Published in Hum Mol Genet on January 17, 2008
Non-coding RNAs in human disease. Nat Rev Genet (2011) 11.40
Noncoding RNA in development. Mamm Genome (2008) 3.42
Implication of snoRNA U50 in human breast cancer. J Genet Genomics (2009) 1.80
Next-generation sequencing reveals novel differentially regulated mRNAs, lncRNAs, miRNAs, sdRNAs and a piRNA in pancreatic cancer. Mol Cancer (2015) 1.75
Small nucleolar RNA signatures as biomarkers for non-small-cell lung cancer. Mol Cancer (2010) 1.56
Small nucleolar RNA 42 acts as an oncogene in lung tumorigenesis. Oncogene (2011) 1.54
Are snoRNAs and snoRNA host genes new players in cancer? Nat Rev Cancer (2012) 1.44
Novel classes of non-coding RNAs and cancer. J Transl Med (2012) 1.35
Non-coding RNAs: a key to future personalized molecular therapy? Genome Med (2010) 1.29
Loss of function of the tumor suppressor DKC1 perturbs p27 translation control and contributes to pituitary tumorigenesis. Cancer Res (2010) 1.24
Processing of snoRNAs as a new source of regulatory non-coding RNAs: snoRNA fragments form a new class of functional RNAs. Bioessays (2012) 1.22
Small nucleolar RNAs in cancer. Biochim Biophys Acta (2012) 1.11
Loss of ribosomal RNA modification causes developmental defects in zebrafish. Nucleic Acids Res (2011) 1.02
Growth arrest-specific transcript 5 associated snoRNA levels are related to p53 expression and DNA damage in colorectal cancer. PLoS One (2014) 0.96
Partial methylation at Am100 in 18S rRNA of baker's yeast reveals ribosome heterogeneity on the level of eukaryotic rRNA modification. PLoS One (2014) 0.96
Quantitative analysis of rRNA modifications using stable isotope labeling and mass spectrometry. J Am Chem Soc (2014) 0.96
SnoRNAs from the filamentous fungus Neurospora crassa: structural, functional and evolutionary insights. BMC Genomics (2009) 0.96
CpG island hypermethylation-associated silencing of small nucleolar RNAs in human cancer. RNA Biol (2012) 0.92
Noncoding RNAs in cancer and cancer stem cells. Chin J Cancer (2013) 0.92
The dark matter of the cancer genome: aberrations in regulatory elements, untranslated regions, splice sites, non-coding RNA and synonymous mutations. EMBO Mol Med (2016) 0.91
Genomic analysis of high-risk smoldering multiple myeloma. Haematologica (2012) 0.90
The non-coding transcriptome as a dynamic regulator of cancer metastasis. Cancer Metastasis Rev (2014) 0.89
Transcriptome analysis reveals molecular profiles associated with evolving steps of monoclonal gammopathies. Haematologica (2014) 0.89
ATBF1 inhibits estrogen receptor (ER) function by selectively competing with AIB1 for binding to the ER in ER-positive breast cancer cells. J Biol Chem (2010) 0.89
The noncoding RNAs SNORD50A and SNORD50B bind K-Ras and are recurrently deleted in human cancer. Nat Genet (2015) 0.87
Clinical significance of SNORA42 as an oncogene and a prognostic biomarker in colorectal cancer. Gut (2015) 0.86
Small nucleolar RNA 113-1 suppresses tumorigenesis in hepatocellular carcinoma. Mol Cancer (2014) 0.86
Estrogen up-regulates ATBF1 transcription but causes its protein degradation in estrogen receptor-alpha-positive breast cancer cells. J Biol Chem (2011) 0.86
Oestrogen causes ATBF1 protein degradation through the oestrogen-responsive E3 ubiquitin ligase EFP. Biochem J (2012) 0.86
C/D-box snoRNA-derived RNA production is associated with malignant transformation and metastatic progression in prostate cancer. Oncotarget (2015) 0.86
Exposure of Human Prostaspheres to Bisphenol A Epigenetically Regulates SNORD Family Noncoding RNAs via Histone Modification. Endocrinology (2015) 0.85
Long non-coding RNA SNHG5 suppresses gastric cancer progression by trapping MTA2 in the cytosol. Oncogene (2016) 0.85
Regulatory role of small nucleolar RNAs in human diseases. Biomed Res Int (2015) 0.85
Analysis of small nucleolar RNAs in sputum for lung cancer diagnosis. Oncotarget (2016) 0.84
Dual function of C/D box small nucleolar RNAs in rRNA modification and alternative pre-mRNA splicing. Proc Natl Acad Sci U S A (2016) 0.84
SNORD76, a box C/D snoRNA, acts as a tumor suppressor in glioblastoma. Sci Rep (2015) 0.83
