Published in Proc Natl Acad Sci U S A on September 26, 2011
Epistasis and quantitative traits: using model organisms to study gene-gene interactions. Nat Rev Genet (2013) 2.73
What is complex about complex disorders? Genome Biol (2012) 1.00
Epistatic interactions attenuate mutations affecting startle behaviour in Drosophila melanogaster. Genet Res (Camb) (2009) 0.96
P1 interneurons promote a persistent internal state that enhances inter-male aggression in Drosophila. Elife (2015) 0.95
Volatile Drosophila cuticular pheromones are affected by social but not sexual experience. PLoS One (2012) 0.92
High intake of dietary sugar enhances bisphenol A (BPA) disruption and reveals ribosome-mediated pathways of toxicity. Genetics (2014) 0.91
Genetics and neurobiology of aggression in Drosophila. Fly (Austin) (2012) 0.91
Extensive epistasis for olfactory behaviour, sleep and waking activity in Drosophila melanogaster. Genet Res (Camb) (2012) 0.88
Hearing regulates Drosophila aggression. Proc Natl Acad Sci U S A (2017) 0.85
Genetic architecture of natural variation in Drosophila melanogaster aggressive behavior. Proc Natl Acad Sci U S A (2015) 0.82
Mood stabilizing drugs regulate transcription of immune, neuronal and metabolic pathway genes in Drosophila. Psychopharmacology (Berl) (2016) 0.79
Genetic architecture of natural variation in visual senescence in Drosophila. Proc Natl Acad Sci U S A (2016) 0.76
The genetic basis of natural variation in mushroom body size in Drosophila melanogaster. Nat Commun (2015) 0.76
Genetics of adverse reactions to haloperidol in a mouse diallel: a drug-placebo experiment and Bayesian causal analysis. Genetics (2013) 0.76
Sound and fury: Modulation of aggressive behavior through acoustic signals. Proc Natl Acad Sci U S A (2017) 0.75
Extensive reorganization of behavior accompanies ontogeny of aggression in male flesh flies. PLoS One (2014) 0.75
Dissecting the Genetic Architecture of Behavior in Drosophila melanogaster. Curr Opin Behav Sci (2015) 0.75
Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nat Protoc (2009) 137.99
Statistical significance for genomewide studies. Proc Natl Acad Sci U S A (2003) 88.64
Finding the missing heritability of complex diseases. Nature (2009) 67.95
Influence of life stress on depression: moderation by a polymorphism in the 5-HTT gene. Science (2003) 28.61
Role of genotype in the cycle of violence in maltreated children. Science (2002) 13.50
Epistasis--the essential role of gene interactions in the structure and evolution of genetic systems. Nat Rev Genet (2008) 9.26
Data and theory point to mainly additive genetic variance for complex traits. PLoS Genet (2008) 7.15
The genetics of quantitative traits: challenges and prospects. Nat Rev Genet (2009) 5.99
Aggressive behavior and altered amounts of brain serotonin and norepinephrine in mice lacking MAOA. Science (1995) 4.59
The pleiotropic structure of the genotype-phenotype map: the evolvability of complex organisms. Nat Rev Genet (2011) 3.57
Behavioural abnormalities in male mice lacking neuronal nitric oxide synthase. Nature (1995) 3.15
Epistasis and the release of genetic variation during long-term selection. Nat Genet (2006) 2.81
A subset of octopaminergic neurons are important for Drosophila aggression. Nat Neurosci (2008) 2.64
Serotonin and neuropeptide F have opposite modulatory effects on fly aggression. Nat Genet (2007) 2.48
Enhanced aggressive behavior in mice lacking 5-HT1B receptor. Science (1994) 2.32
Molecular analysis of flies selected for aggressive behavior. Nat Genet (2006) 2.29
Quantitative genomics of aggressive behavior in Drosophila melanogaster. PLoS Genet (2006) 2.17
Recent advances in the study of the biosynthesis and functions of sulfated glycosaminoglycans. Curr Opin Struct Biol (2000) 2.01
Identification of an aggression-promoting pheromone and its receptor neurons in Drosophila. Nature (2009) 1.96
Dynamic genetic interactions determine odor-guided behavior in Drosophila melanogaster. Genetics (2006) 1.88
The genetic architecture of odor-guided behavior in Drosophila: epistasis and the transcriptome. Nat Genet (2003) 1.85
fruitless regulates aggression and dominance in Drosophila. Nat Neurosci (2006) 1.78
Social and neural determinants of aggressive behavior: pharmacotherapeutic targets at serotonin, dopamine and gamma-aminobutyric acid systems. Psychopharmacology (Berl) (2002) 1.73
Drosophila as a new model organism for the neurobiology of aggression? J Exp Biol (2002) 1.53
Neurogenetic networks for startle-induced locomotion in Drosophila melanogaster. Proc Natl Acad Sci U S A (2008) 1.51
Valproate regulates GSK-3-mediated axonal remodeling and synapsin I clustering in developing neurons. Mol Cell Neurosci (2002) 1.47
