Published in J Immunol on April 15, 2008
New insights into the regulation of T cells by gamma(c) family cytokines. Nat Rev Immunol (2009) 5.57
ATP11C is critical for the internalization of phosphatidylserine and differentiation of B lymphocytes. Nat Immunol (2011) 2.21
IL-7 and IL-21 are superior to IL-2 and IL-15 in promoting human T cell-mediated rejection of systemic lymphoma in immunodeficient mice. Blood (2010) 1.29
IL-7 signaling and CD127 receptor regulation in the control of T cell homeostasis. Semin Immunol (2012) 1.27
Modulating T-cell homeostasis with IL-7: preclinical and clinical studies. J Intern Med (2009) 1.14
IL-7 induces expression and activation of integrin α4β7 promoting naive T-cell homing to the intestinal mucosa. Blood (2012) 1.14
T cell factor-1 negatively regulates expression of IL-17 family of cytokines and protects mice from experimental autoimmune encephalomyelitis. J Immunol (2011) 1.08
Cytomegalovirus-induced effector T cells cause endothelial cell damage. Clin Vaccine Immunol (2012) 1.02
Glut1-mediated glucose transport regulates HIV infection. Proc Natl Acad Sci U S A (2012) 1.02
Dual mechanism of impairment of interleukin-7 (IL-7) responses in human immunodeficiency virus infection: decreased IL-7 binding and abnormal activation of the JAK/STAT5 pathway. J Virol (2010) 1.00
Interleukin-7 compartmentalizes its receptor signaling complex to initiate CD4 T lymphocyte response. J Biol Chem (2010) 0.99
Regulatory gene network circuits underlying T cell development from multipotent progenitors. Wiley Interdiscip Rev Syst Biol Med (2011) 0.91
Ets-1 maintains IL-7 receptor expression in peripheral T cells. J Immunol (2010) 0.90
CD40 regulates human dendritic cell-derived IL-7 production that, in turn, contributes to CD8(+) T-cell antigen-specific expansion. Immunol Cell Biol (2008) 0.87
Ephrinb1 and Ephrinb2 are associated with interleukin-7 receptor α and retard its internalization from the cell surface. J Biol Chem (2011) 0.87
Membrane microdomains and cytoskeleton organization shape and regulate the IL-7 receptor signalosome in human CD4 T-cells. J Biol Chem (2013) 0.87
Phenotypical characterization of regulatory T cells in humans and rodents. Clin Exp Immunol (2016) 0.86
IL7Rα contributes to experimental autoimmune encephalomyelitis through altered T cell responses and nonhematopoietic cell lineages. J Immunol (2013) 0.84
Decreased interleukin 7 responsiveness of T lymphocytes in patients with idiopathic CD4 lymphopenia. J Infect Dis (2012) 0.83
Differential response of regulatory and conventional CD4⁺ lymphocytes to CD3 engagement: clues to a possible mechanism of anti-CD3 action? J Immunol (2013) 0.80
Progressive activation of CD127+132- recent thymic emigrants into terminally differentiated CD127-132+ T-cells in HIV-1 infection. PLoS One (2012) 0.79
Establishment and Maintenance of the Human Naïve CD4(+) T-Cell Compartment. Front Pediatr (2016) 0.77
Characteristics of alloreactive T cells measured before renal transplantation. Clin Exp Immunol (2012) 0.77
Selective Sparing of Human Tregs by Pharmacologic Inhibitors of the Phosphatidylinositol 3-Kinase and MEK Pathways. Am J Transplant (2016) 0.75
Efforts of the human immune system to maintain the peripheral CD8+ T cell compartment after childhood thymectomy. Immun Ageing (2016) 0.75
Clinically Relevant Reactivation of Polyomavirus BK (BKPyV) in HLA-A02-Positive Renal Transplant Recipients Is Associated with Impaired Effector-Memory Differentiation of BKPyV-Specific CD8+ T Cells. PLoS Pathog (2016) 0.75
