Rev is necessary for translation but not cytoplasmic accumulation of HIV-1 vif, vpr, and env/vpu 2 RNAs.

PubWeight™: 3.06‹?› | Rank: Top 1%

🔗 View Article (PMID 1827422)

Published in Genes Dev on May 01, 1991

Authors

S J Arrigo1, I S Chen

Author Affiliations

1: Department of Microbiology, University of California, Los Angeles School of Medicine.

Articles citing this

Alternative splicing of human immunodeficiency virus type 1 mRNA modulates viral protein expression, replication, and infectivity. J Virol (1993) 3.90

Distinct RNA sequences in the gag region of human immunodeficiency virus type 1 decrease RNA stability and inhibit expression in the absence of Rev protein. J Virol (1992) 3.44

Mutational inactivation of an inhibitory sequence in human immunodeficiency virus type 1 results in Rev-independent gag expression. J Virol (1992) 3.14

Viral protein U counteracts a human host cell restriction that inhibits HIV-1 particle production. Proc Natl Acad Sci U S A (2003) 3.05

Evidence that HIV-1 Rev directly promotes the nuclear export of unspliced RNA. EMBO J (1994) 3.02

The Rev protein of human immunodeficiency virus type 1 promotes polysomal association and translation of gag/pol and vpu/env mRNAs. Mol Cell Biol (1992) 2.83

Rev and the fate of pre-mRNA in the nucleus: implications for the regulation of RNA processing in eukaryotes. Mol Cell Biol (1993) 2.79

Eukaryotic initiation factor 5A is a cellular target of the human immunodeficiency virus type 1 Rev activation domain mediating trans-activation. J Cell Biol (1993) 2.64

Identification of positive and negative splicing regulatory elements within the terminal tat-rev exon of human immunodeficiency virus type 1. Mol Cell Biol (1995) 2.55

Continuous propagation of RRE(-) and Rev(-)RRE(-) human immunodeficiency virus type 1 molecular clones containing a cis-acting element of simian retrovirus type 1 in human peripheral blood lymphocytes. J Virol (1994) 2.41

Identification and characterization of intragenic sequences which repress human immunodeficiency virus structural gene expression. J Virol (1991) 2.26

Requirement of the Pr55gag precursor for incorporation of the Vpr product into human immunodeficiency virus type 1 viral particles. J Virol (1994) 2.20

Mutagenic analysis of human immunodeficiency virus type 1 Vpr: role of a predicted N-terminal alpha-helical structure in Vpr nuclear localization and virion incorporation. J Virol (1995) 2.09

Envelope glycoprotein and CD4 independence of vpu-facilitated human immunodeficiency virus type 1 capsid export. J Virol (1992) 2.05

A Rev-independent human immunodeficiency virus type 1 (HIV-1)-based vector that exploits a codon-optimized HIV-1 gag-pol gene. J Virol (2000) 2.00

Ribozyme-mediated inhibition of HIV 1 suggests nucleolar trafficking of HIV-1 RNA. Proc Natl Acad Sci U S A (2000) 1.88

The posttranscriptional control element of the simian retrovirus type 1 forms an extensive RNA secondary structure necessary for its function. J Virol (1996) 1.85

Avian retroviral RNA element promotes unspliced RNA accumulation in the cytoplasm. J Virol (1996) 1.85

Efficient replication of human immunodeficiency virus type 1 requires a threshold level of Rev: potential implications for latency. J Virol (1992) 1.74

The human immunodeficiency virus type 1 Rev protein shuttles between the cytoplasm and nuclear compartments. Mol Cell Biol (1994) 1.67

Nuclear import, virion incorporation, and cell cycle arrest/differentiation are mediated by distinct functional domains of human immunodeficiency virus type 1 Vpr. J Virol (1997) 1.65

Splicing efficiency of human immunodeficiency virus type 1 tat RNA is determined by both a suboptimal 3' splice site and a 10 nucleotide exon splicing silencer element located within tat exon 2. Nucleic Acids Res (1997) 1.61

SR protein splicing factors interact with the Rous sarcoma virus negative regulator of splicing element. J Virol (1996) 1.49

