Published in Langmuir on January 03, 2008
ent-Steroids: novel tools for studies of signaling pathways. Steroids (2008) 1.12
Specificity of cholesterol and analogs to modulate BK channels points to direct sterol-channel protein interactions. J Gen Physiol (2010) 1.01
Characterization of enantiomeric bile acid-induced apoptosis in colon cancer cell lines. J Biol Chem (2008) 1.01
Relationship between phosphatidylinositol 4-phosphate synthesis, membrane organization, and lateral diffusion of PI4KIIalpha at the trans-Golgi network. J Lipid Res (2010) 0.98
Large conductance, calcium- and voltage-gated potassium (BK) channels: regulation by cholesterol. Pharmacol Ther (2012) 0.96
Enantioselective protein-sterol interactions mediate regulation of both prokaryotic and eukaryotic inward rectifier K+ channels by cholesterol. PLoS One (2011) 0.96
Cholesterol effects on BAX pore activation. J Mol Biol (2008) 0.95
Modulating the activity of short arginine-tryptophan containing antibacterial peptides with N-terminal metallocenoyl groups. Beilstein J Org Chem (2012) 0.83
Identification of a cholesterol-binding pocket in inward rectifier K(+) (Kir) channels. Biophys J (2014) 0.75
Distinct mechanisms underlying cholesterol protection against alcohol-induced BK channel inhibition and resulting vasoconstriction. Biochim Biophys Acta (2016) 0.75
Reduced Membrane Cholesterol Limits Pulmonary Endothelial Ca(2+) Entry Following Chronic Hypoxia. Am J Physiol Heart Circ Physiol (2017) 0.75
Human ISL1 heart progenitors generate diverse multipotent cardiovascular cell lineages. Nature (2009) 4.68
Pyrazinamide inhibits trans-translation in Mycobacterium tuberculosis. Science (2011) 4.13
The renewal and differentiation of Isl1+ cardiovascular progenitors are controlled by a Wnt/beta-catenin pathway. Cell Stem Cell (2007) 3.54
Hsp70 stabilizes lysosomes and reverts Niemann-Pick disease-associated lysosomal pathology. Nature (2010) 2.62
Molecular mechanisms of membrane deformation by I-BAR domain proteins. Curr Biol (2009) 2.47
Association analyses identify six new psoriasis susceptibility loci in the Chinese population. Nat Genet (2010) 2.41
Sequence-dependent denaturation energetics: A major determinant in amyloid disease diversity. Proc Natl Acad Sci U S A (2002) 2.25
Anticonvulsant medications extend worm life-span. Science (2005) 2.18
Tissue damage in the amyloidoses: Transthyretin monomers and nonnative oligomers are the major cytotoxic species in tissue culture. Proc Natl Acad Sci U S A (2004) 2.14
Dependence of current and field driven depinning of domain walls on their structure and chirality in permalloy nanowires. Phys Rev Lett (2006) 2.11
The phosphodiesterase-5 inhibitor vardenafil reduces oxidative stress while reversing pulmonary arterial hypertension. Cardiovasc Res (2013) 2.08
The transcription factor STAT-1 couples macrophage synthesis of 25-hydroxycholesterol to the interferon antiviral response. Immunity (2012) 1.96
Neurosteroid access to the GABAA receptor. J Neurosci (2005) 1.95
Complete genome sequence of Paenibacillus polymyxa SC2, a strain of plant growth-promoting Rhizobacterium with broad-spectrum antimicrobial activity. J Bacteriol (2010) 1.76
Sterol intermediates from cholesterol biosynthetic pathway as liver X receptor ligands. J Biol Chem (2006) 1.72
Zipper-like interaction between proteins in adjacent daughter cells mediates protein localization. Genes Dev (2004) 1.72
Oxysterols are allosteric activators of the oncoprotein Smoothened. Nat Chem Biol (2012) 1.72
Pregnane X receptor (PXR) activation: a mechanism for neuroprotection in a mouse model of Niemann-Pick C disease. Proc Natl Acad Sci U S A (2006) 1.62
Mechanisms of neurosteroid interactions with GABA(A) receptors. Pharmacol Ther (2007) 1.60
Phospholipid-cytochrome c interaction: evidence for the extended lipid anchorage. J Biol Chem (2002) 1.58
Identification and characterization of cholest-4-en-3-one, oxime (TRO19622), a novel drug candidate for amyotrophic lateral sclerosis. J Pharmacol Exp Ther (2007) 1.55
Targeted conditional gene knockout in human embryonic stem cells. Cell Res (2010) 1.53
Cholesterol depletion results in site-specific increases in epidermal growth factor receptor phosphorylation due to membrane level effects. Studies with cholesterol enantiomers. J Biol Chem (2003) 1.52
Neuroactive steroids have multiple actions to potentiate GABAA receptors. J Physiol (2004) 1.47
Mutations of the GABA-A receptor alpha1 subunit M1 domain reveal unexpected complexity for modulation by neuroactive steroids. Mol Pharmacol (2008) 1.46
