Published in J Cell Biol on June 09, 2008
Plasticity of cell migration: a multiscale tuning model. J Cell Biol (2009) 5.82
Monoacylglycerol lipase regulates a fatty acid network that promotes cancer pathogenesis. Cell (2010) 5.47
Random versus directionally persistent cell migration. Nat Rev Mol Cell Biol (2009) 4.99
Protease-dependent versus -independent cancer cell invasion programs: three-dimensional amoeboid movement revisited. J Cell Biol (2009) 4.04
Role of cortical tension in bleb growth. Proc Natl Acad Sci U S A (2009) 3.08
Integrins in cell migration--the actin connection. J Cell Sci (2009) 2.88
Actin-myosin contractility is responsible for the reduced viability of dissociated human embryonic stem cells. Cell Stem Cell (2010) 2.69
Identification and characterization of a small molecule inhibitor of formin-mediated actin assembly. Chem Biol (2009) 2.57
The filamins: organizers of cell structure and function. Cell Adh Migr (2011) 2.50
Oncosome formation in prostate cancer: association with a region of frequent chromosomal deletion in metastatic disease. Cancer Res (2009) 2.07
A role for Rho GTPases and cell-cell adhesion in single-cell motility in vivo. Nat Cell Biol (2009) 2.05
Control of directed cell migration in vivo by membrane-to-cortex attachment. PLoS Biol (2010) 2.03
Contractility of the cell rear drives invasion of breast tumor cells in 3D Matrigel. Proc Natl Acad Sci U S A (2011) 1.98
Mechanisms guiding primordial germ cell migration: strategies from different organisms. Nat Rev Mol Cell Biol (2010) 1.88
Movers and shakers: cell cytoskeleton in cancer metastasis. Br J Pharmacol (2014) 1.74
Cyclodextrin protects podocytes in diabetic kidney disease. Diabetes (2013) 1.71
Distinct roles for paxillin and Hic-5 in regulating breast cancer cell morphology, invasion, and metastasis. Mol Biol Cell (2011) 1.54
Control of neural crest cell behavior and migration: Insights from live imaging. Cell Adh Migr (2011) 1.51
The role and regulation of blebs in cell migration. Curr Opin Cell Biol (2013) 1.48
Clinical relevance of microparticles from platelets and megakaryocytes. Curr Opin Hematol (2010) 1.43
In melanoma, beta-catenin is a suppressor of invasion. Oncogene (2011) 1.40
Cadherin-11 regulates protrusive activity in Xenopus cranial neural crest cells upstream of Trio and the small GTPases. Genes Dev (2009) 1.37
Mesenchymal stem cell mechanics from the attached to the suspended state. Biophys J (2010) 1.31
Rac1 drives melanoblast organization during mouse development by orchestrating pseudopod- driven motility and cell-cycle progression. Dev Cell (2011) 1.29
Redox regulation of cell migration and adhesion. Trends Cell Biol (2011) 1.28
Control of cortical rigidity by the cytoskeleton: emerging roles for septins. Cytoskeleton (Hoboken) (2010) 1.24
A systematic analysis of the PARP protein family identifies new functions critical for cell physiology. Nat Commun (2013) 1.19
Interstitial cell migration: integrin-dependent and alternative adhesion mechanisms. Cell Tissue Res (2009) 1.16
Mesenchymal stem cells transmigrate between and directly through tumor necrosis factor-α-activated endothelial cells via both leukocyte-like and novel mechanisms. Stem Cells (2012) 1.14
RhoA triggers a specific signaling pathway that generates transforming microvesicles in cancer cells. Oncogene (2012) 1.13
Mutations in the gene that encodes the F-actin binding protein anillin cause FSGS. J Am Soc Nephrol (2014) 1.12
The septin cytoskeleton facilitates membrane retraction during motility and blebbing. J Cell Biol (2012) 1.11
