Published in Proc Natl Acad Sci U S A on January 15, 1991
Function of conserved domains of hnRNP A1 and other hnRNP A/B proteins. EMBO J (1994) 3.35
The human splicing factor ASF/SF2 can specifically recognize pre-mRNA 5' splice sites. Proc Natl Acad Sci U S A (1994) 2.14
Direct interactions between pre-mRNA and six U2 small nuclear ribonucleoproteins during spliceosome assembly. Mol Cell Biol (1994) 2.03
The canonical GU dinucleotide at the 5' splice site is recognized by p220 of the U5 snRNP within the spliceosome. RNA (1996) 1.81
Identification of exon sequences and an exon binding protein involved in alternative RNA splicing of calcitonin/CGRP. Nucleic Acids Res (1992) 1.31
In vivo splicing of the beta tropomyosin pre-mRNA: a role for branch point and donor site competition. Mol Cell Biol (1992) 1.24
Defective splicing of mRNA from one COL1A1 allele of type I collagen in nondeforming (type I) osteogenesis imperfecta. J Clin Invest (1993) 1.06
Exon skipping by overexpression of a Drosophila heterogeneous nuclear ribonucleoprotein in vivo. Proc Natl Acad Sci U S A (1995) 1.05
An additional long-range interaction in human U1 snRNA. Nucleic Acids Res (1992) 0.84
Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Res (1983) 124.30
Pre-mRNA splicing. Annu Rev Genet (1986) 9.86
A compensatory base change in U1 snRNA suppresses a 5' splice site mutation. Cell (1986) 9.65
The U1 small nuclear RNA-protein complex selectively binds a 5' splice site in vitro. Cell (1983) 9.00
Factor required for mammalian spliceosome assembly is localized to discrete regions in the nucleus. Nature (1990) 8.79
The role of small nuclear ribonucleoprotein particles in pre-mRNA splicing. Nature (1987) 8.28
Exon definition may facilitate splice site selection in RNAs with multiple exons. Mol Cell Biol (1990) 8.17
Splicing of messenger RNA precursors. Science (1987) 7.61
A factor, U2AF, is required for U2 snRNP binding and splicing complex assembly. Cell (1988) 6.16
A protein factor, ASF, controls cell-specific alternative splicing of SV40 early pre-mRNA in vitro. Cell (1990) 5.92
The essential pre-mRNA splicing factor SF2 influences 5' splice site selection by activating proximal sites. Cell (1990) 5.67
Heterogeneous nuclear ribonucleoproteins: role in RNA splicing. Science (1986) 5.52
Identification, purification, and biochemical characterization of U2 small nuclear ribonucleoprotein auxiliary factor. Proc Natl Acad Sci U S A (1989) 5.11
A protein that specifically recognizes the 3' splice site of mammalian pre-mRNA introns is associated with a small nuclear ribonucleoprotein. Cell (1986) 4.57
Identification and purification of a 62,000-dalton protein that binds specifically to the polypyrimidine tract of introns. Genes Dev (1989) 4.53
A protein associated with small nuclear ribonucleoprotein particles recognizes the 3' splice site of premessenger RNA. Cell (1986) 4.44
RNA binding specificity of hnRNP proteins: a subset bind to the 3' end of introns. EMBO J (1988) 4.26
The effect of temperature-sensitive RNA mutants on the transcription products from cloned ribosomal protein genes of yeast. Cell (1981) 3.97
Identification of ten genes that control ribosome formation in yeast. Mol Gen Genet (1970) 3.96
Isolation of small nuclear ribonucleoproteins containing U1, U2, U4, U5, and U6 RNAs. J Biol Chem (1983) 3.65
Identification of a yeast snRNP protein and detection of snRNP-snRNP interactions. Cell (1987) 3.46
A putative ATP binding protein influences the fidelity of branchpoint recognition in yeast splicing. Cell (1990) 3.06
Splicing of yeast nuclear pre-mRNA in vitro requires a functional 40S spliceosome and several extrinsic factors. Genes Dev (1987) 3.00
Purification of the individual snRNPs U1, U2, U5 and U4/U6 from HeLa cells and characterization of their protein constituents. EMBO J (1986) 2.79
The yeast RNA gene products are essential for mRNA splicing in vitro. Cell (1986) 2.49
Two proteins crosslinked to RNA containing the adenovirus L3 poly(A) site require the AAUAAA sequence for binding. EMBO J (1988) 2.32
