Published in Genet Epidemiol on May 01, 2010
Genome partitioning of genetic variation for complex traits using common SNPs. Nat Genet (2011) 8.57
Cleft lip and palate: understanding genetic and environmental influences. Nat Rev Genet (2011) 5.41
Quality control and quality assurance in genotypic data for genome-wide association studies. Genet Epidemiol (2010) 4.83
Detectable clonal mosaicism from birth to old age and its relationship to cancer. Nat Genet (2012) 3.68
A high-performance computing toolset for relatedness and principal component analysis of SNP data. Bioinformatics (2012) 3.36
Variation in actual relationship as a consequence of Mendelian sampling and linkage. Genet Res (Camb) (2011) 2.56
Quality, quantity and harmony: the DataSHaPER approach to integrating data across bioclinical studies. Int J Epidemiol (2010) 2.44
Genome-wide association study identifies novel loci predisposing to cutaneous melanoma. Hum Mol Genet (2011) 2.26
Prediction of complex human traits using the genomic best linear unbiased predictor. PLoS Genet (2013) 2.16
Genome-wide association scan for childhood caries implicates novel genes. J Dent Res (2011) 2.05
Common variants at 9p21 and 8q22 are associated with increased susceptibility to optic nerve degeneration in glaucoma. PLoS Genet (2012) 2.00
Common variants near CAV1 and CAV2 are associated with primary open-angle glaucoma in Caucasians from the USA. Hum Mol Genet (2011) 1.77
Mayo Genome Consortia: a genotype-phenotype resource for genome-wide association studies with an application to the analysis of circulating bilirubin levels. Mayo Clin Proc (2011) 1.62
Assessing and managing risk when sharing aggregate genetic variant data. Nat Rev Genet (2011) 1.62
The evolution of human genetic studies of cleft lip and cleft palate. Annu Rev Genomics Hum Genet (2012) 1.58
Copy number variations in 6q14.1 and 5q13.2 are associated with alcohol dependence. Alcohol Clin Exp Res (2012) 1.50
GWASTools: an R/Bioconductor package for quality control and analysis of genome-wide association studies. Bioinformatics (2012) 1.48
Challenges and opportunities in genome-wide environmental interaction (GWEI) studies. Hum Genet (2012) 1.37
Gene-environment interplay in common complex diseases: forging an integrative model—recommendations from an NIH workshop. Genet Epidemiol (2011) 1.33
Genomic heritability: what is it? PLoS Genet (2015) 1.31
Phenotype harmonization and cross-study collaboration in GWAS consortia: the GENEVA experience. Genet Epidemiol (2011) 1.29
Genetics of nonsyndromic orofacial clefts. Cleft Palate Craniofac J (2011) 1.27
A genome-wide association study of venous thromboembolism identifies risk variants in chromosomes 1q24.2 and 9q. J Thromb Haemost (2012) 1.23
Genome-wide association study of conduct disorder symptomatology. Mol Psychiatry (2010) 1.22
Genome-wide association study of lung function decline in adults with and without asthma. J Allergy Clin Immunol (2012) 1.20
Genome-wide association study of primary tooth eruption identifies pleiotropic loci associated with height and craniofacial distances. Hum Mol Genet (2013) 1.17
Genome-wide association study of dermatomyositis reveals genetic overlap with other autoimmune disorders. Arthritis Rheum (2013) 1.12
A genome-wide association study of DSM-IV cannabis dependence. Addict Biol (2010) 1.12
Genetic susceptibility to dental caries on pit and fissure and smooth surfaces. Caries Res (2012) 1.08
Heritable patterns of tooth decay in the permanent dentition: principal components and factor analyses. BMC Oral Health (2012) 1.07
The NEIGHBOR consortium primary open-angle glaucoma genome-wide association study: rationale, study design, and clinical variables. J Glaucoma (2013) 1.06
Genome-wide association scan of dental caries in the permanent dentition. BMC Oral Health (2012) 1.06
Genome-wide analysis of central corneal thickness in primary open-angle glaucoma cases in the NEIGHBOR and GLAUGEN consortia. Invest Ophthalmol Vis Sci (2012) 1.06
Harmonizing the classification of age-related macular degeneration in the three-continent AMD consortium. Ophthalmic Epidemiol (2014) 1.01
