Published in Proc Natl Acad Sci U S A on February 21, 2008
The regulation of IL-10 production by immune cells. Nat Rev Immunol (2010) 9.18
c-Maf regulates IL-10 expression during Th17 polarization. J Immunol (2009) 1.99
A risk haplotype of STAT4 for systemic lupus erythematosus is over-expressed, correlates with anti-dsDNA and shows additive effects with two risk alleles of IRF5. Hum Mol Genet (2008) 1.98
The CD46-Jagged1 interaction is critical for human TH1 immunity. Nat Immunol (2012) 1.97
Diversity in the contribution of interleukin-10 to T-cell-mediated immune regulation. Immunol Rev (2008) 1.88
The different faces of Notch in T-helper-cell differentiation. Nat Rev Immunol (2009) 1.61
Cell type-specific regulation of IL-10 expression in inflammation and disease. Immunol Res (2010) 1.32
Regulatory T cells: a role in the control of helminth-driven intestinal pathology and worm survival. J Immunol (2009) 1.29
Notch signal suppresses Toll-like receptor-triggered inflammatory responses in macrophages by inhibiting extracellular signal-regulated kinase 1/2-mediated nuclear factor κB activation. J Biol Chem (2011) 1.21
Role of Blimp-1 in programing Th effector cells into IL-10 producers. J Exp Med (2014) 1.01
IL-10-producing Th1 cells and disease progression are regulated by distinct CD11c⁺ cell populations during visceral leishmaniasis. PLoS Pathog (2012) 1.00
Delta-like ligand 4 regulates central nervous system T cell accumulation during experimental autoimmune encephalomyelitis. J Immunol (2011) 0.99
Stat4 isoforms differentially regulate inflammation and demyelination in experimental allergic encephalomyelitis. J Immunol (2008) 0.98
Role of dendritic cell maturity/costimulation for generation, homeostasis, and suppressive activity of regulatory T cells. Front Immunol (2011) 0.96
Mechanisms underlying the induction of regulatory T cells and its relevance in the adaptive immune response in parasitic infections. Int J Biol Sci (2011) 0.95
T-cell responses induced by allergen-specific immunotherapy. Clin Exp Immunol (2010) 0.94
Timed action of IL-27 protects from immunopathology while preserving defense in influenza. PLoS Pathog (2014) 0.91
Involvement of Notch signaling pathway in regulating IL-12 expression via c-Rel in activated macrophages. Mol Immunol (2012) 0.87
Comparing the immunosuppressive potency of naïve marrow stromal cells and Notch-transfected marrow stromal cells. J Neuroinflammation (2011) 0.85
Stat4 is critical for the balance between Th17 cells and regulatory T cells in colitis. J Immunol (2011) 0.83
Single systemic administration of Ag85B of mycobacteria DNA inhibits allergic airway inflammation in a mouse model of asthma. J Asthma Allergy (2012) 0.80
Mycobacteria-responsive sonic hedgehog signaling mediates programmed death-ligand 1- and prostaglandin E2-induced regulatory T cell expansion. Sci Rep (2016) 0.78
Liver sinusoidal endothelial cells induce tolerance of autoreactive CD4(+) recent thymic emigrants. Sci Rep (2016) 0.78
Complement-Mediated Regulation of Metabolism and Basic Cellular Processes. Immunity (2016) 0.77
Dendritic cells from human mesenteric lymph nodes in inflammatory and non-inflammatory bowel diseases: subsets and function of plasmacytoid dendritic cells. Immunology (2013) 0.77
IL-27 and TGFβ mediated expansion of Th1 and adaptive regulatory T cells expressing IL-10 correlates with bacterial burden and disease severity in pulmonary tuberculosis. Immun Inflamm Dis (2015) 0.77
RBPJ Controls Development of Pathogenic Th17 Cells by Regulating IL-23 Receptor Expression. Cell Rep (2016) 0.76
Complexity and Controversies over the Cytokine Profiles of T Helper Cell Subpopulations in Tuberculosis. J Immunol Res (2015) 0.76
