PubRank

Inês Barroso

Author PubWeight™ 466.26‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity. Science 2007 37.88
2 Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes. Nat Genet 2008 35.06
3 Biological, clinical and population relevance of 95 loci for blood lipids. Nature 2010 28.21
4 Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. Nat Genet 2010 23.08
5 Six new loci associated with body mass index highlight a neuronal influence on body weight regulation. Nat Genet 2008 22.35
6 Hundreds of variants clustered in genomic loci and biological pathways affect human height. Nature 2010 20.01
7 New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. Nat Genet 2010 17.89
8 Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis. Nat Genet 2010 16.96
9 Genome-wide association analysis identifies 20 loci that influence adult height. Nat Genet 2008 16.92
10 Common variants near MC4R are associated with fat mass, weight and risk of obesity. Nat Genet 2008 15.94
11 Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Nature 2011 13.25
12 Genome-wide association study identifies eight loci associated with blood pressure. Nat Genet 2009 12.44
13 Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls. Nature 2010 12.27
14 Variants in MTNR1B influence fasting glucose levels. Nat Genet 2008 10.85
15 The obesity-associated FTO gene encodes a 2-oxoglutarate-dependent nucleic acid demethylase. Science 2007 9.86
16 Meta-analysis and imputation refines the association of 15q25 with smoking quantity. Nat Genet 2010 8.55
17 Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution. Nat Genet 2010 7.94
18 Large-scale association analysis identifies new risk loci for coronary artery disease. Nat Genet 2012 7.59
19 Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge. Nat Genet 2010 6.66
20 LDL-cholesterol concentrations: a genome-wide association study. Lancet 2008 6.44
21 The metabochip, a custom genotyping array for genetic studies of metabolic, cardiovascular, and anthropometric traits. PLoS Genet 2012 6.15
22 The architecture of gene regulatory variation across multiple human tissues: the MuTHER study. PLoS Genet 2011 5.95
23 Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution. PLoS Genet 2009 5.81
24 Candidate causal regulatory effects by integration of expression QTLs with complex trait genetic associations. PLoS Genet 2010 4.95
25 Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways. Nat Genet 2012 4.73
26 Meta-analysis of genome-wide scans for human adult stature identifies novel Loci and associations with measures of skeletal frame size. PLoS Genet 2009 4.24
27 Genome-wide association study identifies five loci associated with lung function. Nat Genet 2009 4.10
28 Genetic variants influencing circulating lipid levels and risk of coronary artery disease. Arterioscler Thromb Vasc Biol 2010 4.08
29 Common variants at 10 genomic loci influence hemoglobin A₁(C) levels via glycemic and nonglycemic pathways. Diabetes 2010 4.07
30 The UK10K project identifies rare variants in health and disease. Nature 2015 3.89
31 Common variants in WFS1 confer risk of type 2 diabetes. Nat Genet 2007 3.58
32 A family with severe insulin resistance and diabetes due to a mutation in AKT2. Science 2004 3.54
33 Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure. Nat Genet 2011 3.40
34 Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies. Nat Genet 2010 3.37
35 Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture. Nat Genet 2013 3.25
36 Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals. PLoS Genet 2012 3.21
37 Genetic variation in LIN28B is associated with the timing of puberty. Nat Genet 2009 3.09
38 Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function. Nat Genet 2011 3.03
39 Common variants associated with plasma triglycerides and risk for coronary artery disease. Nat Genet 2013 2.92
40 Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits. PLoS Genet 2013 2.83
41 Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile. Nat Genet 2011 2.73
42 Genomics: ENCODE explained. Nature 2012 2.62
43 A genome-wide association meta-analysis identifies new childhood obesity loci. Nat Genet 2012 2.60
44 Clinical and molecular genetic spectrum of congenital deficiency of the leptin receptor. N Engl J Med 2007 2.56
45 Detailed physiologic characterization reveals diverse mechanisms for novel genetic Loci regulating glucose and insulin metabolism in humans. Diabetes 2010 2.44
46 Genetic factors in type 2 diabetes: the end of the beginning? Science 2005 2.37
47 Genome-wide association identifies nine common variants associated with fasting proinsulin levels and provides new insights into the pathophysiology of type 2 diabetes. Diabetes 2011 2.21
48 TCF7L2 polymorphisms modulate proinsulin levels and beta-cell function in a British Europid population. Diabetes 2007 2.20
49 Rare MTNR1B variants impairing melatonin receptor 1B function contribute to type 2 diabetes. Nat Genet 2012 2.15
