Published in Am J Hum Genet on February 21, 2008
A generalized family-based association test for dichotomous traits. Am J Hum Genet (2009) 1.70
Mapping quantitative traits in unselected families: algorithms and examples. Genet Epidemiol (2009) 1.00
Genome-wide linkage scan to identify loci associated with type 2 diabetes and blood lipid phenotypes in the Sikh Diabetes Study. PLoS One (2011) 0.86
Applying novel genome-wide linkage strategies to search for loci influencing type 2 diabetes and adult height in American Samoa. Hum Biol (2008) 0.76
Variance components linkage analysis with repeated measurements. Hum Hered (2008) 0.75
Heritability Estimation using Regression Models for Correlation. J Biom Biostat (2011) 0.75
Multipoint quantitative-trait linkage analysis in general pedigrees. Am J Hum Genet (1998) 40.97
The investigation of linkage between a quantitative trait and a marker locus. Behav Genet (1972) 24.92
Robust variance-components approach for assessing genetic linkage in pedigrees. Am J Hum Genet (1994) 10.58
Powerful regression-based quantitative-trait linkage analysis of general pedigrees. Am J Hum Genet (2002) 5.20
Testing the robustness of the likelihood-ratio test in a variance-component quantitative-trait loci-mapping procedure. Am J Hum Genet (1999) 4.54
Mapping quantitative trait loci in oligogenic models. Biostatistics (2001) 2.41
Equivalence between Haseman-Elston and variance-components linkage analyses for sib pairs. Am J Hum Genet (2001) 2.16
A score-statistic approach for the mapping of quantitative-trait loci with sibships of arbitrary size. Am J Hum Genet (2001) 1.67
Score test for detecting linkage to quantitative traits. Genet Epidemiol (2002) 1.53
Variance-Components QTL linkage analysis of selected and non-normal samples: conditioning on trait values. Genet Epidemiol (2000) 1.48
A powerful and robust method for mapping quantitative trait loci in general pedigrees. Am J Hum Genet (2005) 1.29
Quantitative trait linkage analysis by generalized estimating equations: unification of variance components and Haseman-Elston regression. Genet Epidemiol (2004) 1.16
Recent advances in human quantitative-trait-locus mapping: comparison of methods for discordant sibling pairs. Am J Hum Genet (2003) 1.14
Recent advances in human quantitative-trait-locus mapping: comparison of methods for selected sibling pairs. Am J Hum Genet (2003) 1.09
Power and robustness of linkage tests for quantitative traits in general pedigrees. Genet Epidemiol (2005) 0.99
Score test for detecting linkage to complex traits in selected samples. Genet Epidemiol (2004) 0.93
Score test for mapping quantitative-trait loci with sibships of arbitrary size when the dominance effect is not negligible. Genet Epidemiol (2002) 0.91
QTL mapping under ascertainment. Ann Hum Genet (2006) 0.88
A likelihood approach for quantitative-trait-locus mapping with selected pedigrees. Biometrics (2005) 0.81
The elusive goal of pedigree weights. Genet Epidemiol (2007) 0.80
Mapping autism risk loci using genetic linkage and chromosomal rearrangements. Nat Genet (2007) 14.05
Genome partitioning of genetic variation for complex traits using common SNPs. Nat Genet (2011) 8.57
Susceptibility genes for age-related maculopathy on chromosome 10q26. Am J Hum Genet (2005) 4.91
Genetic variants near TIMP3 and high-density lipoprotein-associated loci influence susceptibility to age-related macular degeneration. Proc Natl Acad Sci U S A (2010) 4.30
Interpretation of genetic association studies: markers with replicated highly significant odds ratios may be poor classifiers. PLoS Genet (2009) 4.22
Seven new loci associated with age-related macular degeneration. Nat Genet (2013) 3.81
Detectable clonal mosaicism from birth to old age and its relationship to cancer. Nat Genet (2012) 3.68
