Published in Nat Rev Neurosci on July 10, 2013
Primary cilia in neurodevelopmental disorders. Nat Rev Neurol (2013) 1.14
A dual role for planar cell polarity genes in ciliated cells. Proc Natl Acad Sci U S A (2014) 1.11
Loss of Dishevelleds disrupts planar polarity in ependymal motile cilia and results in hydrocephalus. Neuron (2014) 0.99
Wnt-Frizzled/Planar Cell Polarity Signaling: Cellular Orientation by Facing the Wind (Wnt). Annu Rev Cell Dev Biol (2015) 0.98
Regulation of neuronal migration by Dchs1-Fat4 planar cell polarity. Curr Biol (2014) 0.87
Spatial and temporal aspects of Wnt signaling and planar cell polarity during vertebrate embryonic development. Semin Cell Dev Biol (2015) 0.87
The Wnt adaptor protein ATP6AP2 regulates multiple stages of adult hippocampal neurogenesis. J Neurosci (2015) 0.86
Genetic evidence that Celsr3 and Celsr2, together with Fzd3, regulate forebrain wiring in a Vangl-independent manner. Proc Natl Acad Sci U S A (2014) 0.85
Fat1 interacts with Fat4 to regulate neural tube closure, neural progenitor proliferation and apical constriction during mouse brain development. Development (2015) 0.84
Classification, clinical features, and genetics of neural tube defects. Saudi Med J (2014) 0.84
Centriole positioning in epithelial cells and its intimate relationship with planar cell polarity. Bioessays (2016) 0.83
Positioning of centrioles is a conserved readout of Frizzled planar cell polarity signalling. Nat Commun (2016) 0.82
Vangl2 cooperates with Rab11 and Myosin V to regulate apical constriction during vertebrate gastrulation. Development (2014) 0.80
The involvement of PCP proteins in radial cell intercalations during Xenopus embryonic development. Dev Biol (2015) 0.80
Adhesion G protein-coupled receptors in nervous system development and disease. Nat Rev Neurosci (2016) 0.79
Cerebellar Transcriptome Profiles of ATXN1 Transgenic Mice Reveal SCA1 Disease Progression and Protection Pathways. Neuron (2016) 0.79
PCP Signaling between Migrating Neurons and their Planar-Polarized Neuroepithelial Environment Controls Filopodial Dynamics and Directional Migration. PLoS Genet (2016) 0.78
Reciprocal and dynamic polarization of planar cell polarity core components and myosin. Elife (2015) 0.78
Methods for studying planar cell polarity. Methods (2014) 0.78
Planar Cell Polarity (PCP) Protein Vangl2 Regulates Ectoplasmic Specialization Dynamics via Its Effects on Actin Microfilaments in the Testes of Male Rats. Endocrinology (2016) 0.77
Atmin mediates kidney morphogenesis by modulating Wnt signaling. Hum Mol Genet (2014) 0.77
Feedback regulation of apical progenitor fate by immature neurons through Wnt7-Celsr3-Fzd3 signalling. Nat Commun (2016) 0.76
Celsr3 and Fzd3 Organize a Pioneer Neuron Scaffold to Steer Growing Thalamocortical Axons. Cereb Cortex (2016) 0.76
Planar cell polarity in moving cells: think globally, act locally. Development (2017) 0.75
A Farnesyltransferase Acts to Inhibit Ectopic Neurite Formation in C. elegans. PLoS One (2016) 0.75
Planar cell polarity (PCP) proteins and spermatogenesis. Semin Cell Dev Biol (2016) 0.75
Localization of Core Planar Cell Polarity Proteins, PRICKLEs, in Ameloblasts of Rat Incisors: Possible Regulation of Enamel Rod Decussation. Acta Histochem Cytochem (2015) 0.75
Kif26b controls endothelial cell polarity through the Dishevelled/Daam1-dependent planar cell polarity-signaling pathway. Mol Biol Cell (2016) 0.75
Does cell polarity matter during spermatogenesis? Spermatogenesis (2016) 0.75
Hypomorphic Recessive Variants in SUFU Impair the Sonic Hedgehog Pathway and Cause Joubert Syndrome with Cranio-facial and Skeletal Defects. Am J Hum Genet (2017) 0.75