Regulation of snoRNAs in cancer: close encounters with interferon. J Interferon Cytokine Res (2013) 0.83
Human 45,X fibroblast transcriptome reveals distinct differentially expressed genes including long noncoding RNAs potentially associated with the pathophysiology of Turner syndrome. PLoS One (2014) 0.82
Small nucleolar RNA 78 promotes the tumorigenesis in non-small cell lung cancer. J Exp Clin Cancer Res (2015) 0.81
Regulatory Roles of Non-Coding RNAs in Colorectal Cancer. Int J Mol Sci (2015) 0.79
SnoRNA U50 levels are regulated by cell proliferation and rRNA transcription. Int J Mol Sci (2013) 0.79
Role of ERRF, a novel ER-related nuclear factor, in the growth control of ER-positive human breast cancer cells. Am J Pathol (2012) 0.78
Functional and Structural Characterization of FAU Gene/Protein from Marine Sponge Suberites domuncula. Mar Drugs (2015) 0.78
snoRNAs are a novel class of biologically relevant Myc targets. BMC Biol (2015) 0.78
SNHG5 promotes colorectal cancer cell survival by counteracting STAU1-mediated mRNA destabilization. Nat Commun (2016) 0.78
The non-coding oncogene: a case of missing DNA evidence? Front Genet (2012) 0.78
Small non-coding RNA biomarkers in sputum for lung cancer diagnosis. Mol Cancer (2016) 0.77
Generation of a mouse model with down-regulated U50 snoRNA (SNORD50) expression and its organ-specific phenotypic modulation. PLoS One (2013) 0.77
Noncoding RNAs in endocrine malignancy. Oncologist (2014) 0.76
Strong cis-acting expression quantitative trait loci for the genes encoding SNHG5 and PEX6. Medicine (Baltimore) (2016) 0.75
The human box C/D snoRNAs U3 and U8 are required for pre-rRNA processing and tumorigenesis. Oncotarget (2016) 0.75
Rpl13a small nucleolar RNAs regulate systemic glucose metabolism. J Clin Invest (2016) 0.75
High-grade glioma in very young children: a rare and particular patient population. Oncotarget (2017) 0.75
Integrated analysis of the prostate cancer small-nucleolar transcriptome reveals SNORA55 as a driver of prostate cancer progression. Mol Oncol (2015) 0.75
Human snoRNA-93 is processed into a microRNA-like RNA that promotes breast cancer cell invasion. NPJ Breast Cancer (2017) 0.75
PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer. Science (1997) 29.34
A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera. Nature (2005) 18.43
Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis. Cancer Cell (2005) 17.41
Small nucleolar RNAs: an abundant group of noncoding RNAs with diverse cellular functions. Cell (2002) 6.62
Genes specifically expressed at growth arrest of mammalian cells. Cell (1988) 5.61
The American Cancer Society Cancer Prevention Study II Nutrition Cohort: rationale, study design, and baseline characteristics. Cancer (2002) 4.88
The snoRNA HBII-52 regulates alternative splicing of the serotonin receptor 2C. Science (2005) 4.54
Identification of brain-specific and imprinted small nucleolar RNA genes exhibiting an unusual genomic organization. Proc Natl Acad Sci U S A (2000) 4.54
Small regulatory RNAs in mammals. Hum Mol Genet (2005) 4.15
AAV vector integration sites in mouse hepatocellular carcinoma. Science (2007) 3.73
High grade prostatic intraepithelial neoplasia (HGPIN) and prostatic adenocarcinoma between the ages of 20-69: an autopsy study of 249 cases. In Vivo (1995) 3.25
Classification of gas5 as a multi-small-nucleolar-RNA (snoRNA) host gene and a member of the 5'-terminal oligopyrimidine gene family reveals common features of snoRNA host genes. Mol Cell Biol (1998) 3.08
DNA copy number losses in human neoplasms. Am J Pathol (1999) 2.73
Frequent somatic mutations of the transcription factor ATBF1 in human prostate cancer. Nat Genet (2005) 2.08
Tumorigenicity in human melanoma cell lines controlled by introduction of human chromosome 6. Science (1990) 2.07
FOXO1A is a candidate for the 13q14 tumor suppressor gene inhibiting androgen receptor signaling in prostate cancer. Cancer Res (2006) 2.03
Screening for prostate cancer: estimating the magnitude of overdetection. CMAJ (1998) 1.77
Chromosomal deletions and tumor suppressor genes in prostate cancer. Cancer Metastasis Rev (2001) 1.62