A newly uncovered phenotype associated with the fruitless gene of Drosophila melanogaster: aggression-like head interactions between mutant males. Behav Genet (2000) 1.44
Serotonin and aggression: insights gained from a lobster model system and speculations on the role of amine neurons in a complex behavior. J Comp Physiol A (2000) 1.41
Epistatic interactions between smell-impaired loci in Drosophila melanogaster. Genetics (1998) 1.26
Genetics of human aggressive behaviour. Hum Genet (2009) 1.20
Review of evidence for genetic testing for CYP450 polymorphisms in management of patients with nonpsychotic depression with selective serotonin reuptake inhibitors. Genet Med (2007) 1.17
Serotonin 5-HT(2) and 5-HT(1A)-like receptors differentially modulate aggressive behaviors in Drosophila melanogaster. Neuroscience (2008) 1.15
Mutations in many genes affect aggressive behavior in Drosophila melanogaster. BMC Biol (2009) 1.14
Quantitative and molecular genetic analyses of mutations increasing Drosophila life span. PLoS Genet (2010) 1.14
Pharmacological evidence for GABAergic regulation of specific behaviors in Drosophila melanogaster. J Neurobiol (2002) 1.13
Pleiotropic fitness effects of the Tre1-Gr5a region in Drosophila melanogaster. Nat Genet (2006) 1.10
Aggression in male mice lacking functional estrogen receptor alpha. Behav Neurosci (2003) 1.10
Quantitative trait loci for aggressive behavior in Drosophila melanogaster. Genetics (2009) 1.08
Reduced aggression in mice lacking the serotonin transporter. Psychopharmacology (Berl) (2002) 1.08
Increased intermale aggression and neuroendocrine response in mice deficient for the neural cell adhesion molecule (NCAM). Eur J Neurosci (1997) 1.03
Prefrontal and amygdala volumes are related to adolescents' affective behaviors during parent-adolescent interactions. Proc Natl Acad Sci U S A (2008) 0.99
Pleiotropic effects of Drosophila neuralized on complex behaviors and brain structure. Genetics (2008) 0.98
Clinical applications of pharmacogenetics in psychiatry. Psychopharmacology (Berl) (2002) 0.84
Finding the missing heritability of complex diseases. Nature (2009) 67.95
The Drosophila melanogaster Genetic Reference Panel. Nature (2012) 7.94
Systems genetics of complex traits in Drosophila melanogaster. Nat Genet (2009) 5.41
Genetic architecture of quantitative traits in mice, flies, and humans. Genome Res (2009) 4.62
Disrupted function and axonal distribution of mutant tyrosyl-tRNA synthetase in dominant intermediate Charcot-Marie-Tooth neuropathy. Nat Genet (2006) 3.04
Using whole-genome sequence data to predict quantitative trait phenotypes in Drosophila melanogaster. PLoS Genet (2012) 2.90
Does evolutionary theory need a rethink? Nature (2014) 2.82
Epistasis dominates the genetic architecture of Drosophila quantitative traits. Proc Natl Acad Sci U S A (2012) 2.59
Dopa decarboxylase (Ddc) affects variation in Drosophila longevity. Nat Genet (2003) 2.56
Of flies and man: Drosophila as a model for human complex traits. Annu Rev Genomics Hum Genet (2006) 2.47
Speed-mapping quantitative trait loci using microarrays. Nat Methods (2007) 2.26
Quantitative genomics of aggressive behavior in Drosophila melanogaster. PLoS Genet (2006) 2.17
Genotype-environment interactions at quantitative trait loci affecting inflorescence development in Arabidopsis thaliana. Genetics (2003) 1.92
Dynamic genetic interactions determine odor-guided behavior in Drosophila melanogaster. Genetics (2006) 1.88
The genetic architecture of odor-guided behavior in Drosophila: epistasis and the transcriptome. Nat Genet (2003) 1.85
Quantitative trait loci for inflorescence development in Arabidopsis thaliana. Genetics (2002) 1.84
Quantitative trait loci affecting starvation resistance in Drosophila melanogaster. Genetics (2004) 1.76
Quantitative trait loci affecting natural variation in Drosophila longevity. Mech Ageing Dev (2004) 1.75
Quantitative genetic analyses of complex behaviours in Drosophila. Nat Rev Genet (2004) 1.67
Quantitative genomics of locomotor behavior in Drosophila melanogaster. Genome Biol (2007) 1.64
Novel loci control variation in reproductive timing in Arabidopsis thaliana in natural environments. Genetics (2002) 1.63
Co-regulated transcriptional networks contribute to natural genetic variation in Drosophila sleep. Nat Genet (2009) 1.59
miRNA genes and the brain: implications for psychiatric disorders. Hum Mutat (2010) 1.55
Aberrant lysosomal carbohydrate storage accompanies endocytic defects and neurodegeneration in Drosophila benchwarmer. J Cell Biol (2005) 1.52
Neurogenetic networks for startle-induced locomotion in Drosophila melanogaster. Proc Natl Acad Sci U S A (2008) 1.51
Phenotypic variation and natural selection at catsup, a pleiotropic quantitative trait gene in Drosophila. Curr Biol (2006) 1.49
