Published in J Cell Sci on January 01, 2008
Non-muscle myosin II takes centre stage in cell adhesion and migration. Nat Rev Mol Cell Biol (2009) 7.77
Myosin II isoforms identify distinct functional modules that support integrity of the epithelial zonula adherens. Nat Cell Biol (2010) 2.51
Inhibition of "self" engulfment through deactivation of myosin-II at the phagocytic synapse between human cells. J Cell Biol (2008) 2.39
The role of myosin II in glioma invasion of the brain. Mol Biol Cell (2008) 2.20
T cell antigen receptor signaling and immunological synapse stability require myosin IIA. Nat Immunol (2009) 2.17
Cytoskeletal coherence requires myosin-IIA contractility. J Cell Sci (2010) 2.13
Rab and actomyosin-dependent fission of transport vesicles at the Golgi complex. Nat Cell Biol (2010) 1.94
Local cortical tension by myosin II guides 3D endothelial cell branching. Curr Biol (2009) 1.85
A mechanical model of actin stress fiber formation and substrate elasticity sensing in adherent cells. Proc Natl Acad Sci U S A (2010) 1.77
Role for the actomyosin complex in regulated exocytosis revealed by intravital microscopy. Proc Natl Acad Sci U S A (2011) 1.74
Chronic lymphocytic leukemia antibodies with a common stereotypic rearrangement recognize nonmuscle myosin heavy chain IIA. Blood (2008) 1.67
Blood vessel tubulogenesis requires Rasip1 regulation of GTPase signaling. Dev Cell (2011) 1.55
Force generated by actomyosin contraction builds bridges between adhesive contacts. EMBO J (2010) 1.47
Multiple regulatory steps control mammalian nonmuscle myosin II assembly in live cells. Mol Biol Cell (2008) 1.45
Pak1 regulates branching morphogenesis in 3D MDCK cell culture by a PIX and beta1-integrin-dependent mechanism. Am J Physiol Cell Physiol (2010) 1.44
Mouse models of MYH9-related disease: mutations in nonmuscle myosin II-A. Blood (2011) 1.41
Flotillin microdomains interact with the cortical cytoskeleton to control uropod formation and neutrophil recruitment. J Cell Biol (2010) 1.40
The C-terminal tail region of nonmuscle myosin II directs isoform-specific distribution in migrating cells. Mol Biol Cell (2008) 1.38
Isoform-specific contributions of alpha-actinin to glioma cell mechanobiology. PLoS One (2009) 1.34
Force propagation across cells: mechanical coherence of dynamic cytoskeletons. Curr Opin Cell Biol (2009) 1.31
Nonmuscle myosin II exerts tension but does not translocate actin in vertebrate cytokinesis. Proc Natl Acad Sci U S A (2012) 1.29
NMII forms a contractile transcellular sarcomeric network to regulate apical cell junctions and tissue geometry. Curr Biol (2013) 1.29
Actin and myosin contribute to mammalian mitochondrial DNA maintenance. Nucleic Acids Res (2011) 1.27
Mechanical control of tissue morphogenesis. Circ Res (2008) 1.20
Myosin II regulates extension, growth and patterning in the mammalian cochlear duct. Development (2009) 1.19
Vascular smooth muscle phenotypic diversity and function. Physiol Genomics (2010) 1.18
MYBPH, a transcriptional target of TTF-1, inhibits ROCK1, and reduces cell motility and metastasis. EMBO J (2011) 1.17
Non-muscle myosin II regulates survival threshold of pluripotent stem cells. Nat Commun (2010) 1.16
Myosin II has distinct functions in PNS and CNS myelin sheath formation. J Cell Biol (2008) 1.14
Myosin II directly binds and inhibits Dbl family guanine nucleotide exchange factors: a possible link to Rho family GTPases. J Cell Biol (2010) 1.13
Nonmuscle myosin is regulated during smooth muscle contraction. Am J Physiol Heart Circ Physiol (2009) 1.13