Lck regulates IL-10 expression in memory-like Th1 cells. Eur J Immunol (2010) 0.76
Metallothionein regulates intracellular zinc signaling during CD4(+) T cell activation. BMC Immunol (2016) 0.75
Notch Signaling in T Helper Cell Subsets: Instructor or Unbiased Amplifier? Front Immunol (2017) 0.75
Notch Ligand DLL4 Alleviates Allergic Airway Inflammation via Induction of a Homeostatic Regulatory Pathway. Sci Rep (2017) 0.75
Osteoclast-Primed Foxp3+ CD8 T Cells Induce T-bet, Eomesodermin, and IFN-γ To Regulate Bone Resorption. J Immunol (2016) 0.75
[Self-limitation of inflammatory T-cell responses. Help to self-help as a therapeutic concept]. Z Rheumatol (2008) 0.75
[Therapeutic manipulation of inflammation-promoting T cells: from suppression to self-control]. Z Rheumatol (2013) 0.75
Interleukin-10 and the interleukin-10 receptor. Annu Rev Immunol (2001) 25.63
Functional diversity of helper T lymphocytes. Nature (1996) 18.09
A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis. Nature (1997) 16.28
An essential role for interleukin 10 in the function of regulatory T cells that inhibit intestinal inflammation. J Exp Med (1999) 10.67
Selected Toll-like receptor agonist combinations synergistically trigger a T helper type 1-polarizing program in dendritic cells. Nat Immunol (2005) 6.81
Induction of interleukin 10-producing, nonproliferating CD4(+) T cells with regulatory properties by repetitive stimulation with allogeneic immature human dendritic cells. J Exp Med (2000) 6.45
A dominant function for interleukin 27 in generating interleukin 10-producing anti-inflammatory T cells. Nat Immunol (2007) 6.20
Interleukins 27 and 6 induce STAT3-mediated T cell production of interleukin 10. Nat Immunol (2007) 5.99
Instruction of distinct CD4 T helper cell fates by different notch ligands on antigen-presenting cells. Cell (2004) 5.50
In vitro generation of interleukin 10-producing regulatory CD4(+) T cells is induced by immunosuppressive drugs and inhibited by T helper type 1 (Th1)- and Th2-inducing cytokines. J Exp Med (2002) 5.28
Suppression of autoimmune inflammation of the central nervous system by interleukin 10 secreted by interleukin 27-stimulated T cells. Nat Immunol (2007) 4.66
CD4(+)CD25(-)Foxp3(-) Th1 cells are the source of IL-10-mediated immune suppression in chronic cutaneous leishmaniasis. J Exp Med (2007) 4.66
Conventional T-bet(+)Foxp3(-) Th1 cells are the major source of host-protective regulatory IL-10 during intracellular protozoan infection. J Exp Med (2007) 4.47
Conditional deletion of Gata3 shows its essential function in T(H)1-T(H)2 responses. Nat Immunol (2004) 4.41
Direct regulation of Gata3 expression determines the T helper differentiation potential of Notch. Immunity (2007) 3.19
Interleukin-2 is essential for CD4+CD25+ regulatory T cell function. Eur J Immunol (2004) 3.08
Regulation of alphabeta/gammadelta T cell lineage commitment and peripheral T cell responses by Notch/RBP-J signaling. Immunity (2004) 3.01
Notch directly regulates Gata3 expression during T helper 2 cell differentiation. Immunity (2007) 2.88
Notch signaling is an important regulator of type 2 immunity. J Exp Med (2005) 2.87
Inhibitors of gamma-secretase block in vivo and in vitro T helper type 1 polarization by preventing Notch upregulation of Tbx21. Nat Immunol (2005) 2.81
Flow cytometric determination of cytokines in activated murine T helper lymphocytes: expression of interleukin-10 in interferon-gamma and in interleukin-4-expressing cells. Eur J Immunol (1994) 2.65
Interleukin-12 primes human CD4 and CD8 T cell clones for high production of both interferon-gamma and interleukin-10. J Exp Med (1996) 2.36