Microcell-mediated transfer of chromosome 6 into metastatic human C8161 melanoma cells suppresses metastasis but does not inhibit tumorigenicity. Oncogene (1994) 1.35
Early detection of prostate cancer. Hum Pathol (1992) 1.34
RNA interference of ecto-5'-nucleotidase (CD73) inhibits human breast cancer cell growth and invasion. Clin Exp Metastasis (2007) 1.29
BiP internal ribosomal entry site activity is controlled by heat-induced interaction of NSAP1. Mol Cell Biol (2006) 1.25
Genetics and etiology of human cancer. Adv Hum Genet (1977) 1.19
Intronic U50 small-nucleolar-RNA (snoRNA) host gene of no protein-coding potential is mapped at the chromosome breakpoint t(3;6)(q27;q15) of human B-cell lymphoma. Genes Cells (2000) 1.17
A defined chromosome 6q fragment (at D6S310) harbors a putative tumor suppressor gene for breast cancer. Oncogene (1996) 1.12
Deletion of a small consensus region at 6q15, including the MAP3K7 gene, is significantly associated with high-grade prostate cancers. Clin Cancer Res (2007) 1.10
Differential expression of human 5S snoRNA genes. Biochem Biophys Res Commun (2002) 1.07
A human melanoma metastasis-suppressor locus maps to 6q16.3-q23. Int J Cancer (2000) 1.01
Screening for prostate cancer. Eur J Cancer (2005) 1.01
A prospective study of XRCC1 (X-ray cross-complementing group 1) polymorphisms and breast cancer risk. Breast Cancer Res (2005) 1.00
Microsatellite instability and mismatch repair target gene mutations in cell lines and xenografts of prostate cancer. Prostate (2006) 0.98
A gene on 6q 14-21 restores senescence to immortal ovarian tumor cells. Oncogene (1996) 0.95
Mapping of 22 new ESTs around a tumor suppressor gene and a senescence gene at 6q16-->q21. Cytogenet Cell Genet (1997) 0.79
Overweight, obesity, and mortality from cancer in a prospectively studied cohort of U.S. adults. N Engl J Med (2003) 35.39
Circulating microRNAs as stable blood-based markers for cancer detection. Proc Natl Acad Sci U S A (2008) 33.65
Lung cancer, cardiopulmonary mortality, and long-term exposure to fine particulate air pollution. JAMA (2002) 28.72
A genome-wide association study identifies alleles in FGFR2 associated with risk of sporadic postmenopausal breast cancer. Nat Genet (2007) 22.96
Genome-wide association study of prostate cancer identifies a second risk locus at 8q24. Nat Genet (2007) 21.18
Multiple loci identified in a genome-wide association study of prostate cancer. Nat Genet (2008) 17.65
Cardiovascular mortality and long-term exposure to particulate air pollution: epidemiological evidence of general pathophysiological pathways of disease. Circulation (2003) 12.78
Structure of the novel ternary hydrides Li4Tt2D (Tt=Si and Ge). Acta Crystallogr B (2007) 10.58
Spatial analysis of air pollution and mortality in Los Angeles. Epidemiology (2005) 8.64
A multistage genome-wide association study in breast cancer identifies two new risk alleles at 1p11.2 and 14q24.1 (RAD51L1). Nat Genet (2009) 8.39
MicroRNA expression profiling in prostate cancer. Cancer Res (2007) 8.04
Newly discovered breast cancer susceptibility loci on 3p24 and 17q23.2. Nat Genet (2009) 7.30
Ligand-independent androgen receptor variants derived from splicing of cryptic exons signify hormone-refractory prostate cancer. Cancer Res (2009) 7.11
Splicing of a novel androgen receptor exon generates a constitutively active androgen receptor that mediates prostate cancer therapy resistance. Cancer Res (2008) 6.33
Extended follow-up and spatial analysis of the American Cancer Society study linking particulate air pollution and mortality. Res Rep Health Eff Inst (2009) 5.92
Castration resistance in human prostate cancer is conferred by a frequently occurring androgen receptor splice variant. J Clin Invest (2010) 5.77
Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array. Nat Genet (2013) 5.58
Diabetes mellitus as a predictor of cancer mortality in a large cohort of US adults. Am J Epidemiol (2004) 5.29
The American Cancer Society Cancer Prevention Study II Nutrition Cohort: rationale, study design, and baseline characteristics. Cancer (2002) 4.88