Podocyte-specific deletion of Myh9 encoding nonmuscle myosin heavy chain 2A predisposes mice to glomerulopathy. Mol Cell Biol (2011) 1.11
Protein kinase C activation disrupts epithelial apical junctions via ROCK-II dependent stimulation of actomyosin contractility. BMC Cell Biol (2009) 1.11
Distinct functions for Rho1 in maintaining adherens junctions and apical tension in remodeling epithelia. J Cell Biol (2009) 1.10
Kif26b, a kinesin family gene, regulates adhesion of the embryonic kidney mesenchyme. Proc Natl Acad Sci U S A (2010) 1.09
Myosin IIA dependent retrograde flow drives 3D cell migration. Biophys J (2010) 1.09
Myosin-interacting guanine exchange factor (MyoGEF) regulates the invasion activity of MDA-MB-231 breast cancer cells through activation of RhoA and RhoC. Oncogene (2009) 1.07
Nonmuscle myosin II is responsible for maintaining endothelial cell basal tone and stress fiber integrity. Am J Physiol Cell Physiol (2008) 1.07
Myosin II tailpiece determines its paracrystal structure, filament assembly properties, and cellular localization. J Biol Chem (2009) 1.07
Blebbistatin stabilizes the helical order of myosin filaments by promoting the switch 2 closed state. Biophys J (2008) 1.06
Cross-correlated TIRF/AFM reveals asymmetric distribution of force-generating heads along self-assembled, "synthetic" myosin filaments. Biophys J (2009) 1.05
Dependence of myoblast fusion on a cortical actin wall and nonmuscle myosin IIA. Dev Biol (2008) 1.04
Non-muscle myosin IIB is critical for nuclear translocation during 3D invasion. J Cell Biol (2015) 1.04
Conditional ablation of nonmuscle myosin II-B delineates heart defects in adult mice. Circ Res (2009) 1.03
Kinetic characterization of nonmuscle myosin IIb at the single molecule level. J Biol Chem (2012) 1.02
Myosin-II negatively regulates minor process extension and the temporal development of neuronal polarity. Dev Neurobiol (2009) 1.02
Left-right symmetry breaking in tissue morphogenesis via cytoskeletal mechanics. Circ Res (2012) 1.02
The LIM domain of zyxin is sufficient for force-induced accumulation of zyxin during cell migration. Biophys J (2011) 1.01
Cdc42 antagonizes Rho1 activity at adherens junctions to limit epithelial cell apical tension. J Cell Biol (2009) 0.99
Signaling through myosin light chain kinase in smooth muscles. J Biol Chem (2013) 0.98
Quantitative apical membrane proteomics reveals vasopressin-induced actin dynamics in collecting duct cells. Proc Natl Acad Sci U S A (2013) 0.98
How a cell crawls and the role of cortical myosin II. Eukaryot Cell (2009) 0.98
An alternatively spliced isoform of non-muscle myosin II-C is not regulated by myosin light chain phosphorylation. J Biol Chem (2009) 0.97
Myosin II motor proteins with different functions determine the fate of lamellipodia extension during cell spreading. PLoS One (2010) 0.97
PTK7 regulates myosin II activity to orient planar polarity in the mammalian auditory epithelium. Curr Biol (2012) 0.96
The tumor suppressor Lgl1 regulates NMII-A cellular distribution and focal adhesion morphology to optimize cell migration. Mol Biol Cell (2012) 0.94
Myosin II is a negative regulator of oligodendrocyte morphological differentiation. J Neurosci Res (2012) 0.93
Smooth muscle myosin light chain kinase efficiently phosphorylates serine 15 of cardiac myosin regulatory light chain. Biochem Biophys Res Commun (2011) 0.93
A proteomic study of myosin II motor proteins during tumor cell migration. J Mol Biol (2011) 0.93
N-methyl-D-aspartate receptor subunits are non-myosin targets of myosin regulatory light chain. J Biol Chem (2008) 0.93
Rac1-dependent phosphorylation and focal adhesion recruitment of myosin IIA regulates migration and mechanosensing. Curr Biol (2014) 0.92
