International Research Symposium on Ankyloblepharon-Ectodermal Defects-Cleft Lip/Palate (AEC) syndrome.

Mutant p63 causes defective expansion of ectodermal progenitor cells and impaired FGF signalling in AEC syndrome. EMBO Mol Med (2012) 1.13

Integrating animal models and in vitro tissue models to elucidate the role of desmosomal proteins in diseases. Cell Commun Adhes (2014) 0.81

A rare variant of ankyloblepharon filiforme adnatum associated with skin hypopigmentation: A case report from South India. Indian J Ophthalmol (2016) 0.75

Ankyloblepharon Filiforme Adnatum in a Newborn. AJP Rep (2014) 0.75

Ectodermal Dysplasia Showing the Clinical Overlap between Hay Wells Syndrome and Bowen Armstrong Syndrome. Iran J Pediatr (2011) 0.75

Relationships between p63 binding, DNA sequence, transcription activity, and biological function in human cells. Mol Cell (2006) 4.51

Cross-regulation between Notch and p63 in keratinocyte commitment to differentiation. Genes Dev (2006) 3.72

Hay-Wells syndrome is caused by heterozygous missense mutations in the SAM domain of p63. Hum Mol Genet (2001) 2.95

p63 induces key target genes required for epidermal morphogenesis. Proc Natl Acad Sci U S A (2007) 2.31

p63-associated disorders. Cell Cycle (2007) 2.05

Identification of TFB5, a new component of general transcription and DNA repair factor IIH. Nat Genet (2004) 1.99

The p63 gene in EEC and other syndromes. J Med Genet (2002) 1.80

The role of p63 in development and differentiation of the epidermis. J Dermatol Sci (2004) 1.37

Pattern of p63 mutations and their phenotypes--update. Am J Med Genet A (2006) 1.36

P63 alpha mutations lead to aberrant splicing of keratinocyte growth factor receptor in the Hay-Wells syndrome. J Biol Chem (2003) 1.23

Transgenic mouse models provide new insights into the role of p63 in epidermal development. Cell Cycle (2004) 1.07

DeltaNp63 knockdown mice: A mouse model for AEC syndrome. Am J Med Genet A (2009) 1.03

Spectrum of p63 mutations in a selected patient cohort affected with ankyloblepharon-ectodermal defects-cleft lip/palate syndrome (AEC). Am J Med Genet A (2009) 1.02

Dermatologic findings of ankyloblepharon-ectodermal defects-cleft lip/palate (AEC) syndrome. Am J Med Genet A (2009) 1.01

P63 deficiency: a failure of lineage commitment or stem cell maintenance? J Investig Dermatol Symp Proc (2005) 1.00

A new Perp in the lineup: linking p63 and desmosomal adhesion. Cell Cycle (2005) 0.90

AEC-associated p63 mutations lead to alternative splicing/protein stabilization of p63 and modulation of Notch signaling. Cell Cycle (2005) 0.87

Craniofacial and anthropometric phenotype in ankyloblepharon-ectodermal defects-cleft lip/palate syndrome (Hay-Wells syndrome) in a cohort of 17 patients. Am J Med Genet A (2009) 0.85

Differential PERP regulation by TP63 mutants provides insight into AEC pathogenesis. Am J Med Genet A (2009) 0.84

Skin erosions and wound healing in ankyloblepharon-ectodermal defect-cleft lip and/or palate. Arch Dermatol (2005) 0.84

Pathologic changes of skin and hair in ankyloblepharon-ectodermal defects-cleft lip/palate (AEC) syndrome. Am J Med Genet A (2009) 0.83

Ectodermal dysplasia showing clinical overlap between AEC, Rapp-Hodgkin and CHAND syndromes. Clin Exp Dermatol (2004) 0.82

Clinical lessons learned from the International Research Symposium on Ankyloblepharon-Ectodermal Defects-Cleft Lip/Palate (AEC) syndrome. Am J Med Genet A (2009) 0.81

Psychosocial functioning and quality of life in children and families affected by AEC syndrome. Am J Med Genet A (2009) 0.81