Rac and Rho driving tumor invasion: who's at the wheel? Genome Biol (2009) 1.08
FilGAP, a Rho/Rho-associated protein kinase-regulated GTPase-activating protein for Rac, controls tumor cell migration. Mol Biol Cell (2012) 1.08
Removal of the mechanoprotective influence of the cytoskeleton reveals PIEZO1 is gated by bilayer tension. Nat Commun (2016) 1.06
Combination of MEK and SRC inhibition suppresses melanoma cell growth and invasion. Oncogene (2012) 1.04
Formation and propagation of tau oligomeric seeds. Front Neurol (2013) 1.04
The ADP-ribosylation domain of Pseudomonas aeruginosa ExoS is required for membrane bleb niche formation and bacterial survival within epithelial cells. Infect Immun (2010) 1.03
Impact of actin rearrangement and degranulation on the membrane structure of primary mast cells: a combined atomic force and laser scanning confocal microscopy investigation. Biophys J (2009) 1.03
Accumulation of vesicle-associated human tau in distal dendrites drives degeneration and tau secretion in an in situ cellular tauopathy model. Int J Alzheimers Dis (2012) 1.02
Compression and dilation of the membrane-cortex layer generates rapid changes in cell shape. J Cell Biol (2013) 1.02
Bradykinin enhances invasion of malignant glioma into the brain parenchyma by inducing cells to undergo amoeboid migration. J Physiol (2014) 1.02
αE-catenin regulates cell-cell adhesion and membrane blebbing during zebrafish epiboly. Development (2011) 1.02
PtdIns(3,4)P2 instigates focal adhesions to generate podosomes. Cell Adh Migr (2009) 1.00
Constitutively active ezrin increases membrane tension, slows migration, and impedes endothelial transmigration of lymphocytes in vivo in mice. Blood (2011) 1.00
Completion of the epithelial to mesenchymal transition in zebrafish mesoderm requires Spadetail. Dev Biol (2011) 1.00
Dynamical organization of the cytoskeletal cortex probed by micropipette aspiration. Proc Natl Acad Sci U S A (2010) 0.99
Apoptotic cells are cleared by directional migration and elmo1- dependent macrophage engulfment. Curr Biol (2012) 0.99
Aquaporin-1 facilitates angiogenic invasion in the pathological neovasculature that accompanies cirrhosis. Hepatology (2010) 0.98
Coronin-1C is a novel biomarker for hepatocellular carcinoma invasive progression identified by proteomics analysis and clinical validation. J Exp Clin Cancer Res (2010) 0.97
Neurokinin 1 receptor mediates membrane blebbing in HEK293 cells through a Rho/Rho-associated coiled-coil kinase-dependent mechanism. J Biol Chem (2009) 0.95
Focus on Extracellular Vesicles: New Frontiers of Cell-to-Cell Communication in Cancer. Int J Mol Sci (2016) 0.95
Identification of a novel Bves function: regulation of vesicular transport. EMBO J (2010) 0.93
Diaphanous-related formin 2 and profilin I are required for gastrulation cell movements. PLoS One (2008) 0.93
A computational model of bleb formation. Math Med Biol (2012) 0.92
Interference with endothelial cell function by JG-03-14, an agent that binds to the colchicine site on microtubules. Biochem Pharmacol (2009) 0.92
The three-way switch operation of Rac1/RhoA GTPase-based circuit controlling amoeboid-hybrid-mesenchymal transition. Sci Rep (2014) 0.92
G-protein-coupled receptor signaling and polarized actin dynamics drive cell-in-cell invasion. Elife (2014) 0.92
Reconstruction of active regular motion in amoeba extract: dynamic cooperation between sol and gel states. PLoS One (2013) 0.91
Substance P induces rapid and transient membrane blebbing in U373MG cells in a p21-activated kinase-dependent manner. PLoS One (2011) 0.91