Human immunodeficiency virus type 1 Vpr is a positive regulator of viral transcription and infectivity in primary human macrophages. J Exp Med (1998) 1.49

A conserved LXXLF sequence is the major determinant in p6gag required for the incorporation of human immunodeficiency virus type 1 Vpr. J Virol (1996) 1.47

Efficient expression of the human papillomavirus type 16 L1 protein in epithelial cells by using Rev and the Rev-responsive element of human immunodeficiency virus or the cis-acting transactivation element of simian retrovirus type 1. J Virol (1995) 1.43

PSF acts through the human immunodeficiency virus type 1 mRNA instability elements to regulate virus expression. Mol Cell Biol (2003) 1.43

trans-dominant inhibition of human immunodeficiency virus type 1 Rev occurs through formation of inactive protein complexes. J Virol (1992) 1.42

The Rev protein of human immunodeficiency virus type 1 counteracts the effect of an AU-rich negative element in the human papillomavirus type 1 late 3' untranslated region. J Virol (1995) 1.40

Human immunodeficiency virus env expression becomes Rev-independent if the env region is not defined as an intron. J Virol (1994) 1.38

Effects of translation initiation factor eIF-5A on the functioning of human T-cell leukemia virus type I Rex and human immunodeficiency virus Rev inhibited trans dominantly by a Rex mutant deficient in RNA binding. J Virol (1995) 1.33

Rev proteins of human and simian immunodeficiency virus enhance RNA encapsidation. PLoS Pathog (2007) 1.30

Mechanisms employed by retroviruses to exploit host factors for translational control of a complicated proteome. Retrovirology (2009) 1.29

The 5' RNA terminus of spleen necrosis virus contains a novel posttranscriptional control element that facilitates human immunodeficiency virus Rev/RRE-independent Gag production. J Virol (1999) 1.28

Recognition of the high affinity binding site in rev-response element RNA by the human immunodeficiency virus type-1 rev protein. Nucleic Acids Res (1992) 1.27

Human T-cell leukemia virus type 2 Rex protein increases stability and promotes nuclear to cytoplasmic transport of gag/pol and env RNAs. J Virol (1999) 1.26

Molecular biology and pathogenesis of animal lentivirus infections. Clin Microbiol Rev (1996) 1.26

p53-Independent and -dependent requirements for E1B-55K in adenovirus type 5 replication. J Virol (1999) 1.25

Mutagenesis of the putative alpha-helical domain of the Vpr protein of human immunodeficiency virus type 1: effect on stability and virion incorporation. Proc Natl Acad Sci U S A (1995) 1.24

Intron-less RNA injected into the nucleus of Xenopus oocytes accesses a regulated translation control pathway. Nucleic Acids Res (1994) 1.24

Restriction of human immunodeficiency virus type 1 production in a human astrocytoma cell line is associated with a cellular block in Rev function. J Virol (1995) 1.23

hRIP, a cellular cofactor for Rev function, promotes release of HIV RNAs from the perinuclear region. Genes Dev (2003) 1.23

Identification of an RNA sequence within an intracisternal-A particle element able to replace Rev-mediated posttranscriptional regulation of human immunodeficiency virus type 1. J Virol (1997) 1.18

Production of avian leukosis virus particles in mammalian cells can be mediated by the interaction of the human immunodeficiency virus protein Rev and the Rev-responsive element. Proc Natl Acad Sci U S A (1995) 1.16

HIV-1 Vpr interacts with a human 34-kDa mov34 homologue, a cellular factor linked to the G2/M phase transition of the mammalian cell cycle. Proc Natl Acad Sci U S A (1998) 1.14

The human T-cell leukemia virus Rex protein. Front Biosci (2005) 1.14

RNA-binding properties of a translational activator, the adenovirus L4 100-kilodalton protein. J Virol (1993) 1.12

Tumultuous relationship between the human immunodeficiency virus type 1 viral infectivity factor (Vif) and the human APOBEC-3G and APOBEC-3F restriction factors. Microbiol Mol Biol Rev (2009) 1.12

The 5' RNA terminus of spleen necrosis virus stimulates translation of nonviral mRNA. J Virol (2000) 1.09

Mutational analysis of the rous sarcoma virus DR posttranscriptional control element. J Virol (1998) 1.06

