Characterization of gene expression regulated by American ginseng and ginsenoside Rg3 in human colorectal cancer cells.

PubWeight™: 1.15‹?› | Rank: Top 10%

🔗 View Article (PMC 2677725)

Published in Int J Oncol on May 01, 2008

Authors

Xiaoji Luo1, Chong-Zhi Wang, Jin Chen, Wen-Xin Song, Jinyong Luo, Ni Tang, Bai-Cheng He, Quan Kang, Yitao Wang, Wei Du, Tong-Chuan He, Chun-Su Yuan

Author Affiliations

1: Molecular Oncology Laboratory, Department of Surgery, The University of Chicago, Chicago, IL 60637, USA.

Articles citing this

Anti-cancer natural products isolated from chinese medicinal herbs. Chin Med (2011) 1.39

Ginsenosides as Anticancer Agents: In vitro and in vivo Activities, Structure-Activity Relationships, and Molecular Mechanisms of Action. Front Pharmacol (2012) 1.35

Ginsenoside Rh2 induces apoptosis and paraptosis-like cell death in colorectal cancer cells through activation of p53. Cancer Lett (2010) 1.33

Antioxidants potentiate American ginseng-induced killing of colorectal cancer cells. Cancer Lett (2009) 1.21

Effects of ginsenoside Rh2 on growth and migration of pancreatic cancer cells. World J Gastroenterol (2013) 1.02

American ginseng suppresses Western diet-promoted tumorigenesis in model of inflammation-associated colon cancer: role of EGFR. BMC Complement Altern Med (2011) 0.98

Mechanistic insight into the ability of American ginseng to suppress colon cancer associated with colitis. Carcinogenesis (2010) 0.92

Ginseng saponin metabolite 20(S)-protopanaxadiol inhibits tumor growth by targeting multiple cancer signaling pathways. Oncol Rep (2013) 0.91

Ginsenoside Rg3 inhibit hepatocellular carcinoma growth via intrinsic apoptotic pathway. World J Gastroenterol (2011) 0.90

Systems biology of meridians, acupoints, and chinese herbs in disease. Evid Based Complement Alternat Med (2012) 0.85

Pharmacological effects of ginseng on liver functions and diseases: a minireview. Evid Based Complement Alternat Med (2012) 0.84

Caspase-mediated pro-apoptotic interaction of panaxadiol and irinotecan in human colorectal cancer cells. J Pharm Pharmacol (2012) 0.82

American ginseng attenuates azoxymethane/dextran sodium sulfate-induced colon carcinogenesis in mice. J Ginseng Res (2014) 0.82

Drosophila Ric-8 interacts with the Gα12/13 subunit, Concertina, during activation of the Folded gastrulation pathway. Mol Biol Cell (2013) 0.80

Effect of sun ginseng potentiation on epirubicin and paclitaxel-induced apoptosis in human cervical cancer cells. J Ginseng Res (2014) 0.79

Effects of Oplopanax horridus on human colorectal cancer cells. Anticancer Res (2010) 0.78

American ginseng regulates gene expression to protect against premature ovarian failure in rats. Biomed Res Int (2015) 0.78

Ginsenoside Rg3 enhances the inhibitory effects of chemotherapy on esophageal squamous cell carcinoma in mice. Mol Clin Oncol (2014) 0.77

Chemopreventive effects of oplopantriol A, a novel compound isolated from Oplopanax horridus, on colorectal cancer. Nutrients (2014) 0.76

Antioxidant-rich leaf extract of Barringtonia racemosa significantly alters the in vitro expression of genes encoding enzymes that are involved in methylglyoxal degradation III. PeerJ (2016) 0.75

DNA Microarray-Based Screening and  Characterization of Traditional Chinese Medicine. Microarrays (Basel) (2017) 0.75

Effect of Korean Red Ginseng in chronic liver disease. J Ginseng Res (2017) 0.75

Articles cited by this

Model-based analysis of oligonucleotide arrays: expression index computation and outlier detection. Proc Natl Acad Sci U S A (2001) 68.44

Cancer statistics, 2004. CA Cancer J Clin (2004) 15.72

A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway. Nat Cell Biol (2004) 7.23

The role of ephrins and Eph receptors in cancer. Cytokine Growth Factor Rev (2004) 2.23