Open source software for quantification of cell migration, protrusions, and fluorescence intensities. J Cell Biol (2015) 0.91
KSHV-TK is a tyrosine kinase that disrupts focal adhesions and induces Rho-mediated cell contraction. EMBO J (2014) 0.90
How blebs and pseudopods cooperate during chemotaxis. Proc Natl Acad Sci U S A (2014) 0.89
Hypoxia induces a lipogenic cancer cell phenotype via HIF1α-dependent and -independent pathways. Oncotarget (2015) 0.89
Mapping the complex morphology of cell interactions with nanowire substrates using FIB-SEM. PLoS One (2013) 0.88
Multiphase flow models of biogels from crawling cells to bacterial biofilms. HFSP J (2010) 0.88
Actomyosin-based self-organization of cell internalization during C. elegans gastrulation. BMC Biol (2012) 0.87
Regulation of cell adhesions and motility during initiation of neural crest migration. Curr Opin Neurobiol (2010) 0.86
Enhanced shedding of extracellular vesicles from amoeboid prostate cancer cells: potential effects on the tumor microenvironment. Cancer Biol Ther (2014) 0.86
Effect of RGD functionalization and stiffness modulation of polyelectrolyte multilayer films on muscle cell differentiation. Acta Biomater (2012) 0.86
Applications of atomic force microscopy in biophysical chemistry of cells. J Phys Chem B (2010) 0.86
A cell-ECM screening method to predict breast cancer metastasis. Integr Biol (Camb) (2015) 0.85
UV irradiation/cold shock-mediated apoptosis is switched to bubbling cell death at low temperatures. Oncotarget (2015) 0.85
Targeting Rho-GTPases in immune cell migration and inflammation. Br J Pharmacol (2014) 0.85
A RhoA and Rnd3 cycle regulates actin reassembly during membrane blebbing. Proc Natl Acad Sci U S A (2016) 0.85
JosD1, a membrane-targeted deubiquitinating enzyme, is activated by ubiquitination and regulates membrane dynamics, cell motility, and endocytosis. J Biol Chem (2013) 0.85
Effects of dimethyl sulfoxide in cholesterol-containing lipid membranes: a comparative study of experiments in silico and with cells. PLoS One (2012) 0.85
Electric field exposure triggers and guides formation of pseudopod-like blebs in U937 monocytes. J Membr Biol (2012) 0.85
Fluxes of water through aquaporin 9 weaken membrane-cytoskeleton anchorage and promote formation of membrane protrusions. PLoS One (2013) 0.84
Vincristine enhances amoeboid-like motility via GEF-H1/RhoA/ROCK/Myosin light chain signaling in MKN45 cells. BMC Cancer (2012) 0.84
ADP ribosylation factor 6 (Arf6) acts through FilGAP protein to down-regulate Rac protein and regulates plasma membrane blebbing. J Biol Chem (2014) 0.84
ROCK1 and LIMK2 interact in spread but not blebbing cancer cells. PLoS One (2008) 0.83
Arp2/3 inhibition induces amoeboid-like protrusions in MCF10A epithelial cells by reduced cytoskeletal-membrane coupling and focal adhesion assembly. PLoS One (2014) 0.83
Epitaxially grown collagen fibrils reveal diversity in contact guidance behavior among cancer cells. Langmuir (2014) 0.83
Trading in your spindles for blebs: the amoeboid tumor cell phenotype in prostate cancer. Asian J Androl (2014) 0.83
Loss of Cell Surface CD47 Clustering Formation and Binding Avidity to SIRPα Facilitate Apoptotic Cell Clearance by Macrophages. J Immunol (2015) 0.83
Matrix-bound PAI-1 supports cell blebbing via RhoA/ROCK1 signaling. PLoS One (2012) 0.83
Cellular regulation of extension and retraction of pseudopod-like blebs produced by nanosecond pulsed electric field (nsPEF). Cell Biochem Biophys (2014) 0.82
The NK-1 receptor is expressed in human leukemia and is involved in the antitumor action of aprepitant and other NK-1 receptor antagonists on acute lymphoblastic leukemia cell lines. Invest New Drugs (2010) 0.82