HIV Rev-dependent binding of SF2/ASF to the Rev response element: possible role in Rev-mediated inhibition of HIV RNA splicing. Proc Natl Acad Sci U S A (1997) 1.06

Nuclear RNA export and packaging functions of HIV-1 Rev revisited. J Virol (2010) 1.05

Potent inhibition of human immunodeficiency virus type 1 (HIV-1) replication by inducible expression of HIV-1 PR multimers. J Virol (1995) 1.04

Visna virus-induced activation of MAPK is required for virus replication and correlates with virus-induced neuropathology. J Virol (2002) 1.04

The signal peptide of a simple retrovirus envelope functions as a posttranscriptional regulator of viral gene expression. J Virol (2009) 1.04

Polypyrimidine tract-binding protein and heterogeneous nuclear ribonucleoprotein A1 bind to human T-cell leukemia virus type 2 RNA regulatory elements. J Virol (1995) 1.03

Activation of bovine leukemia virus transcription in lymphocytes from infected sheep: rapid transition through early to late gene expression. J Virol (1992) 1.03

cis-acting elements in human immunodeficiency virus type 1 RNAs direct viral transcripts to distinct intranuclear locations. J Virol (1996) 1.03

Recruitment of the Crm1 nuclear export factor is sufficient to induce cytoplasmic expression of incompletely spliced human immunodeficiency virus mRNAs. J Virol (2002) 1.03

Phosphorylation regulates RNA binding by the human T-cell leukemia virus Rex protein. J Virol (1992) 1.02

Nuclear export of the human immunodeficiency virus type 1 nucleocytoplasmic shuttle protein Rev is mediated by its activation domain and is blocked by transdominant negative mutants. J Virol (1995) 1.01

Subcellular distribution of human immunodeficiency virus type 1 Rev and colocalization of Rev with RNA splicing factors in a speckled pattern in the nucleoplasm. J Virol (1994) 1.01

Dominant-negative mutants are clustered in a domain of the human T-cell leukemia virus type I Rex protein: implications for trans dominance. J Virol (1992) 1.01

Expression from herpesvirus promoters does not relieve the intron requirement for cytoplasmic accumulation of human beta-globin mRNA. Nucleic Acids Res (1991) 0.98

A specific sequence with a bulged guanosine residue(s) in a stem-bulge-stem structure of Rev-responsive element RNA is required for trans activation by human immunodeficiency virus type 1 Rev. J Virol (1992) 0.98

Human immunodeficiency virus type 1 virions composed of unprocessed Gag and Gag-Pol precursors are capable of reverse transcribing viral genomic RNA. Antimicrob Agents Chemother (1994) 0.96

Jaagsiekte sheep retrovirus encodes a regulatory factor, Rej, required for synthesis of Gag protein. J Virol (2009) 0.96

Rev and Rex proteins of human complex retroviruses function with the MMTV Rem-responsive element. Retrovirology (2009) 0.96

Mapping of the functional boundaries and secondary structure of the mouse mammary tumor virus Rem-responsive element. J Biol Chem (2009) 0.95

Human immunodeficiency virus type 1 Rev is required in vivo for binding of poly(A)-binding protein to Rev-dependent RNAs. J Virol (1994) 0.93

Identification and mutational analysis of a Rej response element in Jaagsiekte sheep retrovirus RNA. J Virol (2009) 0.92

Nuclear interactions are necessary for translational enhancement by spleen necrosis virus RU5. J Virol (2002) 0.92

In vivo binding of wild-type and mutant human immunodeficiency virus type 1 Rev proteins: implications for function. J Virol (1992) 0.90

Within you, without you: HIV-1 Rev and RNA export. Retrovirology (2004) 0.89

Differential trends in the codon usage patterns in HIV-1 genes. PLoS One (2011) 0.88

Inhibition of human immunodeficiency virus type 1 Rev-Rev-response element complex formation by complementary oligonucleotides. J Virol (1992) 0.88

The 5'-untranslated region of the mouse mammary tumor virus mRNA exhibits cap-independent translation initiation. Nucleic Acids Res (2009) 0.88

Identification of a heterogeneous nuclear ribonucleoprotein-recognition region in the HIV Rev protein. J Biol Chem (2009) 0.87