Cardiovascular mortality and exposure to airborne fine particulate matter and cigarette smoke: shape of the exposure-response relationship. Circulation (2009) 4.84
In vivo antitumor activity of MEK and phosphatidylinositol 3-kinase inhibitors in basal-like breast cancer models. Clin Cancer Res (2009) 4.81
Resistance to CYP17A1 inhibition with abiraterone in castration-resistant prostate cancer: induction of steroidogenesis and androgen receptor splice variants. Clin Cancer Res (2011) 4.65
Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet (2012) 4.07
Prediction of erectile function following treatment for prostate cancer. JAMA (2011) 3.92
Multiple independent loci at chromosome 15q25.1 affect smoking quantity: a meta-analysis and comparison with lung cancer and COPD. PLoS Genet (2010) 3.91
Two large prospective studies of mortality among men who use snuff or chewing tobacco (United States). Cancer Causes Control (2005) 3.88
EZH2 oncogenic activity in castration-resistant prostate cancer cells is Polycomb-independent. Science (2012) 3.74
Detectable clonal mosaicism and its relationship to aging and cancer. Nat Genet (2012) 3.69
Absolute quantification by droplet digital PCR versus analog real-time PCR. Nat Methods (2013) 3.63
Monoclonal antibody targeting of N-cadherin inhibits prostate cancer growth, metastasis and castration resistance. Nat Med (2010) 3.61
Nonsteroidal antiinflammatory drug use and the risk for Parkinson's disease. Ann Neurol (2005) 3.58
Exome sequencing identifies a spectrum of mutation frequencies in advanced and lethal prostate cancers. Proc Natl Acad Sci U S A (2011) 3.54
Mortality after prostate cancer treatment with radical prostatectomy, external-beam radiation therapy, or brachytherapy in men without comorbidity. Eur Urol (2013) 3.41
Methods for pooling results of epidemiologic studies: the Pooling Project of Prospective Studies of Diet and Cancer. Am J Epidemiol (2006) 3.41
Obesity-related plasma hemodilution and PSA concentration among men with prostate cancer. JAMA (2007) 3.25
Cytoplasmic domain structures of Kir2.1 and Kir3.1 show sites for modulating gating and rectification. Nat Neurosci (2005) 3.22
Phenotypic heterogeneity of end-stage prostate carcinoma metastatic to bone. Hum Pathol (2003) 3.17
Meat consumption and risk of colorectal cancer. JAMA (2005) 3.15
A common 8q24 variant in prostate and breast cancer from a large nested case-control study. Cancer Res (2007) 3.08
Genome-wide association study of renal cell carcinoma identifies two susceptibility loci on 2p21 and 11q13.3. Nat Genet (2010) 2.96
A large cohort study of long-term daily use of adult-strength aspirin and cancer incidence. J Natl Cancer Inst (2007) 2.95
XPD and XRCC1 genetic polymorphisms are prognostic factors in advanced non-small-cell lung cancer patients treated with platinum chemotherapy. J Clin Oncol (2004) 2.93
Pesticide exposure and risk for Parkinson's disease. Ann Neurol (2006) 2.89
Androgen receptor variants occur frequently in castration resistant prostate cancer metastases. PLoS One (2011) 2.88
Morbidity and mortality after benign prostatic hyperplasia surgery: data from the American College of Surgeons national surgical quality improvement program. J Endourol (2014) 2.78
Synthesis and anticancer activity of thiosemicarbazones. Bioorg Med Chem Lett (2006) 2.78
The clinical value of somatic TP53 gene mutations in 1,794 patients with breast cancer. Clin Cancer Res (2006) 2.76
Sequencing of the sea lamprey (Petromyzon marinus) genome provides insights into vertebrate evolution. Nat Genet (2013) 2.76
Complications after robot-assisted radical cystectomy: results from the International Robotic Cystectomy Consortium. Eur Urol (2013) 2.74
Genome-wide association study of prostate cancer in men of African ancestry identifies a susceptibility locus at 17q21. Nat Genet (2011) 2.70
Effect of reclassification on the incidence of benign and malignant renal tumors. J Urol (2009) 2.67
Lung cancer death rates in lifelong nonsmokers. J Natl Cancer Inst (2006) 2.66
Nicotinic receptor gene variants influence susceptibility to heavy smoking. Cancer Epidemiol Biomarkers Prev (2008) 2.58
Genome-wide association study identifies new prostate cancer susceptibility loci. Hum Mol Genet (2011) 2.51
