Published in Biochemistry on April 18, 2008
The STRA6 receptor is essential for retinol-binding protein-induced insulin resistance but not for maintaining vitamin A homeostasis in tissues other than the eye. J Biol Chem (2013) 1.31
Retinoid content, visual responses, and ocular morphology are compromised in the retinas of mice lacking the retinol-binding protein receptor, STRA6. Invest Ophthalmol Vis Sci (2012) 1.27
Signaling by vitamin A and retinol-binding protein in regulation of insulin responses and lipid homeostasis. Biochim Biophys Acta (2011) 1.22
Liver retinol transporter and receptor for serum retinol-binding protein (RBP4). J Biol Chem (2012) 1.10
STRA6-catalyzed vitamin A influx, efflux, and exchange. J Membr Biol (2012) 1.05
First implication of STRA6 mutations in isolated anophthalmia, microphthalmia, and coloboma: a new dimension to the STRA6 phenotype. Hum Mutat (2011) 0.98
Tear lipocalin: structure and function. Ocul Surf (2011) 0.97
Identification of STRA6 and SKI sequence variants in patients with anophthalmia/microphthalmia. Mol Vis (2008) 0.95
The membrane receptor for plasma retinol-binding protein, a new type of cell-surface receptor. Int Rev Cell Mol Biol (2011) 0.94
Altered retinoid uptake and action contributes to cell survival in endometriosis. J Clin Endocrinol Metab (2010) 0.93
Apo-RBP, holo-RBP, and insulin resistance. Mol Cell Biol (2014) 0.92
Retina, retinol, retinal and the natural history of vitamin A as a light sensor. Nutrients (2012) 0.92
Vitamin A transport and the transmembrane pore in the cell-surface receptor for plasma retinol binding protein. PLoS One (2013) 0.87
Membrane receptors and transporters involved in the function and transport of vitamin A and its derivatives. Biochim Biophys Acta (2011) 0.84
Increased unbound retinol-binding protein 4 concentration induces apoptosis through receptor-mediated signaling. J Biol Chem (2012) 0.83
STRA6: role in cellular retinol uptake and efflux. Hepatobiliary Surg Nutr (2015) 0.80
How free retinol behaves differently from rbp-bound retinol in RBP receptor-mediated vitamin A uptake. Mol Cell Biol (2014) 0.80
Techniques to study specific cell-surface receptor-mediated cellular vitamin A uptake. Methods Mol Biol (2010) 0.79
Structure of the STRA6 receptor for retinol uptake. Science (2016) 0.78
Differential and isomer-specific modulation of vitamin A transport and the catalytic activities of the RBP receptor by retinoids. J Membr Biol (2013) 0.78
Adaptive evolution of the STRA6 genes in mammalian. PLoS One (2014) 0.78
An alternative retinoic acid-responsive Stra6 promoter regulated in response to retinol deficiency. J Biol Chem (2014) 0.78
Vitamin A Transport Mechanism of the Multitransmembrane Cell-Surface Receptor STRA6. Membranes (Basel) (2015) 0.77
Real-time analyses of retinol transport by the membrane receptor of plasma retinol binding protein. J Vis Exp (2013) 0.77
Molecular Basis for Vitamin A Uptake and Storage in Vertebrates. Nutrients (2016) 0.76
Signaling through retinoic acid receptors in cardiac development: Doing the right things at the right times. Biochim Biophys Acta (2014) 0.76
Production of functional human vitamin A transporter/RBP receptor (STRA6) for structure determination. PLoS One (2015) 0.75
Insights into the function of Rim protein in photoreceptors and etiology of Stargardt's disease from the phenotype in abcr knockout mice. Cell (1999) 5.76
The ABCs of solute carriers: physiological, pathological and therapeutic implications of human membrane transport proteinsIntroduction. Pflugers Arch (2003) 3.76
A membrane receptor for retinol binding protein mediates cellular uptake of vitamin A. Science (2007) 3.73
Function of retinoid nuclear receptors: lessons from genetic and pharmacological dissections of the retinoic acid signaling pathway during mouse embryogenesis. Annu Rev Pharmacol Toxicol (2006) 3.39