Facial clefting and oroauditory pathway manifestations in ankyloblepharon-ectodermal defects-cleft lip/palate (AEC) syndrome. Am J Med Genet A (2009) 0.81

Growth, nutritional, and gastrointestinal aspects of ankyloblepharon-ectodermal defect-cleft lip and/or palate (AEC) syndrome. Am J Med Genet A (2009) 0.77

A large intergenic noncoding RNA induced by p53 mediates global gene repression in the p53 response. Cell (2010) 12.27

Keap1-null mutation leads to postnatal lethality due to constitutive Nrf2 activation. Nat Genet (2003) 6.69

p63 Is essential for the proliferative potential of stem cells in stratified epithelia. Cell (2007) 6.50

p63 is the molecular switch for initiation of an epithelial stratification program. Genes Dev (2004) 6.40

Distinct p53 transcriptional programs dictate acute DNA-damage responses and tumor suppression. Cell (2011) 4.74

p63 and p73 are required for p53-dependent apoptosis in response to DNA damage. Nature (2002) 4.56

Relationships between p63 binding, DNA sequence, transcription activity, and biological function in human cells. Mol Cell (2006) 4.51

The role of apoptosis in cancer development and treatment response. Nat Rev Cancer (2005) 4.19

Tumor predisposition in mice mutant for p63 and p73: evidence for broader tumor suppressor functions for the p53 family. Cancer Cell (2005) 4.14

Control profiles of complex networks. Science (2014) 4.10

Ribosomal mutations cause p53-mediated dark skin and pleiotropic effects. Nat Genet (2008) 4.02

p63 protects the female germ line during meiotic arrest. Nature (2006) 3.98

Cross-regulation between Notch and p63 in keratinocyte commitment to differentiation. Genes Dev (2006) 3.72

On the shoulders of giants: p63, p73 and the rise of p53. Trends Genet (2002) 3.57

Residual embryonic cells as precursors of a Barrett's-like metaplasia. Cell (2011) 3.36

REDD1, a developmentally regulated transcriptional target of p63 and p53, links p63 to regulation of reactive oxygen species. Mol Cell (2002) 3.29

Distal airway stem cells yield alveoli in vitro and during lung regeneration following H1N1 influenza infection. Cell (2011) 3.00

Successful treatment of severe atopic dermatitis in a child and an adult with the T-cell modulator efalizumab. Arch Dermatol (2006) 3.00

Guidelines of care for acne vulgaris management. J Am Acad Dermatol (2007) 2.80

The p53QS transactivation-deficient mutant shows stress-specific apoptotic activity and induces embryonic lethality. Nat Genet (2005) 2.66

Perp is a p63-regulated gene essential for epithelial integrity. Cell (2005) 2.58

Mechanisms regulating epithelial stratification. Annu Rev Cell Dev Biol (2007) 2.47

DeltaNp63alpha and TAp63alpha regulate transcription of genes with distinct biological functions in cancer and development. Cancer Res (2003) 2.46

Apoptotic cells activate the "phoenix rising" pathway to promote wound healing and tissue regeneration. Sci Signal (2010) 2.36

p63 induces key target genes required for epidermal morphogenesis. Proc Natl Acad Sci U S A (2007) 2.31

Integration of Notch 1 and calcineurin/NFAT signaling pathways in keratinocyte growth and differentiation control. Dev Cell (2005) 2.21

IkappaB kinase-alpha acts in the epidermis to control skeletal and craniofacial morphogenesis. Nature (2004) 2.21

The threshold pattern of calcineurin-dependent gene expression is altered by loss of the endogenous inhibitor calcipressin. Nat Immunol (2003) 2.17

PhyloNet: a software package for analyzing and reconstructing reticulate evolutionary relationships. BMC Bioinformatics (2008) 2.07

Developmental context determines latency of MYC-induced tumorigenesis. PLoS Biol (2004) 2.05

Mutations in ABCA12 underlie the severe congenital skin disease harlequin ichthyosis. Am J Hum Genet (2005) 1.97

Global genomic profiling reveals an extensive p53-regulated autophagy program contributing to key p53 responses. Genes Dev (2013) 1.88