A novel method for identifying nonlinear gene-environment interactions in case-control association studies. Hum Genet (2013) 1.00
Data compatibility in the addiction sciences: an examination of measure commonality. Drug Alcohol Depend (2014) 1.00
Measuring alcohol consumption for genomic meta-analyses of alcohol intake: opportunities and challenges. Am J Clin Nutr (2012) 0.99
Genome-wide association study and meta-analysis of intraocular pressure. Hum Genet (2013) 0.98
Using PhenX measures to identify opportunities for cross-study analysis. Hum Mutat (2012) 0.96
The primary open-angle african american glaucoma genetics study: baseline demographics. Ophthalmology (2015) 0.96
GALC deletions increase the risk of primary open-angle glaucoma: the role of Mendelian variants in complex disease. PLoS One (2011) 0.94
Rare variants in ischemic stroke: an exome pilot study. PLoS One (2012) 0.92
Environmental influences on systemic lupus erythematosus expression. Rheum Dis Clin North Am (2014) 0.92
Estrogen pathway polymorphisms in relation to primary open angle glaucoma: an analysis accounting for gender from the United States. Mol Vis (2013) 0.90
Copy number variation accuracy in genome-wide association studies. Hum Hered (2011) 0.90
Contemporary human genetic strategies in aging research. Ageing Res Rev (2010) 0.89
A genome-wide study of de novo deletions identifies a candidate locus for non-syndromic isolated cleft lip/palate risk. BMC Genet (2014) 0.88
GWAS reveals new recessive loci associated with non-syndromic facial clefting. Eur J Med Genet (2012) 0.88
Contrasting genetic architectures in different mouse reference populations used for studying complex traits. Genome Res (2015) 0.86
Fast detection of de novo copy number variants from SNP arrays for case-parent trios. BMC Bioinformatics (2012) 0.86
Chromosomal variation in lymphoblastoid cell lines. Hum Mutat (2012) 0.86
Genetic factors influencing risk to orofacial clefts: today's challenges and tomorrow's opportunities. F1000Res (2016) 0.85
Genetic susceptibility to dental caries differs between the sexes: a family-based study. Caries Res (2015) 0.84
Genome-wide association study identified the human leukocyte antigen region as a novel locus for plasma beta-2 microglobulin. Hum Genet (2013) 0.84
Incidental genetic findings in randomized clinical trials: recommendations from the Genomics and Randomized Trials Network (GARNET). Genome Med (2013) 0.84
Genome-wide association studies and large-scale collaborations in epidemiology. Eur J Epidemiol (2010) 0.84
Genome-wide association study identifies four loci associated with eruption of permanent teeth. PLoS Genet (2011) 0.84
Replication of genome wide association studies of alcohol dependence: support for association with variation in ADH1C. PLoS One (2013) 0.84
CDKN2B-AS1 genotype-glaucoma feature correlations in primary open-angle glaucoma patients from the United States. Am J Ophthalmol (2012) 0.83
Variation in actual relationship among descendants of inbred individuals. Genet Res (Camb) (2012) 0.82
Calibrating longitudinal cognition in Alzheimer's disease across diverse test batteries and datasets. Neuroepidemiology (2014) 0.82
The case for launch of an international DNA-based birth cohort study. J Glob Health (2011) 0.82
Challenges in Studying Modifiable Risk Factors for Birth Defects. Curr Epidemiol Rep (2015) 0.80
DNA copy number variants of known glaucoma genes in relation to primary open-angle glaucoma. Invest Ophthalmol Vis Sci (2014) 0.80
The influence of genetic susceptibility and calcium plus vitamin D supplementation on fracture risk. Am J Clin Nutr (2017) 0.80
Database of genetic studies of bipolar disorder. Psychiatr Genet (2011) 0.80
A General and Robust Framework for Secondary Traits Analysis. Genetics (2016) 0.79
Public health in the genomic era: will Public Health Genomics contribute to major changes in the prevention of common diseases? Arch Public Health (2011) 0.78
