Published in BMC Genet on January 08, 2008
Guidelines for investigating causality of sequence variants in human disease. Nature (2014) 7.30
Genome-wide generation and systematic phenotyping of knockout mice reveals new roles for many genes. Cell (2013) 3.47
The mammalian phenotype ontology: enabling robust annotation and comparative analysis. Wiley Interdiscip Rev Syst Biol Med (2010) 3.00
Acute or chronic upregulation of mitochondrial fatty acid oxidation has no net effect on whole-body energy expenditure or adiposity. Cell Metab (2010) 2.44
The QTN program and the alleles that matter for evolution: all that's gold does not glitter. Evolution (2011) 2.23
Lack of exercise is a major cause of chronic diseases. Compr Physiol (2012) 2.19
Robust and sensitive analysis of mouse knockout phenotypes. PLoS One (2012) 1.35
Tilting at quixotic trait loci (QTL): an evolutionary perspective on genetic causation. Genetics (2008) 1.33
Colloquium papers: Numbering the hairs on our heads: the shared challenge and promise of phenomics. Proc Natl Acad Sci U S A (2009) 1.31
Genetic architecture of body size in mammals. Genome Biol (2012) 1.03
PhenStat: A Tool Kit for Standardized Analysis of High Throughput Phenotypic Data. PLoS One (2015) 1.00
Genome partitioning of genetic variation for milk production and composition traits in holstein cattle. Front Genet (2011) 1.00
Genome-wide association analysis for quantitative trait loci influencing Warner-Bratzler shear force in five taurine cattle breeds. Anim Genet (2012) 0.98
Lrig2-deficient mice are protected against PDGFB-induced glioma. PLoS One (2013) 0.91
Predisposition to late-onset obesity in GIRK4 knockout mice. Proc Natl Acad Sci U S A (2008) 0.89
Obesity genetics in mouse and human: back and forth, and back again. PeerJ (2015) 0.89
The fat tail of obesity as told by the genome. Curr Opin Clin Nutr Metab Care (2008) 0.88
Retinal degeneration increases susceptibility to myopia in mice. Mol Vis (2013) 0.87
QTL analysis of dietary obesity in C57BL/6byj X 129P3/J F2 mice: diet- and sex-dependent effects. PLoS One (2013) 0.86
The fallacy of ratio correction to address confounding factors. Lab Anim (2012) 0.86
Potential clinical translation of juvenile rodent inactivity models to study the onset of childhood obesity. Am J Physiol Regul Integr Comp Physiol (2012) 0.84
Reporting phenotypes in mouse models when considering body size as a potential confounder. J Biomed Semantics (2016) 0.82
The Poly(C) Binding Protein Pcbp2 and Its Retrotransposed Derivative Pcbp1 Are Independently Essential to Mouse Development. Mol Cell Biol (2015) 0.82
Histone demethylase jumonji AT-rich interactive domain 1B (JARID1B) controls mammary gland development by regulating key developmental and lineage specification genes. J Biol Chem (2014) 0.81
Multiple phenotypic changes in mice after knockout of the B3gnt5 gene, encoding Lc3 synthase--a key enzyme in lacto-neolacto ganglioside synthesis. BMC Dev Biol (2010) 0.80
Enteropeptidase: a gene associated with a starvation human phenotype and a novel target for obesity treatment. PLoS One (2012) 0.80
A review of standardized metabolic phenotyping of animal models. Mamm Genome (2014) 0.80
Body fat distribution and organ weights of 14 common strains and a 22-strain consomic panel of rats. Physiol Behav (2011) 0.80
Genetics of Rapid and Extreme Size Evolution in Island Mice. Genetics (2015) 0.79
Tagging methyl-CpG-binding domain proteins reveals different spatiotemporal expression and supports distinct functions. Epigenomics (2016) 0.79
Induction of body weight loss through RNAi-knockdown of APOBEC1 gene expression in transgenic rabbits. PLoS One (2014) 0.77
Obesity as a perceived social signal. PLoS One (2008) 0.76
Body Composition QTLs Identified in Intercross Populations Are Reproducible in Consomic Mouse Strains. PLoS One (2015) 0.76
Novel Endothelial Cell-Specific AQP1 Knockout Mice Confirm the Crucial Role of Endothelial AQP1 in Ultrafiltration during Peritoneal Dialysis. PLoS One (2016) 0.75
A disputed evidence on obesity: comparison of the effects of Rcan2(-/-) and Rps6kb1(-/-) mutations on growth and body weight in C57BL/6J mice. J Zhejiang Univ Sci B (2016) 0.75
Candidate-gene criteria for clinical reporting: diagnostic exome sequencing identifies altered candidate genes among 8% of patients with undiagnosed diseases. Genet Med (2016) 0.75
C4.4A gene ablation is compatible with normal epidermal development and causes modest overt phenotypes. Sci Rep (2016) 0.75
Skeletal muscle mitochondrial uncoupling prevents diabetes but not obesity in NZO mice, a model for polygenic diabesity. Genes Nutr (2015) 0.75
Transcriptional Coactivator and Chromatin Protein PC4 Is Involved in Hippocampal Neurogenesis and Spatial Memory Extinction. J Biol Chem (2016) 0.75
The role of sex and body weight on the metabolic effects of high-fat diet in C57BL/6N mice. Nutr Diabetes (2017) 0.75
Functional characterization of the S. cerevisiae genome by gene deletion and parallel analysis. Science (1999) 36.25
Functional profiling of the Saccharomyces cerevisiae genome. Nature (2002) 36.10
Systematic functional analysis of the Caenorhabditis elegans genome using RNAi. Nature (2003) 26.58