Rev of human immunodeficiency virus and Rex of the human T-cell leukemia virus type I can counteract an mRNA downregulatory element of the transferrin receptor mRNA. Nucleic Acids Res (1994) 0.86

Formation of trans-activation competent HIV-1 Rev:RRE complexes requires the recruitment of multiple protein activation domains. PLoS One (2012) 0.85

From promoting to inhibiting: diverse roles of helicases in HIV-1 Replication. Retrovirology (2012) 0.83

A multifunctional expression vector for an anti-HIV-1 ribozyme that produces a 5'- and 3'-trimmed trans-acting ribozyme, targeted against HIV-1 RNA, and cis-acting ribozymes that are designed to bind to and thereby sequester trans-activator proteins such as Tat and Rev. Nucleic Acids Res (1994) 0.83

Human immunodeficiency virus type 1 Rev-responsive element RNA binds to host cell-specific proteins. J Virol (1994) 0.82

Posttranscriptional regulation of retroviral gene expression: primary RNA transcripts play three roles as pre-mRNA, mRNA, and genomic RNA. Wiley Interdiscip Rev RNA (2013) 0.82

Human chromosome 6- and 11-encoded factors support human immunodeficiency virus type 1 Rev function in A9 cells. J Virol (1996) 0.82

Inhibitory activity of the equine infectious anemia virus major 5' splice site in the absence of Rev. J Virol (1996) 0.82

The RRE of human immunodeficiency virus type 1 contributes to cell-type-specific viral tropism. J Virol (1993) 0.81

Restriction of human immunodeficiency virus type 1 Rev function in murine A9 cells involves the Rev C-terminal domain. J Virol (2003) 0.81

Multi-Faceted Post-Transcriptional Functions of HIV-1 Rev. Biology (Basel) (2012) 0.80

HIV-1 and M-PMV RNA Nuclear Export Elements Program Viral Genomes for Distinct Cytoplasmic Trafficking Behaviors. PLoS Pathog (2016) 0.80

HIV-1 suppressive sequences are modulated by Rev transport of unspliced RNA and are required for efficient HIV-1 production. PLoS One (2012) 0.79

Cooperation between herpes simplex virus type 1-encoded ICP0 and Tat to support transcription of human immunodeficiency virus type 1 long terminal repeat in vivo can occur in the absence of the TAR binding site. J Virol (1996) 0.79

Heterogenous nuclear ribonucleoprotein Q increases protein expression from HIV-1 Rev-dependent transcripts. Virol J (2013) 0.78

CAML does not modulate tetherin-mediated restriction of HIV-1 particle release. PLoS One (2010) 0.78

Importance of codon usage for the temporal regulation of viral gene expression. Proc Natl Acad Sci U S A (2015) 0.77

Depletion of hnRNP A2/B1 overrides the nuclear retention of the HIV-1 genomic RNA. RNA Biol (2013) 0.77

The presence of tat protein or tumor necrosis factor alpha is critical for herpes simplex virus type 1-induced expression of human immunodeficiency virus type 1. J Virol (1994) 0.77

Translational Control of the HIV Unspliced Genomic RNA. Viruses (2015) 0.76

Domain- and nucleotide-specific Rev response element regulation of feline immunodeficiency virus production. Virology (2010) 0.75

Articles by these authors

(truncated to the top 100)

HIV-1 entry into quiescent primary lymphocytes: molecular analysis reveals a labile, latent viral structure. Cell (1990) 17.60

Dual infection of the central nervous system by AIDS viruses with distinct cellular tropisms. Science (1987) 12.77

HIV-1 tropism for mononuclear phagocytes can be determined by regions of gp120 outside the CD4-binding domain. Nature (1990) 9.72

Incompletely reverse-transcribed human immunodeficiency virus type 1 genomes in quiescent cells can function as intermediates in the retroviral life cycle. J Virol (1992) 5.78

The human immunodeficiency virus type 1 vpr gene arrests infected T cells in the G2 + M phase of the cell cycle. J Virol (1995) 4.42

Complete nucleotide sequence of an infectious clone of human T-cell leukemia virus type II: an open reading frame for the protease gene. Proc Natl Acad Sci U S A (1985) 4.28