Variation in HNF1B and Obesity May Influence Prostate Cancer Risk in African American Men: A Pilot Study. Prostate Cancer (2013) 0.78
Genes, environments, and developmental research: methods for a multi-site study of early substance abuse. Twin Res Hum Genet (2013) 0.78
Integrative analysis of gene-environment interactions under a multi-response partially linear varying coefficient model. Stat Med (2014) 0.78
A set-based association test identifies sex-specific gene sets associated with type 2 diabetes. Front Genet (2014) 0.77
A genome-wide study of inherited deletions identified two regions associated with nonsyndromic isolated oral clefts. Birth Defects Res A Clin Mol Teratol (2015) 0.76
Detecting gene-environment interactions in human birth defects: Study designs and statistical methods. Birth Defects Res A Clin Mol Teratol (2015) 0.75
Assessing the Association of Mitochondrial Genetic Variation With Primary Open-Angle Glaucoma Using Gene-Set Analyses. Invest Ophthalmol Vis Sci (2016) 0.75
A Scale-Corrected Comparison of Linkage Disequilibrium Levels between Genic and Non-Genic Regions. PLoS One (2015) 0.75
Genome-wide analyses of non-syndromic cleft lip with palate identify 14 novel loci and genetic heterogeneity. Nat Commun (2017) 0.75
A global test for gene-gene interactions based on random matrix theory. Genet Epidemiol (2016) 0.75
Network-based regularization for high dimensional SNP data in the case-control study of Type 2 diabetes. BMC Genet (2017) 0.75
Risk prediction models for oral clefts allowing for phenotypic heterogeneity. Front Genet (2015) 0.75
CLEFT LIP, ALVEOLUS AND PALATE IN AFRICAN NATIVES: AN UPDATE ON DEMOGRAPHICS AND MANAGEMENT OUTCOME. Afr J Med Med Sci (2014) 0.75
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A genome-wide association study identifies novel risk loci for type 2 diabetes. Nature (2007) 35.08
A genome-wide association study identifies alleles in FGFR2 associated with risk of sporadic postmenopausal breast cancer. Nat Genet (2007) 22.96
Genome-wide association study of prostate cancer identifies a second risk locus at 8q24. Nat Genet (2007) 21.18
The NCBI dbGaP database of genotypes and phenotypes. Nat Genet (2007) 17.93
Replicating genotype-phenotype associations. Nature (2007) 16.11
New models of collaboration in genome-wide association studies: the Genetic Association Information Network. Nat Genet (2007) 13.76
Demonstrating stratification in a European American population. Nat Genet (2005) 9.49
Genome-wide association studies: potential next steps on a genetic journey. Hum Mol Genet (2008) 7.54
Epidemiological methods for studying genes and environmental factors in complex diseases. Lancet (2001) 5.99
A framework for interpreting genome-wide association studies of psychiatric disorders. Mol Psychiatry (2008) 5.80
Heterogeneity in meta-analyses of genome-wide association investigations. PLoS One (2007) 5.77
Exploiting gene-environment interaction to detect genetic associations. Hum Hered (2007) 5.63
An Icelandic example of the impact of population structure on association studies. Nat Genet (2004) 5.53
Gene-environment interaction in genome-wide association studies. Am J Epidemiol (2008) 3.96
Appropriate data cleaning methods for genome-wide association study. J Hum Genet (2008) 1.92
Application of ancestry informative markers to association studies in European Americans. PLoS Genet (2008) 1.90
Gene-environment interactions for complex traits: definitions, methodological requirements and challenges. Eur J Hum Genet (2008) 1.82
Discovery properties of genome-wide association signals from cumulatively combined data sets. Am J Epidemiol (2009) 1.74
Meta-analysis of genetic association studies: methodologies, between-study heterogeneity and winner's curse. J Hum Genet (2009) 1.46
Less is more, except when less is less: Studying joint effects. Genomics (2008) 1.18
Gene-environment interaction in complex diseases: asthma as an illustrative case. Novartis Found Symp (2008) 0.88
Potential etiologic and functional implications of genome-wide association loci for human diseases and traits. Proc Natl Acad Sci U S A (2009) 54.68