The C proteins of heterogeneous nuclear ribonucleoprotein complexes interact with RNA sequences downstream of polyadenylation cleavage sites. Mol Cell Biol (1988) 2.14
Preferential excision of the 5' proximal intron from mRNA precursors with two introns as mediated by the cap structure. Proc Natl Acad Sci U S A (1987) 2.04
RNA11 protein is associated with the yeast spliceosome and is localized in the periphery of the cell nucleus. Mol Cell Biol (1988) 2.01
U1-specific protein C needed for efficient complex formation of U1 snRNP with a 5' splice site. Science (1990) 1.83
U1 small nuclear ribonucleoproteins are required early during spliceosome assembly. Mol Cell Biol (1987) 1.83
Evidence for nuclear factors involved in recognition of 5' splice sites. Nucleic Acids Res (1989) 1.58
Identification and nuclear localization of yeast pre-messenger RNA processing components: RNA2 and RNA3 proteins. J Cell Biol (1986) 1.41
Recognition of 5' and 3' splice site sequences in pre-mRNA studied with a filter binding technique. J Biol Chem (1987) 1.13
UV cross-linking of polypeptides associated with 3'-terminal exons. Mol Cell Biol (1990) 0.98
Spliced segments at the 5' terminus of adenovirus 2 late mRNA. Proc Natl Acad Sci U S A (1977) 14.34
Exon definition may facilitate splice site selection in RNAs with multiple exons. Mol Cell Biol (1990) 8.17
Are U4 small nuclear ribonucleoproteins involved in polyadenylation? Nature (1984) 5.29
Transcription maps of adenovirus. Methods Enzymol (1980) 3.82
In vitro polyadenylation is stimulated by the presence of an upstream intron. Genes Dev (1990) 3.73
Gel electrophoretic isolation of splicing complexes containing U1 small nuclear ribonucleoprotein particles. Mol Cell Biol (1988) 3.56
G triplets located throughout a class of small vertebrate introns enforce intron borders and regulate splice site selection. Mol Cell Biol (1997) 3.20
U1, U2, and U4/U6 small nuclear ribonucleoproteins are required for in vitro splicing but not polyadenylation. Cell (1986) 3.07
Structure of late adenovirus 2 heterogeneous nuclear RNA. J Mol Biol (1979) 2.77
Effect of 5' splice site mutations on splicing of the preceding intron. Mol Cell Biol (1990) 2.75
Mutation of the AAUAAA polyadenylation signal depresses in vitro splicing of proximal but not distal introns. Genes Dev (1991) 2.74
Fractionation and characterization of human small nuclear ribonucleoproteins containing U1 and U2 RNAs. J Biol Chem (1983) 2.45
Architectural limits on split genes. Proc Natl Acad Sci U S A (1996) 2.29
Intron definition in splicing of small Drosophila introns. Mol Cell Biol (1994) 2.27
Dynamic relocation of transcription and splicing factors dependent upon transcriptional activity. EMBO J (1997) 2.27
Regulation of alternative polyadenylation by U1 snRNPs and SRp20. Mol Cell Biol (1998) 2.26
An intron enhancer recognized by splicing factors activates polyadenylation. Genes Dev (1996) 2.08
An intron splicing enhancer containing a G-rich repeat facilitates inclusion of a vertebrate micro-exon. RNA (1996) 2.07
Polypyrimidine tract-binding protein positively regulates inclusion of an alternative 3'-terminal exon. Mol Cell Biol (1999) 2.05
Are vertebrate exons scanned during splice-site selection? Nature (1992) 2.01
A 32-nucleotide exon-splicing enhancer regulates usage of competing 5' splice sites in a differential internal exon. Mol Cell Biol (1995) 1.92
The RNA binding protein YB-1 binds A/C-rich exon enhancers and stimulates splicing of the CD44 alternative exon v4. EMBO J (2001) 1.92
U1 small nuclear ribonucleoproteins are required early during spliceosome assembly. Mol Cell Biol (1987) 1.83
An intronic splicing enhancer binds U1 snRNPs to enhance splicing and select 5' splice sites. Mol Cell Biol (2000) 1.75
An intron enhancer containing a 5' splice site sequence in the human calcitonin/calcitonin gene-related peptide gene. Mol Cell Biol (1995) 1.67
Human U1 and U2 small nuclear ribonucleoproteins contain common and unique polypeptides. Mol Cell Biol (1982) 1.64