Clearance of HIV infection in a perinatally infected infant. N Engl J Med (1995) 3.76

The SCID-hu mouse as a model for HIV-1 infection. Nature (1993) 3.43

Identification of the putative transforming protein of the human T-cell leukemia viruses HTLV-I and HTLV-II. Science (1984) 3.39

High levels of unintegrated HIV-1 DNA in brain tissue of AIDS dementia patients. Nature (1990) 3.28

Identification of human immunodeficiency virus envelope gene sequences influencing viral entry into CD4-positive HeLa cells, T-leukemia cells, and macrophages. J Virol (1991) 3.28

Cytokines alter production of HIV-1 from primary mononuclear phagocytes. Science (1988) 3.22

High rate of HTLV-II infection in seropositive i.v. drug abusers in New Orleans. Science (1989) 3.00

Human immunodeficiency virus type 1 Vpr induces apoptosis following cell cycle arrest. J Virol (1997) 2.82

Analysis of rev gene function on human immunodeficiency virus type 1 replication in lymphoid cells by using a quantitative polymerase chain reaction method. J Virol (1989) 2.67

Nucleotide sequence analysis of the long terminal repeat of human T-cell leukemia virus type II. Proc Natl Acad Sci U S A (1984) 2.67

High-efficiency gene transfer into CD34+ cells with a human immunodeficiency virus type 1-based retroviral vector pseudotyped with vesicular stomatitis virus envelope glycoprotein G. J Virol (1996) 2.57

Characterization of reticuloendotheliosis virus strain T DNA and isolation of a novel variant of reticuloendotheliosis virus strain T by molecular cloning. J Virol (1981) 2.49

Identification of the gene responsible for human T-cell leukaemia virus transcriptional regulation. Nature (1986) 2.49

The region of the envelope gene of human immunodeficiency virus type 1 responsible for determination of cell tropism. J Virol (1992) 2.49

Requirement of human immunodeficiency virus type 1 nef for in vivo replication and pathogenicity. J Virol (1994) 2.45

The x gene is essential for HTLV replication. Science (1985) 2.44

Interleukin-1 and tumor necrosis factor alpha can be induced from mononuclear phagocytes by human immunodeficiency virus type 1 binding to the CD4 receptor. J Virol (1989) 2.42

Human T-cell leukemia virus type II transforms normal human lymphocytes. Proc Natl Acad Sci U S A (1983) 2.41

Long terminal repeats of human T-cell leukaemia virus II genome determine target cell specificity. Nature (1984) 2.39

HIV-1 production from infected peripheral blood T cells after HTLV-I induced mitogenic stimulation. Science (1988) 2.37

Molecular characterization of genome of a novel human T-cell leukaemia virus. Nature (1983) 2.36

Kinetics of human immunodeficiency virus type 1 reverse transcription in blood mononuclear phagocytes are slowed by limitations of nucleotide precursors. J Virol (1994) 2.36

Vpr-induced cell cycle arrest is conserved among primate lentiviruses. J Virol (1996) 2.33

Increased susceptibility of differentiated mononuclear phagocytes to productive infection with human immunodeficiency virus-1 (HIV-1). J Clin Invest (1992) 2.28

Establishment of infection by spleen necrosis virus: inhibition in stationary cells and the role of secondary infection. J Virol (1982) 2.26

Genetic analysis of human immunodeficiency virus type 1 integrase and the U3 att site: unusual phenotype of mutants in the zinc finger-like domain. J Virol (1995) 2.22

A mutation in reverse transcriptase of bis(heteroaryl)piperazine-resistant human immunodeficiency virus type 1 that confers increased sensitivity to other nonnucleoside inhibitors. Proc Natl Acad Sci U S A (1993) 2.15

Deoxycytidine kinase from calf thymus. Substrate and inhibitor specificity. J Biol Chem (1976) 2.14

Anti-AIDS agents, 11. Betulinic acid and platanic acid as anti-HIV principles from Syzigium claviflorum, and the anti-HIV activity of structurally related triterpenoids. J Nat Prod (1994) 2.12

Binding of host-cell factors to DNA sequences in the long terminal repeat of human T-cell leukemia virus type I: implications for viral gene expression. Proc Natl Acad Sci U S A (1988) 2.12