hairy: A quantitative trait locus for drosophila sensory bristle number. Genetics (2002) 1.48
Heterogeneous selection at specific loci in natural environments in Arabidopsis thaliana. Genetics (2003) 1.44
The genetic architecture of Drosophila sensory bristle number. Genetics (2002) 1.41
Population genomics of the Wolbachia endosymbiont in Drosophila melanogaster. PLoS Genet (2012) 1.37
Quantitative genomics of starvation stress resistance in Drosophila. Genome Biol (2005) 1.37
Genomic variation and its impact on gene expression in Drosophila melanogaster. PLoS Genet (2012) 1.31
Cephalopod Hox genes and the origin of morphological novelties. Nature (2003) 1.29
The quantitative genetic basis of male mating behavior in Drosophila melanogaster. Genetics (2004) 1.28
Phenotypic and transcriptional response to selection for alcohol sensitivity in Drosophila melanogaster. Genome Biol (2007) 1.27
Quantitative trait loci for locomotor behavior in Drosophila melanogaster. Genetics (2006) 1.26
Phenotypic plasticity of the Drosophila transcriptome. PLoS Genet (2012) 1.26
Candidate genes affecting Drosophila life span identified by integrating microarray gene expression analysis and QTL mapping. Mech Ageing Dev (2006) 1.25
Expanding roles for AMP-activated protein kinase in neuronal survival and autophagy. Bioessays (2009) 1.23
Transcriptional response to alcohol exposure in Drosophila melanogaster. Genome Biol (2006) 1.21
Dominant mutations in the tyrosyl-tRNA synthetase gene recapitulate in Drosophila features of human Charcot-Marie-Tooth neuropathy. Proc Natl Acad Sci U S A (2009) 1.21
Automated protein-DNA interaction screening of Drosophila regulatory elements. Nat Methods (2011) 1.21
Gene-environment contributions to the development of infant vagal reactivity: the interaction of dopamine and maternal sensitivity. Child Dev (2008) 1.20
Vanaso is a candidate quantitative trait gene for Drosophila olfactory behavior. Genetics (2002) 1.20
Plasticity of the chemoreceptor repertoire in Drosophila melanogaster. PLoS Genet (2009) 1.18
Quantitative trait loci for sexual isolation between Drosophila simulans and D. mauritiana. Genetics (2004) 1.18
Quantitative trait loci with age-specific effects on fecundity in Drosophila melanogaster. Genetics (2005) 1.17
Association of polymorphisms in odorant-binding protein genes with variation in olfactory response to benzaldehyde in Drosophila. Genetics (2007) 1.17
Quantitative trait loci affecting the difference in pigmentation between Drosophila yakuba and D. santomea. Genetics (2005) 1.16
Mutations in many genes affect aggressive behavior in Drosophila melanogaster. BMC Biol (2009) 1.14
Genome-wide association analysis of oxidative stress resistance in Drosophila melanogaster. PLoS One (2012) 1.14
Quantitative and molecular genetic analyses of mutations increasing Drosophila life span. PLoS Genet (2010) 1.14
Impaired olfactory behavior in mice deficient in the alpha subunit of G(o). Brain Res (2002) 1.13
The DSC1 channel, encoded by the smi60E locus, contributes to odor-guided behavior in Drosophila melanogaster. Genetics (2002) 1.13
Genome-wide association study of sleep in Drosophila melanogaster. BMC Genomics (2013) 1.11
Phenotypic plasticity and genotype by environment interaction for olfactory behavior in Drosophila melanogaster. Genetics (2008) 1.11
Pleiotropic fitness effects of the Tre1-Gr5a region in Drosophila melanogaster. Nat Genet (2006) 1.10
No evidence for an association between common nonsynonymous polymorphisms in delta and bristle number variation in natural and laboratory populations of Drosophila melanogaster. Genetics (2004) 1.10
The complex genetic architecture of Drosophila life span. Exp Aging Res (2002) 1.09
The genetic basis of postzygotic reproductive isolation between Drosophila santomea and D. yakuba due to hybrid male sterility. Genetics (2006) 1.09
Quantitative trait loci for aggressive behavior in Drosophila melanogaster. Genetics (2009) 1.08
Analysis of natural variation reveals neurogenetic networks for Drosophila olfactory behavior. Proc Natl Acad Sci U S A (2012) 1.08
AMP-activated protein kinase (AMPK) molecular crossroad for metabolic control and survival of neurons. Neuroscientist (2009) 1.08
Genome-wide association for sensitivity to chronic oxidative stress in Drosophila melanogaster. PLoS One (2012) 1.07
Overexpression of myocilin in the Drosophila eye activates the unfolded protein response: implications for glaucoma. PLoS One (2009) 1.06
Olfactomedin-2 mediates development of the anterior central nervous system and head structures in zebrafish. Mech Dev (2007) 1.06
Natural variation, functional pleiotropy and transcriptional contexts of odorant binding protein genes in Drosophila melanogaster. Genetics (2010) 1.02