A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants. Science (2007) 43.16
Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes. Nat Genet (2008) 35.06
Heart disease and stroke statistics--2012 update: a report from the American Heart Association. Circulation (2011) 31.98
Heart disease and stroke statistics--2013 update: a report from the American Heart Association. Circulation (2012) 30.79
Heart disease and stroke statistics--2011 update: a report from the American Heart Association. Circulation (2010) 30.07
Genome-wide association study identifies novel breast cancer susceptibility loci. Nature (2007) 29.23
Biological, clinical and population relevance of 95 loci for blood lipids. Nature (2010) 28.21
Heart disease and stroke statistics--2014 update: a report from the American Heart Association. Circulation (2013) 28.02
Sequence variations in PCSK9, low LDL, and protection against coronary heart disease. N Engl J Med (2006) 23.83
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. Nat Genet (2010) 23.08
A genome-wide association study identifies alleles in FGFR2 associated with risk of sporadic postmenopausal breast cancer. Nat Genet (2007) 22.96
Six new loci associated with body mass index highlight a neuronal influence on body weight regulation. Nat Genet (2008) 22.35
Genome-wide association study of prostate cancer identifies a second risk locus at 8q24. Nat Genet (2007) 21.18
A common allele on chromosome 9 associated with coronary heart disease. Science (2007) 20.37
Hundreds of variants clustered in genomic loci and biological pathways affect human height. Nature (2010) 20.01
The NCBI dbGaP database of genotypes and phenotypes. Nat Genet (2007) 17.93
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. Nat Genet (2010) 17.89
Multiple loci identified in a genome-wide association study of prostate cancer. Nat Genet (2008) 17.65
Evolution and functional impact of rare coding variation from deep sequencing of human exomes. Science (2012) 17.12
Risk alleles for multiple sclerosis identified by a genomewide study. N Engl J Med (2007) 17.06
Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis. Nat Genet (2010) 16.96
Identification of ten loci associated with height highlights new biological pathways in human growth. Nat Genet (2008) 16.25
Prevention of venous thromboembolism: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition). Chest (2008) 16.17
Replicating genotype-phenotype associations. Nature (2007) 16.11
Common variants near MC4R are associated with fat mass, weight and risk of obesity. Nat Genet (2008) 15.94
A common genetic variant is associated with adult and childhood obesity. Science (2006) 14.95
Functional impact of global rare copy number variation in autism spectrum disorders. Nature (2010) 14.66
Population-based resequencing of ANGPTL4 uncovers variations that reduce triglycerides and increase HDL. Nat Genet (2007) 13.78
New models of collaboration in genome-wide association studies: the Genetic Association Information Network. Nat Genet (2007) 13.76
Patterns and rates of exonic de novo mutations in autism spectrum disorders. Nature (2012) 13.71
Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease. Nat Genet (2011) 13.25
Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Nature (2011) 13.25
Intake of sugar-sweetened beverages and weight gain: a systematic review. Am J Clin Nutr (2006) 13.19
Cholinergic nicotinic receptor genes implicated in a nicotine dependence association study targeting 348 candidate genes with 3713 SNPs. Hum Mol Genet (2006) 13.16
Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci. Nat Genet (2008) 12.51
Changes in diet and lifestyle and long-term weight gain in women and men. N Engl J Med (2011) 12.29
Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study. Lancet (2012) 12.10
Prevention of venous thromboembolism: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy. Chest (2004) 11.84
Sugar-sweetened beverages, weight gain, and incidence of type 2 diabetes in young and middle-aged women. JAMA (2004) 11.69