Human immunodeficiency virus type 1 T-cell tropism is determined by events prior to provirus formation. J Virol (1990) 2.11

A preponderance of CCR5(+) CXCR4(+) mononuclear cells enhances gastrointestinal mucosal susceptibility to human immunodeficiency virus type 1 infection. J Virol (2001) 2.11

Nucleotide sequence of the 3' region of an infectious human T-cell leukemia virus type II genome. Proc Natl Acad Sci U S A (1984) 2.10

Rapid generation of sequence variation during primary HIV-1 infection. AIDS (1992) 2.08

Functional relation between HTLV-II x and adenovirus E1A proteins in transcriptional activation. Science (1985) 1.87

Cell cycle arrest by Vpr in HIV-1 virions and insensitivity to antiretroviral agents. Science (1998) 1.83

HIV-1 env sequence variation in brain tissue of patients with AIDS-related neurologic disease. J Acquir Immune Defic Syndr (1991) 1.72

Structure of a human DNA repair protein UBA domain that interacts with HIV-1 Vpr. Nat Struct Biol (1998) 1.69

Fate of the human immunodeficiency virus type 1 provirus in infected cells: a role for vpr. J Virol (1995) 1.69

Substitution of 5' helper virus sequences into non-rel portion of reticuloendotheliosis virus strain T suppresses transformation of chicken spleen cells. Cell (1982) 1.69

Mapping genetic determinants for human immunodeficiency virus type 1 resistance to soluble CD4. J Virol (1992) 1.66

HIV-1, macrophages, glial cells, and cytokines in AIDS nervous system disease. FASEB J (1991) 1.66

Studies of the putative transforming protein of the type I human T-cell leukemia virus. Science (1985) 1.65

Envelope proteins from clinical isolates of human immunodeficiency virus type 1 that are refractory to neutralization by soluble CD4 possess high affinity for the CD4 receptor. Proc Natl Acad Sci U S A (1991) 1.62

An inducible human immunodeficiency virus type 1 (HIV-1) vector which effectively suppresses HIV-1 replication. J Virol (1999) 1.61

Human immunodeficiency virus type 1 vpr induces apoptosis through caspase activation. J Virol (2000) 1.61

Regulation of AIDS virus expression. Cell (1986) 1.57

Marking and gene expression by a lentivirus vector in transplanted human and nonhuman primate CD34(+) cells. J Virol (2000) 1.55

Lentiviral delivery of HIV-1 Vpr protein induces apoptosis in transformed cells. Proc Natl Acad Sci U S A (1999) 1.52

Human immunodeficiency virus type 1 vpr gene induces phenotypic effects similar to those of the DNA alkylating agent, nitrogen mustard. J Virol (1997) 1.52

Human immunodeficiency virus type 1 tropism for brain microglial cells is determined by a region of the env glycoprotein that also controls macrophage tropism. J Virol (1992) 1.52

Antibody-directed targeting of retroviral vectors via cell surface antigens. J Virol (2001) 1.50

Characterization and expression of novel singly spliced RNA species of human immunodeficiency virus type 1. J Virol (1990) 1.48

HTLV x-gene product: requirement for the env methionine initiation codon. Science (1985) 1.45

Expression of the 3' terminal region of human T-cell leukemia viruses. Science (1984) 1.44

A second isolate of HTLV-II associated with atypical hairy-cell leukemia. N Engl J Med (1986) 1.44

HTLV-II transactivation is regulated by the overlapping tax/rex nonstructural genes. Science (1988) 1.41

Maternal HIV-1 viral load and vertical transmission of infection: the Ariel Project for the prevention of HIV transmission from mother to infant. Nat Med (1997) 1.41

Structure and expression of c-rel, the cellular homolog to the oncogene of reticuloendotheliosis virus strain T. J Virol (1983) 1.40

Characterization of a novel HTLV-infected cell line. Blood (1984) 1.40

Human immunodeficiency virus type 1 Vpr interacts with HHR23A, a cellular protein implicated in nucleotide excision DNA repair. J Virol (1997) 1.37

