Published in Angiology on April 02, 2008
Inflammaging and anti-inflammaging: a systemic perspective on aging and longevity emerged from studies in humans. Mech Ageing Dev (2006) 5.61
Diagnostic potential of circulating miR-499-5p in elderly patients with acute non ST-elevation myocardial infarction. Int J Cardiol (2012) 3.20
Polymorphic variants of insulin-like growth factor I (IGF-I) receptor and phosphoinositide 3-kinase genes affect IGF-I plasma levels and human longevity: cues for an evolutionarily conserved mechanism of life span control. J Clin Endocrinol Metab (2003) 2.40
Early aggressive versus initially conservative treatment in elderly patients with non-ST-segment elevation acute coronary syndrome: a randomized controlled trial. JACC Cardiovasc Interv (2012) 1.83
Chronic inflammation and the effect of IGF-I on muscle strength and power in older persons. Am J Physiol Endocrinol Metab (2002) 1.76
Strikingly higher frequency in centenarians and twins of mtDNA mutation causing remodeling of replication origin in leukocytes. Proc Natl Acad Sci U S A (2003) 1.56
Genes involved in immune response/inflammation, IGF1/insulin pathway and response to oxidative stress play a major role in the genetics of human longevity: the lesson of centenarians. Mech Ageing Dev (2005) 1.49
An APOE haplotype associated with decreased ε4 expression increases the risk of late onset Alzheimer's disease. J Alzheimers Dis (2011) 1.45
Age-related differences in the expression of circulating microRNAs: miR-21 as a new circulating marker of inflammaging. Mech Ageing Dev (2012) 1.19
Impact of telemonitoring at home on the management of elderly patients with congestive heart failure. J Telemed Telecare (2008) 1.17
MiR-146a as marker of senescence-associated pro-inflammatory status in cells involved in vascular remodelling. Age (Dordr) (2012) 1.13
Leukocyte telomere shortening in elderly Type2DM patients with previous myocardial infarction. Atherosclerosis (2009) 1.09
Genetic polymorphism in long-lived people: cues for the presence of an insulin/IGF-pathway-dependent network affecting human longevity. Mol Cell Endocrinol (2008) 1.09
Evidence for sub-haplogroup h5 of mitochondrial DNA as a risk factor for late onset Alzheimer's disease. PLoS One (2010) 1.06
-174 G>C polymorphism of interleukin 6 gene promoter affects interleukin 6 serum level in patients with colorectal cancer. Clin Cancer Res (2003) 1.05
The G/C915 polymorphism of transforming growth factor beta1 is associated with human longevity: a study in Italian centenarians. Aging Cell (2004) 1.04
Retention of the p53 codon 72 arginine allele is associated with a reduction of disease-free and overall survival in arginine/proline heterozygous breast cancer patients. Clin Cancer Res (2003) 1.04
Gender specific association of genetic variation in peroxisome proliferator-activated receptor (PPAR)gamma-2 with longevity. Exp Gerontol (2004) 1.03
Paraoxonase polymorphisms PON1 192 and 55 and longevity in Italian centenarians and Irish nonagenarians. A pooled analysis. Exp Gerontol (2004) 1.01
Interleukin-6 gene alleles affect the risk of Alzheimer's disease and levels of the cytokine in blood and brain. Neurobiol Aging (2003) 1.01
Effects of donepezil, galantamine and rivastigmine in 938 Italian patients with Alzheimer's disease: a prospective, observational study. CNS Drugs (2010) 0.97
What studies on human longevity tell us about the risk for cancer in the oldest old: data and hypotheses on the genetics and immunology of centenarians. Exp Gerontol (2002) 0.97
Cholesteryl ester transfer protein (CETP) I405V polymorphism and longevity in Italian centenarians. Mech Ageing Dev (2005) 0.96
p53 codon 72 genotype affects apoptosis by cytosine arabinoside in blood leukocytes. Biochem Biophys Res Commun (2002) 0.95
Is chronic inflammation a determinant of blood pressure in the elderly? Am J Hypertens (2003) 0.94
Centenarians as super-controls to assess the biological relevance of genetic risk factors for common age-related diseases: a proof of principle on type 2 diabetes. Aging (Albany NY) (2013) 0.94
The -174G/C polymorphism of IL-6 is useful to screen old subjects at risk for atherosclerosis or to reach successful ageing. Exp Gerontol (2004) 0.92
The role of IL-1 gene cluster in longevity: a study in Italian population. Mech Ageing Dev (2003) 0.92
Allele frequencies of +874T-->A single nucleotide polymorphism at the first intron of interferon-gamma gene in a group of Italian centenarians. Exp Gerontol (2002) 0.92
Genetic analysis of Paraoxonase (PON1) locus reveals an increased frequency of Arg192 allele in centenarians. Eur J Hum Genet (2002) 0.91
Human longevity within an evolutionary perspective: the peculiar paradigm of a post-reproductive genetics. Exp Gerontol (2007) 0.91
Conventional and novel diagnostic biomarkers of acute myocardial infarction: a promising role for circulating microRNAs. Biomarkers (2013) 0.90
Paraoxonase 1: genetics and activities during aging. Rejuvenation Res (2008) 0.89
Telomere/Telomerase system: a new target of statins pleiotropic effect? Curr Vasc Pharmacol (2012) 0.89
A polymorphism of the YTHDF2 gene (1p35) located in an Alu-rich genomic domain is associated with human longevity. J Gerontol A Biol Sci Med Sci (2006) 0.89
