Published in J Invest Dermatol on February 07, 2008
p63 control of desmosome gene expression and adhesion is compromised in AEC syndrome. Hum Mol Genet (2012) 1.04
p63 Suppresses non-epidermal lineage markers in a bone morphogenetic protein-dependent manner via repression of Smad7. J Biol Chem (2009) 1.04
Sorting out the p63 signaling network. J Invest Dermatol (2008) 0.87
Spatiotemporal control of phosphatidylinositol 4-phosphate by Sac2 regulates endocytic recycling. J Cell Biol (2015) 0.82
A composite enhancer regulates p63 gene expression in epidermal morphogenesis and in keratinocyte differentiation by multiple mechanisms. Nucleic Acids Res (2015) 0.78
Mover is a homomeric phospho-protein present on synaptic vesicles. PLoS One (2013) 0.77
The Bioperl toolkit: Perl modules for the life sciences. Genome Res (2002) 58.63
Whole-genome shotgun assembly and analysis of the genome of Fugu rubripes. Science (2002) 20.59
Selective killing of cancer cells by a small molecule targeting the stress response to ROS. Nature (2011) 7.03
Lentiviral hematopoietic stem cell gene therapy benefits metachromatic leukodystrophy. Science (2013) 5.34
Biochemistry, cellular and molecular biology, and physiological roles of the iodothyronine selenodeiodinases. Endocr Rev (2002) 5.15
Cross-regulation between Notch and p63 in keratinocyte commitment to differentiation. Genes Dev (2006) 3.72
Biopipe: a flexible framework for protocol-based bioinformatics analysis. Genome Res (2003) 3.45
The IKMC web portal: a central point of entry to data and resources from the International Knockout Mouse Consortium. Nucleic Acids Res (2010) 3.23
Long non-coding antisense RNA controls Uchl1 translation through an embedded SINEB2 repeat. Nature (2012) 3.08
Inference of gene regulatory networks and compound mode of action from time course gene expression profiles. Bioinformatics (2006) 2.79
Notch1 is a p53 target gene involved in human keratinocyte tumor suppression through negative regulation of ROCK1/2 and MRCKalpha kinases. Genes Dev (2007) 2.61
Increased Wnt signaling triggers oncogenic conversion of human breast epithelial cells by a Notch-dependent mechanism. Proc Natl Acad Sci U S A (2006) 2.49
A small molecule that binds Hedgehog and blocks its signaling in human cells. Nat Chem Biol (2009) 2.21
Integrated genetic and epigenetic analysis identifies haplotype-specific methylation in the FTO type 2 diabetes and obesity susceptibility locus. PLoS One (2010) 1.93
EGFR signalling as a negative regulator of Notch1 gene transcription and function in proliferating keratinocytes and cancer. Nat Cell Biol (2008) 1.88
ETV6 mutations in early immature human T cell leukemias. J Exp Med (2011) 1.88
Comparative methylome analysis of benign and malignant peripheral nerve sheath tumors. Genome Res (2011) 1.60
Genome-wide signatures of convergent evolution in echolocating mammals. Nature (2013) 1.59
Type 3 iodothyronine deiodinase is highly expressed in the human uteroplacental unit and in fetal epithelium. J Clin Endocrinol Metab (2003) 1.58
The non-classical export routes: FGF1 and IL-1alpha point the way. J Cell Sci (2003) 1.57
Phylogenomic analyses elucidate the evolutionary relationships of bats. Curr Biol (2013) 1.56
Sonic hedgehog-induced type 3 deiodinase blocks thyroid hormone action enhancing proliferation of normal and malignant keratinocytes. Proc Natl Acad Sci U S A (2007) 1.54
Common variants at the MHC locus and at chromosome 16q24.1 predispose to Barrett's esophagus. Nat Genet (2012) 1.52
The impact of management on medical professionalism: a review. Sociol Health Illn (2011) 1.47
The desmosomal protein desmoglein 1 aids recovery of epidermal differentiation after acute UV light exposure. J Invest Dermatol (2014) 1.43
PRGdb: a bioinformatics platform for plant resistance gene analysis. Nucleic Acids Res (2009) 1.40
Germline CDH1 deletions in hereditary diffuse gastric cancer families. Hum Mol Genet (2009) 1.39
p63 regulates Satb1 to control tissue-specific chromatin remodeling during development of the epidermis. J Cell Biol (2011) 1.39