50 Effect of five genetic variants associated with lung function on the risk of chronic obstructive lung disease, and their joint effects on lung function. Am J Respir Crit Care Med 2011 2.07
51 The genetics of obesity: FTO leads the way. Trends Genet 2010 1.90
52 Comment on "A common genetic variant is associated with adult and childhood obesity". Science 2007 1.86
53 Partial lipodystrophy and insulin resistant diabetes in a patient with a homozygous nonsense mutation in CIDEC. EMBO Mol Med 2009 1.80
54 Mosaic overgrowth with fibroadipose hyperplasia is caused by somatic activating mutations in PIK3CA. Nat Genet 2012 1.74
55 Genome-wide SNP and CNV analysis identifies common and low-frequency variants associated with severe early-onset obesity. Nat Genet 2013 1.72
56 A genome-wide association search for type 2 diabetes genes in African Americans. PLoS One 2012 1.72
57 Genetic evidence that raised sex hormone binding globulin (SHBG) levels reduce the risk of type 2 diabetes. Hum Mol Genet 2009 1.61
58 Perilipin deficiency and autosomal dominant partial lipodystrophy. N Engl J Med 2011 1.61
59 Underlying genetic models of inheritance in established type 2 diabetes associations. Am J Epidemiol 2009 1.60
60 Non-DNA binding, dominant-negative, human PPARgamma mutations cause lipodystrophic insulin resistance. Cell Metab 2006 1.57
61 Digenic inheritance of severe insulin resistance in a human pedigree. Nat Genet 2002 1.36
62 Genome-wide meta-analysis of observational studies shows common genetic variants associated with macronutrient intake. Am J Clin Nutr 2013 1.35
63 Mendelian randomization study of B-type natriuretic peptide and type 2 diabetes: evidence of causal association from population studies. PLoS Med 2011 1.30
64 Detailed investigation of the role of common and low-frequency WFS1 variants in type 2 diabetes risk. Diabetes 2009 1.25
65 Genome-wide association studies and type 2 diabetes. Brief Funct Genomics 2011 1.24
66 A truncation mutation in TBC1D4 in a family with acanthosis nigricans and postprandial hyperinsulinemia. Proc Natl Acad Sci U S A 2009 1.23
67 A comprehensive evaluation of potential lung function associated genes in the SpiroMeta general population sample. PLoS One 2011 1.13
68 PPARGC1A genotype (Gly482Ser) predicts exceptional endurance capacity in European men. J Appl Physiol (1985) 2005 1.12
69 The emerging use of zebrafish to model metabolic disease. Dis Model Mech 2013 1.09
70 Whole genome-amplified DNA: insights and imputation. Nat Methods 2008 1.02
71 Human SH2B1 mutations are associated with maladaptive behaviors and obesity. J Clin Invest 2012 1.01
72 Hypomorphism in human NSMCE2 linked to primordial dwarfism and insulin resistance. J Clin Invest 2014 0.98
73 Analysis of genetic variation in Akt2/PKB-beta in severe insulin resistance, lipodystrophy, type 2 diabetes, and related metabolic phenotypes. Diabetes 2007 0.98
74 Evaluating the role of LPIN1 variation in insulin resistance, body weight, and human lipodystrophy in U.K. Populations. Diabetes 2008 0.97
75 Genetic variants in human sterol regulatory element binding protein-1c in syndromes of severe insulin resistance and type 2 diabetes. Diabetes 2004 0.94
76 Lamin A/C polymorphisms, type 2 diabetes, and the metabolic syndrome: case-control and quantitative trait studies. Diabetes 2007 0.90
77 Differentiating campomelic dysplasia from Cumming syndrome. Am J Med Genet A 2005 0.89
78 Genome-wide meta-analysis of common variant differences between men and women. Hum Mol Genet 2012 0.88
79 No interactions between previously associated 2-hour glucose gene variants and physical activity or BMI on 2-hour glucose levels. Diabetes 2012 0.86
80 Variation in the eNOS gene modifies the association between total energy expenditure and glucose intolerance. Diabetes 2005 0.84
81 Early Diagnosis of Werner's Syndrome Using Exome-Wide Sequencing in a Single, Atypical Patient. Front Endocrinol (Lausanne) 2011 0.84
82 The Gly482Ser genotype at the PPARGC1A gene and elevated blood pressure: a meta-analysis involving 13,949 individuals. J Appl Physiol (1985) 2008 0.81
83 PGC-1alpha genotype modifies the association of volitional energy expenditure with [OV0312]O2max. Med Sci Sports Exerc 2003 0.79
84 Complex disease: pleiotropic gene effects in obesity and type 2 diabetes. Eur J Hum Genet 2005 0.78
85 Functional characterization of obesity-associated variants involving the α and β isoforms of human SH2B1. Endocrinology 2014 0.77
86 Habitual energy expenditure modifies the association between NOS3 gene polymorphisms and blood pressure. Am J Hypertens 2008 0.77
87 Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study. PLoS Genet 2016 0.75
88 Correction: Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults. PLoS Genet 2017 0.75
89 Corrigendum: Integrative genomic analysis implicates limited peripheral adipose storage capacity in the pathogenesis of human insulin resistance. Nat Genet 2017 0.75