Differing and isoform-specific roles for the formin DIAPH3 in plasma membrane blebbing and filopodia formation. Cell Res (2011) 0.82
Myosin light chain kinase and Src control membrane dynamics in volume recovery from cell swelling. Mol Biol Cell (2011) 0.82
Lactobacilli antagonize the growth, motility, and adherence of Brachyspira pilosicoli: a potential intervention against avian intestinal spirochetosis. Appl Environ Microbiol (2011) 0.81
Quantitative Multiscale Cell Imaging in Controlled 3D Microenvironments. Dev Cell (2016) 0.81
An mDia2/ROCK signaling axis regulates invasive egress from epithelial ovarian cancer spheroids. PLoS One (2014) 0.81
Light generation of intracellular Ca(2+) signals by a genetically encoded protein BACCS. Nat Commun (2015) 0.81
Anthrolysin O and fermentation products mediate the toxicity of Bacillus anthracis to lung epithelial cells under microaerobic conditions. FEMS Immunol Med Microbiol (2010) 0.81
Absence of the basement membrane component nidogen 2, but not of nidogen 1, results in increased lung metastasis in mice. J Histochem Cytochem (2012) 0.80
Reviewing and reconsidering invasion assays in head and neck cancer. Oral Oncol (2014) 0.80
EGF-like factors induce expansion of the cumulus cell-oocyte complexes by activating calpain-mediated cell movement. Endocrinology (2012) 0.80
An Engineered Split Intein for Photoactivated Protein Trans-Splicing. PLoS One (2015) 0.80
Differing modes of tumour cell invasion have distinct requirements for Rho/ROCK signalling and extracellular proteolysis. Nat Cell Biol (2003) 7.93
Compensation mechanism in tumor cell migration: mesenchymal-amoeboid transition after blocking of pericellular proteolysis. J Cell Biol (2003) 7.89
Rac downregulates Rho activity: reciprocal balance between both GTPases determines cellular morphology and migratory behavior. J Cell Biol (1999) 6.01
Membrane blebbing during apoptosis results from caspase-mediated activation of ROCK I. Nat Cell Biol (2001) 5.67
Mechanism and function of formins in the control of actin assembly. Annu Rev Biochem (2007) 5.36
Vaccinia virus uses macropinocytosis and apoptotic mimicry to enter host cells. Science (2008) 5.04
The many faces of actin: matching assembly factors with cellular structures. Nat Cell Biol (2007) 4.90
Caspase-3-mediated cleavage of ROCK I induces MLC phosphorylation and apoptotic membrane blebbing. Nat Cell Biol (2001) 4.74
Actin-binding protein requirement for cortical stability and efficient locomotion. Science (1992) 4.66
Phosphatidylinositol 4,5-bisphosphate functions as a second messenger that regulates cytoskeleton-plasma membrane adhesion. Cell (2000) 4.45
Reassembly of contractile actin cortex in cell blebs. J Cell Biol (2006) 4.31
Rapid secretion of interleukin-1beta by microvesicle shedding. Immunity (2001) 4.23
FilGAP, a Rho- and ROCK-regulated GAP for Rac binds filamin A to control actin remodelling. Nat Cell Biol (2006) 4.23
Non-equilibration of hydrostatic pressure in blebbing cells. Nature (2005) 4.08
Prespecification and plasticity: shifting mechanisms of cell migration. Curr Opin Cell Biol (2004) 3.78
Cell migration in 3D matrix. Curr Opin Cell Biol (2005) 3.63
Mechanisms of cancer cell invasion. Curr Opin Genet Dev (2005) 3.47
Migration of zebrafish primordial germ cells: a role for myosin contraction and cytoplasmic flow. Dev Cell (2006) 3.39
Mechanisms, mechanics and function of epithelial-mesenchymal transitions in early development. Mech Dev (2003) 3.25
