Published in Science on April 25, 2008
Lipid-like materials for low-dose, in vivo gene silencing. Proc Natl Acad Sci U S A (2010) 4.25
Virus entry by macropinocytosis. Nat Cell Biol (2009) 3.87
Shaping cups into phagosomes and macropinosomes. Nat Rev Mol Cell Biol (2008) 3.62
Cell motility through plasma membrane blebbing. J Cell Biol (2008) 3.29
Role of cortical tension in bleb growth. Proc Natl Acad Sci U S A (2009) 3.08
Targeted and armed oncolytic poxviruses: a novel multi-mechanistic therapeutic class for cancer. Nat Rev Cancer (2009) 3.06
Ebolavirus is internalized into host cells via macropinocytosis in a viral glycoprotein-dependent manner. PLoS Pathog (2010) 2.60
Cellular entry of ebola virus involves uptake by a macropinocytosis-like mechanism and subsequent trafficking through early and late endosomes. PLoS Pathog (2010) 2.60
Vesicular stomatitis virus enters cells through vesicles incompletely coated with clathrin that depend upon actin for internalization. PLoS Pathog (2009) 2.59
Phagosome maturation: going through the acid test. Nat Rev Mol Cell Biol (2008) 2.53
Simultaneous cell-to-cell transmission of human immunodeficiency virus to multiple targets through polysynapses. J Virol (2009) 2.33
The soluble serum protein Gas6 bridges virion envelope phosphatidylserine to the TAM receptor tyrosine kinase Axl to mediate viral entry. Cell Host Microbe (2011) 2.25
Innate immune sensing of modified vaccinia virus Ankara (MVA) is mediated by TLR2-TLR6, MDA-5 and the NALP3 inflammasome. PLoS Pathog (2009) 2.24
Subcellular targeting strategies for drug design and delivery. Nat Rev Drug Discov (2010) 2.04
The TIM and TAM families of phosphatidylserine receptors mediate dengue virus entry. Cell Host Microbe (2012) 2.03
Cytonemes and tunneling nanotubules in cell-cell communication and viral pathogenesis. Trends Cell Biol (2008) 1.99
The evolutionary conundrum of pathogen mimicry. Nat Rev Microbiol (2009) 1.87
Isoform and splice-variant specific functions of dynamin-2 revealed by analysis of conditional knock-out cells. Mol Biol Cell (2008) 1.84
Virus cell-to-cell transmission. J Virol (2010) 1.84
Host cell factors and functions involved in vesicular stomatitis virus entry. J Virol (2008) 1.83
Subversion of the actin cytoskeleton during viral infection. Nat Rev Microbiol (2011) 1.77
Entry of human papillomavirus type 16 by actin-dependent, clathrin- and lipid raft-independent endocytosis. PLoS Pathog (2012) 1.76
The cell biology of receptor-mediated virus entry. J Cell Biol (2011) 1.75
Molecular mechanisms of clathrin-independent endocytosis. J Cell Sci (2009) 1.72
A new paradigm for aptamer therapeutic AS1411 action: uptake by macropinocytosis and its stimulation by a nucleolin-dependent mechanism. Cancer Res (2010) 1.72
Listeria monocytogenes exploits efferocytosis to promote cell-to-cell spread. Nature (2014) 1.70
Human papillomavirus type 16 entry: retrograde cell surface transport along actin-rich protrusions. PLoS Pathog (2008) 1.69
Actin Dynamics Regulates Dendritic Cell-Mediated Transfer of HIV-1 to T Cells. Cell (2016) 1.66
Dissection of the influenza A virus endocytic routes reveals macropinocytosis as an alternative entry pathway. PLoS Pathog (2011) 1.66
Targeting inside-out phosphatidylserine as a therapeutic strategy for viral diseases. Nat Med (2008) 1.64
Direct identification of ligand-receptor interactions on living cells and tissues. Nat Biotechnol (2012) 1.64
Increased expression of LDL receptor-related protein 1 during human cytomegalovirus infection reduces virion cholesterol and infectivity. Cell Host Microbe (2012) 1.59
Biology of the TAM receptors. Cold Spring Harb Perspect Biol (2013) 1.59
Squalamine as a broad-spectrum systemic antiviral agent with therapeutic potential. Proc Natl Acad Sci U S A (2011) 1.57
TIM-family proteins promote infection of multiple enveloped viruses through virion-associated phosphatidylserine. PLoS Pathog (2013) 1.53
Phosphatidylinositol 3-kinase-, actin-, and microtubule-dependent transport of Semliki Forest Virus replication complexes from the plasma membrane to modified lysosomes. J Virol (2010) 1.52
PAK1 as a therapeutic target. Expert Opin Ther Targets (2010) 1.48