Cancer prevention and therapeutics: Panax ginseng. Altern Med Rev (2004) 2.22

Red American ginseng: ginsenoside constituents and antiproliferative activities of heat-processed Panax quinquefolius roots. Planta Med (2007) 1.96

The biological functions of A-kinase anchor proteins. J Mol Biol (2001) 1.88

Inhibitor of DNA binding/differentiation helix-loop-helix proteins mediate bone morphogenetic protein-induced osteoblast differentiation of mesenchymal stem cells. J Biol Chem (2004) 1.71

Steamed American ginseng berry: ginsenoside analyses and anticancer activities. J Agric Food Chem (2006) 1.68

Anticarcinogenic effect of Panax ginseng C.A. Meyer and identification of active compounds. J Korean Med Sci (2001) 1.62

The A-kinase-anchoring protein AKAP95 is a multivalent protein with a key role in chromatin condensation at mitosis. J Cell Biol (1999) 1.57

Commonly used antioxidant botanicals: active constituents and their potential role in cardiovascular illness. Am J Chin Med (2007) 1.53

Effects of ginsenosides Rg3 and Rh2 on the proliferation of prostate cancer cells. Arch Pharm Res (2004) 1.51

The diverse biological functions of phosphatidylinositol transfer proteins in eukaryotes. Crit Rev Biochem Mol Biol (2006) 1.40

A kinase-anchoring protein (AKAP)95 recruits human chromosome-associated protein (hCAP)-D2/Eg7 for chromosome condensation in mitotic extract. J Cell Biol (2000) 1.33

Saponins composition in American ginseng leaf and berry assayed by high-performance liquid chromatography. J Agric Food Chem (2006) 1.31

Cloning and characterization of AKAP 95, a nuclear protein that associates with the regulatory subunit of type II cAMP-dependent protein kinase. J Biol Chem (1994) 1.29

Phospholipid transfer proteins in perspective. FEBS Lett (2006) 1.14

American ginseng berry extract and ginsenoside Re attenuate cisplatin-induced kaolin intake in rats. Cancer Chemother Pharmacol (2005) 1.07

Chemopreventive effects of Panax notoginseng and its major constituents on SW480 human colorectal cancer cells. Int J Oncol (2007) 1.04

HA95 is a protein of the chromatin and nuclear matrix regulating nuclear envelope dynamics. J Cell Sci (2000) 1.04

Effects of ginseng on the proliferation of human lung fibroblasts. Am J Chin Med (2006) 1.03

HA95 and LAP2 beta mediate a novel chromatin-nuclear envelope interaction implicated in initiation of DNA replication. J Cell Biol (2003) 1.03

A-kinase anchoring proteins and neuronal signaling mechanisms. Genes Dev (2003) 1.01

Cisplatin's tumoricidal effect on human breast carcinoma MCF-7 cells was not attenuated by American ginseng. Cancer Chemother Pharmacol (2006) 0.99

Mountain grown ginseng induces apoptosis in HL-60 cells and its mechanism have little relation with TNF-alpha production. Am J Chin Med (2007) 0.96

The influence of lead and arsenite on the inhibition of human breast cancer MCF-7 cell proliferation by American ginseng root (Panax quinquefolius L.). Life Sci (2005) 0.90

Identification, cloning and characterization of a novel nuclear protein, HA95, homologous to A-kinase anchoring protein 95. Biol Cell (2000) 0.90

In vitro modulation of the interaction between HA95 and LAP2beta by cAMP signaling. Biochemistry (2003) 0.82

Articles by these authors

TERT promoter mutations occur frequently in gliomas and a subset of tumors derived from cells with low rates of self-renewal. Proc Natl Acad Sci U S A (2013) 6.88

A protocol for rapid generation of recombinant adenoviruses using the AdEasy system. Nat Protoc (2007) 5.15

Regional anesthesia in the patient receiving antithrombotic or thrombolytic therapy: American Society of Regional Anesthesia and Pain Medicine Evidence-Based Guidelines (Third Edition). Reg Anesth Pain Med (2010) 4.77

Blockade of TGF-beta inhibits mammary tumor cell viability, migration, and metastases. J Clin Invest (2002) 4.64

