Published in Curr Biol on January 29, 2009
Collective cell migration in morphogenesis, regeneration and cancer. Nat Rev Mol Cell Biol (2009) 9.87
Random versus directionally persistent cell migration. Nat Rev Mol Cell Biol (2009) 4.99
Mechanical control of tissue and organ development. Development (2010) 3.18
Vinculin associates with endothelial VE-cadherin junctions to control force-dependent remodeling. J Cell Biol (2012) 2.12
Resolution doubling in live, multicellular organisms via multifocal structured illumination microscopy. Nat Methods (2012) 2.00
Spatially isotropic four-dimensional imaging with dual-view plane illumination microscopy. Nat Biotechnol (2013) 1.92
Mechanical signaling through the cytoskeleton regulates cell proliferation by coordinated focal adhesion and Rho GTPase signaling. J Cell Sci (2011) 1.90
In situ force mapping of mammary gland transformation. Integr Biol (Camb) (2011) 1.78
Visualizing extravasation dynamics of metastatic tumor cells. J Cell Sci (2010) 1.67
Crawling from soft to stiff matrix polarizes the cytoskeleton and phosphoregulates myosin-II heavy chain. J Cell Biol (2012) 1.65
Mechanics of the F-actin cytoskeleton. J Biomech (2009) 1.58
Comparative mechanisms of cancer cell migration through 3D matrix and physiological microtracks. Am J Physiol Cell Physiol (2014) 1.50
Filamin A-beta1 integrin complex tunes epithelial cell response to matrix tension. Mol Biol Cell (2009) 1.47
FMN2 Makes Perinuclear Actin to Protect Nuclei during Confined Migration and Promote Metastasis. Cell (2016) 1.46
Identification of a mechanochemical checkpoint and negative feedback loop regulating branching morphogenesis. Dev Biol (2009) 1.41
Myosin IIA/IIB restrict adhesive and protrusive signaling to generate front-back polarity in migrating cells. J Cell Biol (2011) 1.36
The role of the cytoskeleton in cellular force generation in 2D and 3D environments. Phys Biol (2011) 1.32
Endogenous patterns of mechanical stress are required for branching morphogenesis. Integr Biol (Camb) (2010) 1.31
Differential remodeling of actin cytoskeleton architecture by profilin isoforms leads to distinct effects on cell migration and invasion. Cancer Cell (2012) 1.26
Distinct ECM mechanosensing pathways regulate microtubule dynamics to control endothelial cell branching morphogenesis. J Cell Biol (2011) 1.24
Engineering strategies to recapitulate epithelial morphogenesis within synthetic three-dimensional extracellular matrix with tunable mechanical properties. Phys Biol (2011) 1.07
Paxillin mediates sensing of physical cues and regulates directional cell motility by controlling lamellipodia positioning. PLoS One (2011) 1.06
Non-muscle myosin IIB is critical for nuclear translocation during 3D invasion. J Cell Biol (2015) 1.04
Nogo-A is a negative regulator of CNS angiogenesis. Proc Natl Acad Sci U S A (2013) 1.02
Actin stress fibre subtypes in mesenchymal-migrating cells. Open Biol (2013) 0.99
Global and local regulation of clathrin-coated pit dynamics detected on patterned substrates. Biophys J (2009) 0.99
Stiffness-controlled three-dimensional extracellular matrices for high-resolution imaging of cell behavior. Nat Protoc (2012) 0.99
Matrix microarchitecture and myosin II determine adhesion in 3D matrices. Curr Biol (2013) 0.98
Myosin II controls cellular branching morphogenesis and migration in three dimensions by minimizing cell-surface curvature. Nat Cell Biol (2015) 0.97
Shroom2 regulates contractility to control endothelial morphogenesis. Mol Biol Cell (2011) 0.95
Local and global dynamics of the basement membrane during branching morphogenesis require protease activity and actomyosin contractility. Dev Biol (2014) 0.95
Mechanobiology of tumor invasion: engineering meets oncology. Crit Rev Oncol Hematol (2011) 0.94
Myosin II is a negative regulator of oligodendrocyte morphological differentiation. J Neurosci Res (2012) 0.93
The role of extracellular matrix in vascular branching morphogenesis. Cell Adh Migr (2012) 0.93
Angiogenic sprouting requires the fine tuning of endothelial cell cohesion by the Raf-1/Rok-α complex. Dev Cell (2011) 0.90
Rac1 and Aurora A regulate MCAK to polarize microtubule growth in migrating endothelial cells. J Cell Biol (2014) 0.89
