PubRank

Keiyo Takubo

Author PubWeight™ 73.30‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Tie2/angiopoietin-1 signaling regulates hematopoietic stem cell quiescence in the bone marrow niche. Cell 2004 12.67
2 Reactive oxygen species act through p38 MAPK to limit the lifespan of hematopoietic stem cells. Nat Med 2006 7.62
3 Regulation of oxidative stress by ATM is required for self-renewal of haematopoietic stem cells. Nature 2004 7.21
4 Foxo3a is essential for maintenance of the hematopoietic stem cell pool. Cell Stem Cell 2007 5.94
5 Thrombopoietin/MPL signaling regulates hematopoietic stem cell quiescence and interaction with the osteoblastic niche. Cell Stem Cell 2007 4.31
6 Metabolic regulation of hematopoietic stem cells in the hypoxic niche. Cell Stem Cell 2011 3.05
7 M-CSF inhibition selectively targets pathological angiogenesis and lymphangiogenesis. J Exp Med 2009 2.29
8 Fbxw7 acts as a critical fail-safe against premature loss of hematopoietic stem cells and development of T-ALL. Genes Dev 2008 2.12
9 Regulation of reactive oxygen species by Atm is essential for proper response to DNA double-strand breaks in lymphocytes. J Immunol 2007 1.62
10 Hypoxia disrupts the barrier function of neural blood vessels through changes in the expression of claudin-5 in endothelial cells. Am J Pathol 2007 1.54
11 Bone marrow long label-retaining cells reside in the sinusoidal hypoxic niche. Biochem Biophys Res Commun 2007 1.45
12 Reactive oxygen species induce chondrocyte hypertrophy in endochondral ossification. J Exp Med 2007 1.16
13 Cadherin-based adhesion is a potential target for niche manipulation to protect hematopoietic stem cells in adult bone marrow. Cell Stem Cell 2010 1.14
14 Haploinsufficiency of SAMD9L, an endosome fusion facilitator, causes myeloid malignancies in mice mimicking human diseases with monosomy 7. Cancer Cell 2013 1.14
15 A germ cell-specific gene, Prmt5, works in somatic cell reprogramming. J Biol Chem 2011 1.08
16 Craniofacial malformation in R-spondin2 knockout mice. Biochem Biophys Res Commun 2009 1.05
17 Ataxia-telangiectasia mutated (ATM) deficiency decreases reprogramming efficiency and leads to genomic instability in iPS cells. Biochem Biophys Res Commun 2011 1.01
18 Telomerase reverse transcriptase protects ATM-deficient hematopoietic stem cells from ROS-induced apoptosis through a telomere-independent mechanism. Blood 2011 1.00
19 Identification of stem cells during prepubertal spermatogenesis via monitoring of nucleostemin promoter activity. Stem Cells 2008 0.99
20 von Hippel-Lindau protein regulates transition from the fetal to the adult circulatory system in retina. Development 2010 0.99
21 A quantitative matrigel assay for assessing repopulating capacity of prostate stem cells. Biochem Biophys Res Commun 2005 0.98
22 The IL-2/CD25 axis maintains distinct subsets of chronic myeloid leukemia-initiating cells. Blood 2014 0.96
23 Dynamic regulation of Th17 differentiation by oxygen concentrations. Int Immunol 2011 0.93
24 Ex vivo maintenance of hematopoietic stem cells by quiescence induction through Fbxw7α overexpression. Blood 2010 0.89
25 Prostaglandin E(2) regulates murine hematopoietic stem/progenitor cells directly via EP4 receptor and indirectly through mesenchymal progenitor cells. Blood 2013 0.88
26 Optimal ratio of transcription factors for somatic cell reprogramming. J Biol Chem 2012 0.88
27 Reconstitution activity of hypoxic cultured human cord blood CD34-positive cells in NOG mice. Biochem Biophys Res Commun 2008 0.86
28 Hemp, an mbt domain-containing protein, plays essential roles in hematopoietic stem cell function and skeletal formation. Proc Natl Acad Sci U S A 2011 0.86
29 Megakaryocytes are essential for HSC quiescence through the production of thrombopoietin. Biochem Biophys Res Commun 2014 0.86
30 Isolation and function of mouse tissue resident vascular precursors marked by myelin protein zero. J Exp Med 2011 0.83
31 Induction of pluripotent stem cells from primordial germ cells by single reprogramming factors. Stem Cells 2013 0.82
32 Neovascular niche for human myeloma cells in immunodeficient mouse bone. PLoS One 2012 0.81
33 R-spondins/Lgrs expression in tooth development. Dev Dyn 2014 0.80
34 TAK1 (MAP3K7) signaling regulates hematopoietic stem cells through TNF-dependent and -independent mechanisms. PLoS One 2012 0.80
35 Tet2-mutated myeloid progenitors possess aberrant in vitro self-renewal capacity. Blood 2014 0.79
36 Tracing the conversion process from primordial germ cells to pluripotent stem cells in mice. Biol Reprod 2012 0.78
37 Acquisition of G₀ state by CD34-positive cord blood cells after bone marrow transplantation. Exp Hematol 2010 0.78
38 Brain-specific expression of vascular endothelial growth factor 146 correlates with the blood-brain barrier induction in quail embryos. Dev Neurosci 2008 0.75
39 Correction: CLEC-2 in megakaryocytes is critical for maintenance of hematopoietic stem cells in the bone marrow. J Exp Med 2015 0.75
40 Proliferation following tetraploidization regulates the size and number of erythrocytes in the blood flow during medaka development, as revealed by the abnormal karyotype of erythrocytes in the medaka TFDP1 mutant. Dev Dyn 2015 0.75
41 [Homeostatic regulation of hematopoiesis by the hematopoietic stem cell niche]. Seikagaku 2014 0.75
42 [Regulation of hematopoietic stem cells by oxygen metabolism]. Rinsho Ketsueki 2010 0.75