The Gene, Environment Association Studies consortium (GENEVA): maximizing the knowledge obtained from GWAS by collaboration across studies of multiple conditions. Genet Epidemiol (2010) 3.48
Comprehensive literature review and statistical considerations for microarray meta-analysis. Nucleic Acids Res (2012) 2.54
Mega2: data-handling for facilitating genetic linkage and association analyses. Bioinformatics (2005) 2.53
Association tests using kernel-based measures of multi-locus genotype similarity between individuals. Genet Epidemiol (2010) 2.39
Meta-analysis of genome scans of age-related macular degeneration. Hum Mol Genet (2005) 2.34
Genetic analysis of variation in human meiotic recombination. PLoS Genet (2009) 2.11
Candidate gene analysis suggests a role for fatty acid biosynthesis and regulation of the complement system in the etiology of age-related maculopathy. Hum Mol Genet (2005) 2.04
Decreased expression of miR-125b and miR-100 in oral cancer cells contributes to malignancy. Genes Chromosomes Cancer (2009) 1.98
What's the best statistic for a simple test of genetic association in a case-control study? Genet Epidemiol (2010) 1.95
Laparoscopic liver resection: an examination of our first 300 patients. J Am Coll Surg (2011) 1.91
Regression-based quantitative-trait-locus mapping in the 21st century. Am J Hum Genet (2002) 1.87
Peripheral blood mononuclear cell gene expression profiles predict poor outcome in idiopathic pulmonary fibrosis. Sci Transl Med (2013) 1.81
Genomewide linkage study in 1,176 affected sister pair families identifies a significant susceptibility locus for endometriosis on chromosome 10q26. Am J Hum Genet (2005) 1.76
Comprehensive literature review and statistical considerations for GWAS meta-analysis. Nucleic Acids Res (2012) 1.75
New insights into human nondisjunction of chromosome 21 in oocytes. PLoS Genet (2008) 1.68
CFH, ELOVL4, PLEKHA1 and LOC387715 genes and susceptibility to age-related maculopathy: AREDS and CHS cohorts and meta-analyses. Hum Mol Genet (2006) 1.58
Candidate-gene screening and association analysis at the autism-susceptibility locus on chromosome 16p: evidence of association at GRIN2A and ABAT. Am J Hum Genet (2005) 1.56
Replication of a genome-wide association study of birth weight in preterm neonates. J Pediatr (2011) 1.45
An evaluation of 2537 gastrointestinal stromal tumors for a proposed clinical staging system. Arch Surg (2009) 1.42
Improving outcomes in elderly patients with community-acquired pneumonia by adhering to national guidelines: Community-Acquired Pneumonia Organization International cohort study results. Arch Intern Med (2009) 1.40
Identification of a rare coding variant in complement 3 associated with age-related macular degeneration. Nat Genet (2013) 1.39
Ordered subset linkage analysis supports a susceptibility locus for age-related macular degeneration on chromosome 16p12. BMC Genet (2004) 1.27
Association between maternal age and meiotic recombination for trisomy 21. Am J Hum Genet (2004) 1.23
C2 and CFB genes in age-related maculopathy and joint action with CFH and LOC387715 genes. PLoS One (2008) 1.22
Variations in apolipoprotein E frequency with age in a pooled analysis of a large group of older people. Am J Epidemiol (2011) 1.19
Familial aggregation of endometriosis in a large pedigree of rhesus macaques. Hum Reprod (2004) 1.18
GJC2 missense mutations cause human lymphedema. Am J Hum Genet (2010) 1.17
Evidence of association of APOE with age-related macular degeneration: a pooled analysis of 15 studies. Hum Mutat (2011) 1.17
ADCYAP1R1 and asthma in Puerto Rican children. Am J Respir Crit Care Med (2013) 1.17
Epidemiological trends of suicide and attempted suicide by poisoning in the US: 2000-2008. Leg Med (Tokyo) (2010) 1.15
