Published in PLoS Biol on December 01, 2005
Population genomics of parallel adaptation in threespine stickleback using sequenced RAD tags. PLoS Genet (2010) 7.05
Localizing recent adaptive evolution in the human genome. PLoS Genet (2007) 5.11
Large-scale turnover of functional transcription factor binding sites in Drosophila. PLoS Comput Biol (2006) 4.01
Human-specific gain of function in a developmental enhancer. Science (2008) 3.84
Evolution of the mammalian transcription factor binding repertoire via transposable elements. Genome Res (2008) 3.76
A new approach for using genome scans to detect recent positive selection in the human genome. PLoS Biol (2007) 3.71
Emerging principles of regulatory evolution. Proc Natl Acad Sci U S A (2007) 3.42
Forces shaping the fastest evolving regions in the human genome. PLoS Genet (2006) 3.32
The evolution of mammalian gene families. PLoS One (2006) 3.04
Stepwise modification of a modular enhancer underlies adaptation in a Drosophila population. Science (2009) 2.77
The dynorphin/kappa opioid system as a modulator of stress-induced and pro-addictive behaviors. Brain Res (2009) 2.61
Transcriptional architecture of the primate neocortex. Neuron (2012) 2.42
More genes underwent positive selection in chimpanzee evolution than in human evolution. Proc Natl Acad Sci U S A (2007) 2.00
A genome-wide study of DNA methylation patterns and gene expression levels in multiple human and chimpanzee tissues. PLoS Genet (2011) 1.92
Kinase cascades and ligand-directed signaling at the kappa opioid receptor. Psychopharmacology (Berl) (2010) 1.90
Gene regulation in primates evolves under tissue-specific selection pressures. PLoS Genet (2008) 1.86
Adaptive evolution of young gene duplicates in mammals. Genome Res (2009) 1.82
Gene expression levels are a target of recent natural selection in the human genome. Mol Biol Evol (2008) 1.63
Identification of the REST regulon reveals extensive transposable element-mediated binding site duplication. Nucleic Acids Res (2006) 1.62
Polymorphisms affecting gene transcription and mRNA processing in pharmacogenetic candidate genes: detection through allelic expression imbalance in human target tissues. Pharmacogenet Genomics (2008) 1.51
The origins of novel protein interactions during animal opsin evolution. PLoS One (2007) 1.50
Adaptive evolution of conserved noncoding elements in mammals. PLoS Genet (2007) 1.45
A genome-wide signature of positive selection in ancient and recent invasive expansions of the honey bee Apis mellifera. Proc Natl Acad Sci U S A (2008) 1.30
Genetic basis of human brain evolution. Trends Neurosci (2008) 1.22
Gene expression differences among primates are associated with changes in a histone epigenetic modification. Genetics (2011) 1.20
Using reporter gene assays to identify cis regulatory differences between humans and chimpanzees. Genetics (2007) 1.18
The jewels of our genome: the search for the genomic changes underlying the evolutionarily unique capacities of the human brain. PLoS Genet (2006) 1.12
A genome-wide screen for noncoding elements important in primate evolution. BMC Evol Biol (2008) 1.12
Patterns of population differentiation of candidate genes for cardiovascular disease. BMC Genet (2007) 1.09
A combination of genomic approaches reveals the role of FOXO1a in regulating an oxidative stress response pathway. PLoS One (2008) 1.08
Population structure in a comprehensive genomic data set on human microsatellite variation. G3 (Bethesda) (2013) 1.05
The genetics of the opioid system and specific drug addictions. Hum Genet (2012) 1.04
Opioid neuropeptide genotypes in relation to heroin abuse: dopamine tone contributes to reversed mesolimbic proenkephalin expression. Proc Natl Acad Sci U S A (2008) 1.03
Human genomic disease variants: a neutral evolutionary explanation. Genome Res (2012) 1.02
Reconstructing phylogenies and phenotypes: a molecular view of human evolution. J Anat (2008) 1.01
Disparities in allele frequencies and population differentiation for 101 disease-associated single nucleotide polymorphisms between Puerto Ricans and non-Hispanic whites. BMC Genet (2009) 1.01
Primate-specific evolution of an LDLR enhancer. Genome Biol (2006) 0.94
Complex signatures of selection for the melanogenic loci TYR, TYRP1 and DCT in humans. BMC Evol Biol (2008) 0.93