Staying in shape with formins. Dev Cell (2006) 3.21
Life and times of a cellular bleb. Biophys J (2007) 3.05
Actin polymerization and intracellular solvent flow in cell surface blebbing. J Cell Biol (1995) 2.58
Mitosis in cultures of newt tissues. IV. The cell surface in late anaphase and the movements of ribonucleoprotein. Exp Cell Res (1955) 2.48
Continuous membrane-cytoskeleton adhesion requires continuous accommodation to lipid and cytoskeleton dynamics. Annu Rev Biophys Biomol Struct (2006) 2.39
Formins: signaling effectors for assembly and polarization of actin filaments. J Cell Sci (2003) 2.31
PDK1 regulates cancer cell motility by antagonising inhibition of ROCK1 by RhoE. Nat Cell Biol (2008) 2.27
Loss of p53 promotes RhoA-ROCK-dependent cell migration and invasion in 3D matrices. J Cell Biol (2007) 2.17
Dissection of amoeboid movement into two mechanically distinct modes. J Cell Sci (2006) 1.90
Surface activity and locomotion of Fundulus deep cells during blastula and gastrula stages. Dev Biol (1973) 1.84
Positive feedback between Dia1, LARG, and RhoA regulates cell morphology and invasion. Genes Dev (2007) 1.77
Attachment and spreading of cells in culture. Exp Cell Res (1961) 1.71
Rac1-null mouse embryonic fibroblasts are motile and respond to platelet-derived growth factor. Mol Biol Cell (2006) 1.60
MARCKS regulates membrane ruffling and cell spreading. Curr Biol (1997) 1.56
Dia-interacting protein modulates formin-mediated actin assembly at the cell cortex. Curr Biol (2007) 1.56
P2X7 receptor-dependent blebbing and the activation of Rho-effector kinases, caspases, and IL-1 beta release. J Immunol (2003) 1.52
Cellular movement and contact in sea urchin morphogenesis. Biol Rev Camb Philos Soc (1967) 1.43
Dynamic modes of the cortical actomyosin gel during cell locomotion and division. Trends Cell Biol (2005) 1.42
Blebbing of Dictyostelium cells in response to chemoattractant. Exp Cell Res (2006) 1.39
Loss of PIP5KIgamma, unlike other PIP5KI isoforms, impairs the integrity of the membrane cytoskeleton in murine megakaryocytes. J Clin Invest (2008) 1.33
Cytologic studies with the phase microscope; morphologic changes associated with the death of cells in vitro and in vivo. Am J Pathol (1948) 1.32
The micromorphology of zeiotic blebs in cultured human epithelial (HEp) cells. Exp Cell Res (1967) 1.24
Pseudomonas aeruginosa induces membrane blebs in epithelial cells, which are utilized as a niche for intracellular replication and motility. Infect Immun (2008) 1.22
P2X7 nucleotide receptors mediate blebbing in osteoblasts through a pathway involving lysophosphatidic acid. J Biol Chem (2006) 1.21
Rho overexpression leads to mitosis-associated detachment of cells from epithelial sheets: a link to the mechanism of cancer dissemination. Proc Natl Acad Sci U S A (2004) 1.19
Surface specializations of Fundulus cells and their relation to cell movements during gastrulation. J Cell Biol (1967) 1.18
The actin-myosin cytoskeleton mediates reversible agonist-induced membrane blebbing. J Cell Sci (1998) 1.13
SH4-domain-induced plasma membrane dynamization promotes bleb-associated cell motility. J Cell Sci (2007) 1.07
The micromorphology of FL and primary human amnion cells following exposure to high hydrostatic pressure. Cancer Res (1961) 1.06
Protrusive activity quantitatively determines the rate and direction of cell locomotion. Cell Motil Cytoskeleton (1996) 1.04
Regulation of plasma membrane blebbing by the cytoskeleton. J Cell Biochem (1999) 1.01
Src-mediated cortactin phosphorylation regulates actin localization and injurious blebbing in acinar cells. Mol Biol Cell (2008) 0.98