Vaccinia virus strains use distinct forms of macropinocytosis for host-cell entry. Proc Natl Acad Sci U S A (2010) 1.45
Phosphatidylserine targeting for diagnosis and treatment of human diseases. Apoptosis (2010) 1.42
Enveloped viruses disable innate immune responses in dendritic cells by direct activation of TAM receptors. Cell Host Microbe (2013) 1.42
Arp2/3-mediated actin-based motility: a tail of pathogen abuse. Cell Host Microbe (2013) 1.40
A kinome RNAi screen identified AMPK as promoting poxvirus entry through the control of actin dynamics. PLoS Pathog (2010) 1.39
Nucleic acid delivery: the missing pieces of the puzzle? Acc Chem Res (2012) 1.36
Linking phospholipid flippases to vesicle-mediated protein transport. Biochim Biophys Acta (2009) 1.34
Optical imaging of mammary and prostate tumors in living animals using a synthetic near infrared zinc(II)-dipicolylamine probe for anionic cell surfaces. J Am Chem Soc (2010) 1.34
Activation of the PI3K/Akt pathway early during vaccinia and cowpox virus infections is required for both host survival and viral replication. J Virol (2009) 1.30
Role of the phosphatidylserine receptor TIM-1 in enveloped-virus entry. J Virol (2013) 1.29
Differential fates of biomolecules delivered to target cells via extracellular vesicles. Proc Natl Acad Sci U S A (2015) 1.27
Smallpox vaccines: targets of protective immunity. Immunol Rev (2011) 1.21
Phagocytosis of apoptotic cells in homeostasis. Nat Immunol (2015) 1.20
The vaccinia virus gene I2L encodes a membrane protein with an essential role in virion entry. J Virol (2008) 1.20
Blebbing confers resistance against cell lysis. Cell Death Differ (2010) 1.19
Cooperation between apoptotic and viable metacyclics enhances the pathogenesis of Leishmaniasis. PLoS One (2009) 1.17
Virus movements on the plasma membrane support infection and transmission between cells. PLoS Pathog (2009) 1.17
Macropinocytotic uptake and infection of human epithelial cells with species B2 adenovirus type 35. J Virol (2010) 1.17
Characterization of a newly identified 35-amino-acid component of the vaccinia virus entry/fusion complex conserved in all chordopoxviruses. J Virol (2009) 1.16
Appraising the apoptotic mimicry model and the role of phospholipids for poxvirus entry. Proc Natl Acad Sci U S A (2009) 1.15
Integrin β1 mediates vaccinia virus entry through activation of PI3K/Akt signaling. J Virol (2012) 1.14
Characterization of entry and infection of monocytic THP-1 cells by Kaposi's sarcoma associated herpesvirus (KSHV): role of heparan sulfate, DC-SIGN, integrins and signaling. Virology (2010) 1.13
CDC50 proteins are critical components of the human class-1 P4-ATPase transport machinery. J Biol Chem (2010) 1.13
Human cytomegalovirus entry into cells. Curr Opin Virol (2012) 1.12
A differential role for macropinocytosis in mediating entry of the two forms of vaccinia virus into dendritic cells. PLoS Pathog (2010) 1.11
A clathrin independent macropinocytosis-like entry mechanism used by bluetongue virus-1 during infection of BHK cells. PLoS One (2010) 1.11
Role of phosphatidylserine receptors in enveloped virus infection. J Virol (2014) 1.10
African swine fever virus uses macropinocytosis to enter host cells. PLoS Pathog (2012) 1.10
Virus activated filopodia promote human papillomavirus type 31 uptake from the extracellular matrix. Virology (2008) 1.10
Erythrophagocytosis of lead-exposed erythrocytes by renal tubular cells: possible role in lead-induced nephrotoxicity. Environ Health Perspect (2014) 1.09
Vaccinia virus exhibits cell-type-dependent entry characteristics. Virology (2009) 1.09
Rift valley fever virus infection of human cells and insect hosts is promoted by protein kinase C epsilon. PLoS One (2010) 1.09
Interaction of c-Cbl with myosin IIA regulates Bleb associated macropinocytosis of Kaposi's sarcoma-associated herpesvirus. PLoS Pathog (2010) 1.09
Cellular uptake of cyclotide MCoTI-I follows multiple endocytic pathways. J Control Release (2011) 1.08
Apoptotic cells activate NKT cells through T cell Ig-like mucin-like-1 resulting in airway hyperreactivity. J Immunol (2010) 1.08
Expression of the A56 and K2 proteins is sufficient to inhibit vaccinia virus entry and cell fusion. J Virol (2008) 1.07