Adaptive variation regulates the expression of the human SGK1 gene in response to stress. PLoS Genet (2009) 0.93
Primate TNF promoters reveal markers of phylogeny and evolution of innate immunity. PLoS One (2007) 0.92
Coevolution within and between regulatory loci can preserve promoter function despite evolutionary rate acceleration. PLoS Genet (2012) 0.92
The impact of cis-acting polymorphisms on the human phenotype. Hugo J (2011) 0.91
Epigenetic modifications are associated with inter-species gene expression variation in primates. Genome Biol (2014) 0.90
GC-biased evolution near human accelerated regions. PLoS Genet (2010) 0.89
A panel of induced pluripotent stem cells from chimpanzees: a resource for comparative functional genomics. Elife (2015) 0.88
Microsatellites as targets of natural selection. Mol Biol Evol (2012) 0.88
Tempo and mode in the endocannaboinoid system. J Mol Evol (2007) 0.84
Dynamic up-regulation of prodynorphin transcription in temporal lobe epilepsy. Hippocampus (2009) 0.84
Cell-specific effects of variants of the 68-base pair tandem repeat on prodynorphin gene promoter activity. Addict Biol (2010) 0.84
Evolution of candidate transcriptional regulatory motifs since the human-chimpanzee divergence. Genome Biol (2006) 0.83
Fast evolution from precast bricks: genomics of young freshwater populations of threespine stickleback Gasterosteus aculeatus. PLoS Genet (2014) 0.82
Association of orthodenticle with natural variation for early embryonic patterning in Drosophila melanogaster. J Exp Zool B Mol Dev Evol (2009) 0.82
Evolutionary forces shaping genomic islands of population differentiation in humans. BMC Genomics (2012) 0.82
Patterns of variation in DNA segments upstream of transcription start sites. Hum Mutat (2007) 0.80
A selection index for gene expression evolution and its application to the divergence between humans and chimpanzees. PLoS One (2012) 0.79
Evidence that purifying selection acts on promoter sequences. Genetics (2011) 0.79
Cis-regulatory elements and human evolution. Curr Opin Genet Dev (2014) 0.78
Small changes, big results: evolution of morphological discontinuity in mammals. J Biol (2008) 0.78
Assessing the genome-wide effect of promoter region tandem repeat natural variation on gene expression. G3 (Bethesda) (2012) 0.78
Naturally occurring deletions of hunchback binding sites in the even-skipped stripe 3+7 enhancer. PLoS One (2014) 0.78
Associations of prodynorphin sequence variation with alcohol dependence and related traits are phenotype-specific and sex-dependent. Sci Rep (2015) 0.76
Comparative genetic approaches to the evolution of human brain and behavior. Am J Hum Biol (2010) 0.76
Genetic correlates of the evolving primate brain. Prog Brain Res (2012) 0.76
Genome-Wide Identification of Regulatory Sequences Undergoing Accelerated Evolution in the Human Genome. Mol Biol Evol (2016) 0.75
Human Lineage-Specific Transcriptional Regulation through GA-Binding Protein Transcription Factor Alpha (GABPa). Mol Biol Evol (2016) 0.75
The Mechanisms of Psychedelic Visionary Experiences: Hypotheses from Evolutionary Psychology. Front Neurosci (2017) 0.75
The human genome browser at UCSC. Genome Res (2002) 168.23
MODELTEST: testing the model of DNA substitution. Bioinformatics (1998) 101.19
Evolutionary trees from DNA sequences: a maximum likelihood approach. J Mol Evol (1981) 67.56
The hitch-hiking effect of a favourable gene. Genet Res (1974) 34.74
Genetic structure of human populations. Science (2002) 30.91
Whole-genome patterns of common DNA variation in three human populations. Science (2005) 21.22
Evolution at two levels in humans and chimpanzees. Science (1975) 21.07
A second-generation linkage map of the human genome. Nature (1992) 16.32
DnaSP version 3: an integrated program for molecular population genetics and molecular evolution analysis. Bioinformatics (1999) 14.86
Codon-substitution models for heterogeneous selection pressure at amino acid sites. Genetics (2000) 14.84
Hitchhiking under positive Darwinian selection. Genetics (2000) 14.72
A model of mutation appropriate to estimate the number of electrophoretically detectable alleles in a finite population. Genet Res (1973) 13.08