Mutations in STRA6 cause a broad spectrum of malformations including anophthalmia, congenital heart defects, diaphragmatic hernia, alveolar capillary dysplasia, lung hypoplasia, and mental retardation. Am J Hum Genet (2007) 2.74
Retinal stimulates ATP hydrolysis by purified and reconstituted ABCR, the photoreceptor-specific ATP-binding cassette transporter responsible for Stargardt disease. J Biol Chem (1999) 2.70
Developmental expression pattern of Stra6, a retinoic acid-responsive gene encoding a new type of membrane protein. Mech Dev (1997) 1.89
Matthew-Wood syndrome is caused by truncating mutations in the retinol-binding protein receptor gene STRA6. Am J Hum Genet (2007) 1.86
Biochemical defects in ABCR protein variants associated with human retinopathies. Nat Genet (2000) 1.73
In vitro uptake of vitamin A from the retinol-binding plasma protein to mucosal epithelial cells from the monkey's small intestine. J Biol Chem (1976) 1.62
Interactions of plasma retinol-binding protein with its receptor. Specific binding of bovine and human retinol-binding protein to pigment epithelium cells from bovine eyes. J Biol Chem (1975) 1.42
Overexpression of the retinoic acid-responsive gene Stra6 in human cancers and its synergistic induction by Wnt-1 and retinoic acid. Cancer Res (2001) 1.40
Plasma retinol binding protein: structure and function of the prototypic lipocalin. Biochim Biophys Acta (2000) 1.37
The interaction of retinol-binding protein with its plasma-membrane receptor. Biochem J (1988) 1.29
The effect of lipid environment and retinoids on the ATPase activity of ABCR, the photoreceptor ABC transporter responsible for Stargardt macular dystrophy. J Biol Chem (2000) 1.28
Localization of cellular retinol-binding protein and retinol-binding protein in cells comprising the blood-brain barrier of rat and human. Proc Natl Acad Sci U S A (1990) 1.23
Transport of retinol from the blood to the retina: an autoradiographic study of the pigment epithelial cell surface receptor for plasma retinol-binding protein. Exp Eye Res (1976) 1.18
Plasma retinol-binding protein: structure and interactions with retinol, retinoids, and transthyretin. Vitam Horm (2004) 1.17
Site-directed alkylation of cysteine to test solvent accessibility of membrane proteins. Nat Protoc (2007) 1.15
Promotion of the release of 11-cis-retinal from cultured retinal pigment epithelium by interphotoreceptor retinoid-binding protein. Biochemistry (1992) 1.15
Uptake of retinol and retinoic acid from serum retinol-binding protein by retinal pigment epithelial cells. J Biol Chem (1977) 1.11
Characteristics of retinol accumulation from serum retinol-binding protein by cultured Sertoli cells. Biochemistry (1989) 1.10
Transmembrane organization of the Na,K-ATPase determined by epitope addition. Biochemistry (1993) 1.08
Insertional mutagenesis as a probe of rhodopsin's topography, stability, and activity. J Biol Chem (1994) 1.06
The function of vitamin A in cellular growth and differentiation, and its roles during pregnancy and lactation. Adv Exp Med Biol (1994) 1.00
Structure-function studies on human retinol-binding protein using site-directed mutagenesis. Biochem J (1994) 1.00
Tissue distribution of the receptor for plasma retinol-binding protein. Biochem J (1995) 0.96
Vitamin A uptake by human skin in vitro. Arch Dermatol Res (1984) 0.92
Specificity of the retinol transporter of the rat small intestine brush border. Biochemistry (1994) 0.92
Gonadal cell surface receptor for plasma retinol-binding protein. A method for its radioassay and studies on its level during spermatogenesis. Biochim Biophys Acta (1979) 0.90
Transport of retinol from the blood to the retina: involvement of high molecular weight lipoproteins as intracellular carriers. Exp Eye Res (1976) 0.83