Loss of p73 in ependymal cells during the perinatal period leads to aqueductal stenosis. Sci Rep (2017) 0.75
Molecular mechanisms of axon guidance. Science (2002) 6.49
Exosomes: endosomal-derived vesicles shipping extracellular messages. Curr Opin Cell Biol (2004) 5.71
Silberblick/Wnt11 mediates convergent extension movements during zebrafish gastrulation. Nature (2000) 5.52
Vascular development in the retina and inner ear: control by Norrin and Frizzled-4, a high-affinity ligand-receptor pair. Cell (2004) 5.04
Dishevelled controls cell polarity during Xenopus gastrulation. Nature (2000) 4.91
Disruption of Bardet-Biedl syndrome ciliary proteins perturbs planar cell polarity in vertebrates. Nat Genet (2005) 4.76
Differential recruitment of Dishevelled provides signaling specificity in the planar cell polarity and Wingless signaling pathways. Genes Dev (1998) 4.51
Loss of Fat4 disrupts PCP signaling and oriented cell division and leads to cystic kidney disease. Nat Genet (2008) 4.28
Wnt/Frizzled activation of Rho regulates vertebrate gastrulation and requires a novel Formin homology protein Daam1. Cell (2001) 4.22
Anterior-posterior guidance of commissural axons by Wnt-frizzled signaling. Science (2003) 4.18
Flamingo, a seven-pass transmembrane cadherin, regulates planar cell polarity under the control of Frizzled. Cell (1999) 4.07
Xwnt11 is a target of Xenopus Brachyury: regulation of gastrulation movements via Dishevelled, but not through the canonical Wnt pathway. Development (2000) 4.06
Ciliogenesis defects in embryos lacking inturned or fuzzy function are associated with failure of planar cell polarity and Hedgehog signaling. Nat Genet (2006) 3.97
Dishevelled controls apical docking and planar polarization of basal bodies in ciliated epithelial cells. Nat Genet (2008) 3.84
Planar cell polarity signalling couples cell division and morphogenesis during neurulation. Nature (2006) 3.80
Tissue/planar cell polarity in vertebrates: new insights and new questions. Development (2007) 3.66
Mutations in VANGL1 associated with neural-tube defects. N Engl J Med (2007) 3.58
Cell flow reorients the axis of planar polarity in the wing epithelium of Drosophila. Cell (2010) 3.57
Zebrafish trilobite identifies new roles for Strabismus in gastrulation and neuronal movements. Nat Cell Biol (2002) 3.49
Ltap, a mammalian homolog of Drosophila Strabismus/Van Gogh, is altered in the mouse neural tube mutant Loop-tail. Nat Genet (2001) 3.47
Mathematical modeling of planar cell polarity to understand domineering nonautonomy. Science (2005) 3.42
The role of Frizzled3 and Frizzled6 in neural tube closure and in the planar polarity of inner-ear sensory hair cells. J Neurosci (2006) 3.36
Mutation of Celsr1 disrupts planar polarity of inner ear hair cells and causes severe neural tube defects in the mouse. Curr Biol (2003) 3.31
Planar cell polarity signalling controls cell division orientation during zebrafish gastrulation. Nature (2004) 3.29
The role of RhoA in tissue polarity and Frizzled signalling. Nature (1997) 3.22
Planar signaling and morphogenesis in Drosophila. Dev Cell (2002) 3.12
Planar cell polarization: an emerging model points in the right direction. Annu Rev Cell Dev Biol (2005) 3.10
PTK7/CCK-4 is a novel regulator of planar cell polarity in vertebrates. Nature (2004) 3.10
An incredible decade for the primary cilium: a look at a once-forgotten organelle. Am J Physiol Renal Physiol (2005) 3.07
Planar polarization in embryonic epidermis orchestrates global asymmetric morphogenesis of hair follicles. Nat Cell Biol (2008) 3.07
Directional non-cell autonomy and the transmission of polarity information by the frizzled gene of Drosophila. Nature (1987) 2.99