Genetic signatures of strong recent positive selection at the lactase gene. Am J Hum Genet (2004) 11.90
Distribution of gene frequency as a test of the theory of the selective neutrality of polymorphisms. Genetics (1973) 10.95
Inferring nonneutral evolution from human-chimp-mouse orthologous gene trios. Science (2003) 9.20
A scan for positively selected genes in the genomes of humans and chimpanzees. PLoS Biol (2005) 8.32
Intra- and interspecific variation in primate gene expression patterns. Science (2002) 7.92
Haplotype diversity and linkage disequilibrium at human G6PD: recent origin of alleles that confer malarial resistance. Science (2001) 7.87
The evolution of transcriptional regulation in eukaryotes. Mol Biol Evol (2003) 7.72
Molecular evolution of FOXP2, a gene involved in speech and language. Nature (2002) 5.89
Evolution at two levels: on genes and form. PLoS Biol (2005) 5.84
Elevated gene expression levels distinguish human from non-human primate brains. Proc Natl Acad Sci U S A (2003) 4.69
Abundant raw material for cis-regulatory evolution in humans. Mol Biol Evol (2002) 4.37
Salvinorin A: a potent naturally occurring nonnitrogenous kappa opioid selective agonist. Proc Natl Acad Sci U S A (2002) 4.34
Accelerated evolution of nervous system genes in the origin of Homo sapiens. Cell (2004) 4.24
DNA sequence and comparative analysis of chimpanzee chromosome 22. Nature (2004) 4.12
Enhanced partner preference in a promiscuous species by manipulating the expression of a single gene. Nature (2004) 4.00
Evolutionary developmental biology and the problem of variation. Evolution (2000) 3.99
Intrachromosomal gene conversion and the maintenance of sequence homogeneity among repeated genes. Genetics (1982) 3.70
DREAM is a Ca2+-regulated transcriptional repressor. Nature (1999) 3.54
Using genome scans of DNA polymorphism to infer adaptive population divergence. Mol Ecol (2005) 3.50
Lineage-specific gene duplication and loss in human and great ape evolution. PLoS Biol (2004) 3.45
Acupuncture and endorphins. Neurosci Lett (2004) 3.16
Abnormal cerebellar development and axonal decussation due to mutations in AHI1 in Joubert syndrome. Nat Genet (2004) 3.01
The probability of fixation in populations of changing size. Genetics (1997) 2.80
Deficit in attachment behavior in mice lacking the mu-opioid receptor gene. Science (2004) 2.76
Myosin gene mutation correlates with anatomical changes in the human lineage. Nature (2004) 2.69
Genome scans of DNA variability in humans reveal evidence for selective sweeps outside of Africa. Mol Biol Evol (2004) 2.64
Positive selection on a human-specific transcription factor binding site regulating IL4 expression. Curr Biol (2003) 2.59
Mixed-model reanalysis of primate data suggests tissue and species biases in oligonucleotide-based gene expression profiles. Genetics (2003) 2.50
A microsatellite variability screen for positive selection associated with the "out of Africa" habitat expansion of Drosophila melanogaster. Genetics (2003) 2.39
A genome scan to detect candidate regions influenced by local natural selection in human populations. Mol Biol Evol (2003) 2.30
A microsatellite-based multilocus screen for the identification of local selective sweeps. Genetics (2002) 2.27
Slow molecular clocks in Old World monkeys, apes, and humans. Mol Biol Evol (2002) 2.20
Low nucleotide diversity in chimpanzees and bonobos. Genetics (2003) 2.16
Inactivation of CMP-N-acetylneuraminic acid hydroxylase occurred prior to brain expansion during human evolution. Proc Natl Acad Sci U S A (2002) 2.00
Comparative analysis of gene-expression patterns in human and African great ape cultured fibroblasts. Genome Res (2003) 1.92
Radical alterations in the roles of homeobox genes during echinoderm evolution. Nature (1997) 1.86
Evolution of the human ASPM gene, a major determinant of brain size. Genetics (2003) 1.69
Functional analysis of human promoter polymorphisms. Hum Mol Genet (2003) 1.69
A functional polymorphism in the prodynorphin gene promotor is associated with temporal lobe epilepsy. Ann Neurol (2002) 1.65
DREAM is a critical transcriptional repressor for pain modulation. Cell (2002) 1.63
Molecular alterations in the neostriatum of human cocaine addicts. Synapse (1993) 1.62
From wild wolf to domestic dog: gene expression changes in the brain. Brain Res Mol Brain Res (2004) 1.59