Tubular graphite cones. Science (2003) 1.44
Oscillatory dependence of current-driven magnetic domain wall motion on current pulse length. Nature (2006) 1.42
Retracted Pathological dislocation of the hip due to coxotuberculosis in children: a 29-case report. J Orthop Surg Res (2014) 1.38
Formation of amyloid fibers triggered by phosphatidylserine-containing membranes. Biochemistry (2004) 1.38
Membranes: a meeting point for lipids, proteins and therapies. J Cell Mol Med (2008) 1.37
Natural and enantiomeric etiocholanolone interact with distinct sites on the rat alpha1beta2gamma2L GABAA receptor. Mol Pharmacol (2007) 1.33
Oxidative stress in NPC1 deficient cells: protective effect of allopregnanolone. J Cell Mol Med (2008) 1.33
Dual potentiating and inhibitory actions of a benz[e]indene neurosteroid analog on recombinant alpha1beta2gamma2 GABAA receptors. Mol Pharmacol (2006) 1.31
Neurosteroid analogues. 12. Potent enhancement of GABA-mediated chloride currents at GABAA receptors by ent-androgens. Eur J Med Chem (2007) 1.31
The role of lipid-protein interactions in amyloid-type protein fibril formation. Chem Phys Lipids (2006) 1.25
Effects of natural and enantiomeric cholesterol on the thermotropic phase behavior and structure of egg sphingomyelin bilayer membranes. Biophys J (2003) 1.24
Slow actions of neuroactive steroids at GABAA receptors. J Neurosci (2004) 1.24
Evidence for the lack of a specific interaction between cholesterol and sphingomyelin. Biophys J (2004) 1.23
Selective antagonism of 5alpha-reduced neurosteroid effects at GABA(A) receptors. Mol Pharmacol (2004) 1.23
Inhibitory effect of ginsenoside Rg3 on ovarian cancer metastasis. Chin Med J (Engl) (2008) 1.23
Continuous time random walk model better describes the tailing of atrazine transport in soil. Chemosphere (2008) 1.21
The sticky issue of neurosteroids and GABA(A) receptors. Trends Neurosci (2010) 1.21
Temporin L: antimicrobial, haemolytic and cytotoxic activities, and effects on membrane permeabilization in lipid vesicles. Biochem J (2002) 1.20
3beta -hydroxypregnane steroids are pregnenolone sulfate-like GABA(A) receptor antagonists. J Neurosci (2002) 1.18
Analysis of eight organophosphorus pesticide residues in fresh vegetables retailed in agricultural product markets of Nanjing, China. Bull Environ Contam Toxicol (2008) 1.17
Lower socioeconomic status is associated with worse outcomes in pulmonary arterial hypertension. Am J Respir Crit Care Med (2012) 1.17
Side chain oxygenated cholesterol regulates cellular cholesterol homeostasis through direct sterol-membrane interactions. J Biol Chem (2008) 1.17
Neuroprotective effects of an estratriene analog are estrogen receptor independent in vitro and in vivo. Brain Res (2005) 1.16
Selective T-type calcium channel blockade alleviates hyperalgesia in ob/ob mice. Diabetes (2009) 1.15
Structure and function of the Smoothened extracellular domain in vertebrate Hedgehog signaling. Elife (2013) 1.15
Chromatin immunoprecipitation-based screen to identify functional genomic binding sites for sequence-specific transactivators. Mol Cell Biol (2005) 1.15
Binding of LL-37 to model biomembranes: insight into target vs host cell recognition. Biochim Biophys Acta (2007) 1.15
The influence of neuroactive steroid lipophilicity on GABAA receptor modulation: evidence for a low-affinity interaction. J Neurophysiol (2009) 1.14
Targeting activin receptor-like kinase 1 inhibits angiogenesis and tumorigenesis through a mechanism of action complementary to anti-VEGF therapies. Cancer Res (2011) 1.13
Resonant amplification of magnetic domain-wall motion by a train of current pulses. Science (2007) 1.13
352 nm ultraviolet emission from high-quality crystalline AlN whiskers. Nanotechnology (2010) 1.12
Neurosteroids, stress and depression: potential therapeutic opportunities. Neurosci Biobehav Rev (2012) 1.12
Energetics by NMR: site-specific binding in a positively cooperative system. Proc Natl Acad Sci U S A (2002) 1.11
Gastrointestinal absorption and plasma kinetics of soy Delta(5)-phytosterols and phytostanols in humans. Am J Physiol Endocrinol Metab (2002) 1.11
First synthesis of ent-desmosterol and its conversion to ent-deuterocholesterol. Steroids (2003) 1.10
Estrogen-like compounds for ischemic neuroprotection. Stroke (2004) 1.10
Application of canonical correspondence analysis to determine the ecological contribution of phytoplankton to PCBs bioaccumulation in Qinhuai River, Nanjing, China. Environ Sci Pollut Res Int (2013) 1.10