Potential roles of myosin VI in cell motility. Biochem Soc Trans (2009) 0.92
Nephron progenitors in the metanephric mesenchyme. Pediatr Nephrol (2011) 0.91
Polarity and cell fate specification in the control of Caenorhabditis elegans gastrulation. Dev Dyn (2009) 0.91
Actin in herpesvirus infection. Viruses (2011) 0.90
Myosin IIA deficient cells migrate efficiently despite reduced traction forces at cell periphery. Biol Open (2013) 0.89
Non-muscle myosin IIA transports a Golgi glycosyltransferase to the endoplasmic reticulum by binding to its cytoplasmic tail. Int J Biochem Cell Biol (2012) 0.89
Distinct tissue distributions and subcellular localizations of differently phosphorylated forms of the myosin regulatory light chain in Drosophila. Gene Expr Patterns (2010) 0.89
Myosin IIB isoform plays an essential role in the formation of two distinct types of macropinosomes. Cytoskeleton (Hoboken) (2010) 0.89
Phosphatidylinositol 3'-kinase signalling supports cell height in established epithelial monolayers. J Mol Histol (2010) 0.88
Myosin motor proteins are involved in the final stages of the secretory pathways. Biochem Soc Trans (2011) 0.88
Distinct functional effects for dynamin 3 during megakaryocytopoiesis. Stem Cells Dev (2011) 0.88
LPA(1) -induced migration requires nonmuscle myosin II light chain phosphorylation in breast cancer cells. J Cell Physiol (2011) 0.88
A novel interaction of CLN3 with nonmuscle myosin-IIB and defects in cell motility of Cln3(-/-) cells. Exp Cell Res (2010) 0.88
Background strain and the differential susceptibility of podocyte-specific deletion of Myh9 on murine models of experimental glomerulosclerosis and HIV nephropathy. PLoS One (2013) 0.85
Convergence and extrusion are required for normal fusion of the mammalian secondary palate. PLoS Biol (2015) 0.84
Altered hemodynamics, endothelial function, and protein expression occur with aortic coarctation and persist after repair. Am J Physiol Heart Circ Physiol (2012) 0.84
A human de novo mutation in MYH10 phenocopies the loss of function mutation in mice. Rare Dis (2013) 0.84
HLA class I-mediated stress fiber formation requires ERK1/2 activation in the absence of an increase in intracellular Ca2+ in human aortic endothelial cells. Am J Physiol Cell Physiol (2012) 0.84
Myosin light chain kinases and phosphatase in mitosis and cytokinesis. Arch Biochem Biophys (2011) 0.83
A non-enzymatic function of Golgi glycosyltransferases: mediation of Golgi fragmentation by interaction with non-muscle myosin IIA. Glycobiology (2013) 0.83
Reduced FOXO1 expression accelerates skin wound healing and attenuates scarring. Am J Pathol (2014) 0.83
The Abl and Arg non-receptor tyrosine kinases regulate different zones of stress fiber, focal adhesion, and contractile network localization in spreading fibroblasts. Cytoskeleton (Hoboken) (2010) 0.83
Independent specialisation of myosin II paralogues in muscle vs. non-muscle functions during early animal evolution: a ctenophore perspective. BMC Evol Biol (2012) 0.83
Enterohemorrhagic Escherichia coli infection stimulates Shiga toxin 1 macropinocytosis and transcytosis across intestinal epithelial cells. Am J Physiol Cell Physiol (2011) 0.83
INSIGHTS INTO THE ROLES OF NON-MUSCLE MYOSIN IIA IN HUMAN KERATINOCYTE MIGRATION. Cell Mol Bioeng (2009) 0.82
The positively charged region of the myosin IIC non-helical tailpiece promotes filament assembly. J Biol Chem (2009) 0.82
Tensions divide. Nat Cell Biol (2010) 0.82
Patterns of periodic holes created by increased cell motility. Interface Focus (2012) 0.82