The metastasis-associated gene Prl-3 is a p53 target involved in cell-cycle regulation. Mol Cell (2008) 1.88

p53 at a glance. J Cell Sci (2010) 1.88

p63 and p73 are not required for the development and p53-dependent apoptosis of T cells. Cancer Cell (2004) 1.86

p63 regulates commitment to the prostate cell lineage. Proc Natl Acad Sci U S A (2005) 1.80

Dual roles of human BubR1, a mitotic checkpoint kinase, in the monitoring of chromosomal instability. Cancer Cell (2003) 1.78

A C-terminal inhibitory domain controls the activity of p63 by an intramolecular mechanism. Mol Cell Biol (2002) 1.73

Gain-of-function mutant p53 but not p53 deletion promotes head and neck cancer progression in response to oncogenic K-ras. J Pathol (2011) 1.72

Targeted deletion of the calcineurin inhibitor DSCR1 suppresses tumor growth. Cancer Cell (2008) 1.72

ALDH1A isozymes are markers of human melanoma stem cells and potential therapeutic targets. Stem Cells (2012) 1.70

Transcriptional regulation of bcl-2 mediated by the sonic hedgehog signaling pathway through gli-1. J Biol Chem (2003) 1.65

An unexpected role for keratin 10 end domains in susceptibility to skin cancer. J Cell Sci (2006) 1.64

An inducible mouse model for skin cancer reveals distinct roles for gain- and loss-of-function p53 mutations. J Clin Invest (2007) 1.64

Deconstructing p53 transcriptional networks in tumor suppression. Trends Cell Biol (2011) 1.62

Neuronal differentiation by TAp73 is mediated by microRNA-34a regulation of synaptic protein targets. Proc Natl Acad Sci U S A (2011) 1.58

The Grainyhead-like epithelial transactivator Get-1/Grhl3 regulates epidermal terminal differentiation and interacts functionally with LMO4. Dev Biol (2006) 1.58

Sonic hedgehog-induced type 3 deiodinase blocks thyroid hormone action enhancing proliferation of normal and malignant keratinocytes. Proc Natl Acad Sci U S A (2007) 1.54

Confounding factors in HGT detection: statistical error, coalescent effects, and multiple solutions. J Comput Biol (2007) 1.52

DeltaNp63 induces beta-catenin nuclear accumulation and signaling. Cancer Cell (2002) 1.51

p63 heterozygous mutant mice are not prone to spontaneous or chemically induced tumors. Proc Natl Acad Sci U S A (2006) 1.48

Mutations in the p53 homolog p63: allele-specific developmental syndromes in humans. Trends Mol Med (2002) 1.46

Differentiation of mouse induced pluripotent stem cells into a multipotent keratinocyte lineage. J Invest Dermatol (2010) 1.45

Loss of the desmosomal protein perp enhances the phenotypic effects of pemphigus vulgaris autoantibodies. J Invest Dermatol (2009) 1.44

DeltaNp63alpha up-regulates the Hsp70 gene in human cancer. Cancer Res (2005) 1.44

Increased sensitivity to UV radiation in mice with a p53 point mutation at Ser389. Mol Cell Biol (2004) 1.44

Inducible activation of oncogenic K-ras results in tumor formation in the oral cavity. Cancer Res (2004) 1.40

More on propranolol for hemangiomas of infancy. N Engl J Med (2008) 1.39

p63 regulates Satb1 to control tissue-specific chromatin remodeling during development of the epidermis. J Cell Biol (2011) 1.39

Genome-wide analysis of p53 under hypoxic conditions. Mol Cell Biol (2006) 1.37

The role of p63 in development and differentiation of the epidermis. J Dermatol Sci (2004) 1.37

A multicassette Gateway vector set for high throughput and comparative analyses in ciona and vertebrate embryos. PLoS One (2007) 1.36

Identification of a peptide fragment of DSCR1 that competitively inhibits calcineurin activity in vitro and in vivo. Proc Natl Acad Sci U S A (2005) 1.33

Desmosomes: new perpetrators in tumour suppression. Nat Rev Cancer (2011) 1.33

Detection of promoter hypermethylation of multiple genes in the tumor and bronchoalveolar lavage of patients with lung cancer. Clin Cancer Res (2004) 1.32