Camouflage and misdirection: the full-on assault of ebola virus disease. Cell (2014) 1.07
Skin mast cells protect mice against vaccinia virus by triggering mast cell receptor S1PR2 and releasing antimicrobial peptides. J Immunol (2011) 1.06
Leishmania promastigotes lack phosphatidylserine but bind annexin V upon permeabilization or miltefosine treatment. PLoS One (2012) 1.06
Oncolytic viral purging of leukemic hematopoietic stem and progenitor cells with Myxoma virus. Cytokine Growth Factor Rev (2010) 1.06
Dynamin- and clathrin-dependent endocytosis in African swine fever virus entry. J Virol (2009) 1.06
Clathrin and LRP-1-independent constitutive endocytosis and recycling of uPAR. PLoS One (2008) 1.06
Different rotavirus strains enter MA104 cells through different endocytic pathways: the role of clathrin-mediated endocytosis. J Virol (2010) 1.06
Macrophages discriminate glycosylation patterns of apoptotic cell-derived microparticles. J Biol Chem (2011) 1.05
Poxvirus cell entry: how many proteins does it take? Viruses (2012) 1.05
Human genome-wide RNAi screen reveals a role for nuclear pore proteins in poxvirus morphogenesis. Proc Natl Acad Sci U S A (2013) 1.04
Vaccinia extracellular virions enter cells by macropinocytosis and acid-activated membrane rupture. EMBO J (2011) 1.04
Differential innate immune signaling in macrophages by wild type vaccinia mature virus and a mutant virus deleting A26 protein. J Virol (2017) 1.03
Vaccinia virus A25 and A26 proteins are fusion suppressors for mature virions and determine strain-specific virus entry pathways into HeLa, CHO-K1, and L cells. J Virol (2010) 1.03
Japanese encephalitis virus infects neuronal cells through a clathrin-independent endocytic mechanism. J Virol (2012) 1.03
Endocytosis of gene delivery vectors: from clathrin-dependent to lipid raft-mediated endocytosis. Mol Ther (2013) 1.03
The immune functions of phosphatidylserine in membranes of dying cells and microvesicles. Semin Immunopathol (2010) 1.03
Endocytosis of viruses and bacteria. Cold Spring Harb Perspect Biol (2014) 1.02
Filamentous influenza virus enters cells via macropinocytosis. J Virol (2012) 1.02
Rift Valley fever virus strain MP-12 enters mammalian host cells via caveola-mediated endocytosis. J Virol (2012) 1.02
Phosphatidylserine is a global immunosuppressive signal in efferocytosis, infectious disease, and cancer. Cell Death Differ (2016) 1.01
The membrane fusion step of vaccinia virus entry is cooperatively mediated by multiple viral proteins and host cell components. PLoS Pathog (2011) 1.01
Epstein-Barr virus transcytosis through polarized oral epithelial cells. J Virol (2013) 1.01
Determining the macropinocytic index of cells through a quantitative image-based assay. Nat Protoc (2014) 0.99
Histone deacetylase 8 is required for centrosome cohesion and influenza A virus entry. PLoS Pathog (2011) 0.99
Kaposi's Sarcoma Associated Herpesvirus Entry into Target Cells. Front Microbiol (2012) 0.98
A systematic analysis of host factors reveals a Med23-interferon-λ regulatory axis against herpes simplex virus type 1 replication. PLoS Pathog (2013) 0.98
Quality control in the endoplasmic reticulum. Nat Rev Mol Cell Biol (2003) 9.85
Virus entry: open sesame. Cell (2006) 6.33
Local actin polymerization and dynamin recruitment in SV40-induced internalization of caveolae. Science (2002) 5.41
Endosome maturation. EMBO J (2011) 5.22
How viruses enter animal cells. Science (2004) 4.35
Virus entry by macropinocytosis. Nat Cell Biol (2009) 3.87
Virus entry by endocytosis. Annu Rev Biochem (2010) 3.74
Endocytosis via caveolae. Traffic (2002) 3.41
Caveolin-stabilized membrane domains as multifunctional transport and sorting devices in endocytic membrane traffic. Cell (2004) 3.30
Clathrin- and caveolin-1-independent endocytosis: entry of simian virus 40 into cells devoid of caveolae. J Cell Biol (2005) 3.26
Rab7 associates with early endosomes to mediate sorting and transport of Semliki forest virus to late endosomes. PLoS Biol (2005) 2.95
Insider information: what viruses tell us about endocytosis. Curr Opin Cell Biol (2003) 2.80
Simian Virus 40 depends on ER protein folding and quality control factors for entry into host cells. Cell (2007) 2.57