Regulation of human T cell leukemia virus expression. FASEB J (1990) 1.36

Detection and cloning of new HTLV-related endogenous sequences in man. Nucleic Acids Res (1989) 1.36

Modeling human lymphoid precursor cell gene therapy in the SCID-hu mouse. Blood (1994) 1.33

Human T-cell leukemia virus type II nucleotide sequences between env and the last exon of tax/rex are not required for viral replication or cellular transformation. J Virol (1995) 1.32

A new reporter system for detection of retroviral infection. Gene Ther (1995) 1.32

Induction of interleukin-1 and tumor necrosis factor alpha in brain cultures by human immunodeficiency virus type 1. J Virol (1992) 1.32

Lentivirus vector-mediated hematopoietic stem cell gene transfer of common gamma-chain cytokine receptor in rhesus macaques. J Virol (2001) 1.30

Anti-human immunodeficiency virus type 1 activity of an oligocationic compound mediated via gp120 V3 interactions. J Virol (1996) 1.27

Human immunodeficiency virus causes mononuclear phagocyte dysfunction. Proc Natl Acad Sci U S A (1990) 1.26

Activation of the GM-CSF promoter by HTLV-I and -II tax proteins. Oncogene (1989) 1.22

Envelope gene of the human endogenous retrovirus HERV-W encodes a functional retrovirus envelope. J Virol (2001) 1.22

Transient renewal of thymopoiesis in HIV-infected human thymic implants following antiviral therapy. Nat Med (1997) 1.21

Potential role of natural killer cells in controlling tumorigenesis by human T-cell leukemia viruses. J Virol (1995) 1.21

A deletion in the proximal untranslated pX region of human T-cell leukemia virus type II decreases viral replication but not infectivity in vivo. Blood (1996) 1.20

A murine leukemia virus (MuLV) long terminal repeat derived from rhesus macaques in the context of a lentivirus vector and MuLV gag sequence results in high-level gene expression in human T lymphocytes. J Virol (2000) 1.19

Biochemical and structural analysis of the interaction between the UBA(2) domain of the DNA repair protein HHR23A and HIV-1 Vpr. Biochemistry (2000) 1.18

Lentiviral-mediated BMP-2 gene transfer enhances healing of segmental femoral defects in rats. Bone (2007) 1.16

Infection with HTLV-I and HTLV-II: evolving concepts. Semin Hematol (1988) 1.14

Ribonucleotides in unintegrated linear spleen necrosis virus DNA. J Virol (1980) 1.12

Human immunodeficiency virus type 1 pathogenesis in SCID-hu mice correlates with syncytium-inducing phenotype and viral replication. J Virol (2000) 1.12

Relative prevalence and risk factors of HTLV-I and HTLV-II infection in US blood donors. Lancet (1991) 1.12

Lentiviral vectors--the promise of gene therapy within reach? Science (1999) 1.07

Modes of transformation by the human T-cell leukemia viruses. Mol Biol Med (1990) 1.06

Establishment of human T-cell leukemia virus type I T-cell lymphomas in severe combined immunodeficient mice. Blood (1993) 1.06

Human T-cell leukemia virus infection of human hematopoietic progenitor cells: maintenance of virus infection during differentiation in vitro and in vivo. J Virol (1996) 1.05

CD26 antigen and HIV fusion? Science (1994) 1.05

A clinical, hematologic, and immunologic analysis of 21 HTLV-II-infected intravenous drug users. Blood (1990) 1.05

The internal methionine codons of human T-cell leukemia virus type II rex gene are not required for p24rex production or virus replication and transformation. J Virol (1990) 1.04

Increased susceptibility of neonatal monocyte/macrophages to HIV-1 infection. AIDS Res Hum Retroviruses (1993) 1.04

Regulation of HTLV-II gene expression by Rex involves positive and negative cis-acting elements in the 5'long terminal repeat. Virology (1991) 1.04

High-efficiency transduction of human lymphoid progenitor cells and expression in differentiated T cells. J Virol (1997) 1.03

In vitro mutagenesis of the human T-cell leukemia virus types I and II tax genes. J Virol (1989) 1.03

Human T-cell leukemia virus type II Rex binding and activity require an intact splice donor site and a specific RNA secondary structure. J Virol (1991) 1.03