Tumor necrosis factor-alpha gene -308G>A polymorphism is associated with ST-elevation myocardial infarction and with high plasma levels of biochemical ischemia markers. Coron Artery Dis (2005) 0.88
Circulating microRNAs (miRs) for diagnosing acute myocardial infarction: an exciting challenge. Int J Cardiol (2012) 0.88
Genetic polymorphisms of inflammatory cytokines and myocardial infarction in the elderly. Mech Ageing Dev (2006) 0.86
An allele of HRAS1 3'variable number of tandem repeats is a frailty allele: implication for an evolutionarily-conserved pathway involved in longevity. Gene (2002) 0.85
Predicting microRNA modulation in human prostate cancer using a simple String IDentifier (SID1.0). J Biomed Inform (2011) 0.85
The interleukin-6 -174 G>C promoter polymorphism is associated with a higher risk of death after an acute coronary syndrome in male elderly patients. Int J Cardiol (2005) 0.85
Remodelling of biological parameters during human ageing: evidence for complex regulation in longevity and in type 2 diabetes. Age (Dordr) (2011) 0.85
Paraoxonase activity and genotype predispose to successful aging. J Gerontol A Biol Sci Med Sci (2006) 0.84
Mismatch repair system and aging: microsatellite instability in peripheral blood cells from differently aged participants. J Gerontol A Biol Sci Med Sci (2005) 0.83
Lipoxygenase inhibitors for cancer prevention: promises and risks. Curr Pharm Des (2010) 0.83
A novel mitochondrial DNA-like sequence insertion polymorphism in Intron I of the FOXO1A gene. Gene (2004) 0.82
One-year mortality in elderly adults with non-ST-elevation acute coronary syndrome: effect of diabetic status and admission hyperglycemia. J Am Geriatr Soc (2014) 0.82
Aged-related increase of high sensitive Troponin T and its implication in acute myocardial infarction diagnosis of elderly patients. Mech Ageing Dev (2012) 0.82
mRNAs and miRNAs profiling of mesenchymal stem cells derived from amniotic fluid and skin: the double face of the coin. Cell Tissue Res (2013) 0.81
Cellular senescence in cardiovascular diseases: potential age-related mechanisms and implications for treatment. Curr Pharm Des (2013) 0.81
Chlamydia pneumoniae seropositivity and cardiovascular risk factors: The InCHIANTI Study. J Am Geriatr Soc (2004) 0.80
Endothelial Cell Senescence and Inflammaging: MicroRNAs as Biomarkers and Innovative Therapeutic Tools. Curr Drug Targets (2016) 0.80
Causes of death in patients ≥75 years of age with non-ST-segment elevation acute coronary syndrome. Am J Cardiol (2013) 0.80
Combination of biomarkers to predict mortality in elderly patients with myocardial infarction. Mech Ageing Dev (2008) 0.80
Prevention of cardiovascular events in early menopause: a possible role for hormone replacement therapy. Int J Cardiol (2008) 0.80
The p53 codon 72 (Arg72Pro) polymorphism is associated with the degree of insulin resistance in type 2 diabetic subjects: a cross-sectional study. Acta Diabetol (2012) 0.80
Technological approaches to remote monitoring of elderly people in cardiology: a usability perspective. Int J Telemed Appl (2012) 0.78
Genome-wide association studies: is there a genotype for cognitive decline in older persons with type 2 diabetes? Curr Pharm Des (2011) 0.78
The MALVA (MAntova LongeVA) study: an investigation on people 98 years of age and over in a province of Northern Italy. Exp Gerontol (2003) 0.78
Paraoxonase-1 55 LL Genotype Is Associated with No ST-Elevation Myocardial Infarction and with High Levels of Myoglobin. J Lipids (2012) 0.77
[The role of molecular biology in the diagnosis and treatment of cardiovascular diseases]. G Ital Cardiol (Rome) (2010) 0.77
Platelet nitric oxide production and IR: relation with obesity and hypertriglyceridemia. Nutr Metab Cardiovasc Dis (2007) 0.77
Paraoxonase2 C311S polymorphism and low levels of HDL contribute to a higher mortality risk after acute myocardial infarction in elderly patients. Mol Genet Metab (2009) 0.76
Failure to replicate an association of rs5984894 SNP in the PCDH11X gene in a collection of 1,222 Alzheimer's disease affected patients. J Alzheimers Dis (2010) 0.76
Frailty and safety: the example of diabetes. Drug Saf (2012) 0.76
Myocardial bridging: A 'forgotten' cause of acute coronary syndrome - a case report. Int J Angiol (2007) 0.75
The Pro/Pro genotype of the p53 codon 72 polymorphism modulates PAI-1 plasma levels in ageing. Mech Ageing Dev (2009) 0.75
Genes of human longevity: an endless quest? Curr Vasc Pharmacol (2014) 0.75
Pulmonary embolism with minimal D-dimer increase - disagreement between clinic and laboratory: case report. J Biol Regul Homeost Agents (2010) 0.75
The PON1192RR genotype is associated with a higher prevalence of arterial hypertension. J Hypertens (2006) 0.75
Progress of research on microRNAs with diagnostic value in asbestos exposure: A call for method standardization. Biosci Trends (2017) 0.75
[Dronedarone: a real innovation or a mere second-best choice? How to find the way among guidelines, regulatory agencies and daily clinical practice]. G Ital Cardiol (Rome) (2012) 0.75
[Treatment of acute coronary syndromes in the elderly: key messages from the Italian Elderly ACS Study]. G Ital Cardiol (Rome) (2012) 0.75
[Tako-tsubo-resembling syndrome with atypical clinical presentation]. G Ital Cardiol (Rome) (2008) 0.75
[Long-term solutions for the continuous post-acute care of the frail elderly in internal medicine]. Ann Ital Med Int (2005) 0.75