Dual role of sumoylation in the nuclear localization and transcriptional activation of NFAT1. J Biol Chem (2004) 1.31

Direct targets of the TRP63 transcription factor revealed by a combination of gene expression profiling and reverse engineering. Genome Res (2008) 1.29

Gain-of-function mutation in ADULT syndrome reveals the presence of a second transactivation domain in p63. Hum Mol Genet (2002) 1.29

Osteoblasts derived from induced pluripotent stem cells form calcified structures in scaffolds both in vitro and in vivo. Stem Cells (2011) 1.29

Transcriptional repression of miR-34 family contributes to p63-mediated cell cycle progression in epidermal cells. J Invest Dermatol (2010) 1.29

Therapeutic siRNAs for dominant genetic skin disorders including pachyonychia congenita. J Dermatol Sci (2008) 1.28

DNA damage in oocytes induces a switch of the quality control factor TAp63α from dimer to tetramer. Cell (2011) 1.25

p73 regulates maintenance of neural stem cell. Biochem Biophys Res Commun (2010) 1.25

Overexpression of AQP5, a putative oncogene, promotes cell growth and transformation. Cancer Lett (2008) 1.23

P63 alpha mutations lead to aberrant splicing of keratinocyte growth factor receptor in the Hay-Wells syndrome. J Biol Chem (2003) 1.23

Deleted in colorectal cancer is a putative conditional tumor-suppressor gene inactivated by promoter hypermethylation in head and neck squamous cell carcinoma. Cancer Res (2006) 1.22

p53 prevents progression of nevi to melanoma predominantly through cell cycle regulation. Pigment Cell Melanoma Res (2010) 1.21

Genetic heterogeneity of KID syndrome: identification of a Cx30 gene (GJB6) mutation in a patient with KID syndrome and congenital atrichia. J Invest Dermatol (2004) 1.21

Pathways connecting telomeres and p53 in senescence, apoptosis, and cancer. Biochem Biophys Res Commun (2005) 1.20

Hereditary woolly hair and keratosis pilaris. J Am Acad Dermatol (2006) 1.20

Identification, characterization and expression analysis of a new fibrillar collagen gene, COL27A1. Matrix Biol (2003) 1.19

DeltaNp63alpha levels correlate with clinical tumor response to cisplatin. Cell Cycle (2005) 1.18

Horizontal basal cells are multipotent progenitors in normal and injured adult olfactory epithelium. Stem Cells (2008) 1.16

In utero activation of K5.CrePR1 induces gene deletion. Genesis (2002) 1.14

CDC91L1 (PIG-U) is a newly discovered oncogene in human bladder cancer. Nat Med (2004) 1.14

In vivo analysis of p53 tumor suppressor function using genetically engineered mouse models. Carcinogenesis (2010) 1.14

An autoregulatory loop directs the tissue-specific expression of p63 through a long-range evolutionarily conserved enhancer. Mol Cell Biol (2006) 1.13

Mutant p63 causes defective expansion of ectodermal progenitor cells and impaired FGF signalling in AEC syndrome. EMBO Mol Med (2012) 1.13

Side population cells from human melanoma tumors reveal diverse mechanisms for chemoresistance. J Invest Dermatol (2012) 1.12

Multiple response elements and differential p53 binding control Perp expression during apoptosis. Mol Cancer Res (2003) 1.11

Perp is a mediator of p53-dependent apoptosis in diverse cell types. Curr Biol (2003) 1.11

GS2: an efficiently computable measure of GO-based similarity of gene sets. Bioinformatics (2009) 1.11

Disruption of dihydronicotinamide riboside:quinone oxidoreductase 2 (NQO2) leads to myeloid hyperplasia of bone marrow and decreased sensitivity to menadione toxicity. J Biol Chem (2002) 1.11

Keratin 6 is not essential for mammary gland development. Breast Cancer Res (2006) 1.10

Interaction and colocalization of PGP9.5 with JAB1 and p27(Kip1). Oncogene (2002) 1.10

Conflicting roles for p63 in skin development and carcinogenesis. Cell Cycle (2007) 1.10