Binding of retinol to isolated retinal pigment epithelium in the presence and absence of retinol-binding protein. Invest Ophthalmol (1975) 0.82
Polarity of 11-cis retinal release from cultured retinal pigment epithelium. Invest Ophthalmol Vis Sci (1999) 0.82
Development of a versatile reporter assay for studies of retinol uptake and metabolism in vivo. Exp Cell Res (2005) 0.81
Comparison of genome degradation in Paratyphi A and Typhi, human-restricted serovars of Salmonella enterica that cause typhoid. Nat Genet (2004) 8.60
A variant of the HTRA1 gene increases susceptibility to age-related macular degeneration. Science (2006) 5.67
The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes. Science (2012) 4.93
Genome-wide analysis of PTB-RNA interactions reveals a strategy used by the general splicing repressor to modulate exon inclusion or skipping. Mol Cell (2009) 4.71
Rpe65 is the retinoid isomerase in bovine retinal pigment epithelium. Cell (2005) 4.51
Regulation of myocardial contractility and cell size by distinct PI3K-PTEN signaling pathways. Cell (2002) 4.35
A membrane receptor for retinol binding protein mediates cellular uptake of vitamin A. Science (2007) 3.73
The DNA sequence of human chromosome 7. Nature (2003) 3.18
Metamaterials application in sensing. Sensors (Basel) (2012) 3.09
The role of phosphoinositide-3 kinase and PTEN in cardiovascular physiology and disease. J Mol Cell Cardiol (2004) 2.90
Highly prevalent TERT promoter mutations in aggressive thyroid cancers. Endocr Relat Cancer (2013) 2.69
Glutamate receptors: RNA editing and death of motor neurons. Nature (2004) 2.53
Direct conversion of fibroblasts to neurons by reprogramming PTB-regulated microRNA circuits. Cell (2013) 2.43
Genome-wide and organ-specific landscapes of epigenetic modifications and their relationships to mRNA and small RNA transcriptomes in maize. Plant Cell (2009) 2.39
L-type Ca2+ channels provide a major pathway for iron entry into cardiomyocytes in iron-overload cardiomyopathy. Nat Med (2003) 2.38
The Arabidopsis heterochronic gene ZIPPY is an ARGONAUTE family member. Curr Biol (2003) 2.31
Structure-function analysis of the bestrophin family of anion channels. J Biol Chem (2003) 2.30
Generation and annotation of the DNA sequences of human chromosomes 2 and 4. Nature (2005) 2.27
Gaussian Bare-Bones Differential Evolution. IEEE Trans Cybern (2013) 2.08
Activation of STAT6 by STING is critical for antiviral innate immunity. Cell (2011) 2.08
Streptococcus suis sequence type 7 outbreak, Sichuan, China. Emerg Infect Dis (2006) 2.07
PCBP2 mediates degradation of the adaptor MAVS via the HECT ubiquitin ligase AIP4. Nat Immunol (2009) 2.07
The DNA sequence and analysis of human chromosome 14. Nature (2003) 2.02
The genomes of the fungal plant pathogens Cladosporium fulvum and Dothistroma septosporum reveal adaptation to different hosts and lifestyles but also signatures of common ancestry. PLoS Genet (2012) 1.95
Sequence and comparative analysis of the maize NB mitochondrial genome. Plant Physiol (2004) 1.83
Genome analysis of the anaerobic thermohalophilic bacterium Halothermothrix orenii. PLoS One (2009) 1.83
Three-column fixation for complex tibial plateau fractures. J Orthop Trauma (2010) 1.73
A pilot study of high-throughput, sequence-based mutational profiling of primary human acute myeloid leukemia cell genomes. Proc Natl Acad Sci U S A (2003) 1.69
Sphingolipid-modulated exosome secretion promotes clearance of amyloid-β by microglia. J Biol Chem (2012) 1.66
Effects of methylphenidate on acute math performance in children with attention-deficit hyperactivity disorder. Can J Psychiatry (2013) 1.61
A genomic analysis of the archaeal system Ignicoccus hospitalis-Nanoarchaeum equitans. Genome Biol (2008) 1.60