Genome-wide association study of blood pressure and hypertension. Nat Genet (2009) 11.54
Diabetes in Asia: epidemiology, risk factors, and pathophysiology. JAMA (2009) 11.52
The genetic association database. Nat Genet (2004) 11.29
Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes. Nat Genet (2012) 11.09
Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease. Nat Genet (2008) 10.87
Common variants on chromosomes 2q35 and 16q12 confer susceptibility to estrogen receptor-positive breast cancer. Nat Genet (2007) 10.81
Admixture mapping identifies 8q24 as a prostate cancer risk locus in African-American men. Proc Natl Acad Sci U S A (2006) 10.32
A prospective study of sleep duration and coronary heart disease in women. Arch Intern Med (2003) 9.24
The role of vitamin D and calcium in type 2 diabetes. A systematic review and meta-analysis. J Clin Endocrinol Metab (2007) 8.91
Fruit and vegetable intake and risk of major chronic disease. J Natl Cancer Inst (2004) 8.77
From vulnerable plaque to vulnerable patient: a call for new definitions and risk assessment strategies: Part I. Circulation (2003) 8.61
Genome partitioning of genetic variation for complex traits using common SNPs. Nat Genet (2011) 8.57
Sugar-sweetened beverages and risk of metabolic syndrome and type 2 diabetes: a meta-analysis. Diabetes Care (2010) 8.52
Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium: Design of prospective meta-analyses of genome-wide association studies from 5 cohorts. Circ Cardiovasc Genet (2009) 8.42
A multistage genome-wide association study in breast cancer identifies two new risk alleles at 1p11.2 and 14q24.1 (RAD51L1). Nat Genet (2009) 8.39
Large-scale genotyping identifies 41 new loci associated with breast cancer risk. Nat Genet (2013) 8.24
Common variants on chromosome 6p22.1 are associated with schizophrenia. Nature (2009) 8.12
Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs. Nat Genet (2013) 8.02
Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution. Nat Genet (2010) 7.94
Interferon regulatory factor 6 (IRF6) gene variants and the risk of isolated cleft lip or palate. N Engl J Med (2004) 7.91
Novel genes identified in a high-density genome wide association study for nicotine dependence. Hum Mol Genet (2006) 7.90
Genetic epidemiology of COPD (COPDGene) study design. COPD (2010) 7.67
Common variants on chromosome 5p12 confer susceptibility to estrogen receptor-positive breast cancer. Nat Genet (2008) 7.65
Large-scale association analysis identifies new risk loci for coronary artery disease. Nat Genet (2012) 7.59
How to interpret a genome-wide association study. JAMA (2008) 7.54
Plasma adiponectin levels and risk of myocardial infarction in men. JAMA (2004) 7.46
Short sleep duration and weight gain: a systematic review. Obesity (Silver Spring) (2008) 7.40
A prospective study of self-reported sleep duration and incident diabetes in women. Diabetes Care (2003) 7.40
Common variants in the GDF5-UQCC region are associated with variation in human height. Nat Genet (2008) 7.31
Concept, design and implementation of a cardiovascular gene-centric 50 k SNP array for large-scale genomic association studies. PLoS One (2008) 7.16
The 8q24 cancer risk variant rs6983267 shows long-range interaction with MYC in colorectal cancer. Nat Genet (2009) 6.99
dbNSFP: a lightweight database of human nonsynonymous SNPs and their functional predictions. Hum Mutat (2011) 6.97
Diet quality and major chronic disease risk in men and women: moving toward improved dietary guidance. Am J Clin Nutr (2002) 6.96
Sugar-sweetened beverages, obesity, type 2 diabetes mellitus, and cardiovascular disease risk. Circulation (2010) 6.86
The ClinSeq Project: piloting large-scale genome sequencing for research in genomic medicine. Genome Res (2009) 6.83
Variants in nicotinic receptors and risk for nicotine dependence. Am J Psychiatry (2008) 6.73
Comparison of abdominal adiposity and overall obesity in predicting risk of type 2 diabetes among men. Am J Clin Nutr (2005) 6.67
Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge. Nat Genet (2010) 6.66