PubRank

Manuel Benito

Author PubWeight™ 52.55‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 The epithelial mesenchymal transition confers resistance to the apoptotic effects of transforming growth factor Beta in fetal rat hepatocytes. Mol Cancer Res 2002 2.01
2 P38 alpha mitogen-activated protein kinase sensitizes cells to apoptosis induced by different stimuli. Mol Biol Cell 2003 1.65
3 Molecular mechanisms of insulin resistance in IRS-2-deficient hepatocytes. Diabetes 2003 1.51
4 Autophagy impairment aggravates the inhibitory effects of high glucose on osteoblast viability and function. Biochem J 2013 1.46
5 Novel adipocyte lines from brown fat: a model system for the study of differentiation, energy metabolism, and insulin action. Bioessays 2002 1.30
6 Correlations of telomere length, telomerase activity, and telomeric-repeat binding factor 1 expression in colorectal carcinoma. Cancer 2006 1.20
7 Telomere shortening is associated with poor prognosis and telomerase activity correlates with DNA repair impairment in non-small cell lung cancer. Lung Cancer 2008 1.03
8 Developmental switch from prolonged insulin action to increased insulin sensitivity in protein tyrosine phosphatase 1B-deficient hepatocytes. Endocrinology 2006 1.02
9 Insulin restores differentiation of Ras-transformed C2C12 myoblasts by inducing NF-kappaB through an AKT/P70S6K/p38-MAPK pathway. Oncogene 2002 1.02
10 Prevalence of germline mutations of MLH1 and MSH2 in hereditary nonpolyposis colorectal cancer families from Spain. Int J Cancer 2002 1.02
11 Rosiglitazone and retinoic acid induce uncoupling protein-1 (UCP-1) in a p38 mitogen-activated protein kinase-dependent manner in fetal primary brown adipocytes. J Biol Chem 2002 1.00
12 Levels of protein tyrosine phosphatase 1B determine susceptibility to apoptosis in serum-deprived hepatocytes. J Cell Physiol 2007 1.00
13 Transforming growth factor-beta activates both pro-apoptotic and survival signals in fetal rat hepatocytes. Exp Cell Res 2004 1.00
14 Immunohistochemistry and microsatellite instability testing for selecting MLH1, MSH2 and MSH6 mutation carriers in hereditary non-polyposis colorectal cancer. Oncol Rep 2004 0.98
15 IRS-2 mediates the antiapoptotic effect of insulin in neonatal hepatocytes. Hepatology 2004 0.98
16 Biological and clinical significance of MMP-2, MMP-9, TIMP-1 and TIMP-2 in non-small cell lung cancer. Oncol Rep 2007 0.98
17 Beta-Cell hyperplasia induced by hepatic insulin resistance: role of a liver-pancreas endocrine axis through insulin receptor A isoform. Diabetes 2009 0.96
18 Cooperative role of telomerase activity and p16 expression in the prognosis of non-small-cell lung cancer. J Clin Oncol 2002 0.94
19 Differential Wnt pathway gene expression and E-cadherin truncation in sporadic colorectal cancers with and without microsatellite instability. Clin Cancer Res 2008 0.94
20 Insulin-induced up-regulated uncoupling protein-1 expression is mediated by insulin receptor substrate 1 through the phosphatidylinositol 3-kinase/Akt signaling pathway in fetal brown adipocytes. J Biol Chem 2003 0.94
21 Negative regulation of Akt activity by p38alpha MAP kinase in cardiomyocytes involves membrane localization of PP2A through interaction with caveolin-1. Cell Signal 2006 0.93
22 Overexpression of SPARC protein contrasts with its transcriptional silencing by aberrant hypermethylation of SPARC CpG-rich region in endometrial carcinoma. Oncol Rep 2007 0.93
23 Increased insulin sensitivity in IGF-I receptor--deficient brown adipocytes. Diabetes 2002 0.93
24 Autophagy plays a protective role in endoplasmic reticulum stress-mediated pancreatic β cell death. Autophagy 2012 0.92
25 The brown adipose cell: a unique model for understanding the molecular mechanism of insulin resistance. Mini Rev Med Chem 2005 0.91
26 Differential colorectal carcinogenesis: Molecular basis and clinical relevance. World J Gastrointest Oncol 2010 0.90
27 Susceptibility to apoptosis in insulin-like growth factor-I receptor-deficient brown adipocytes. Mol Biol Cell 2004 0.87
28 Methylation profiling in non-small cell lung cancer: clinical implications. Int J Oncol 2011 0.86