Incoherent structured illumination improves optical sectioning and contrast in multiphoton super-resolution microscopy. Opt Express (2015) 0.87
Myelinating glia differentiation is regulated by extracellular matrix elasticity. Sci Rep (2016) 0.86
Non-muscle myosins in tumor progression, cancer cell invasion, and metastasis. Cytoskeleton (Hoboken) (2014) 0.85
The development of a novel high throughput computational tool for studying individual and collective cellular migration. PLoS One (2013) 0.85
Vinculin is required for cell polarization, migration, and extracellular matrix remodeling in 3D collagen. FASEB J (2015) 0.84
Laminin-3B11, a novel vascular-type laminin capable of inducing prominent lamellipodial protrusions in microvascular endothelial cells. J Biol Chem (2010) 0.83
To pull or be pulled: parsing the multiple modes of mechanotransduction. Curr Opin Cell Biol (2013) 0.82
Rho Kinase Regulation of Fibroblast Migratory Mechanics in Fibrillar Collagen Matrices. Cell Mol Bioeng (2010) 0.82
Structure of a highly conserved domain of Rock1 required for Shroom-mediated regulation of cell morphology. PLoS One (2013) 0.81
Quantification of local matrix deformations and mechanical properties during capillary morphogenesis in 3D. Integr Biol (Camb) (2012) 0.81
Microtubule dynamics regulation contributes to endothelial morphogenesis. Bioarchitecture (2012) 0.80
Non-muscle myosin II regulates neuronal actin dynamics by interacting with guanine nucleotide exchange factors. PLoS One (2014) 0.78
Nonmuscle myosin II regulation of lung epithelial morphology. Dev Dyn (2012) 0.78
Patterned cell and matrix dynamics in branching morphogenesis. J Cell Biol (2017) 0.78
Matrix rigidity regulates the microtubule network polarization in migration. Cytoskeleton (Hoboken) (2016) 0.76
Cancer cell motility: lessons from migration in confined spaces. Nat Rev Cancer (2016) 0.76
Non-muscle myosin II in disease: mechanisms and therapeutic opportunities. Dis Model Mech (2015) 0.76
Engineered Models of Confined Cell Migration. Annu Rev Biomed Eng (2016) 0.76
Three-dimensional collagen matrix induces a mechanosensitive invasive epithelial phenotype. Sci Rep (2017) 0.75
High-resolution Time-lapse Imaging and Automated Analysis of Microtubule Dynamics in Living Human Umbilical Vein Endothelial Cells. J Vis Exp (2016) 0.75
Perturbation of invadolysin disrupts cell migration in zebrafish (Danio rerio). Exp Cell Res (2013) 0.75
Three-Dimensional Characterization of Mechanical Interactions between Endothelial Cells and Extracellular Matrix during Angiogenic Sprouting. Sci Rep (2016) 0.75
Engineering therapies in the CNS: what works and what can be translated. Neurosci Lett (2012) 0.75
MCAK-mediated regulation of endothelial cell microtubule dynamics is mechanosensitive to myosin-II contractility. Mol Biol Cell (2017) 0.75
Adaptive optics improves multiphoton super-resolution imaging. Nat Methods (2017) 0.75
Mechanical forces direct stem cell behaviour in development and regeneration. Nat Rev Mol Cell Biol (2017) 0.75
Tissue cells feel and respond to the stiffness of their substrate. Science (2005) 23.42
Mechanisms of angiogenesis and arteriogenesis. Nat Med (2000) 13.88
VEGF guides angiogenic sprouting utilizing endothelial tip cell filopodia. J Cell Biol (2003) 12.96
In vivo imaging of embryonic vascular development using transgenic zebrafish. Dev Biol (2002) 11.62
Notch signalling limits angiogenic cell behaviour in developing zebrafish arteries. Nature (2007) 4.65
Prespecification and plasticity: shifting mechanisms of cell migration. Curr Opin Cell Biol (2004) 3.78
Cell migration in 3D matrix. Curr Opin Cell Biol (2005) 3.63
Myosin II filament assemblies in the active lamella of fibroblasts: their morphogenesis and role in the formation of actin filament bundles. J Cell Biol (1995) 3.55
Nonmuscle myosin II moves in new directions. J Cell Sci (2008) 3.39
Nonmuscle myosin IIb is involved in the guidance of fibroblast migration. Mol Biol Cell (2003) 3.02
Mechanical signaling and the cellular response to extracellular matrix in angiogenesis and cardiovascular physiology. Circ Res (2002) 2.96