Role of nonmuscle myosin IIB and N-RAP in cell spreading and myofibril assembly in primary mouse cardiomyocytes. Cell Motil Cytoskeleton (2008) 0.81
In vivo studies on nonmuscle myosin II expression and function in heart development. Front Biosci (Landmark Ed) (2012) 0.81
Homoharringtonine binds to and increases myosin-9 in myeloid leukaemia. Br J Pharmacol (2015) 0.81
Novel regulation and dynamics of myosin II activation during epidermal wound responses. Exp Cell Res (2010) 0.81
Role of LARP6 and nonmuscle myosin in partitioning of collagen mRNAs to the ER membrane. PLoS One (2014) 0.81
Clinicopathological significance of NMIIA overexpression in human gastric cancer. Int J Mol Sci (2012) 0.80
Angiotensin-II mediates nonmuscle myosin II activation and expression and contributes to human keloid disease progression. Mol Med (2011) 0.80
Constitutive phosphorylation of myosin phosphatase targeting subunit-1 in smooth muscle. J Physiol (2014) 0.80
Differential Contributions of Nonmuscle Myosin II Isoforms and Functional Domains to Stress Fiber Mechanics. Sci Rep (2015) 0.80
Ultraslow myosin molecular motors of placental contractile stem villi in humans. PLoS One (2014) 0.79
Non-muscle myosin II takes centre stage in cell adhesion and migration. Nat Rev Mol Cell Biol (2009) 7.77
Myosin IIA regulates cell motility and actomyosin-microtubule crosstalk. Nat Cell Biol (2007) 4.26
Defects in cell adhesion and the visceral endoderm following ablation of nonmuscle myosin heavy chain II-A in mice. J Biol Chem (2004) 3.31
Nonmuscle myosin IIb is involved in the guidance of fibroblast migration. Mol Biol Cell (2003) 3.02
Identification and characterization of nonmuscle myosin II-C, a new member of the myosin II family. J Biol Chem (2003) 2.98
Myosin II isoforms identify distinct functional modules that support integrity of the epithelial zonula adherens. Nat Cell Biol (2010) 2.51
Basic mechanism of three-dimensional collagen fibre transport by fibroblasts. Nat Cell Biol (2005) 2.28
Identification of neuronal nuclei (NeuN) as Fox-3, a new member of the Fox-1 gene family of splicing factors. J Biol Chem (2009) 2.16
Disease-associated mutations and alternative splicing alter the enzymatic and motile activity of nonmuscle myosins II-B and II-C. J Biol Chem (2005) 1.86
Local cortical tension by myosin II guides 3D endothelial cell branching. Curr Biol (2009) 1.85
Confinement-optimized three-dimensional T cell amoeboid motility is modulated via myosin IIA-regulated adhesions. Nat Immunol (2010) 1.82
Vertebrate nonmuscle myosin II isoforms rescue small interfering RNA-induced defects in COS-7 cell cytokinesis. J Biol Chem (2005) 1.77
A point mutation in the motor domain of nonmuscle myosin II-B impairs migration of distinct groups of neurons. Mol Biol Cell (2004) 1.73
A unique role for nonmuscle myosin heavy chain IIA in regulation of epithelial apical junctions. PLoS One (2007) 1.72
The May-Hegglin anomaly gene MYH9 is a negative regulator of platelet biogenesis modulated by the Rho-ROCK pathway. Blood (2007) 1.64
Loss of cell adhesion causes hydrocephalus in nonmuscle myosin II-B-ablated and mutated mice. Mol Biol Cell (2007) 1.49
Replacement of nonmuscle myosin II-B with II-A rescues brain but not cardiac defects in mice. J Biol Chem (2007) 1.48
Mouse models of MYH9-related disease: mutations in nonmuscle myosin II-A. Blood (2011) 1.41
Ablation and mutation of nonmuscle myosin heavy chain II-B results in a defect in cardiac myocyte cytokinesis. Circ Res (2003) 1.40
Ablation of nonmuscle myosin II-B and II-C reveals a role for nonmuscle myosin II in cardiac myocyte karyokinesis. Mol Biol Cell (2010) 1.36