Partial recovery of senescence and differentiation disturbances in CD8(+) T cell effector-memory cells in HIV-1 infection after initiation of anti-retroviral treatment. Clin Exp Immunol (2016) 0.75
Transcriptional regulation of the IL-7Rα gene by dexamethasone and IL-7 in primary human CD8 T cells. Immunogenetics (2016) 0.75
Adjuvant IL-7 potentiates adoptive T cell therapy by amplifying and sustaining polyfunctional antitumor CD4+ T cells. Sci Rep (2017) 0.75
Primary immune responses to human CMV: a critical role for IFN-gamma-producing CD4+ T cells in protection against CMV disease. Blood (2002) 2.83
CD20 deficiency in humans results in impaired T cell-independent antibody responses. J Clin Invest (2009) 2.15
Selective accumulation of differentiated CD8+ T cells specific for respiratory viruses in the human lung. J Exp Med (2005) 2.04
Apoptosis threshold set by Noxa and Mcl-1 after T cell activation regulates competitive selection of high-affinity clones. Immunity (2010) 1.98
Lethal T cell immunodeficiency induced by chronic costimulation via CD27-CD70 interactions. Nat Immunol (2002) 1.97
IL-7 receptor alpha chain expression distinguishes functional subsets of virus-specific human CD8+ T cells. Blood (2005) 1.95
Timing and tuning of CD27-CD70 interactions: the impact of signal strength in setting the balance between adaptive responses and immunopathology. Immunol Rev (2009) 1.90
Emergence of a CD4+CD28- granzyme B+, cytomegalovirus-specific T cell subset after recovery of primary cytomegalovirus infection. J Immunol (2004) 1.89
The Noxa/Mcl-1 axis regulates susceptibility to apoptosis under glucose limitation in dividing T cells. Immunity (2006) 1.86
Hyposplenism: comparison of different methods for determining splenic function. Am J Hematol (2012) 1.69
Expression of the murine CD27 ligand CD70 in vitro and in vivo. J Immunol (2003) 1.66
Human T-cell memory consists mainly of unexpanded clones. Immunol Lett (2010) 1.60
Differential usage of cellular niches by cytomegalovirus versus EBV- and influenza virus-specific CD8+ T cells. J Immunol (2006) 1.55
Idiopathic CD4+ T lymphopenia without autoimmunity or granulomatous disease in the slipstream of RAG mutations. Blood (2011) 1.53
Invasive fungal infection and impaired neutrophil killing in human CARD9 deficiency. Blood (2013) 1.51
Molecular profiling of cytomegalovirus-induced human CD8+ T cell differentiation. J Clin Invest (2010) 1.50
IL-2/anti-IL-2 antibody complexes show strong biological activity by avoiding interaction with IL-2 receptor alpha subunit CD25. Proc Natl Acad Sci U S A (2010) 1.50
CMV-specific CD8+ T-cell function is not impaired in chronic lymphocytic leukemia. Blood (2013) 1.49
Respiratory syncytial virus-specific CD8+ memory T cell responses in elderly persons. J Infect Dis (2005) 1.48
Tumor rejection induced by CD70-mediated quantitative and qualitative effects on effector CD8+ T cell formation. J Exp Med (2004) 1.46
CD27 defines phenotypically and functionally different human NK cell subsets. J Immunol (2008) 1.44
Cytomegalovirus infection reduces telomere length of the circulating T cell pool. J Immunol (2010) 1.42
The size and phenotype of virus-specific T cell populations is determined by repetitive antigenic stimulation and environmental cytokines. J Immunol (2004) 1.41
CD8⁺ T cells with an intraepithelial phenotype upregulate cytotoxic function upon influenza infection in human lung. J Clin Invest (2011) 1.40
CD103 is a marker for alloantigen-induced regulatory CD8+ T cells. J Immunol (2006) 1.33
Clinical and immunologic aspects of cytomegalovirus infection in solid organ transplant recipients. Transplantation (2005) 1.33