ERK-MAPK signaling opposes Rho-kinase to promote endothelial cell survival and sprouting during angiogenesis. Cancer Cell (2006) 2.20
Responses of fibroblasts to anchorage of dorsal extracellular matrix receptors. Proc Natl Acad Sci U S A (2004) 2.18
Myosin II and mechanotransduction: a balancing act. Trends Cell Biol (2007) 1.85
Matrix metalloproteinases (MMPs) regulate fibrin-invasive activity via MT1-MMP-dependent and -independent processes. J Exp Med (2002) 1.81
RhoA-kinase and myosin II are required for the maintenance of growth cone polarity and guidance by nerve growth factor. J Neurobiol (2006) 1.79
Traction forces of fibroblasts are regulated by the Rho-dependent kinase but not by the myosin light chain kinase. Arch Biochem Biophys (2006) 1.76
Angiogenesis: vascular remodeling of the extracellular matrix involves metalloproteinases. Curr Opin Hematol (2003) 1.71
Inhibition of rho-kinase-induced myristoylated alanine-rich C kinase substrate (MARCKS) phosphorylation in human neuronal cells by H-1152, a novel and specific Rho-kinase inhibitor. J Neurochem (2002) 1.69
Agent-based simulation of notch-mediated tip cell selection in angiogenic sprout initialisation. J Theor Biol (2007) 1.60
Cellular responses to substrate topography: role of myosin II and focal adhesion kinase. Biophys J (2006) 1.58
The effects of matrix stiffness and RhoA on the phenotypic plasticity of smooth muscle cells in a 3-D biosynthetic hydrogel system. Biomaterials (2008) 1.51
How do endothelial cells orientate? EXS (2005) 1.32
Mechanical strain regulates endothelial cell patterning in vitro. Tissue Eng (2007) 1.26
Rho signaling and mechanical control of vascular development. Curr Opin Hematol (2008) 1.17
Myosin IIA is required for neurite outgrowth inhibition produced by repulsive guidance molecule. J Neurochem (2007) 1.06
Contraction reaction: mechanical regulation of Rho GTPase. Trends Cell Biol (2004) 0.98
Asymmetry in the distribution of free versus cytoskeletal myosin II in locomoting microcapillary endothelial cells. Exp Cell Res (1997) 0.92
Non-muscle myosin II takes centre stage in cell adhesion and migration. Nat Rev Mol Cell Biol (2009) 7.77
Nanoscale architecture of integrin-based cell adhesions. Nature (2010) 5.88
Interferometric fluorescent super-resolution microscopy resolves 3D cellular ultrastructure. Proc Natl Acad Sci U S A (2009) 5.31
Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation. Nat Cell Biol (2011) 4.59
Myosin IIA regulates cell motility and actomyosin-microtubule crosstalk. Nat Cell Biol (2007) 4.26
Mechanical integration of actin and adhesion dynamics in cell migration. Annu Rev Cell Dev Biol (2010) 4.06
High resolution traction force microscopy based on experimental and computational advances. Biophys J (2007) 3.89
Myosin II activity regulates vinculin recruitment to focal adhesions through FAK-mediated paxillin phosphorylation. J Cell Biol (2010) 3.56
Traction stress in focal adhesions correlates biphasically with actin retrograde flow speed. J Cell Biol (2008) 3.44
Nonmuscle myosin II moves in new directions. J Cell Sci (2008) 3.39
Defects in cell adhesion and the visceral endoderm following ablation of nonmuscle myosin heavy chain II-A in mice. J Biol Chem (2004) 3.31
Nonmuscle myosin IIb is involved in the guidance of fibroblast migration. Mol Biol Cell (2003) 3.02
Identification and characterization of nonmuscle myosin II-C, a new member of the myosin II family. J Biol Chem (2003) 2.98
Force fluctuations within focal adhesions mediate ECM-rigidity sensing to guide directed cell migration. Cell (2012) 2.87
Myosin II isoforms identify distinct functional modules that support integrity of the epithelial zonula adherens. Nat Cell Biol (2010) 2.51
PyK2 and FAK connections to p190Rho guanine nucleotide exchange factor regulate RhoA activity, focal adhesion formation, and cell motility. J Cell Biol (2008) 2.31
Basic mechanism of three-dimensional collagen fibre transport by fibroblasts. Nat Cell Biol (2005) 2.28
Identification of neuronal nuclei (NeuN) as Fox-3, a new member of the Fox-1 gene family of splicing factors. J Biol Chem (2009) 2.16
Spatially isotropic four-dimensional imaging with dual-view plane illumination microscopy. Nat Biotechnol (2013) 1.92