Nonmuscle myosin II exerts tension but does not translocate actin in vertebrate cytokinesis. Proc Natl Acad Sci U S A (2012) 1.29
NMII forms a contractile transcellular sarcomeric network to regulate apical cell junctions and tissue geometry. Curr Biol (2013) 1.29
Micro-environmental control of cell migration--myosin IIA is required for efficient migration in fibrillar environments through control of cell adhesion dynamics. J Cell Sci (2012) 1.26
Characterization of three full-length human nonmuscle myosin II paralogs. J Biol Chem (2013) 1.23
Fox-3 and PSF interact to activate neural cell-specific alternative splicing. Nucleic Acids Res (2010) 1.22
Myosin II regulates extension, growth and patterning in the mammalian cochlear duct. Development (2009) 1.19
Nonmuscle myosin II isoform and domain specificity during early mouse development. Proc Natl Acad Sci U S A (2010) 1.16
Non-muscle myosin II regulates survival threshold of pluripotent stem cells. Nat Commun (2010) 1.16
Distinct and redundant roles of the non-muscle myosin II isoforms and functional domains. Biochem Soc Trans (2011) 1.15
A specific isoform of nonmuscle myosin II-C is required for cytokinesis in a tumor cell line. J Biol Chem (2006) 1.14
Non-muscle myosin IIA differentially regulates intestinal epithelial cell restitution and matrix invasion. Am J Pathol (2009) 1.09
A novel guanine nucleotide exchange factor MyoGEF is required for cytokinesis. Cell Cycle (2006) 1.07
Menin, a tumor suppressor, associates with nonmuscle myosin II-A heavy chain. Oncogene (2003) 1.06
Induction of nonmuscle myosin heavy chain II-C by butyrate in RAW 264.7 mouse macrophages. J Biol Chem (2003) 1.05
Conditional ablation of nonmuscle myosin II-B delineates heart defects in adult mice. Circ Res (2009) 1.03
Function of the neuron-specific alternatively spliced isoforms of nonmuscle myosin II-B during mouse brain development. Mol Biol Cell (2006) 1.02
Pitx2a expression alters actin-myosin cytoskeleton and migration of HeLa cells through Rho GTPase signaling. Mol Biol Cell (2002) 1.01
An alternatively spliced isoform of non-muscle myosin II-C is not regulated by myosin light chain phosphorylation. J Biol Chem (2009) 0.97
Nonmuscle myosin IIB links cytoskeleton to IRE1α signaling during ER stress. Dev Cell (2012) 0.92
The B2 alternatively spliced isoform of nonmuscle myosin II-B lacks actin-activated MgATPase activity and in vitro motility. Biochem Biophys Res Commun (2007) 0.89
LPA(1) -induced migration requires nonmuscle myosin II light chain phosphorylation in breast cancer cells. J Cell Physiol (2011) 0.88
Nonmuscle myosin II is required for internalization of the epidermal growth factor receptor and modulation of downstream signaling. J Biol Chem (2012) 0.87
N-cadherin sustains motility and polarity of future cortical interneurons during tangential migration. J Neurosci (2013) 0.84
Rap1 activation in collagen phagocytosis is dependent on nonmuscle myosin II-A. Mol Biol Cell (2008) 0.83
In vivo studies on nonmuscle myosin II expression and function in heart development. Front Biosci (Landmark Ed) (2012) 0.81
Nonmuscle myosin II is a critical regulator of clathrin-mediated endocytosis. Traffic (2014) 0.81
Non-muscle myosin IIB is essential for cytokinesis during male meiotic cell divisions. Dev Biol (2012) 0.79
Keratin 5-Cre-driven excision of nonmuscle myosin IIA in early embryo trophectoderm leads to placenta defects and embryonic lethality. Dev Biol (2013) 0.77
Corrigendum: Cell migration and antigen capture are antagonistic processes coupled by myosin II in dendritic cells. Nat Commun (2015) 0.75