Regional anesthesia in the anticoagulated patient: defining the risks (the second ASRA Consensus Conference on Neuraxial Anesthesia and Anticoagulation). Reg Anesth Pain Med (2003) 3.85

Osteogenic activity of the fourteen types of human bone morphogenetic proteins (BMPs). J Bone Joint Surg Am (2003) 3.36

Pathogenomic sequence analysis of Bacillus cereus and Bacillus thuringiensis isolates closely related to Bacillus anthracis. J Bacteriol (2006) 3.23

Homer binds TRPC family channels and is required for gating of TRPC1 by IP3 receptors. Cell (2003) 3.11

Common variants associated with plasma triglycerides and risk for coronary artery disease. Nat Genet (2013) 2.92

Mutant huntingtin binds the mitochondrial fission GTPase dynamin-related protein-1 and increases its enzymatic activity. Nat Med (2011) 2.87

Induction therapy with autologous mesenchymal stem cells in living-related kidney transplants: a randomized controlled trial. JAMA (2012) 2.85

The first identification of lysine malonylation substrates and its regulatory enzyme. Mol Cell Proteomics (2011) 2.83

Treatment with CD20-specific antibody prevents and reverses autoimmune diabetes in mice. J Clin Invest (2007) 2.81

Podocyte-selective deletion of dicer induces proteinuria and glomerulosclerosis. J Am Soc Nephrol (2008) 2.74

Antidiabetic effects of Panax ginseng berry extract and the identification of an effective component. Diabetes (2002) 2.64

Factors associated with breast cancer clinical trials participation and enrollment at a large academic medical center. J Clin Oncol (2004) 2.55

Pancreatic islet production of vascular endothelial growth factor--a is essential for islet vascularization, revascularization, and function. Diabetes (2006) 2.53

Soluble Eph A receptors inhibit tumor angiogenesis and progression in vivo. Oncogene (2002) 2.41

Hedgehog regulates cell growth and proliferation by inducing Cyclin D and Cyclin E. Nature (2002) 2.40

Regression equations for calculation of z scores of cardiac structures in a large cohort of healthy infants, children, and adolescents: an echocardiographic study. J Am Soc Echocardiogr (2008) 2.38

Connective tissue growth factor (CTGF) is regulated by Wnt and bone morphogenetic proteins signaling in osteoblast differentiation of mesenchymal stem cells. J Biol Chem (2004) 2.35

Distinct roles of bone morphogenetic proteins in osteogenic differentiation of mesenchymal stem cells. J Orthop Res (2007) 2.26

Perspectives of microbial oils for biodiesel production. Appl Microbiol Biotechnol (2008) 2.25

Osteosarcoma development and stem cell differentiation. Clin Orthop Relat Res (2008) 2.18

CCN1/Cyr61 is regulated by the canonical Wnt signal and plays an important role in Wnt3A-induced osteoblast differentiation of mesenchymal stem cells. Mol Cell Biol (2006) 2.15

The receptor tyrosine kinase EphA2 promotes mammary adenocarcinoma tumorigenesis and metastatic progression in mice by amplifying ErbB2 signaling. J Clin Invest (2008) 2.11

Isolation and analysis of ginseng: advances and challenges. Nat Prod Rep (2011) 2.10

Blockade of EphA receptor tyrosine kinase activation inhibits vascular endothelial cell growth factor-induced angiogenesis. Mol Cancer Res (2002) 1.96

Red American ginseng: ginsenoside constituents and antiproliferative activities of heat-processed Panax quinquefolius roots. Planta Med (2007) 1.96

Molecular classification of cancer types from microarray data using the combination of genetic algorithms and support vector machines. FEBS Lett (2003) 1.90

Acetylation modulates cellular distribution and DNA sensing ability of interferon-inducible protein IFI16. Proc Natl Acad Sci U S A (2012) 1.88

Regulation of osteogenic differentiation during skeletal development. Front Biosci (2008) 1.88

A comprehensive analysis of the dual roles of BMPs in regulating adipogenic and osteogenic differentiation of mesenchymal progenitor cells. Stem Cells Dev (2009) 1.87

Seed size, more than nutrient or tannin content, affects seed caching behavior of a common genus of Old World rodents. Ecology (2009) 1.85