Skeletal muscle fatigue, strength, and quality in the elderly: the Health ABC Study. J Appl Physiol (1985) (2005) 1.15
Biological impact of missing-value imputation on downstream analyses of gene expression profiles. Bioinformatics (2010) 1.15
Recent advances in human quantitative-trait-locus mapping: comparison of methods for discordant sibling pairs. Am J Hum Genet (2003) 1.14
Variation in folate pathway genes contributes to risk of congenital heart defects among individuals with Down syndrome. Genet Epidemiol (2010) 1.14
Complement factor H genetic variant and age-related macular degeneration: effect size, modifiers and relationship to disease subtype. Int J Epidemiol (2012) 1.12
Etiology of Down syndrome: Evidence for consistent association among altered meiotic recombination, nondisjunction, and maternal age across populations. Am J Med Genet A (2009) 1.11
A genome-wide linkage scan identifies multiple chromosomal regions influencing serum lipid levels in the population on the Samoan islands. J Lipid Res (2008) 1.11
Recent advances in human quantitative-trait-locus mapping: comparison of methods for selected sibling pairs. Am J Hum Genet (2003) 1.09
Footer: a quantitative comparative genomics method for efficient recognition of cis-regulatory elements. Genome Res (2005) 1.09
The Khatri Sikh Diabetes Study (SDS): study design, methodology, sample collection, and initial results. Hum Biol (2006) 1.08
Heritable patterns of tooth decay in the permanent dentition: principal components and factor analyses. BMC Oral Health (2012) 1.07
Genetic variation in fatty acid-binding protein-4 and peroxisome proliferator-activated receptor gamma interactively influence insulin sensitivity and body composition in males. Metabolism (2004) 1.07
Prevalence of adiposity and associated cardiometabolic risk factors in the Samoan genome-wide association study. Am J Hum Biol (2014) 1.06
Genome-wide association scan of dental caries in the permanent dentition. BMC Oral Health (2012) 1.06
A genome-wide scan for loci affecting normal adult height in the Framingham Heart Study. Hum Hered (2003) 1.04
SNPs made routine. Nat Methods (2004) 1.04
Linkage disequilibrium mapping in trisomic populations: analytical approaches and an application to congenital heart defects in Down syndrome. Genet Epidemiol (2004) 1.03
Referral to cancer genetic counseling: are there stages of readiness? Am J Med Genet C Semin Med Genet (2006) 1.02
Interaction among variant vascular endothelial growth factor (VEGF) and its receptor in relation to prostate cancer risk. Prostate (2010) 1.02
An excess of deleterious variants in VEGF-A pathway genes in Down-syndrome-associated atrioventricular septal defects. Am J Hum Genet (2012) 1.01
Genetics. Genetic control of hotspots. Science (2010) 1.01
FOOTER: a web tool for finding mammalian DNA regulatory regions using phylogenetic footprinting. Nucleic Acids Res (2005) 0.99
Altered patterns of multiple recombinant events are associated with nondisjunction of chromosome 21. Hum Genet (2011) 0.99
Otitis media: a genome-wide linkage scan with evidence of susceptibility loci within the 17q12 and 10q22.3 regions. BMC Med Genet (2009) 0.99
Mass spectral determination of fasting tear glucose concentrations in nondiabetic volunteers. Clin Chem (2007) 0.98
A genome-wide association study of chronic otitis media with effusion and recurrent otitis media identifies a novel susceptibility locus on chromosome 2. J Assoc Res Otolaryngol (2013) 0.97
Comparative study of multipoint methods for genotype error detection. Hum Hered (2004) 0.97
Susceptibility loci for adiposity phenotypes on 8p, 9p, and 16q in American Samoa and Samoa. Obesity (Silver Spring) (2008) 0.97
Mortality differences among hospitalized patients with community-acquired pneumonia in three world regions: results from the Community-Acquired Pneumonia Organization (CAPO) International Cohort Study. Respir Med (2013) 0.96