On the divergence of alleles in nested subsamples from finite populations. Genetics (1986) 1.49
Reconstructing the evolutionary history of microcephalin, a gene controlling human brain size. Hum Mol Genet (2004) 1.46
Endogenous dynorphins inhibit excitatory neurotransmission and block LTP induction in the hippocampus. Nature (1993) 1.45
Human growth hormone 1 (GH1) gene expression: complex haplotype-dependent influence of polymorphic variation in the proximal promoter and locus control region. Hum Mutat (2003) 1.39
Comparing patterns of nucleotide substitution rates among chloroplast loci using the relative ratio test. Genetics (1997) 1.30
Population genetic and phylogenetic evidence for positive selection on regulatory mutations at the factor VII locus in humans. Genetics (2004) 1.25
Regulatory variation at glypican-3 underlies a major growth QTL in mice. PLoS Biol (2005) 1.18
A high proportion of polymorphisms in the promoters of brain expressed genes influences transcriptional activity. Biochim Biophys Acta (2004) 1.15
Human type I hair keratin pseudogene phihHaA has functional orthologs in the chimpanzee and gorilla: evidence for recent inactivation of the human gene after the Pan-Homo divergence. Hum Genet (2001) 1.15
An allelic variation in the human prodynorphin gene promoter alters stimulus-induced expression. J Neurochem (2000) 1.10
Clik1: a novel kinase targeted to actin stress fibers by the CLP-36 PDZ-LIM protein. J Cell Sci (2002) 1.06
Potentially functional polymorphism in the promoter region of prodynorphin gene may be associated with protection against cocaine dependence or abuse. Am J Med Genet (2002) 1.02
Positive selection in MAOA gene is human exclusive: determination of the putative amino acid change selected in the human lineage. Hum Genet (2004) 0.98
Selection and biased gene conversion in a multigene family: consequences of interallelic bias and threshold selection. Genetics (1986) 0.95
Functional analysis of the chimpanzee and human apo(a) promoter sequences: identification of sequence variations responsible for elevated transcriptional activity in chimpanzee. J Biol Chem (2001) 0.89
Functional analysis of human and chimpanzee promoters. Genome Biol (2005) 0.89
Subjects with major depression or bipolar disorder show reduction of prodynorphin mRNA expression in discrete nuclei of the amygdaloid complex. Mol Psychiatry (2002) 0.88
Epilepsy, CNS viral injury and dynorphin. Trends Pharmacol Sci (2004) 0.83
Allelic variation in the human prodynorphin gene promoter and schizophrenia. Neuropsychobiology (2002) 0.80
Finding the missing heritability of complex diseases. Nature (2009) 67.95
Integrating common and rare genetic variation in diverse human populations. Nature (2010) 32.30
Genome-wide association studies for complex traits: consensus, uncertainty and challenges. Nat Rev Genet (2008) 30.94
Biological, clinical and population relevance of 95 loci for blood lipids. Nature (2010) 28.21
Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearance. Nature (2009) 26.47
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. Nat Genet (2010) 23.08
Six new loci associated with body mass index highlight a neuronal influence on body weight regulation. Nat Genet (2008) 22.35
Large recurrent microdeletions associated with schizophrenia. Nature (2008) 20.25
Hundreds of variants clustered in genomic loci and biological pathways affect human height. Nature (2010) 20.01
Evolution of genes and genomes on the Drosophila phylogeny. Nature (2007) 18.01
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. Nat Genet (2010) 17.89
Genome-wide association analysis identifies 20 loci that influence adult height. Nat Genet (2008) 16.92
Evolutionary and biomedical insights from the rhesus macaque genome. Science (2007) 16.21
Common variants near MC4R are associated with fat mass, weight and risk of obesity. Nat Genet (2008) 15.94
A whole-genome association study of major determinants for host control of HIV-1. Science (2007) 15.19
Rare variants create synthetic genome-wide associations. PLoS Biol (2010) 14.43
Genetic variation in IL28B and spontaneous clearance of hepatitis C virus. Nature (2009) 13.99
Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease. Nat Genet (2011) 13.25
Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Nature (2011) 13.25
Genome-wide association study identifies eight loci associated with blood pressure. Nat Genet (2009) 12.44
Discovery of functional elements in 12 Drosophila genomes using evolutionary signatures. Nature (2007) 11.66
Variants in MTNR1B influence fasting glucose levels. Nat Genet (2008) 10.85
Common variants conferring risk of schizophrenia. Nature (2009) 10.37
Uncovering the roles of rare variants in common disease through whole-genome sequencing. Nat Rev Genet (2010) 9.53
Convergent adaptation of human lactase persistence in Africa and Europe. Nat Genet (2006) 9.44
Common genetic determinants of vitamin D insufficiency: a genome-wide association study. Lancet (2010) 8.89
Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution. Nat Genet (2010) 7.94
Discerning the ancestry of European Americans in genetic association studies. PLoS Genet (2007) 7.81
The evolution of transcriptional regulation in eukaryotes. Mol Biol Evol (2003) 7.72
De novo mutations in epileptic encephalopathies. Nature (2013) 7.42
WGAViewer: software for genomic annotation of whole genome association studies. Genome Res (2008) 7.15
Mapping cis- and trans-regulatory effects across multiple tissues in twins. Nat Genet (2012) 6.97
A genome-wide association study in chronic obstructive pulmonary disease (COPD): identification of two major susceptibility loci. PLoS Genet (2009) 6.93
Sequence variants at CHRNB3-CHRNA6 and CYP2A6 affect smoking behavior. Nat Genet (2010) 6.49
15q13.3 microdeletions increase risk of idiopathic generalized epilepsy. Nat Genet (2009) 6.21
Population genomics: whole-genome analysis of polymorphism and divergence in Drosophila simulans. PLoS Biol (2007) 6.18
The metabochip, a custom genotyping array for genetic studies of metabolic, cardiovascular, and anthropometric traits. PLoS Genet (2012) 6.15
Interleukin-28B polymorphism improves viral kinetics and is the strongest pretreatment predictor of sustained virologic response in genotype 1 hepatitis C virus. Gastroenterology (2010) 6.14
The architecture of gene regulatory variation across multiple human tissues: the MuTHER study. PLoS Genet (2011) 5.95
Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution. PLoS Genet (2009) 5.81
Genome-wide transcript profiles in aging and calorically restricted Drosophila melanogaster. Curr Biol (2002) 5.58
Genic intolerance to functional variation and the interpretation of personal genomes. PLoS Genet (2013) 5.58
Twenty bone-mineral-density loci identified by large-scale meta-analysis of genome-wide association studies. Nat Genet (2009) 5.32
Tissue-specific genetic control of splicing: implications for the study of complex traits. PLoS Biol (2008) 5.08
Genomic islands of speciation in Anopheles gambiae. PLoS Biol (2005) 5.03
A genome-wide investigation of SNPs and CNVs in schizophrenia. PLoS Genet (2009) 5.01
A genome-wide perspective of genetic variation in human metabolism. Nat Genet (2009) 5.00
ITPA gene variants protect against anaemia in patients treated for chronic hepatitis C. Nature (2010) 4.64
Selection and evaluation of tagging SNPs in the neuronal-sodium-channel gene SCN1A: implications for linkage-disequilibrium gene mapping. Am J Hum Genet (2003) 4.58
A mutation in VPS35, encoding a subunit of the retromer complex, causes late-onset Parkinson disease. Am J Hum Genet (2011) 4.52
Abundant raw material for cis-regulatory evolution in humans. Mol Biol Evol (2002) 4.37
A genome-wide association study confirms VKORC1, CYP2C9, and CYP4F2 as principal genetic determinants of warfarin dose. PLoS Genet (2009) 4.32
Whole-genome sequencing of a single proband together with linkage analysis identifies a Mendelian disease gene. PLoS Genet (2010) 4.29
Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium. Nat Genet (2009) 4.28
HLA-B*5701 genotype is a major determinant of drug-induced liver injury due to flucloxacillin. Nat Genet (2009) 4.11
Random drift and culture change. Proc Biol Sci (2004) 4.11
Genome-wide association study identifies five loci associated with lung function. Nat Genet (2009) 4.10
Recurrent microdeletions at 15q11.2 and 16p13.11 predispose to idiopathic generalized epilepsies. Brain (2009) 3.96
