Cilia orientation and the fluid mechanics of development.

PubWeight™: 1.62‹?› | Rank: Top 4%

🔗 View Article (PMC 2720100)

Published in Curr Opin Cell Biol on January 14, 2008

Authors

Wallace F Marshall1, Christopher Kintner

Author Affiliations

1: Department of Biochemistry & Biophysics, UCSF, San Fransciso, CA 94158, USA. wmarshall@biochem.ucsf.edu

Articles citing this

The vertebrate primary cilium in development, homeostasis, and disease. Cell (2009) 5.29

Coupling between hydrodynamic forces and planar cell polarity orients mammalian motile cilia. Nat Cell Biol (2010) 2.67

The forkhead protein Foxj1 specifies node-like cilia in Xenopus and zebrafish embryos. Nat Genet (2008) 2.31

Lack of cadherins Celsr2 and Celsr3 impairs ependymal ciliogenesis, leading to fatal hydrocephalus. Nat Neurosci (2010) 2.18

The PCP pathway instructs the planar orientation of ciliated cells in the Xenopus larval skin. Curr Biol (2009) 1.87

Planar polarization of node cells determines the rotational axis of node cilia. Nat Cell Biol (2010) 1.83

Cilia organize ependymal planar polarity. J Neurosci (2010) 1.80

Fused has evolved divergent roles in vertebrate Hedgehog signalling and motile ciliogenesis. Nature (2009) 1.69

Mechanical Strain Determines the Axis of Planar Polarity in Ciliated Epithelia. Curr Biol (2015) 1.52

Planar cell polarity enables posterior localization of nodal cilia and left-right axis determination during mouse and Xenopus embryogenesis. PLoS One (2010) 1.49

Basal body stability and ciliogenesis requires the conserved component Poc1. J Cell Biol (2009) 1.38

Multiciliated cells. Curr Biol (2014) 1.23

Primary cilia in planar cell polarity regulation of the inner ear. Curr Top Dev Biol (2008) 1.23

Deuterosome-mediated centriole biogenesis. Dev Cell (2013) 1.12

A dual role for planar cell polarity genes in ciliated cells. Proc Natl Acad Sci U S A (2014) 1.11

Shaping the nervous system: role of the core planar cell polarity genes. Nat Rev Neurosci (2013) 1.11

Building blocks of the nexin-dynein regulatory complex in Chlamydomonas flagella. J Biol Chem (2011) 1.08

Centrosome positioning in vertebrate development. J Cell Sci (2012) 1.03

Loss of Dishevelleds disrupts planar polarity in ependymal motile cilia and results in hydrocephalus. Neuron (2014) 0.99

Regulation of ciliary motility: conserved protein kinases and phosphatases are targeted and anchored in the ciliary axoneme. Arch Biochem Biophys (2011) 0.97

Regulation of cytoskeletal organization and junctional remodeling by the atypical cadherin Fat. Development (2013) 0.97

Site-specific basal body duplication in Chlamydomonas. Cytoskeleton (Hoboken) (2013) 0.95

The two domains of centrin have distinct basal body functions in Tetrahymena. Mol Biol Cell (2011) 0.93

Melanin-concentrating hormone regulates beat frequency of ependymal cilia and ventricular volume. Nat Neurosci (2013) 0.92

Epithelial sodium channels (ENaC) are uniformly distributed on motile cilia in the oviduct and the respiratory airways. Histochem Cell Biol (2011) 0.90

Origins of cellular geometry. BMC Biol (2011) 0.89

Bbof1 is required to maintain cilia orientation. Development (2013) 0.89

DisAp-dependent striated fiber elongation is required to organize ciliary arrays. J Cell Biol (2014) 0.86

The two human centrin homologues have similar but distinct functions at Tetrahymena basal bodies. Mol Biol Cell (2012) 0.85

Three-dimensional structure of the Trypanosome flagellum suggests that the paraflagellar rod functions as a biomechanical spring. PLoS One (2012) 0.85

Cryo-electron tomography reveals ciliary defects underlying human RSPH1 primary ciliary dyskinesia. Nat Commun (2014) 0.84

Axonemal positioning and orientation in three-dimensional space for primary cilia: what is known, what is assumed, and what needs clarification. Dev Dyn (2011) 0.80

Basal foot MTOC organizes pillar MTs required for coordination of beating cilia. Nat Commun (2014) 0.79

Alix-mediated assembly of the actomyosin-tight junction polarity complex preserves epithelial polarity and epithelial barrier. Nat Commun (2016) 0.79

ATP4a is required for development and function of the Xenopus mucociliary epidermis - a potential model to study proton pump inhibitor-associated pneumonia. Dev Biol (2015) 0.79

Planar Organization of Multiciliated Ependymal (E1) Cells in the Brain Ventricular Epithelium. Trends Neurosci (2016) 0.77

Automated image analysis reveals the dynamic 3-dimensional organization of multi-ciliary arrays. Biol Open (2015) 0.77

Physical limits of flow sensing in the left-right organizer. Elife (2017) 0.76

Ciliary and non-ciliary expression and function of PACRG during vertebrate development. Cilia (2012) 0.76

Mechanobiology of Ciliogenesis. Bioscience (2014) 0.76

Cilia distribution and polarity in the epithelial lining of the mouse middle ear cavity. Sci Rep (2017) 0.75

Asymmetrically localized proteins stabilize basal bodies against ciliary beating forces. J Cell Biol (2016) 0.75

Prenatal hyperbaric normoxia treatment improves healthspan and regulates chitin metabolic genes in Drosophila melanogaster. Aging (Albany NY) (2016) 0.75