Delta1-Notch3 interactions bias the functional differentiation of activated CD4+ T cells. Immunity (2003) 2.34
In the absence of IL-12, CD4(+) T cell responses to intracellular pathogens fail to default to a Th2 pattern and are host protective in an IL-10(-/-) setting. Immunity (2002) 2.23
Notch signalling during peripheral T-cell activation and differentiation. Nat Rev Immunol (2006) 2.18
CD4(+) T cell clones producing both interferon-gamma and interleukin-10 predominate in bronchoalveolar lavages of active pulmonary tuberculosis patients. Clin Immunol (1999) 2.01
Notch signaling augments T cell responsiveness by enhancing CD25 expression. J Immunol (2003) 1.95
CD8- DCs induce IL-12-independent Th1 differentiation through Delta 4 Notch-like ligand in response to bacterial LPS. J Exp Med (2007) 1.86
Notch 1 signaling regulates peripheral T cell activation. Immunity (2004) 1.61
IL-12-induced IL-10 production by human T cells as a negative feedback for IL-12-induced immune responses. J Immunol (1996) 1.54
Tyk2 negatively regulates adaptive Th1 immunity by mediating IL-10 signaling and promoting IFN-gamma-dependent IL-10 reactivation. J Immunol (2006) 1.53
The interleukin-4 enhancer CNS-2 is regulated by Notch signals and controls initial expression in NKT cells and memory-type CD4 T cells. Immunity (2006) 1.53
Expression of IL-10 in Th memory lymphocytes is conditional on IL-12 or IL-4, unless the IL-10 gene is imprinted by GATA-3. Eur J Immunol (2007) 1.34
Overexpression of the Notch ligand, Jagged-1, induces alloantigen-specific human regulatory T cells. Blood (2003) 1.23
Notch ligands Delta-like1, Delta-like4 and Jagged1 differentially regulate activation of peripheral T helper cells. Eur J Immunol (2005) 1.18
Serrate1-induced notch signalling regulates the decision between immunity and tolerance made by peripheral CD4(+) T cells. Int Immunol (2000) 1.17
Developmental stage, phenotype, and migration distinguish naive- and effector/memory-like CD4+ regulatory T cells. J Exp Med (2004) 5.08
Expression of the integrin alpha Ebeta 7 identifies unique subsets of CD25+ as well as CD25- regulatory T cells. Proc Natl Acad Sci U S A (2002) 3.41
Interleukin-2 is essential for CD4+CD25+ regulatory T cell function. Eur J Immunol (2004) 3.08
Direct access to CD4+ T cells specific for defined antigens according to CD154 expression. Nat Med (2005) 2.92
CD14+CD34low cells with stem cell phenotypic and functional features are the major source of circulating endothelial progenitors. Circ Res (2005) 2.62
Migration matters: regulatory T-cell compartmentalization determines suppressive activity in vivo. Blood (2005) 2.55
MIP-1alpha, MIP-1beta, RANTES, and ATAC/lymphotactin function together with IFN-gamma as type 1 cytokines. Proc Natl Acad Sci U S A (2002) 1.79
Competing feedback loops shape IL-2 signaling between helper and regulatory T lymphocytes in cellular microenvironments. Proc Natl Acad Sci U S A (2010) 1.71
Origin and functional activity of the membrane-bound glucocorticoid receptor. Arthritis Rheum (2011) 1.59
Design of siRNAs producing unstructured guide-RNAs results in improved RNA interference efficiency. Nat Biotechnol (2005) 1.47
Autoregulation of Th1-mediated inflammation by twist1. J Exp Med (2008) 1.43
Homeostatic imbalance of regulatory and effector T cells due to IL-2 deprivation amplifies murine lupus. Proc Natl Acad Sci U S A (2009) 1.38
IL-2 induces in vivo suppression by CD4(+)CD25(+)Foxp3(+) regulatory T cells. Eur J Immunol (2008) 1.34
The role of regulatory T cells in antigen-induced arthritis: aggravation of arthritis after depletion and amelioration after transfer of CD4+CD25+ T cells. Arthritis Res Ther (2005) 1.34