In vivo recognition of a vertebrate mini-exon as an exon-intron-exon unit. Mol Cell Biol (1993) 1.60
Stage-specific changes in SR splicing factors and alternative splicing in mammary tumorigenesis. Oncogene (1999) 1.60
Evidence for nuclear factors involved in recognition of 5' splice sites. Nucleic Acids Res (1989) 1.58
Participation of the C-terminal domain of RNA polymerase II in exon definition during pre-mRNA splicing. Mol Cell Biol (2000) 1.48
Control of cellular gene expression during adenovirus infection: induction and shut-off of dihydrofolate reductase gene expression by adenovirus type 2. Mol Cell Biol (1983) 1.47
Identification of exon sequences and an exon binding protein involved in alternative RNA splicing of calcitonin/CGRP. Nucleic Acids Res (1992) 1.31
A naturally arising mutation of a potential silencer of exon splicing in human immunodeficiency virus type 1 induces dominant aberrant splicing and arrests virus production. J Virol (1997) 1.31
Characterization of single-stranded viral DNA sequences present during replication of adenovirus types 2 and 5. Cell (1976) 1.30
A 5' splice site-proximal enhancer binds SF1 and activates exon bridging of a microexon. Mol Cell Biol (2000) 1.28
Evidence that a nuclear matrix protein participates in premessenger RNA splicing. Exp Cell Res (1989) 1.27
Adenovirus transcription. IV. Synthesis of viral-specific RNA in human cells infected with temperature-sensitive mutants of adenovirus 5. J Virol (1976) 1.25
Adenovirus transcription. III. Mapping of viral RNA sequences in cells productively infected by adenovirus type 5. Virology (1976) 1.23
Early events after infection of Escherichia coli by bacteriophage T5. Induction of a 5'-nucleotidase activity and excretion of free bases. J Virol (1975) 1.22
Pyrimidine tracts between the 5' splice site and branch point facilitate splicing and recognition of a small Drosophila intron. Mol Cell Biol (1997) 1.16
A role for SRp54 during intron bridging of small introns with pyrimidine tracts upstream of the branch point. Mol Cell Biol (1998) 1.13
Posttranscriptional control of DHFR gene expression during adenovirus 2 infection. J Virol (1985) 1.11
Efficient selection of 3'-terminal exons from vertebrate DNA. Nucleic Acids Res (1993) 1.10
In vitro cleavage of the simian virus 40 early polyadenylation site adjacent to a required downstream TG sequence. Mol Cell Biol (1986) 1.08
A short sequence within two purine-rich enhancers determines 5' splice site specificity. Mol Cell Biol (1998) 1.08
Nuclear-mitotic apparatus protein: a structural protein interface between the nucleoskeleton and RNA splicing. Proc Natl Acad Sci U S A (1994) 1.07
UV cross-linking of polypeptides associated with 3'-terminal exons. Mol Cell Biol (1990) 0.98
Polyadenylation precedes splicing in vitro. Gene Expr (1991) 0.98
Role of adenovirus type 2 early region 4 in the early-to-late switch during productive infection. J Virol (1986) 0.98
Calcitonin exon sequences influence alternative RNA processing. Mol Endocrinol (1990) 0.97
Validation of an in vitro RNA processing system for CT/CGRP precursor mRNA. Nucleic Acids Res (1991) 0.97
Early events after infection of Escherichia coli by bacteriophage T5. II. Control of the bacteriophage-induced 5'-nucleotidase activity. J Virol (1976) 0.91
Spliced segments at the 5' termini of adenovirus-2 late mRNA: a role for heterogeneous nuclear RNA in mammalian cells. Cold Spring Harb Symp Quant Biol (1978) 0.87
Isolation and partial characterization of bacteriophage T5 mutants deficient in the ability to induce deoxynucleoside monophosphate kinase. J Virol (1974) 0.87
Isolation and characterization of a bacteriophage T5 mutant deficient in deoxynucleoside 5'-monophosphatase activity. J Virol (1977) 0.82
Nucleotide sequence at the 5' terminus of adenovirus 2 late messenger RNA. J Biol Chem (1979) 0.79
A spliced sequence at the 5'-terminus of adenovirus late mRNA. Brookhaven Symp Biol (1979) 0.76
Spliced segments at the 5' terminus of adenovirus 2 late mRNA. 1977. Rev Med Virol (2000) 0.75