Variation in KLK genes, prostate-specific antigen and risk of prostate cancer. Nat Genet (2008) 2.45
Cigarette tar yields in relation to mortality from lung cancer in the cancer prevention study II prospective cohort, 1982-8. BMJ (2004) 2.42
Regulated ATP release from astrocytes through lysosome exocytosis. Nat Cell Biol (2007) 2.38
Castration-resistant prostate cancer: AUA Guideline. J Urol (2013) 2.36
Risk for nicotine dependence and lung cancer is conferred by mRNA expression levels and amino acid change in CHRNA5. Hum Mol Genet (2009) 2.35
Inducer-stimulated Fas targets activated endothelium for destruction by anti-angiogenic thrombospondin-1 and pigment epithelium-derived factor. Nat Med (2002) 2.34
Polymorphisms in the mannose binding lectin-2 gene and acute respiratory distress syndrome. Crit Care Med (2007) 2.31
Reactive oxygen generated by Nox1 triggers the angiogenic switch. Proc Natl Acad Sci U S A (2002) 2.29
Body mass index, weight change, and risk of prostate cancer in the Cancer Prevention Study II Nutrition Cohort. Cancer Epidemiol Biomarkers Prev (2006) 2.28
LuCaP 35: a new model of prostate cancer progression to androgen independence. Prostate (2003) 2.28
Weight gain, body mass index, hormone replacement therapy, and postmenopausal breast cancer in a large prospective study. Cancer Epidemiol Biomarkers Prev (2004) 2.27
The relationship between proton pump inhibitor use and longitudinal change in bone mineral density: a population-based study [corrected] from the Canadian Multicentre Osteoporosis Study (CaMos). Am J Gastroenterol (2012) 2.24
Comparison of hand assisted and standard laparoscopic radical nephroureterectomy for the management of localized transitional cell carcinoma. J Urol (2002) 2.23
Vitamin D-related genes, serum vitamin D concentrations and prostate cancer risk. Carcinogenesis (2009) 2.17
TMPRSS2:ERG fusion identifies a subgroup of prostate cancers with a favorable prognosis. Clin Cancer Res (2008) 2.16
11C-acetate PET imaging of prostate cancer: detection of recurrent disease at PSA relapse. J Nucl Med (2003) 2.16
Obesity, recreational physical activity, and risk of pancreatic cancer in a large U.S. Cohort. Cancer Epidemiol Biomarkers Prev (2005) 2.16
Zoledronic acid exhibits inhibitory effects on osteoblastic and osteolytic metastases of prostate cancer. Clin Cancer Res (2003) 2.14
Whole-genome sequencing identifies recurrent mutations in hepatocellular carcinoma. Genome Res (2013) 2.12
Frequent somatic mutations of the transcription factor ATBF1 in human prostate cancer. Nat Genet (2005) 2.08
TARP subtypes differentially and dose-dependently control synaptic AMPA receptor gating. Neuron (2007) 2.07
Tobacco use and cancer: an epidemiologic perspective for geneticists. Oncogene (2002) 2.05
Contemporary role of systematic prostate biopsies: indications, techniques, and implications for patient care. Eur Urol (2012) 2.05
Readmissions after major urologic cancer surgery. Can J Urol (2014) 2.05
FOXO1A is a candidate for the 13q14 tumor suppressor gene inhibiting androgen receptor signaling in prostate cancer. Cancer Res (2006) 2.03
To biopsy or not to biopsy: minimizing the risk of prostate needle biopsy. J Urol (2012) 2.01
Targeting p21-activated kinase 1 (PAK1) to induce apoptosis of tumor cells. Proc Natl Acad Sci U S A (2011) 2.01
Weight cycling and cancer incidence in a large prospective US cohort. Am J Epidemiol (2015) 2.00
In vivo imaging of hydrogen peroxide with chemiluminescent nanoparticles. Nat Mater (2007) 1.99
Arrowsmith two-node search interface: a tutorial on finding meaningful links between two disparate sets of articles in MEDLINE. Comput Methods Programs Biomed (2009) 1.96
Genome-wide association study of glioma and meta-analysis. Hum Genet (2012) 1.96
Inhibition of lymphocyte trafficking shields the brain against deleterious neuroinflammation after stroke. Brain (2011) 1.95
VEGF polymorphisms and survival in early-stage non-small-cell lung cancer. J Clin Oncol (2008) 1.94
Detection and isolation of prostate cancer cells from peripheral blood and bone marrow. Urology (2003) 1.94