Rapid glucocorticoid effects on immune cells. Steroids (2002) 1.32
Competition for cytokines: T(reg) cells take all. Nat Immunol (2007) 1.30
siRNA stabilization prolongs gene knockdown in primary T lymphocytes. Eur J Immunol (2008) 1.30
Functional analysis of effector and regulatory T cells in a parasitic nematode infection. Infect Immun (2008) 1.25
Cutting edge: Plasmacytoid dendritic cells induce IL-10 production in T cells via the Delta-like-4/Notch axis. J Immunol (2009) 1.22
Visualization of peptide presentation following oral application of antigen in normal and Peyer's patches-deficient mice. Eur J Immunol (2003) 1.19
Notch ligands Delta-like1, Delta-like4 and Jagged1 differentially regulate activation of peripheral T helper cells. Eur J Immunol (2005) 1.18
Identification and isolation of murine antigen-reactive T cells according to CD154 expression. Eur J Immunol (2007) 1.15
Lipopolysaccharide injection induces relapses of experimental autoimmune encephalomyelitis in nontransgenic mice via bystander activation of autoreactive CD4+ cells. J Immunol (2005) 1.06
Human CD4(+) T cells maintain specific functions even under conditions of extremely restricted ATP production. Eur J Immunol (2008) 1.03
Differential surrogate light chain expression governs B-cell differentiation. Blood (2002) 1.03
Human immature myeloid dendritic cells trigger a TH2-polarizing program via Jagged-1/Notch interaction. J Allergy Clin Immunol (2008) 1.02
High IFN-gamma production of individual CD8 T lymphocytes is controlled by CD152 (CTLA-4). J Immunol (2007) 1.02
Monitoring regulatory T cells in clinical samples: consensus on an essential marker set and gating strategy for regulatory T cell analysis by flow cytometry. Cancer Immunol Immunother (2015) 0.99
miR-148a is upregulated by Twist1 and T-bet and promotes Th1-cell survival by regulating the proapoptotic gene Bim. Eur J Immunol (2015) 0.98
Flow-cytometric analysis of rare antigen-specific T cells. Cytometry A (2013) 0.96
Persistence of effector memory Th1 cells is regulated by Hopx. Eur J Immunol (2010) 0.91
Antigen-reactive T cell enrichment for direct, high-resolution analysis of the human naive and memory Th cell repertoire. J Immunol (2013) 0.90
Fine tuning and efficient T cell activation with stimulatory aCD3 nanoarrays. Nano Lett (2013) 0.85
Clinical-scale selection and viral transduction of human naïve and central memory CD8+ T cells for adoptive cell therapy of cancer patients. Cancer Immunol Immunother (2013) 0.84
Antigen-specific cytometry--new tools arrived! Clin Immunol (2004) 0.83
In-vitro-induced Th17 cells fail to induce inflammation in vivo and show an impaired migration into inflamed sites. Eur J Immunol (2010) 0.83
Single-cell analysis of the murine chemokines MIP-1alpha, MIP-1beta, RANTES and ATAC/lymphotactin by flow cytometry. J Immunol Methods (2003) 0.80
Establishment of early lymphoid organ infrastructure in transplanted tumors mediated by local production of lymphotoxin alpha and in the combined absence of functional B and T cells. J Immunol (2004) 0.79
Fungus-specific CD4(+) T cells for rapid identification of invasive pulmonary mold infection. Am J Respir Crit Care Med (2015) 0.78
Towards in vivo application of RNA interference - new toys, old problems. Arthritis Res Ther (2004) 0.77
Sensitive visualization of peptide presentation in vitro and ex vivo. Cytometry A (2003) 0.76
High-sensitivity immunofluorescence staining: a comparison of the liposome procedure and the FASER technique on mGR detection. J Fluoresc (2013) 0.75
Membrane glucocorticoid receptor expression on peripheral blood mononuclear cells in patients with ankylosing spondylitis. J Rheumatol (2006) 0.75