29 Role of insulin receptor and balance in insulin receptor isoforms A and B in regulation of apoptosis in simian virus 40-immortalized neonatal hepatocytes. Mol Biol Cell 2008 0.85
30 Essential role of insulin-like growth factor I receptor in insulin-induced fetal brown adipocyte differentiation. Endocrinology 2003 0.85
31 Brown fat lipoatrophy and increased visceral adiposity through a concerted adipocytokines overexpression induces vascular insulin resistance and dysfunction. Endocrinology 2012 0.84
32 cIAP-1, but not XIAP, is cleaved by caspases during the apoptosis induced by TGF-beta in fetal rat hepatocytes. FEBS Lett 2002 0.84
33 Role of insulin receptor in the regulation of glucose uptake in neonatal hepatocytes. Endocrinology 2006 0.84
34 C3G down-regulates p38 MAPK activity in response to stress by Rap-1 independent mechanisms: involvement in cell death. Cell Signal 2010 0.84
35 Stromelysin-1 promoter mutations impair gelatinase B activation in high microsatellite instability sporadic colorectal tumors. Cancer Res 2002 0.83
36 Differential role of PPAR gamma in the regulation of UCP-1 and adipogenesis by TNF-alpha in brown adipocytes. FEBS Lett 2002 0.83
37 Poly (ADP-ribose) polymerase 3 (PARP3), a potential repressor of telomerase activity. J Exp Clin Cancer Res 2014 0.82
38 MMP-7 and SGCE as distinctive molecular factors in sporadic colorectal cancers from the mutator phenotype pathway. Int J Oncol 2010 0.82
39 PTP1B deficiency increases glucose uptake in neonatal hepatocytes: involvement of IRA/GLUT2 complexes. Am J Physiol Gastrointest Liver Physiol 2008 0.82
40 Role of the TSC1-TSC2 complex in the integration of insulin and glucose signaling involved in pancreatic beta-cell proliferation. Endocrinology 2010 0.82
41 Genomic organization of a novel glycosylphosphatidylinositol MAM gene expressed in human tissues and tumors. Oncogene 2002 0.82
42 Expression of MMP-9 and TIMP-1 as prognostic markers in gastric carcinoma. Hepatogastroenterology 2007 0.82
43 p38alpha MAPK can positively or negatively regulate Rac-1 activity depending on the presence of serum. FEBS Lett 2007 0.81
44 Atypical beta-adrenergic effects on insulin signaling and action in beta(3)-adrenoceptor-deficient brown adipocytes. Am J Physiol Endocrinol Metab 2002 0.81
45 Implication of insulin receptor A isoform and IRA/IGF-IR hybrid receptors in the aortic vascular smooth muscle cell proliferation: role of TNF-α and IGF-II. Endocrinology 2013 0.80
46 Differential impact of p16 inactivation by promoter methylation in non-small cell lung and colorectal cancer: clinical implications. Int J Oncol 2004 0.80
47 Differential expression of senescence and cell death factors in non-small cell lung and colorectal tumors showing telomere attrition. Oncology 2012 0.80
48 Telomere function in colorectal cancer. World J Gastrointest Oncol 2009 0.79
49 Antagonistic effect of TNF-alpha and insulin on uncoupling protein 2 (UCP-2) expression and vascular damage. Cardiovasc Diabetol 2014 0.79
50 Expression of Human MDGA1 Increases Cell Motility and Cell-Cell Adhesion and Reduces Adhesion to Extracellular Matrix Proteins in MDCK Cells. Cancer Microenviron 2010 0.78
51 Role of IRS-3 in the insulin signaling of IRS-1-deficient brown adipocytes. J Biol Chem 2003 0.78
52 Impairment of stromelysin-1 transcriptional activity by promoter mutations in high microsatellite instability colorectal tumors. Cancer Res 2005 0.77
53 IRS-3 mediates insulin-induced glucose uptake in differentiated IRS-2(-/-) brown adipocytes. Mol Cell Endocrinol 2006 0.77
54 Concerted expression of the thermogenic and bioenergetic mitochondrial protein machinery in brown adipose tissue. J Cell Biochem 2013 0.77
55 Long-term treatment with insulin induces apoptosis in brown adipocytes: role of oxidative stress. Endocrinology 2003 0.77
56 [Role of white adipose tissue in vascular complications due to obesity]. Clin Investig Arterioscler 2013 0.76
57 Measurement invariance of the Satisfaction With Life Scale (SWLS)by country, gender and age. Psicothema 2017 0.75
58 [Role of brown and perivascular adipose tissue in vascular complications due to obesity]. Clin Investig Arterioscler 2013 0.75
59 Essential role of protein kinase C zeta in the impairment of insulin-induced glucose transport in IRS-2-deficient brown adipocytes. FEBS Lett 2003 0.75