Dishevelled genes mediate a conserved mammalian PCP pathway to regulate convergent extension during neurulation. Development (2006) 2.96
Principles of planar polarity in animal development. Development (2011) 2.94
Planar cell polarity: one or two pathways? Nat Rev Genet (2007) 2.90
A p53-dependent mechanism underlies macrocytic anemia in a mouse model of human 5q- syndrome. Nat Med (2009) 2.89
Tissue polarity genes of Drosophila regulate the subcellular location for prehair initiation in pupal wing cells. J Cell Biol (1993) 2.80
Dishevelled 2 is essential for cardiac outflow tract development, somite segmentation and neural tube closure. Development (2002) 2.71
Coupling between hydrodynamic forces and planar cell polarity orients mammalian motile cilia. Nat Cell Biol (2010) 2.67
Dysfunction of axonemal dynein heavy chain Mdnah5 inhibits ependymal flow and reveals a novel mechanism for hydrocephalus formation. Hum Mol Genet (2004) 2.63
Recurrent somatic mutation of FAT1 in multiple human cancers leads to aberrant Wnt activation. Nat Genet (2013) 2.59
A homozygous mutation in human PRICKLE1 causes an autosomal-recessive progressive myoclonus epilepsy-ataxia syndrome. Am J Hum Genet (2008) 2.58
Frizzled6 controls hair patterning in mice. Proc Natl Acad Sci U S A (2004) 2.54
Neural tube closure requires Dishevelled-dependent convergent extension of the midline. Development (2002) 2.52
Two separate molecular systems, Dachsous/Fat and Starry night/Frizzled, act independently to confer planar cell polarity. Development (2006) 2.50
Argosomes: a potential vehicle for the spread of morphogens through epithelia. Cell (2001) 2.48
Polarized transport of Frizzled along the planar microtubule arrays in Drosophila wing epithelium. Dev Cell (2006) 2.47
Convergent extension, planar-cell-polarity signalling and initiation of mouse neural tube closure. Development (2007) 2.45
A positive feedback mechanism governs the polarity and motion of motile cilia. Nature (2007) 2.44
Dachs: an unconventional myosin that functions downstream of Fat to regulate growth, affinity and gene expression in Drosophila. Development (2006) 2.43
Mechanical control of morphogenesis by Fat/Dachsous/Four-jointed planar cell polarity pathway. Science (2012) 2.39
Dysfunctional cilia lead to altered ependyma and choroid plexus function, and result in the formation of hydrocephalus. Development (2005) 2.36
Severe neural tube defects in the loop-tail mouse result from mutation of Lpp1, a novel gene involved in floor plate specification. Hum Mol Genet (2001) 2.28
Four-jointed is a Golgi kinase that phosphorylates a subset of cadherin domains. Science (2008) 2.28
Prickle 1 regulates cell movements during gastrulation and neuronal migration in zebrafish. Development (2003) 2.26
Planar cell polarity breaks bilateral symmetry by controlling ciliary positioning. Nature (2010) 2.23
Van Gogh: a new Drosophila tissue polarity gene. Genetics (1998) 2.23
Lack of cadherins Celsr2 and Celsr3 impairs ependymal ciliogenesis, leading to fatal hydrocephalus. Nat Neurosci (2010) 2.18
Strabismus, a novel gene that regulates tissue polarity and cell fate decisions in Drosophila. Development (1998) 2.14
The Drosophila tissue polarity gene starry night encodes a member of the protocadherin family. Development (1999) 2.12
To beat or not to beat: roles of cilia in development and disease. Hum Mol Genet (2003) 2.11
The TGF beta homolog dpp and the segment polarity gene hedgehog are required for propagation of a morphogenetic wave in the Drosophila retina. Cell (1993) 2.08
The ankyrin repeat protein Diego mediates Frizzled-dependent planar polarization. Dev Cell (2001) 2.08
Mutations in Hydin impair ciliary motility in mice. J Cell Biol (2008) 2.06