Social network analysis in primary care: the impact of interactions on prescribing behaviour. Health Policy (2009) 1.37
A multicassette Gateway vector set for high throughput and comparative analyses in ciona and vertebrate embryos. PLoS One (2007) 1.36
The FoxO3/type 2 deiodinase pathway is required for normal mouse myogenesis and muscle regeneration. J Clin Invest (2010) 1.35
Direct targets of the TRP63 transcription factor revealed by a combination of gene expression profiling and reverse engineering. Genome Res (2008) 1.29
Transcriptional repression of miR-34 family contributes to p63-mediated cell cycle progression in epidermal cells. J Invest Dermatol (2010) 1.29
Regulation of hematopoietic stem cell differentiation by a single ubiquitin ligase-substrate complex. Nat Immunol (2010) 1.28
The TATA-binding protein regulates maternal mRNA degradation and differential zygotic transcription in zebrafish. EMBO J (2007) 1.28
Human type 3 iodothyronine selenodeiodinase is located in the plasma membrane and undergoes rapid internalization to endosomes. J Biol Chem (2002) 1.26
CDIP, a novel pro-apoptotic gene, regulates TNFalpha-mediated apoptosis in a p53-dependent manner. EMBO J (2007) 1.25
Missense mutation in the transcription factor NKX2-5: a novel molecular event in the pathogenesis of thyroid dysgenesis. J Clin Endocrinol Metab (2006) 1.21
Dynamic regulation of the transcription initiation landscape at single nucleotide resolution during vertebrate embryogenesis. Genome Res (2013) 1.20
Deiodinases: the balance of thyroid hormone: local impact of thyroid hormone inactivation. J Endocrinol (2011) 1.20
Identification, characterization and expression analysis of a new fibrillar collagen gene, COL27A1. Matrix Biol (2003) 1.19
Concern DDR1 receptor tyrosine kinase promotes prosurvival pathway through Notch1 activation. J Biol Chem (2011) 1.18
Ubiquitination-induced conformational change within the deiodinase dimer is a switch regulating enzyme activity. Mol Cell Biol (2007) 1.17
Shuffling of cis-regulatory elements is a pervasive feature of the vertebrate lineage. Genome Biol (2006) 1.16
Copper chelation represses the vascular response to injury. Proc Natl Acad Sci U S A (2003) 1.13
An autoregulatory loop directs the tissue-specific expression of p63 through a long-range evolutionarily conserved enhancer. Mol Cell Biol (2006) 1.13
Mutant p63 causes defective expansion of ectodermal progenitor cells and impaired FGF signalling in AEC syndrome. EMBO Mol Med (2012) 1.13
Notch activation suppresses fibroblast growth factor-dependent cellular transformation. J Biol Chem (2003) 1.12
Endoplasmic reticulum-associated degradation of the human type 2 iodothyronine deiodinase (D2) is mediated via an association between mammalian UBC7 and the carboxyl region of D2. Mol Endocrinol (2003) 1.11
A 21-year-old woman with consumptive hypothyroidism due to a vascular tumor expressing type 3 iodothyronine deiodinase. J Clin Endocrinol Metab (2002) 1.10
Discovery of a potent and selective DDR1 receptor tyrosine kinase inhibitor. ACS Chem Biol (2013) 1.08
Identification of ROCK1 kinase as a critical regulator of Beclin1-mediated autophagy during metabolic stress. Nat Commun (2013) 1.08
Type 2 iodothyronine deiodinase levels are higher in slow-twitch than fast-twitch mouse skeletal muscle and are increased in hypothyroidism. Endocrinology (2010) 1.06
p63 control of desmosome gene expression and adhesion is compromised in AEC syndrome. Hum Mol Genet (2012) 1.04
p63 Suppresses non-epidermal lineage markers in a bone morphogenetic protein-dependent manner via repression of Smad7. J Biol Chem (2009) 1.04
β-Catenin regulates deiodinase levels and thyroid hormone signaling in colon cancer cells. Gastroenterology (2012) 1.04
The different cardiac expression of the type 2 iodothyronine deiodinase gene between human and rat is related to the differential response of the Dio2 genes to Nkx-2.5 and GATA-4 transcription factors. Mol Endocrinol (2003) 1.02