Disease-associated mutations and alternative splicing alter the enzymatic and motile activity of nonmuscle myosins II-B and II-C. J Biol Chem (2005) 1.86
Confinement-optimized three-dimensional T cell amoeboid motility is modulated via myosin IIA-regulated adhesions. Nat Immunol (2010) 1.82
Vertebrate nonmuscle myosin II isoforms rescue small interfering RNA-induced defects in COS-7 cell cytokinesis. J Biol Chem (2005) 1.77
CENP-E combines a slow, processive motor and a flexible coiled coil to produce an essential motile kinetochore tether. J Cell Biol (2008) 1.77
A point mutation in the motor domain of nonmuscle myosin II-B impairs migration of distinct groups of neurons. Mol Biol Cell (2004) 1.73
A unique role for nonmuscle myosin heavy chain IIA in regulation of epithelial apical junctions. PLoS One (2007) 1.72
The May-Hegglin anomaly gene MYH9 is a negative regulator of platelet biogenesis modulated by the Rho-ROCK pathway. Blood (2007) 1.64
Vinculin-actin interaction couples actin retrograde flow to focal adhesions, but is dispensable for focal adhesion growth. J Cell Biol (2013) 1.63
Microscopy in 3D: a biologist's toolbox. Trends Cell Biol (2011) 1.62
A zyxin-mediated mechanism for actin stress fiber maintenance and repair. Dev Cell (2010) 1.62
Loss of cell adhesion causes hydrocephalus in nonmuscle myosin II-B-ablated and mutated mice. Mol Biol Cell (2007) 1.49
Replacement of nonmuscle myosin II-B with II-A rescues brain but not cardiac defects in mice. J Biol Chem (2007) 1.48
Mouse models of MYH9-related disease: mutations in nonmuscle myosin II-A. Blood (2011) 1.41
Ablation and mutation of nonmuscle myosin heavy chain II-B results in a defect in cardiac myocyte cytokinesis. Circ Res (2003) 1.40
Ablation of nonmuscle myosin II-B and II-C reveals a role for nonmuscle myosin II in cardiac myocyte karyokinesis. Mol Biol Cell (2010) 1.36
Nonmuscle myosin II exerts tension but does not translocate actin in vertebrate cytokinesis. Proc Natl Acad Sci U S A (2012) 1.29
NMII forms a contractile transcellular sarcomeric network to regulate apical cell junctions and tissue geometry. Curr Biol (2013) 1.29
Pak1 regulates focal adhesion strength, myosin IIA distribution, and actin dynamics to optimize cell migration. J Cell Biol (2011) 1.28
Micro-environmental control of cell migration--myosin IIA is required for efficient migration in fibrillar environments through control of cell adhesion dynamics. J Cell Sci (2012) 1.26
Epidermal growth factor-induced contraction regulates paxillin phosphorylation to temporally separate traction generation from de-adhesion. Mol Biol Cell (2009) 1.25
Distinct ECM mechanosensing pathways regulate microtubule dynamics to control endothelial cell branching morphogenesis. J Cell Biol (2011) 1.24
Characterization of three full-length human nonmuscle myosin II paralogs. J Biol Chem (2013) 1.23
Fox-3 and PSF interact to activate neural cell-specific alternative splicing. Nucleic Acids Res (2010) 1.22
Myosin II regulates extension, growth and patterning in the mammalian cochlear duct. Development (2009) 1.19
Non-muscle myosin II regulates survival threshold of pluripotent stem cells. Nat Commun (2010) 1.16
Nonmuscle myosin II isoform and domain specificity during early mouse development. Proc Natl Acad Sci U S A (2010) 1.16
Distinct and redundant roles of the non-muscle myosin II isoforms and functional domains. Biochem Soc Trans (2011) 1.15
Guiding cell migration by tugging. Curr Opin Cell Biol (2013) 1.14
A specific isoform of nonmuscle myosin II-C is required for cytokinesis in a tumor cell line. J Biol Chem (2006) 1.14
Protrusion and actin assembly are coupled to the organization of lamellar contractile structures. Exp Cell Res (2010) 1.12
Non-muscle myosin IIA differentially regulates intestinal epithelial cell restitution and matrix invasion. Am J Pathol (2009) 1.09
A novel guanine nucleotide exchange factor MyoGEF is required for cytokinesis. Cell Cycle (2006) 1.07
Adhesive F-actin waves: a novel integrin-mediated adhesion complex coupled to ventral actin polymerization. PLoS One (2011) 1.07
Menin, a tumor suppressor, associates with nonmuscle myosin II-A heavy chain. Oncogene (2003) 1.06