RacB regulates cytoskeletal function in Dictyostelium spp. Eukaryot Cell (2003) 0.94
Independence of plasma membrane blebbing from other biochemical and biological characteristics of apoptotic cells. J Biochem (2002) 0.92
An activated Rac mutant functions as a dominant negative for membrane ruffling. Oncogene (1998) 0.91
Some clues as to the formation of protrusions by Fundulus deep cells. J Cell Sci (1977) 0.88
THE EFFECT OF HYPOTONIC AND HYPERTONIC SOLUTIONS ON FIBROBLASTS OF THE EMBRYONIC CHICK HEART IN VITRO. J Exp Med (1919) 0.87
Changes in surface extensibility of Fundulus deep cells during early development. J Cell Sci (1973) 0.87
Fibroblast-led collective invasion of carcinoma cells with differing roles for RhoGTPases in leading and following cells. Nat Cell Biol (2007) 7.20
Staying in shape with formins. Dev Cell (2006) 3.21
Nucleating actin for invasion. Nat Rev Cancer (2011) 2.22
Dia1 and IQGAP1 interact in cell migration and phagocytic cup formation. J Cell Biol (2007) 2.15
Nuclear actin network assembly by formins regulates the SRF coactivator MAL. Science (2013) 2.13
Positive feedback between Dia1, LARG, and RhoA regulates cell morphology and invasion. Genes Dev (2007) 1.77
Integrin trafficking regulated by Rab21 is necessary for cytokinesis. Dev Cell (2008) 1.70
Get to grips: steering local actin dynamics with IQGAPs. EMBO Rep (2007) 1.68
Receptor-dependent RhoA activation in G12/G13-deficient cells: genetic evidence for an involvement of Gq/G11. J Biol Chem (2003) 1.57
Galpha12/13 is essential for directed cell migration and localized Rho-Dia1 function. J Biol Chem (2005) 1.51
HIV-1 Nef interferes with host cell motility by deregulation of Cofilin. Cell Host Microbe (2009) 1.50
SCAI acts as a suppressor of cancer cell invasion through the transcriptional control of beta1-integrin. Nat Cell Biol (2009) 1.42
The Diaphanous-related Formin FHOD1 associates with ROCK1 and promotes Src-dependent plasma membrane blebbing. J Biol Chem (2008) 1.20
LARG and mDia1 link Galpha12/13 to cell polarity and microtubule dynamics. Mol Biol Cell (2007) 1.20
Matrix metalloproteinases 2 and 9 mediate epidermal growth factor receptor transactivation by gonadotropin-releasing hormone. J Biol Chem (2003) 1.11
SH4-domain-induced plasma membrane dynamization promotes bleb-associated cell motility. J Cell Sci (2007) 1.07
Guanine nucleotide-binding proteins of the G12 family shape immune functions by controlling CD4+ T cell adhesiveness and motility. Immunity (2009) 1.03
The sphingosine 1-phosphate receptor S1P4 regulates cell shape and motility via coupling to Gi and G12/13. J Cell Biochem (2003) 1.02
Nef does not inhibit F-actin remodelling and HIV-1 cell-cell transmission at the T lymphocyte virological synapse. Eur J Cell Biol (2010) 0.93
SnapShot: Formins. Cell (2010) 0.91
Regulation of myocardin-related transcriptional coactivators through cofactor interactions in differentiation and cancer. Cell Cycle (2009) 0.84
Functional interaction of SCAI with the SWI/SNF complex for transcription and tumor cell invasion. PLoS One (2013) 0.82
Differing and isoform-specific roles for the formin DIAPH3 in plasma membrane blebbing and filopodia formation. Cell Res (2011) 0.82
A GBD uncovered: the FHOD1 N terminus is formin'. Structure (2008) 0.80
Detection of activated Rho in fixed Xenopus tissue. Dev Dyn (2009) 0.79
Correction: Actin visualization at a glance. J Cell Sci (2017) 0.76
Pharmacological inhibition of actin assembly to target tumor cell motility. Rev Physiol Biochem Pharmacol (2014) 0.75