The intracellular translocation of the components of the fibroblast growth factor 1 release complex precedes their assembly prior to export. J Cell Biol (2002) 1.02
Requirement of the forkhead gene Foxe1, a target of sonic hedgehog signaling, in hair follicle morphogenesis. Hum Mol Genet (2004) 1.02
Exome sequence identifies RIPK4 as the Bartsocas-Papas syndrome locus. Am J Hum Genet (2011) 1.00
The UniTrap resource: tools for the biologist enabling optimized use of gene trap clones. Nucleic Acids Res (2007) 0.98
The non-transmembrane form of Delta1, but not of Jagged1, induces normal migratory behavior accompanied by fibroblast growth factor receptor 1-dependent transformation. J Biol Chem (2004) 0.98
A novel function for FOXP3 in humans: intrinsic regulation of conventional T cells. Blood (2012) 0.96
Protection from UV-induced skin carcinogenesis by genetic inhibition of the ataxia telangiectasia and Rad3-related (ATR) kinase. Proc Natl Acad Sci U S A (2011) 0.95
Promiscuity of enhancer, coding and non-coding transcription functions in ultraconserved elements. BMC Genomics (2010) 0.95
Consumptive hypothyroidism resulting from hepatic vascular tumors in an athyreotic adult. J Clin Endocrinol Metab (2011) 0.95
Insulin/IGF-1 controls epidermal morphogenesis via regulation of FoxO-mediated p63 inhibition. Dev Cell (2013) 0.95
International Research Symposium on Ankyloblepharon-Ectodermal Defects-Cleft Lip/Palate (AEC) syndrome. Am J Med Genet A (2009) 0.94
Metabolic instability of type 2 deiodinase is transferable to stable proteins independently of subcellular localization. J Biol Chem (2006) 0.94
Highly conserved elements discovered in vertebrates are present in non-syntenic loci of tunicates, act as enhancers and can be transcribed during development. Nucleic Acids Res (2013) 0.94
Fine needle cytology and flow cytometry of ectopic cervical thymoma: a case report. Acta Cytol (2010) 0.93
Embryonic stem cells as an ectodermal cellular model of human p63-related dysplasia syndromes. Biochem Biophys Res Commun (2010) 0.93
Type II iodothyronine deiodinase provides intracellular 3,5,3'-triiodothyronine to normal and regenerating mouse skeletal muscle. Am J Physiol Endocrinol Metab (2011) 0.93
A novel view of the transcriptome revealed from gene trapping in mouse embryonic stem cells. Genome Res (2007) 0.93
TAp63 is important for cardiac differentiation of embryonic stem cells and heart development. Stem Cells (2011) 0.93
Pretranslational regulation of type 2 deiodinase. Thyroid (2005) 0.93
Cell biology: Dormant and restless skin stem cells. Nature (2012) 0.91
BASC: an integrated bioinformatics system for Brassica research. Nucleic Acids Res (2006) 0.91
Transcription factor Nkx-2.5 induces sodium/iodide symporter gene expression and participates in retinoic acid- and lactation-induced transcription in mammary cells. Mol Cell Biol (2004) 0.90
Ectodysplasin regulates pattern formation in the mammalian hair coat. Genesis (2003) 0.90
Comparative analysis of the testis and ovary transcriptomes in zebrafish by combining experimental and computational tools. Comp Funct Genomics (2004) 0.90
Social Epigenetics and Equality of Opportunity. Public Health Ethics (2013) 0.89
The deiodinases and the control of intracellular thyroid hormone signaling during cellular differentiation. Biochim Biophys Acta (2012) 0.89
The C. savignyi genetic map and its integration with the reference sequence facilitates insights into chordate genome evolution. Genome Res (2008) 0.89
Characterisation and validation of insertions and deletions in 173 patient exomes. PLoS One (2012) 0.89
Sphingosine kinase 1 is a critical component of the copper-dependent FGF1 export pathway. Exp Cell Res (2007) 0.88
Role of type 3 deiodinase in cancer. Expert Opin Ther Targets (2009) 0.87
Glucocorticoid-induced tumor necrosis factor receptor is a p21Cip1/WAF1 transcriptional target conferring resistance of keratinocytes to UV light-induced apoptosis. J Biol Chem (2005) 0.87
Mixed lineage kinase 3 gene mutations in mismatch repair deficient gastrointestinal tumours. Hum Mol Genet (2009) 0.86