IL-15 induces antigen-independent expansion and differentiation of human naive CD8+ T cells in vitro. Blood (2003) 1.26
Human virus-specific CD8+ T cells: diversity specialists. Immunol Rev (2006) 1.24
B cells are crucial for both development and maintenance of the splenic marginal zone. J Immunol (2004) 1.23
IL-21 sustains CD28 expression on IL-15-activated human naive CD8+ T cells. J Immunol (2005) 1.19
Properties of murine (CD8+)CD27- T cells. Eur J Immunol (2005) 1.19
Properties of CD4(+) T cells in human cytomegalovirus infection. Hum Immunol (2004) 1.17
Rapamycin does not induce anergy but inhibits expansion and differentiation of alloreactive human T cells. Transplantation (2006) 1.16
The epidermal growth factor-seven transmembrane (EGF-TM7) receptor CD97 is required for neutrophil migration and host defense. J Immunol (2004) 1.14
CD27-CD70 interactions sensitise naive CD4+ T cells for IL-12-induced Th1 cell development. Int Immunol (2007) 1.14
Immune activation modulates hematopoiesis through interactions between CD27 and CD70. Nat Immunol (2005) 1.11
Absence of circulating natural killer and primed CD8+ cells in life-threatening varicella. J Infect Dis (2004) 1.09
Common gamma chain cytokines: dissidence in the details. Immunol Lett (2006) 1.08
A fingerprint left by cytomegalovirus infection in the human T cell compartment. J Clin Virol (2007) 1.08
Signaling through CD70 regulates B cell activation and IgG production. J Immunol (2004) 1.04
The human EGF-TM7 family member EMR2 is a heterodimeric receptor expressed on myeloid cells. J Leukoc Biol (2002) 1.04
B and T lymphocyte attenuator is highly expressed on CMV-specific T cells during infection and regulates their function. J Immunol (2010) 1.03
Human virus-specific effector-type T cells accumulate in blood but not in lymph nodes. Blood (2011) 1.02
CD40 stimulation of B-cell chronic lymphocytic leukaemia cells enhances the anti-apoptotic profile, but also Bid expression and cells remain susceptible to autologous cytotoxic T-lymphocyte attack. Br J Haematol (2004) 1.02
Cytomegalovirus-induced effector T cells cause endothelial cell damage. Clin Vaccine Immunol (2012) 1.02
Human cytomegalovirus infection induces a rapid and sustained change in the expression of NK cell receptors on CD8+ T cells. J Immunol (2008) 1.01
Cross-reactivity of cytomegalovirus-specific CD8+ T cells to allo-major histocompatibility complex class I molecules. Transplantation (2004) 1.01
IL-21 and CD40L signals from autologous T cells can induce antigen-independent proliferation of CLL cells. Blood (2013) 1.00
Expression of the largest CD97 and EMR2 isoforms on leukocytes facilitates a specific interaction with chondroitin sulfate on B cells. J Leukoc Biol (2004) 1.00
Development of virus-specific CD4+ T cells on reexposure to Varicella-Zoster virus. J Infect Dis (2004) 1.00
Notch controls the magnitude of T helper cell responses by promoting cellular longevity. Proc Natl Acad Sci U S A (2012) 0.99
Immune responsiveness in renal transplant recipients: mycophenolic acid severely depresses humoral immunity in vivo. Kidney Int (2002) 0.98
Cellular immune responses during high-dose interferon-alpha induction therapy for hepatitis C virus infection. J Infect Dis (2009) 0.97
Shear stress-dependent downregulation of the adhesion-G protein-coupled receptor CD97 on circulating leukocytes upon contact with its ligand CD55. J Immunol (2013) 0.97
Analysis of CD97 expression and manipulation: antibody treatment but not gene targeting curtails granulocyte migration. J Immunol (2008) 0.96
IL-7/anti-IL-7 mAb complexes augment cytokine potency in mice through association with IgG-Fc and by competition with IL-7R. Blood (2013) 0.94
