysis of the glucocerebrosidase gene in Parkinson's disease. Mov Disord (2005) 1.99
Comprehensive search for Alzheimer disease susceptibility loci in the APOE region. Arch Neurol (2012) 1.97
The brain in the age of old: the hippocampal formation is targeted differentially by diseases of late life. Ann Neurol (2008) 1.92
Association of higher levels of high-density lipoprotein cholesterol in elderly individuals and lower risk of late-onset Alzheimer disease. Arch Neurol (2010) 1.91
Dietary factors and Alzheimer's disease. Lancet Neurol (2004) 1.90
Developing an international network for Alzheimer research: The Dominantly Inherited Alzheimer Network. Clin Investig (Lond) (2012) 1.90
Measures of adiposity and dementia risk in elderly persons. Arch Neurol (2007) 1.88
Novel splicing mutation in the progranulin gene causing familial corticobasal syndrome. Brain (2006) 1.86
Hemolysis-associated priapism in sickle cell disease. Blood (2005) 1.86