Induction of nonmuscle myosin heavy chain II-C by butyrate in RAW 264.7 mouse macrophages. J Biol Chem (2003) 1.05
Conditional ablation of nonmuscle myosin II-B delineates heart defects in adult mice. Circ Res (2009) 1.03
Function of the neuron-specific alternatively spliced isoforms of nonmuscle myosin II-B during mouse brain development. Mol Biol Cell (2006) 1.02
Automated screening of microtubule growth dynamics identifies MARK2 as a regulator of leading edge microtubules downstream of Rac1 in migrating cells. PLoS One (2012) 1.01
Sorting nexin 27 protein regulates trafficking of a p21-activated kinase (PAK) interacting exchange factor (β-Pix)-G protein-coupled receptor kinase interacting protein (GIT) complex via a PDZ domain interaction. J Biol Chem (2011) 1.01
Pitx2a expression alters actin-myosin cytoskeleton and migration of HeLa cells through Rho GTPase signaling. Mol Biol Cell (2002) 1.01
Stiffness-controlled three-dimensional extracellular matrices for high-resolution imaging of cell behavior. Nat Protoc (2012) 0.99
An alternatively spliced isoform of non-muscle myosin II-C is not regulated by myosin light chain phosphorylation. J Biol Chem (2009) 0.97
Effects of brefeldin A-inhibited guanine nucleotide-exchange (BIG) 1 and KANK1 proteins on cell polarity and directed migration during wound healing. Proc Natl Acad Sci U S A (2011) 0.96
Orientation-specific responses to sustained uniaxial stretching in focal adhesion growth and turnover. Proc Natl Acad Sci U S A (2013) 0.93
Specification of Architecture and Function of Actin Structures by Actin Nucleation Factors. Annu Rev Biophys (2015) 0.92
Nonmuscle myosin IIB links cytoskeleton to IRE1α signaling during ER stress. Dev Cell (2012) 0.92
Advances in light-based imaging of three-dimensional cellular ultrastructure. Curr Opin Cell Biol (2011) 0.90
The biophysics of asthmatic airway smooth muscle. Respir Physiol Neurobiol (2003) 0.89
Isolation of focal adhesion proteins for biochemical and proteomic analysis. Methods Mol Biol (2012) 0.89
The B2 alternatively spliced isoform of nonmuscle myosin II-B lacks actin-activated MgATPase activity and in vitro motility. Biochem Biophys Res Commun (2007) 0.89
LPA(1) -induced migration requires nonmuscle myosin II light chain phosphorylation in breast cancer cells. J Cell Physiol (2011) 0.88
Nonmuscle myosin II is required for internalization of the epidermal growth factor receptor and modulation of downstream signaling. J Biol Chem (2012) 0.87
Incoherent structured illumination improves optical sectioning and contrast in multiphoton super-resolution microscopy. Opt Express (2015) 0.87
N-cadherin sustains motility and polarity of future cortical interneurons during tangential migration. J Neurosci (2013) 0.84
Event ordering in live-cell imaging determined from temporal cross-correlation asymmetry. Biophys J (2010) 0.84
Rap1 activation in collagen phagocytosis is dependent on nonmuscle myosin II-A. Mol Biol Cell (2008) 0.83
In vivo studies on nonmuscle myosin II expression and function in heart development. Front Biosci (Landmark Ed) (2012) 0.81
Nonmuscle myosin II is a critical regulator of clathrin-mediated endocytosis. Traffic (2014) 0.81
How we discovered fluorescent speckle microscopy. Mol Biol Cell (2011) 0.81
Non-muscle myosin IIB is essential for cytokinesis during male meiotic cell divisions. Dev Biol (2012) 0.79
Probing intracellular force distributions by high-resolution live cell imaging and inverse dynamics. Methods Cell Biol (2007) 0.78
Localization-based super-resolution imaging of cellular structures. Methods Mol Biol (2013) 0.77
Keratin 5-Cre-driven excision of nonmuscle myosin IIA in early embryo trophectoderm leads to placenta defects and embryonic lethality. Dev Biol (2013) 0.77
Model for adhesion clutch explains biphasic relationship between actin flow and traction at the cell leading edge. Phys Biol (2015) 0.76
Spinning disk confocal imaging of neutrophil migration in zebrafish. Methods Mol Biol (2014) 0.76
Margaret Gardel: at the interface of physics and biology. Interview by Caitlin Sedwick. J Cell Biol (2013) 0.75
Corrigendum: Cell migration and antigen capture are antagonistic processes coupled by myosin II in dendritic cells. Nat Commun (2015) 0.75