Specific inhibition of diverse pathogens in human cells by synthetic microRNA-like oligonucleotides inferred from RNAi screens. Proc Natl Acad Sci U S A (2014) 2.25
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DC-SIGN as a receptor for phleboviruses. Cell Host Microbe (2011) 2.15
Single-cell analysis of population context advances RNAi screening at multiple levels. Mol Syst Biol (2012) 2.13
GM1 structure determines SV40-induced membrane invagination and infection. Nat Cell Biol (2009) 2.04
Single-particle tracking of murine polyoma virus-like particles on live cells and artificial membranes. Proc Natl Acad Sci U S A (2005) 2.01
Folding and dimerization of tick-borne encephalitis virus envelope proteins prM and E in the endoplasmic reticulum. J Virol (2002) 1.95
Nuclear import of hepatitis B virus capsids and release of the viral genome. Proc Natl Acad Sci U S A (2003) 1.93
Caveolin-1 is ubiquitinated and targeted to intralumenal vesicles in endolysosomes for degradation. J Cell Biol (2010) 1.83
Host cell factors and functions involved in vesicular stomatitis virus entry. J Virol (2008) 1.83
Effects of organelle shape on fluorescence recovery after photobleaching. Biophys J (2005) 1.77
Entry of human papillomavirus type 16 by actin-dependent, clathrin- and lipid raft-independent endocytosis. PLoS Pathog (2012) 1.76
TROSY-NMR reveals interaction between ERp57 and the tip of the calreticulin P-domain. Proc Natl Acad Sci U S A (2002) 1.70
Human papillomavirus type 16 entry: retrograde cell surface transport along actin-rich protrusions. PLoS Pathog (2008) 1.69
Contrasting functions of calreticulin and calnexin in glycoprotein folding and ER quality control. Mol Cell (2004) 1.62
N-glycolyl GM1 ganglioside as a receptor for simian virus 40. J Virol (2007) 1.59
Simulations of (an)isotropic diffusion on curved biological surfaces. Biophys J (2005) 1.57
ERp57 is a multifunctional thiol-disulfide oxidoreductase. J Biol Chem (2004) 1.55
High-speed nanoscopic tracking of the position and orientation of a single virus. Nat Methods (2009) 1.55
Architecture of respiratory syncytial virus revealed by electron cryotomography. Proc Natl Acad Sci U S A (2013) 1.51
Biogenesis of caveolae: stepwise assembly of large caveolin and cavin complexes. Traffic (2009) 1.50
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Echovirus 1 endocytosis into caveosomes requires lipid rafts, dynamin II, and signaling events. Mol Biol Cell (2004) 1.45
More than one glycan is needed for ER glucosidase II to allow entry of glycoproteins into the calnexin/calreticulin cycle. Mol Cell (2005) 1.45
BAP31 and BiP are essential for dislocation of SV40 from the endoplasmic reticulum to the cytosol. Nat Cell Biol (2011) 1.45
Vaccinia virus strains use distinct forms of macropinocytosis for host-cell entry. Proc Natl Acad Sci U S A (2010) 1.45
RNAi screening reveals proteasome- and Cullin3-dependent stages in vaccinia virus infection. Cell Rep (2012) 1.40
Entry of bunyaviruses into mammalian cells. Cell Host Microbe (2010) 1.40
Intracellular assembly and secretion of recombinant subviral particles from tick-borne encephalitis virus. J Virol (2003) 1.38
Host cell entry of respiratory syncytial virus involves macropinocytosis followed by proteolytic activation of the F protein. PLoS Pathog (2013) 1.35
Gulping rather than sipping: macropinocytosis as a way of virus entry. Curr Opin Microbiol (2012) 1.26
The transitional ER defines a boundary for quality control in the secretion of tsO45 VSV glycoprotein. Traffic (2002) 1.25
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Lymphocytic choriomeningitis virus uses a novel endocytic pathway for infectious entry via late endosomes. Virology (2008) 1.12
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Label-free optical detection and tracking of single virions bound to their receptors in supported membrane bilayers. Nano Lett (2007) 1.02
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Analyzing cotranslational protein folding and disulfide formation by diagonal sodium dodecyl sulfate-polyacrylamide gel electrophoresis. Methods Enzymol (2002) 0.85
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