Control of dendritic field formation in Drosophila: the roles of flamingo and competition between homologous neurons. Neuron (2000) 2.06
Protocadherin Celsr3 is crucial in axonal tract development. Nat Neurosci (2005) 2.01
Planar cell polarity links axes of spatial dynamics in neural-tube closure. Cell (2012) 1.98
Frizzled regulates localization of cell-fate determinants and mitotic spindle rotation during asymmetric cell division. Nat Cell Biol (2001) 1.96
Strange as it may seem: the many links between Wnt signaling, planar cell polarity, and cilia. Genes Dev (2011) 1.94
The PCP pathway instructs the planar orientation of ciliated cells in the Xenopus larval skin. Curr Biol (2009) 1.87
Cilia organize ependymal planar polarity. J Neurosci (2010) 1.80
Sec24b selectively sorts Vangl2 to regulate planar cell polarity during neural tube closure. Nat Cell Biol (2009) 1.80
Diego interacts with Prickle and Strabismus/Van Gogh to localize planar cell polarity complexes. Development (2004) 1.80
Planar cell polarity and the developmental control of cell behavior in vertebrate embryos. Annu Rev Cell Dev Biol (2012) 1.77
Early forebrain wiring: genetic dissection using conditional Celsr3 mutant mice. Science (2008) 1.76
Mice lacking the giant protocadherin mFAT1 exhibit renal slit junction abnormalities and a partially penetrant cyclopia and anophthalmia phenotype. Mol Cell Biol (2003) 1.76
Phosphorylation of the tumor suppressor fat is regulated by its ligand Dachsous and the kinase discs overgrown. Curr Biol (2009) 1.74
Patterning and axon guidance of cranial motor neurons. Nat Rev Neurosci (2007) 1.73
Characterization of a Dchs1 mutant mouse reveals requirements for Dchs1-Fat4 signaling during mammalian development. Development (2011) 1.71
The stumpy gene is required for mammalian ciliogenesis. Proc Natl Acad Sci U S A (2008) 1.66
Vertebrate segmentation: from cyclic gene networks to scoliosis. Cell (2011) 1.65
Planar cell polarity: coordinating morphogenetic cell behaviors with embryonic polarity. Dev Cell (2011) 1.64
Cilia orientation and the fluid mechanics of development. Curr Opin Cell Biol (2008) 1.62
Planar polarity specification through asymmetric subcellular localization of Fat and Dachsous. Curr Biol (2012) 1.61
Microtubules enable the planar cell polarity of airway cilia. Curr Biol (2012) 1.59
Distinct roles for the actin and microtubule cytoskeletons in the morphogenesis of epidermal hairs during wing development in Drosophila. Mech Dev (1998) 1.59
Mechanism of activation of the Formin protein Daam1. Proc Natl Acad Sci U S A (2007) 1.58
The protocadherin Flamingo is required for axon target selection in the Drosophila visual system. Nat Neurosci (2003) 1.58
The cadherin Flamingo mediates level-dependent interactions that guide photoreceptor target choice in Drosophila. Neuron (2008) 1.57
Wnt/planar cell polarity signaling controls the anterior-posterior organization of monoaminergic axons in the brainstem. J Neurosci (2010) 1.57
Fifteen formins for an actin filament: a molecular view on the regulation of human formins. Biochim Biophys Acta (2010) 1.56
Coordinated ciliary beating requires Odf2-mediated polarization of basal bodies via basal feet. Cell (2012) 1.56
Vangl2 promotes Wnt/planar cell polarity-like signaling by antagonizing Dvl1-mediated feedback inhibition in growth cone guidance. Dev Cell (2011) 1.56
The development of cortical connections. Eur J Neurosci (2006) 1.52
Development of the vertebrate central nervous system: formation of the neural tube. Prenat Diagn (2009) 1.49
Flamingo regulates R8 axon-axon and axon-target interactions in the Drosophila visual system. Curr Biol (2003) 1.49
Propagation of Dachsous-Fat planar cell polarity. Curr Biol (2012) 1.49