Ginseng and diabetes. Am J Chin Med (2005) 1.83

An orthotopic model of human osteosarcoma growth and spontaneous pulmonary metastasis. Clin Exp Metastasis (2005) 1.82

EphA2 receptor tyrosine kinase regulates endothelial cell migration and vascular assembly through phosphoinositide 3-kinase-mediated Rac1 GTPase activation. J Cell Sci (2004) 1.82

Chemical and pharmacological studies of saponins with a focus on American ginseng. J Ginseng Res (2010) 1.81

The ephrins and Eph receptors in angiogenesis. Cytokine Growth Factor Rev (2002) 1.80

Aging promotes neutrophil-induced mortality by augmenting IL-17 production during viral infection. Cell Host Microbe (2009) 1.78

Comprehensive proteomic profiling of the membrane constituents of a Mycobacterium tuberculosis strain. Mol Cell Proteomics (2003) 1.77

Transferable anticancer innate immunity in spontaneous regression/complete resistance mice. Proc Natl Acad Sci U S A (2006) 1.77

Recent advances in tumor-targeting anticancer drug conjugates. Bioorg Med Chem (2005) 1.77

Cholesterol-regulated translocation of NPC1L1 to the cell surface facilitates free cholesterol uptake. J Biol Chem (2005) 1.75

TRP-ML1 is a lysosomal monovalent cation channel that undergoes proteolytic cleavage. J Biol Chem (2005) 1.75

Mycobacterium tuberculosis functional network analysis by global subcellular protein profiling. Mol Biol Cell (2004) 1.73

The ephrin receptor tyrosine kinase A2 is a cellular receptor for Kaposi's sarcoma–associated herpesvirus. Nat Med (2012) 1.72

Wnt/beta-catenin signaling pathway as a novel cancer drug target. Curr Cancer Drug Targets (2004) 1.72

Inhibitor of DNA binding/differentiation helix-loop-helix proteins mediate bone morphogenetic protein-induced osteoblast differentiation of mesenchymal stem cells. J Biol Chem (2004) 1.71

BMP-14 gene therapy increases tendon tensile strength in a rat model of Achilles tendon injury. J Bone Joint Surg Am (2007) 1.70

Effects of American ginseng berry extract on blood glucose levels in ob/ob mice. Am J Chin Med (2002) 1.69

Steamed American ginseng berry: ginsenoside analyses and anticancer activities. J Agric Food Chem (2006) 1.68

American ginseng: potential structure-function relationship in cancer chemoprevention. Biochem Pharmacol (2010) 1.65

Potential role of ginseng in the treatment of colorectal cancer. Am J Chin Med (2008) 1.65

Molecular and cellular approaches for the detection of protein-protein interactions: latest techniques and current limitations. Plant J (2008) 1.62

Monte Carlo based method for fluorescence tomographic imaging with lifetime multiplexing using time gates. Biomed Opt Express (2011) 1.61

Impaired tumor microenvironment in EphA2-deficient mice inhibits tumor angiogenesis and metastatic progression. FASEB J (2005) 1.61

Ginsenosides from American ginseng: chemical and pharmacological diversity. Phytochemistry (2011) 1.61

A kinase-dependent role for EphA2 receptor in promoting tumor growth and metastasis. Oncogene (2005) 1.59

Sleep-deprived young drivers and the risk for crash: the DRIVE prospective cohort study. JAMA Pediatr (2013) 1.59

Insulin-like growth factor 2 (IGF-2) potentiates BMP-9-induced osteogenic differentiation and bone formation. J Bone Miner Res (2010) 1.58

Plant DNA barcoding: from gene to genome. Biol Rev Camb Philos Soc (2014) 1.56

Alvimopan, a novel, peripherally acting mu opioid antagonist: results of a multicenter, randomized, double-blind, placebo-controlled, phase III trial of major abdominal surgery and postoperative ileus. Ann Surg (2004) 1.56

Eph receptor tyrosine kinases in angiogenesis: from development to disease. Angiogenesis (2004) 1.55

EphA2 receptor tyrosine kinase as a promising target for cancer therapeutics. Curr Cancer Drug Targets (2005) 1.54

BMP-9-induced osteogenic differentiation of mesenchymal progenitors requires functional canonical Wnt/beta-catenin signalling. J Cell Mol Med (2008) 1.54