Retracted Predicting new molecular targets for rhein using network pharmacology. BMC Syst Biol (2012) 1.55
Comparisons among two fertile and three male-sterile mitochondrial genomes of maize. Genetics (2007) 1.53
TERT promoter mutations and their association with BRAF V600E mutation and aggressive clinicopathological characteristics of thyroid cancer. J Clin Endocrinol Metab (2014) 1.52
Modern analytical techniques in metabolomics analysis. Analyst (2011) 1.52
The effect of dipeptidyl peptidase-IV inhibition on bone in a mouse model of type 2 diabetes. Diabetes Metab Res Rev (2014) 1.45
Increased tumor growth in mice with diet-induced obesity: impact of ovarian hormones. Endocrinology (2006) 1.44
Comparative genomics of xylose-fermenting fungi for enhanced biofuel production. Proc Natl Acad Sci U S A (2011) 1.39
Resveratrol improves non-alcoholic fatty liver disease by activating AMP-activated protein kinase. Acta Pharmacol Sin (2008) 1.38
Power of metabolomics in diagnosis and biomarker discovery of hepatocellular carcinoma. Hepatology (2013) 1.38
The ternary IGF complex influences postnatal bone acquisition and the skeletal response to intermittent parathyroid hormone. J Endocrinol (2006) 1.37
Urine metabolomics analysis for biomarker discovery and detection of jaundice syndrome in patients with liver disease. Mol Cell Proteomics (2012) 1.36
Metabolomics coupled with proteomics advancing drug discovery toward more agile development of targeted combination therapies. Mol Cell Proteomics (2013) 1.34
Potential role of metabolomics apporoaches in the area of traditional Chinese medicine: as pillars of the bridge between Chinese and Western medicine. J Pharm Biomed Anal (2011) 1.33
Phylogenetic and phylogenomic overview of the Polyporales. Mycologia (2013) 1.33
Future perspectives of Chinese medical formulae: chinmedomics as an effector. OMICS (2012) 1.32
Serum IGF-1 determines skeletal strength by regulating subperiosteal expansion and trait interactions. J Bone Miner Res (2009) 1.29
Metabolomics: towards understanding traditional Chinese medicine. Planta Med (2010) 1.24
Serum complexes of insulin-like growth factor-1 modulate skeletal integrity and carbohydrate metabolism. FASEB J (2008) 1.23
Serum metabolomics as a novel diagnostic approach for disease: a systematic review. Anal Bioanal Chem (2012) 1.22
Recent advances in natural products from plants for treatment of liver diseases. Eur J Med Chem (2013) 1.22
Elevated levels of insulin-like growth factor (IGF)-I in serum rescue the severe growth retardation of IGF-I null mice. Endocrinology (2009) 1.21
Receptor-mediated cellular uptake mechanism that couples to intracellular storage. ACS Chem Biol (2011) 1.20
Mechanisms of action of the congenital diaphragmatic hernia-inducing teratogen nitrofen. Am J Physiol Lung Cell Mol Physiol (2007) 1.19
Potential drug targets on insomnia and intervention effects of Jujuboside A through metabolic pathway analysis as revealed by UPLC/ESI-SYNAPT-HDMS coupled with pattern recognition approach. J Proteomics (2011) 1.19
Targeted loss of GHR signaling in mouse skeletal muscle protects against high-fat diet-induced metabolic deterioration. Diabetes (2012) 1.18
Functional CRH variation increases stress-induced alcohol consumption in primates. Proc Natl Acad Sci U S A (2009) 1.18
Transgenic mice expressing variants of complement factor H develop AMD-like retinal findings. Invest Ophthalmol Vis Sci (2010) 1.17
An in vivo analysis of the therapeutic and synergistic properties of Chinese medicinal formula Yin-Chen-Hao-Tang based on its active constituents. Fitoterapia (2011) 1.17
Complement factor H genotypes impact risk of age-related macular degeneration by interaction with oxidized phospholipids. Proc Natl Acad Sci U S A (2012) 1.16