What we can learn from a tadpole about ciliopathies and airway diseases - Using systems biology in Xenopus to study cilia and mucociliary epithelia. Genesis (2017) 0.75

Emergence of polar order and cooperativity in hydrodynamically coupled model cilia. J R Soc Interface (2013) 0.75

Various facets of vertebrate cilia: motility, signaling, and role in adult neurogenesis. Proc Jpn Acad Ser B Phys Biol Sci (2009) 0.75

Establishment of lateral organ asymmetries in the invertebrate chordate, Ciona intestinalis. Evodevo (2017) 0.75

Articles cited by this

Randomization of left-right asymmetry due to loss of nodal cilia generating leftward flow of extraembryonic fluid in mice lacking KIF3B motor protein. Cell (1998) 8.16

Identification of Vangl2 and Scrb1 as planar polarity genes in mammals. Nature (2003) 4.56

Kupffer's vesicle is a ciliated organ of asymmetry in the zebrafish embryo that initiates left-right development of the brain, heart and gut. Development (2005) 4.24

New neurons follow the flow of cerebrospinal fluid in the adult brain. Science (2006) 3.98

Ciliogenesis defects in embryos lacking inturned or fuzzy function are associated with failure of planar cell polarity and Hedgehog signaling. Nat Genet (2006) 3.97

Tissue/planar cell polarity in vertebrates: new insights and new questions. Development (2007) 3.66

Determination of left-right patterning of the mouse embryo by artificial nodal flow. Nature (2002) 3.61

Mechanism of nodal flow: a conserved symmetry breaking event in left-right axis determination. Cell (2005) 3.01

Planar cell polarity: one or two pathways? Nat Rev Genet (2007) 2.90

A positive feedback mechanism governs the polarity and motion of motile cilia. Nature (2007) 2.44

De novo formation of left-right asymmetry by posterior tilt of nodal cilia. PLoS Biol (2005) 2.42

Cilia-related diseases. J Pathol (2004) 2.39

How molecular motors shape the flagellar beat. HFSP J (2007) 2.27

RhoA-mediated apical actin enrichment is required for ciliogenesis and promoted by Foxj1. J Cell Sci (2007) 2.14

Molecular basis of the effects of mechanical stretch on vascular smooth muscle cells. J Biomech (2006) 2.02

Cilia-driven leftward flow determines laterality in Xenopus. Curr Biol (2007) 1.97

Regulation of primary cilia formation and left-right patterning in zebrafish by a noncanonical Wnt signaling mediator, duboraya. Nat Genet (2006) 1.76

Fluid-dynamical basis of the embryonic development of left-right asymmetry in vertebrates. Proc Natl Acad Sci U S A (2004) 1.74

oko meduzy and related crumbs genes are determinants of apical cell features in the vertebrate embryo. Curr Biol (2006) 1.68

The von Hippel-Lindau tumor suppressor protein controls ciliogenesis by orienting microtubule growth. J Cell Biol (2006) 1.66

Planar cell polarity, ciliogenesis and neural tube defects. Hum Mol Genet (2006) 1.65

PAR proteins and the cytoskeleton: a marriage of equals. Curr Opin Cell Biol (2005) 1.62

A novel Crumbs3 isoform regulates cell division and ciliogenesis via importin beta interactions. J Cell Biol (2007) 1.53

Spontaneous creation of macroscopic flow and metachronal waves in an array of cilia. Biophys J (2006) 1.32

Cytochalasin D inhibits basal body migration and ciliary elongation in quail oviduct epithelium. Cell Tissue Res (1990) 1.29

Xenopus TRPN1 (NOMPC) localizes to microtubule-based cilia in epithelial cells, including inner-ear hair cells. Proc Natl Acad Sci U S A (2005) 1.28

New functions for a vertebrate Rho guanine nucleotide exchange factor in ciliated epithelia. Development (2007) 1.26

Development of order during ciliogenesis. Anat Rec (1968) 1.18

Determination of ciliary polarity precedes differentiation in the epithelial cells of quail oviduct. Biol Cell (1991) 1.16

The orientation of ciliary basal bodies in quail oviduct is related to the ciliary beating cycle commencement. Biol Cell (1985) 1.11

Polarities of the centriolar structure: morphogenetic consequences. Biol Cell (2001) 1.09

The role of cortical orientation in the control of the direction of ciliary beat in Paramecium. J Cell Biol (1975) 1.07

Immunocytochemical localization of myosin during ciliogenesis of quail oviduct. Eur J Cell Biol (1987) 0.99

Ciliogenesis and ciliary abnormalities. Med Electron Microsc (2000) 0.98

Ciliary disorientation alone as a cause of primary ciliary dyskinesia syndrome. Am J Respir Crit Care Med (1996) 0.95

Development of macrociliary cells in Beroë. I. Actin bundles and centriole migration. J Cell Sci (1988) 0.91

The secondary nature of ciliary (dis)orientation in secondary and primary ciliary dyskinesia. Acta Otolaryngol (2004) 0.90

Primary ciliary dyskinesia syndrome associated with abnormal ciliary orientation in infants. Eur Respir J (2001) 0.87

Ciliary orientation in the "immotile cilia" syndrome. Eur Arch Otorhinolaryngol (1990) 0.85

Hydin seek: finding a function in ciliary motility. J Cell Biol (2007) 0.84

Isomerism of the right atrial appendages: clinical, anatomical, and microscopic study of a long-surviving case with asplenia and ciliary abnormalities. Clin Anat (2003) 0.82