Distribution of genome-wide linkage disequilibrium based on microsatellite loci in the Samoan population. Hum Genomics (2004) 0.96
Increased expression of interferon-inducible genes in macaque lung tissues during simian immunodeficiency virus infection. Microbes Infect (2006) 0.95
Linkage analysis of adult height with parent-of-origin effects in the Framingham Heart Study. BMC Genet (2003) 0.95
Interrogating differences in expression of targeted gene sets to predict breast cancer outcome. BMC Cancer (2013) 0.95
Gender-specific association of ATP-binding cassette transporter 1 (ABCA1) polymorphisms with the risk of late-onset Alzheimer's disease. Neurobiol Aging (2006) 0.94
Interaction among apoptosis-associated sequence variants and joint effects on aggressive prostate cancer. BMC Med Genomics (2012) 0.94
Pooling-based genome-wide association study implicates gamma-glutamyltransferase 1 (GGT1) gene in pancreatic carcinogenesis. Pancreatology (2010) 0.94
Significant evidence of one or more susceptibility loci for endometriosis with near-Mendelian inheritance on chromosome 7p13-15. Hum Reprod (2006) 0.93
Examination of polymorphic glutathione S-transferase (GST) genes, tobacco smoking and prostate cancer risk among men of African descent: a case-control study. BMC Cancer (2009) 0.93
Smarter clustering methods for SNP genotype calling. Bioinformatics (2008) 0.93
Genetic variants in major histocompatibility complex-linked genes associate with pediatric liver transplant rejection. Gastroenterology (2008) 0.93
The origin of trisomy 22: evidence for acrocentric chromosome-specific patterns of nondisjunction. Am J Med Genet A (2007) 0.91
Genome-wide microarray expression analysis of CD4+ T Cells from nonobese diabetic congenic mice identifies Cd55 (Daf1) and Acadl as candidate genes for type 1 diabetes. J Immunol (2008) 0.91
Regulatory conservation of protein coding and microRNA genes in vertebrates: lessons from the opossum genome. Genome Biol (2007) 0.90
Genome-wide association study of periodontal health measured by probing depth in adults ages 18-49 years. G3 (Bethesda) (2014) 0.90
Connexin 47 mutations increase risk for secondary lymphedema following breast cancer treatment. Clin Cancer Res (2012) 0.89
Predictive accuracy of the pneumonia severity index vs CRB-65 for time to clinical stability: results from the Community-Acquired Pneumonia Organization (CAPO) International Cohort Study. Respir Med (2010) 0.89
S-adenosylmethionine decreases lipopolysaccharide-induced phosphodiesterase 4B2 and attenuates tumor necrosis factor expression via cAMP/protein kinase A pathway. J Pharmacol Exp Ther (2011) 0.89
Investigation of factors associated with paternal nondisjunction of chromosome 21. Am J Med Genet A (2009) 0.89
Epidemiology of Down syndrome: new insight into the multidimensional interactions among genetic and environmental risk factors in the oocyte. Am J Epidemiol (2011) 0.89
Dopaminergic mutations: within-family association and linkage in multiplex alcohol dependence families. Am J Med Genet B Neuropsychiatr Genet (2008) 0.88
A comparison of principal component analysis and factor analysis strategies for uncovering pleiotropic factors. Genet Epidemiol (2009) 0.88
Evidence for a SULT4A1 haplotype correlating with baseline psychopathology and atypical antipsychotic response. Pharmacogenomics (2011) 0.88
NOD2 gene polymorphism rs2066844 associates with need for combined liver-intestine transplantation in children with short-gut syndrome. Am J Gastroenterol (2010) 0.88
A powerful and robust new linkage statistic for discordant sibling pairs. Am J Hum Genet (2004) 0.87
QTL mapping with discordant and concordant sibling pairs: new statistics and new design strategies. Genet Epidemiol (2005) 0.87