miR-1 exacerbates cardiac ischemia-reperfusion injury in mouse models. PLoS One (2012) 1.15
Suppression of alcohol preference by naltrexone in the rhesus macaque: a critical role of genetic variation at the micro-opioid receptor gene locus. Biol Psychiatry (2010) 1.14
Nuclear matrix factor hnRNP U/SAF-A exerts a global control of alternative splicing by regulating U2 snRNP maturation. Mol Cell (2012) 1.14
Lifespan extension and elevated hsp gene expression in Drosophila caused by histone deacetylase inhibitors. J Exp Biol (2005) 1.14
An essential ligand-binding domain in the membrane receptor for retinol-binding protein revealed by large-scale mutagenesis and a human polymorphism. J Biol Chem (2008) 1.12
Growth hormone receptor regulates β cell hyperplasia and glucose-stimulated insulin secretion in obese mice. J Clin Invest (2011) 1.12
Elevated serum levels of IGF-1 are sufficient to establish normal body size and skeletal properties even in the absence of tissue IGF-1. J Bone Miner Res (2010) 1.12
Recent and potential developments of biofluid analyses in metabolomics. J Proteomics (2011) 1.11
Saliva metabolomics opens door to biomarker discovery, disease diagnosis, and treatment. Appl Biochem Biotechnol (2012) 1.11
Functional analysis of a novel Cys2/His2-type zinc finger protein involved in salt tolerance in rice. J Exp Bot (2010) 1.11
microRNA-206 in rat medial prefrontal cortex regulates BDNF expression and alcohol drinking. J Neurosci (2014) 1.11
PAUSED encodes the Arabidopsis exportin-t ortholog. Plant Physiol (2003) 1.10
A Wnt-Frz/Ror-Dsh pathway regulates neurite outgrowth in Caenorhabditis elegans. PLoS Genet (2010) 1.09
Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens. PLoS Genet (2013) 1.09
Cardiac-specific elevations in thyroid hormone enhance contractility and prevent pressure overload-induced cardiac dysfunction. Proc Natl Acad Sci U S A (2006) 1.08
Long-term combination antiretroviral therapy is associated with the risk of coronary plaques in African Americans with HIV infection. AIDS Patient Care STDS (2009) 1.08
Delta9-tetrahydrocannabinol and endogenous cannabinoid anandamide directly potentiate the function of glycine receptors. Mol Pharmacol (2005) 1.07
The complete genome sequence of Staphylothermus marinus reveals differences in sulfur metabolism among heterotrophic Crenarchaeota. BMC Genomics (2009) 1.07
Insulin-like growth factor-I regulates the liver microenvironment in obese mice and promotes liver metastasis. Cancer Res (2010) 1.07
Metabolomics study on the hepatoprotective effect of scoparone using ultra-performance liquid chromatography/electrospray ionization quadruple time-of-flight mass spectrometry. Analyst (2012) 1.07
An antitumour lectin from the edible mushroom Agrocybe aegerita. Biochem J (2003) 1.07
Human NPY promoter variation rs16147:T>C as a moderator of prefrontal NPY gene expression and negative affect. Hum Mutat (2010) 1.06
STRA6-catalyzed vitamin A influx, efflux, and exchange. J Membr Biol (2012) 1.05
Functional NPY variation as a factor in stress resilience and alcohol consumption in rhesus macaques. Arch Gen Psychiatry (2010) 1.05
Biomechanical analysis of four different fixations for the posterolateral shearing tibial plateau fracture. Knee (2011) 1.05
Loss of membrane cholesterol influences lysosomal permeability to potassium ions and protons. Biochim Biophys Acta (2008) 1.05
Serum IGF-1 affects skeletal acquisition in a temporal and compartment-specific manner. PLoS One (2011) 1.04
Exploratory urinary metabolic biomarkers and pathways using UPLC-Q-TOF-HDMS coupled with pattern recognition approach. Analyst (2012) 1.04
Biochemical analysis of a common human polymorphism associated with age-related macular degeneration. Biochemistry (2007) 1.03