Ensembl 2006. Nucleic Acids Res (2006) 11.66
Large-scale analysis of the yeast genome by transposon tagging and gene disruption. Nature (1999) 9.87
A mouse for all reasons. Cell (2007) 9.01
The BDGP gene disruption project: single transposon insertions associated with 40% of Drosophila genes. Genetics (2004) 8.40
The Mouse Genome Database (MGD): from genes to mice--a community resource for mouse biology. Nucleic Acids Res (2005) 8.19
The knockout mouse project. Nat Genet (2004) 7.80
Understanding mammalian genetic systems: the challenge of phenotyping in the mouse. PLoS Genet (2006) 3.14
Genetic determinants of energy expenditure and insulin resistance in diet-induced obesity in mice. Diabetes (2004) 2.54
Inheritance in the House Mouse, the Linkage Relations of Short-Ear, Hairless, and Naked. Genetics (1931) 2.15
Is the energy homeostasis system inherently biased toward weight gain? Diabetes (2003) 2.14
Mapping of quantitative trait loci with knockout/congenic strains. Genome Res (2001) 2.03
Knockout mice: simple solutions to the problems of genetic background and flanking genes. Trends Neurosci (2002) 1.96
Quantitative trait loci that determine plasma lipids and obesity in C57BL/6J and 129S1/SvImJ inbred mice. J Lipid Res (2004) 1.28
Interpretation of knockout experiments: the congenic footprint. Genes Brain Behav (2007) 1.11
Loci on chromosomes 2, 4, 9, and 16 for body weight, body length, and adiposity identified in a genome scan of an F2 intercross between the 129P3/J and C57BL/6ByJ mouse strains. Mamm Genome (2003) 1.11
Quantitative trait loci for individual adipose depot weights in C57BL/6ByJ x 129P3/J F2 mice. Mamm Genome (2006) 1.05
Food intake, water intake, and drinking spout side preference of 28 mouse strains. Behav Genet (2002) 3.26
CALHM1 ion channel mediates purinergic neurotransmission of sweet, bitter and umami tastes. Nature (2013) 2.08
Voluntary consumption of NaCl, KCl, CaCl2, and NH4Cl solutions by 28 mouse strains. Behav Genet (2002) 1.44
Allelic variation of the Tas1r3 taste receptor gene selectively affects behavioral and neural taste responses to sweeteners in the F2 hybrids between C57BL/6ByJ and 129P3/J mice. J Neurosci (2004) 1.43
Chemosensory factors influencing alcohol perception, preferences, and consumption. Alcohol Clin Exp Res (2003) 1.35
Preferences of 14 rat strains for 17 taste compounds. Physiol Behav (2008) 1.23
Forty mouse strain survey of body composition. Physiol Behav (2007) 1.12
Loci on chromosomes 2, 4, 9, and 16 for body weight, body length, and adiposity identified in a genome scan of an F2 intercross between the 129P3/J and C57BL/6ByJ mouse strains. Mamm Genome (2003) 1.11
Voluntary ethanol consumption by mice: genome-wide analysis of quantitative trait loci and their interactions in a C57BL/6ByJ x 129P3/J F2 intercross. Genome Res (2002) 1.07
Quantitative trait loci for individual adipose depot weights in C57BL/6ByJ x 129P3/J F2 mice. Mamm Genome (2006) 1.05
Calcium deprivation increases the palatability of calcium solutions in rats. Physiol Behav (2005) 0.99
Genetic, physical, and comparative map of the subtelomeric region of mouse Chromosome 4. Mamm Genome (2002) 0.96
No relationship between sequence variation in protein coding regions of the Tas1r3 gene and saccharin preference in rats. Chem Senses (2005) 0.94
Glutamate taste and appetite in laboratory mice: physiologic and genetic analyses. Am J Clin Nutr (2009) 0.92
Genetic analysis of chemosensory traits in human twins. Chem Senses (2012) 0.91
Pica as an adaptive response: Kaolin consumption helps rats recover from chemotherapy-induced illness. Physiol Behav (2009) 0.90
No effect of dietary calcium on body weight of lean and obese mice and rats. Am J Physiol Regul Integr Comp Physiol (2003) 0.89
Magnesium appetite in the rat. Appetite (2002) 0.87
A locus on mouse Chromosome 9 (Adip5) affects the relative weight of the gonadal but not retroperitoneal adipose depot. Mamm Genome (2006) 0.87
Genetic loci affecting body weight and fatness in a C57BL/6J x PWK/PhJ mouse intercross. Mamm Genome (2007) 0.86
QTL analysis of dietary obesity in C57BL/6byj X 129P3/J F2 mice: diet- and sex-dependent effects. PLoS One (2013) 0.86
Taste and acceptance of pyrophosphates by rats and mice. Am J Physiol Regul Integr Comp Physiol (2007) 0.82
Itpr3 Is responsible for the mouse tufted (tf) locus. J Hered (2012) 0.80
Body fat distribution and organ weights of 14 common strains and a 22-strain consomic panel of rats. Physiol Behav (2011) 0.80
Comparison of differences between PWD/PhJ and C57BL/6J mice in calcium solution preferences and chorda tympani nerve responses. Physiol Behav (2011) 0.79
Lesions of the subfornical organ decrease the calcium appetite of calcium-deprived rats. Physiol Behav (2003) 0.79
Chorda tympani nerve modulates the rat's avoidance of calcium chloride. Physiol Behav (2011) 0.77
Influence of the number of repellent-treated and untreated food or water containers on intake by the European starling. Appetite (2005) 0.76
Influence of estrous and circadian cycles on calcium intake of the rat. Physiol Behav (2013) 0.75
Influence of cross-fostering on preference for calcium chloride in C57BL/6J and PWK/PhJ mice. Physiol Behav (2013) 0.75