Alloantigen-induced regulatory CD8+CD103+ T cells. Hum Immunol (2008) 0.94
BH3-only protein Noxa regulates apoptosis in activated B cells and controls high-affinity antibody formation. Blood (2011) 0.94
Apoptosis induced by overall metabolic stress converges on the Bcl-2 family proteins Noxa and Mcl-1. Apoptosis (2011) 0.93
Cutting edge: virus selectively primes human langerhans cells for CD70 expression promoting CD8+ T cell responses. J Immunol (2011) 0.93
Pro-apoptotic protein Noxa regulates memory T cell population size and protects against lethal immunopathology. J Immunol (2012) 0.92
CD27-CD70 costimulation controls T cell immunity during acute and persistent cytomegalovirus infection. J Virol (2013) 0.91
Induction and maintenance of CD8+ T cells specific for persistent viruses. Adv Exp Med Biol (2007) 0.91
A new subset of human naive CD8+ T cells defined by low expression of IL-7R alpha. J Immunol (2007) 0.90
Skewed maturation of virus-specific CTLs? Nat Immunol (2002) 0.89
Expression of the EGF-TM7 receptor CD97 and its ligand CD55 (DAF) in multiple sclerosis. J Neuroimmunol (2002) 0.89
Cutting edge: CD95 maintains effector T cell homeostasis in chronic immune activation. J Immunol (2005) 0.89
A reversion of an IL2RG mutation in combined immunodeficiency providing competitive advantage to the majority of CD8+ T cells. Haematologica (2013) 0.88
Withdrawal symptoms on display: Bcl-2 members under investigation. Trends Immunol (2006) 0.88
Characteristics of differentiated CD8(+) and CD4 (+) T cells present in the human brain. Acta Neuropathol (2013) 0.87
CD97 neutralisation increases resistance to collagen-induced arthritis in mice. Arthritis Res Ther (2006) 0.87
Apoptosis via the B cell antigen receptor requires Bax translocation and involves mitochondrial depolarization, cytochrome C release, and caspase-9 activation. Eur J Immunol (2004) 0.87
Phenotypic and functional characterization of circulating polyomavirus BK VP1-specific CD8+ T cells in healthy adults. J Virol (2013) 0.86
Monitoring the T-cell receptor repertoire at single-clone resolution. PLoS One (2006) 0.84
Analysis of stem-cell-like properties of human CD161++IL-18Rα+ memory CD8+ T cells. Int Immunol (2012) 0.83
Inactivation of the EGF-TM7 receptor EMR4 after the Pan-Homo divergence. Eur J Immunol (2003) 0.83
CXCR5+CD4+ follicular helper T cells accumulate in resting human lymph nodes and have superior B cell helper activity. Int Immunol (2013) 0.83
Expansion of effector T cells associated with decreased PD-1 expression in patients with indolent B cell lymphomas and chronic lymphocytic leukemia. Leuk Lymphoma (2012) 0.83
Identification of B cell defects using age-defined reference ranges for in vivo and in vitro B cell differentiation. J Immunol (2013) 0.82
Specific expression of GPR56 by human cytotoxic lymphocytes. J Leukoc Biol (2011) 0.82
Blood and beyond: properties of circulating and tissue-resident human virus-specific αβ CD8(+) T cells. Eur J Immunol (2014) 0.82
Circulating lymphocyte subsets in different clinical situations after renal transplantation. Immunology (2012) 0.82
Persistent detection of varicella-zoster virus DNA in a previously healthy child after severe chickenpox. J Clin Microbiol (2005) 0.82
Differentiation of human alloreactive CD4+ and CD8+ T cells in vitro. Transplantation (2004) 0.81
Spontaneous outgrowth of EBV-transformed B-cells reflects EBV-specific immunity in vivo; a useful tool in the follow-up of EBV-driven immunoproliferative disorders in allograft recipients. Transpl Int (2003) 0.80