HLA-A*3101 and carbamazepine-induced hypersensitivity reactions in Europeans. N Engl J Med (2011) 3.93
The UK10K project identifies rare variants in health and disease. Nature (2015) 3.89
Comparative and demographic analysis of orang-utan genomes. Nature (2011) 3.83
Promoter regions of many neural- and nutrition-related genes have experienced positive selection during human evolution. Nat Genet (2007) 3.77
Genetic loci influencing kidney function and chronic kidney disease. Nat Genet (2010) 3.75
Comparative genomics of centrality and essentiality in three eukaryotic protein-interaction networks. Mol Biol Evol (2004) 3.73
The characterization of twenty sequenced human genomes. PLoS Genet (2010) 3.72
Common genetic variation and the control of HIV-1 in humans. PLoS Genet (2009) 3.68
Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels. Circulation (2011) 3.68
IL28B genotype is associated with differential expression of intrahepatic interferon-stimulated genes in patients with chronic hepatitis C. Hepatology (2010) 3.57
Genetic structure of Europeans: a view from the North-East. PLoS One (2009) 3.46
Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure. Nat Genet (2011) 3.40
Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies. Nat Genet (2010) 3.37
Association of multidrug resistance in epilepsy with a polymorphism in the drug-transporter gene ABCB1. N Engl J Med (2003) 3.37
Clinical application of exome sequencing in undiagnosed genetic conditions. J Med Genet (2012) 3.33
Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture. Nat Genet (2013) 3.25
BLUEPRINT to decode the epigenetic signature written in blood. Nat Biotechnol (2012) 3.24
Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals. PLoS Genet (2012) 3.21
Identification of an imprinted master trans regulator at the KLF14 locus related to multiple metabolic phenotypes. Nat Genet (2011) 3.20
New gene functions in megakaryopoiesis and platelet formation. Nature (2011) 3.14
Long-range LD can confound genome scans in admixed populations. Am J Hum Genet (2008) 3.06
The evolution of mammalian gene families. PLoS One (2006) 3.04
Genome-wide association analyses identify 18 new loci associated with serum urate concentrations. Nat Genet (2012) 3.04
CAFE: a computational tool for the study of gene family evolution. Bioinformatics (2006) 3.02
Hepatitis C pharmacogenetics: state of the art in 2010. Hepatology (2011) 2.99
Common variants near TERC are associated with mean telomere length. Nat Genet (2010) 2.98
Disentangling the effects of demography and selection in human history. Mol Biol Evol (2004) 2.97
Host determinants of HIV-1 control in African Americans. J Infect Dis (2010) 2.90
Multicentre search for genetic susceptibility loci in sporadic epilepsy syndrome and seizure types: a case-control study. Lancet Neurol (2007) 2.88
An IL28B polymorphism determines treatment response of hepatitis C virus genotype 2 or 3 patients who do not achieve a rapid virologic response. Gastroenterology (2010) 2.87
Does evolutionary theory need a rethink? Nature (2014) 2.82
Collaborative meta-analysis: associations of 150 candidate genes with osteoporosis and osteoporotic fracture. Ann Intern Med (2009) 2.80
Novel associations of multiple genetic loci with plasma levels of factor VII, factor VIII, and von Willebrand factor: The CHARGE (Cohorts for Heart and Aging Research in Genome Epidemiology) Consortium. Circulation (2010) 2.78
A polymorphism near IL28B is associated with spontaneous clearance of acute hepatitis C virus and jaundice. Gastroenterology (2010) 2.78
Seventy-five genetic loci influencing the human red blood cell. Nature (2012) 2.77
Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile. Nat Genet (2011) 2.73
Priorities and standards in pharmacogenetic research. Nat Genet (2005) 2.65
Genome-wide association study identifies variants at 9p21 and 22q13 associated with development of cutaneous nevi. Nat Genet (2009) 2.65
Testing the ortholog conjecture with comparative functional genomic data from mammals. PLoS Comput Biol (2011) 2.63
Rare deletions at 16p13.11 predispose to a diverse spectrum of sporadic epilepsy syndromes. Am J Hum Genet (2010) 2.61
Positive selection on a human-specific transcription factor binding site regulating IL4 expression. Curr Biol (2003) 2.59