| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity.
|
Science
|
2007
|
37.88
|
|
2
|
Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes.
|
Nat Genet
|
2008
|
35.06
|
|
3
|
Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes.
|
Science
|
2007
|
32.97
|
|
4
|
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index.
|
Nat Genet
|
2010
|
23.08
|
|
5
|
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk.
|
Nat Genet
|
2010
|
17.89
|
|
6
|
Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis.
|
Nat Genet
|
2010
|
16.96
|
|
7
|
Common variants near MC4R are associated with fat mass, weight and risk of obesity.
|
Nat Genet
|
2008
|
15.94
|
|
8
|
Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants.
|
Nat Genet
|
2007
|
12.62
|
|
9
|
Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.
|
Nat Genet
|
2012
|
11.09
|
|
10
|
Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution.
|
Nat Genet
|
2010
|
7.94
|
|
11
|
Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution.
|
PLoS Genet
|
2009
|
5.81
|
|
12
|
Common variants near ATM are associated with glycemic response to metformin in type 2 diabetes.
|
Nat Genet
|
2010
|
4.42
|
|
13
|
Combining information from common type 2 diabetes risk polymorphisms improves disease prediction.
|
PLoS Med
|
2006
|
3.75
|
|
14
|
Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals.
|
PLoS Genet
|
2012
|
3.21
|
|
15
|
Common variants associated with plasma triglycerides and risk for coronary artery disease.
|
Nat Genet
|
2013
|
2.92
|
|
16
|
Variants in ADCY5 and near CCNL1 are associated with fetal growth and birth weight.
|
Nat Genet
|
2010
|
2.30
|
|
17
|
Interactions of dietary whole-grain intake with fasting glucose- and insulin-related genetic loci in individuals of European descent: a meta-analysis of 14 cohort studies.
|
Diabetes Care
|
2010
|
2.14
|
|
18
|
New loci associated with birth weight identify genetic links between intrauterine growth and adult height and metabolism.
|
Nat Genet
|
2012
|
1.90
|
|
19
|
A genome-wide association search for type 2 diabetes genes in African Americans.
|
PLoS One
|
2012
|
1.72
|
|
20
|
Genetic evidence that raised sex hormone binding globulin (SHBG) levels reduce the risk of type 2 diabetes.
|
Hum Mol Genet
|
2009
|
1.61
|
|
21
|
Type 2 diabetes risk alleles are associated with reduced size at birth.
|
Diabetes
|
2009
|
1.58
|
|
22
|
Type 2 diabetes TCF7L2 risk genotypes alter birth weight: a study of 24,053 individuals.
|
Am J Hum Genet
|
2007
|
1.52
|
|
23
|
The plasma cell signature in autoimmune disease.
|
Arthritis Rheumatol
|
2014
|
1.47
|
|
24
|
Association between the T-381C polymorphism of the brain natriuretic peptide gene and risk of type 2 diabetes in human populations.
|
Hum Mol Genet
|
2007
|
1.40
|
|
25
|
Evidence for linkage of stature to chromosome 3p26 in a large U.K. Family data set ascertained for type 2 diabetes.
|
Am J Hum Genet
|
2001
|
1.32
|
|
26
|
Genetic variations in the gene encoding TFAP2B are associated with type 2 diabetes mellitus.
|
J Hum Genet
|
2005
|
1.21
|
|
27
|
Meta-analysis and functional effects of the SLC30A8 rs13266634 polymorphism on isolated human pancreatic islets.
|
Mol Genet Metab
|
2010
|
1.10
|
|
28
|
Variation within the gene encoding the upstream stimulatory factor 1 does not influence susceptibility to type 2 diabetes in samples from populations with replicated evidence of linkage to chromosome 1q.
|
Diabetes
|
2006
|
1.04
|
|
29
|
Meta-analysis investigating associations between healthy diet and fasting glucose and insulin levels and modification by loci associated with glucose homeostasis in data from 15 cohorts.
|
Am J Epidemiol
|
2012
|
1.03
|
|
30
|
Young-onset type 2 diabetes families are the major contributors to genetic loci in the Diabetes UK Warren 2 genome scan and identify putative novel loci on chromosomes 8q21, 21q22, and 22q11.
|
Diabetes
|
2003
|
1.03
|
|
31
|
Large-scale analysis of the relationship between CYP11A promoter variation, polycystic ovarian syndrome, and serum testosterone.
|
J Clin Endocrinol Metab
|
2004
|
1.01
|
|
32
|
Sequencing of candidate genes selected by beta cell experts in monogenic diabetes of unknown aetiology.
|
JOP
|
2010
|
0.98
|
|
33
|
Analysis of multiple data sets reveals no association between the insulin gene variable number tandem repeat element and polycystic ovary syndrome or related traits.
|
J Clin Endocrinol Metab
|
2005
|
0.96
|
|
34
|
Linkage disequilibrium mapping of the replicated type 2 diabetes linkage signal on chromosome 1q.
|
Diabetes
|
2009
|
0.95
|
|
35
|
Evidence from a large U.K. family collection that genes influencing age of onset of type 2 diabetes map to chromosome 12p and to the MODY3/NIDDM2 locus on 12q24.
|
Diabetes
|
2004
|
0.94
|
|
36
|
Large-scale association analysis of TNF/LTA gene region polymorphisms in type 2 diabetes.
|
BMC Med Genet
|
2010
|
0.90
|
|
37
|
Higher magnesium intake is associated with lower fasting glucose and insulin, with no evidence of interaction with select genetic loci, in a meta-analysis of 15 CHARGE Consortium Studies.
|
J Nutr
|
2013
|
0.88
|
|
38
|
Common variation in the LMNA gene (encoding lamin A/C) and type 2 diabetes: association analyses in 9,518 subjects.
|
Diabetes
|
2007
|
0.84
|
|
39
|
Low frequency variants in the exons only encoding isoform A of HNF1A do not contribute to susceptibility to type 2 diabetes.
|
PLoS One
|
2009
|
0.83
|
|
40
|
Relationship between E23K (an established type II diabetes-susceptibility variant within KCNJ11), polycystic ovary syndrome and androgen levels.
|
Eur J Hum Genet
|
2007
|
0.81
|
|
41
|
Cell-surface and cytokine biomarkers in autoimmune and inflammatory diseases.
|
Drug Discov Today
|
2006
|
0.81
|
|
42
|
Family-based analysis of tumor necrosis factor and lymphotoxin-alpha tag polymorphisms with type 1 diabetes in the population of South Croatia.
|
Hum Immunol
|
2009
|
0.78
|
|
43
|
Management of symptomatic esophageal involvement with lichen planus.
|
J Clin Gastroenterol
|
2009
|
0.75
|