Suffering from loneliness indicates significant mortality risk of older people. J Aging Res (2011) 1.09
Characterization of two oxidatively modified phospholipids in mixed monolayers with DPPC. Biophys J (2006) 1.08
Inhibitory effect of ginsenoside Rg3 combined with cyclophosphamide on growth and angiogenesis of ovarian cancer. Chin Med J (Engl) (2007) 1.07
Interaction of the antimicrobial peptide pheromone Plantaricin A with model membranes: implications for a novel mechanism of action. Biochim Biophys Acta (2006) 1.07
Dynamic processes involved in the pre-vascularization of silk fibroin constructs for bone regeneration using outgrowth endothelial cells. Biomaterials (2008) 1.07
Neurosteroid migration to intracellular compartments reduces steroid concentration in the membrane and diminishes GABA-A receptor potentiation. J Physiol (2007) 1.07
Neuroprotective effects of 17beta-estradiol and nonfeminizing estrogens against H2O2 toxicity in human neuroblastoma SK-N-SH cells. Mol Pharmacol (2006) 1.06
[The influence of simulated acid rain on acidity and K+ leaching regulation of different soil layers]. Huan Jing Ke Xue (2003) 1.06
Investigating the allosterism of acyl-CoA:cholesterol acyltransferase (ACAT) by using various sterols: in vitro and intact cell studies. Biochem J (2005) 1.06
Free solution hydrodynamic separation of DNA fragments from 75 to 106,000 base pairs in a single run. J Am Chem Soc (2010) 1.06
Neurosteroid analog photolabeling of a site in the third transmembrane domain of the β3 subunit of the GABA(A) receptor. Mol Pharmacol (2012) 1.05
Localization of translocation complex components in Bacillus subtilis: enrichment of the signal recognition particle receptor at early sporulation septa. J Bacteriol (2005) 1.03
Neurosteroids enhance spontaneous glutamate release in hippocampal neurons. Possible role of metabotropic sigma1-like receptors. J Biol Chem (2002) 1.03
Anticonvulsant and anesthetic effects of a fluorescent neurosteroid analog activated by visible light. Nat Neurosci (2007) 1.03
Hepcidin is directly regulated by insulin and plays an important role in iron overload in streptozotocin-induced diabetic rats. Diabetes (2013) 1.02
Binding of the antimicrobial peptide temporin L to liposomes assessed by Trp fluorescence. J Biol Chem (2002) 1.02
Characterization of enantiomeric bile acid-induced apoptosis in colon cancer cell lines. J Biol Chem (2008) 1.01
GABAergic neurosteroids mediate the effects of ethanol on long-term potentiation in rat hippocampal slices. Eur J Neurosci (2007) 1.01
Vardenafil in pulmonary arterial hypertension: a randomized, double-blind, placebo-controlled study. Am J Respir Crit Care Med (2011) 1.01
Potent and selective structure-based dibenzofuran inhibitors of transthyretin amyloidogenesis: kinetic stabilization of the native state. J Am Chem Soc (2005) 1.01
Photoaffinity labeling with a neuroactive steroid analogue. 6-azi-pregnanolone labels voltage-dependent anion channel-1 in rat brain. J Biol Chem (2003) 1.01
Neuroprotective effects of a novel non-receptor-binding estrogen analogue: in vitro and in vivo analysis. Stroke (2002) 1.01
Neuroactive steroids and human recombinant rho1 GABAC receptors. J Pharmacol Exp Ther (2007) 1.00
Binding of lysozyme to phospholipid bilayers: evidence for protein aggregation upon membrane association. Biophys J (2007) 1.00
Islet amyloid polypeptide forms rigid lipid-protein amyloid fibrils on supported phospholipid bilayers. J Mol Biol (2007) 0.99
Regulation of sodium and calcium channels by signaling complexes. J Recept Signal Transduct Res (2006) 0.99
Synthesis, characterization, and receptor interaction profiles of enantiomeric bile acids. J Med Chem (2007) 0.99
Role of relative size of asperities and adhering particles on the adhesion force. J Colloid Interface Sci (2013) 0.99
Modulation of the activity of secretory phospholipase A2 by antimicrobial peptides. Antimicrob Agents Chemother (2003) 0.99
Binding of amphipathic alpha-helical antimicrobial peptides to lipid membranes: lessons from temporins B and L. Biochim Biophys Acta (2009) 0.99
Neurosteroid analogues. 14. Alternative ring system scaffolds: GABA modulatory and anesthetic actions of cyclopenta[b]phenanthrenes and cyclopenta[b]anthracenes. J Med Chem (2008) 0.98
Isolation and characterization of 1,2,4-trichlorobenzene mineralizing Bordetella sp. and its bioremediation potential in soil. Chemosphere (2007) 0.98
Relationship between phosphatidylinositol 4-phosphate synthesis, membrane organization, and lateral diffusion of PI4KIIalpha at the trans-Golgi network. J Lipid Res (2010) 0.98