Turning heads: development of vertebrate branchiomotor neurons. Dev Dyn (2004) 1.46
Opposing roles in neurite growth control by two seven-pass transmembrane cadherins. Nat Neurosci (2007) 1.44
Regulation of dendritic maintenance and growth by a mammalian 7-pass transmembrane cadherin. Dev Cell (2004) 1.43
The Fz-Dsh planar cell polarity pathway induces oriented cell division via Mud/NuMA in Drosophila and zebrafish. Dev Cell (2010) 1.42
Reelin and brain development. Nat Rev Neurosci (2003) 3.97
Novel markers reveal subpopulations of subplate neurons in the murine cerebral cortex. Cereb Cortex (2008) 1.67
Reelin signals through phosphatidylinositol 3-kinase and Akt to control cortical development and through mTor to regulate dendritic growth. Mol Cell Biol (2007) 1.65
Phosphatidylinositol 3-kinase interacts with the adaptor protein Dab1 in response to Reelin signaling and is required for normal cortical lamination. J Biol Chem (2003) 1.63
The development of cortical connections. Eur J Neurosci (2006) 1.52
The central fragment of Reelin, generated by proteolytic processing in vivo, is critical to its function during cortical plate development. J Neurosci (2004) 1.42
Expression of planar cell polarity genes during development of the mouse CNS. Eur J Neurosci (2006) 1.41
Processing of Reelin by embryonic neurons is important for function in tissue but not in dissociated cultured neurons. J Neurosci (2007) 1.35
Atypical cadherins Celsr1-3 differentially regulate migration of facial branchiomotor neurons in mice. J Neurosci (2010) 1.25
Planar cell polarity cadherin Celsr1 regulates skin hair patterning in the mouse. J Invest Dermatol (2009) 1.19
Recent progress in understanding the role of Reelin in radial neuronal migration, with specific emphasis on the dentate gyrus. Eur J Neurosci (2006) 1.18
Planar cell polarity genes control the connectivity of enteric neurons. J Clin Invest (2013) 1.03
Inhibition of SRC family kinases and non-classical protein kinases C induce a reeler-like malformation of cortical plate development. J Neurosci (2003) 1.02
Gene expression analysis of the embryonic subplate. Cereb Cortex (2011) 0.98
Planar cell polarity signaling in neural development. Curr Opin Neurobiol (2010) 0.96
The reelin signaling pathway: some recent developments. Cereb Cortex (2003) 0.96
Characterization of the various forms of the Reelin protein in the cerebrospinal fluid of normal subjects and in neurological diseases. Neurobiol Dis (2004) 0.93
Celsr1-3 cadherins in PCP and brain development. Curr Top Dev Biol (2012) 0.85
DeltaNp73 transcription factors modulate cell survival and tumor development. Cell Cycle (2010) 0.85
Identification of small molecules that interfere with radial neuronal migration and early cortical plate development. Cereb Cortex (2006) 0.81
Identification of a novel brain-specific and Reelin-regulated gene that encodes a protein colocalized with synapsin. Eur J Neurosci (2004) 0.80
Atypical cadherins Celsr1-3 and planar cell polarity in vertebrates. Prog Mol Biol Transl Sci (2013) 0.79
The atypical cadherin Celsr3 regulates the development of the axonal blueprint. Novartis Found Symp (2007) 0.78
New functions and signaling mechanisms for the class of adhesion G protein-coupled receptors. Ann N Y Acad Sci (2014) 0.78
p73 and p63: Estranged relatives? Cell Cycle (2011) 0.77
[Role of the cadherin Celsr3 in the connectivity of the cerebral cortex]. Med Sci (Paris) (2008) 0.75
Role of p73 in Alzheimer disease: lack of association in mouse models or in human cohorts. Mol Neurodegener (2013) 0.75
Foreword to reviews on molecular and cellular basis of cortical development (CONCORDE). Eur J Neurosci (2006) 0.75