Published in Curr Opin Cell Biol on April 23, 2008
Linking DNA methylation and histone modification: patterns and paradigms. Nat Rev Genet (2009) 12.08
Mechanisms of polycomb gene silencing: knowns and unknowns. Nat Rev Mol Cell Biol (2009) 9.29
Genome-wide identification of polycomb-associated RNAs by RIP-seq. Mol Cell (2010) 6.88
Comprehensive analysis of the chromatin landscape in Drosophila melanogaster. Nature (2010) 6.87
Role of the polycomb protein EED in the propagation of repressive histone marks. Nature (2009) 6.62
CpG islands influence chromatin structure via the CpG-binding protein Cfp1. Nature (2010) 4.86
Chromatin structure and gene expression programs of human embryonic and induced pluripotent stem cells. Cell Stem Cell (2010) 4.59
Lessons from X-chromosome inactivation: long ncRNA as guides and tethers to the epigenome. Genes Dev (2009) 4.20
YY1 tethers Xist RNA to the inactive X nucleation center. Cell (2011) 4.06
Noncoding RNA in development. Mamm Genome (2008) 3.42
Functional anatomy of polycomb and trithorax chromatin landscapes in Drosophila embryos. PLoS Biol (2009) 3.24
Inhibition of natural antisense transcripts in vivo results in gene-specific transcriptional upregulation. Nat Biotechnol (2012) 3.07
H3K36 methylation antagonizes PRC2-mediated H3K27 methylation. J Biol Chem (2011) 2.63
Polycomb complexes act redundantly to repress genomic repeats and genes. Genes Dev (2010) 2.63
A PHD-polycomb repressive complex 2 triggers the epigenetic silencing of FLC during vernalization. Proc Natl Acad Sci U S A (2008) 2.61
SUMO-specific protease 2 is essential for suppression of polycomb group protein-mediated gene silencing during embryonic development. Mol Cell (2010) 2.52
Genomic variation in natural populations of Drosophila melanogaster. Genetics (2012) 2.33
Polycomb proteins remain bound to chromatin and DNA during DNA replication in vitro. Cell (2009) 2.20
Drosophila O-GlcNAc transferase (OGT) is encoded by the Polycomb group (PcG) gene, super sex combs (sxc). Proc Natl Acad Sci U S A (2009) 2.12
Regulation of imprinted gene expression in Arabidopsis endosperm. Proc Natl Acad Sci U S A (2011) 2.01
Regulatory interactions between RNA and polycomb repressive complex 2. Mol Cell (2014) 1.97
Polycomb associates genome-wide with a specific RNA polymerase II variant, and regulates metabolic genes in ESCs. Cell Stem Cell (2012) 1.80
AEBP2 as a potential targeting protein for Polycomb Repression Complex PRC2. Nucleic Acids Res (2009) 1.79
Polycomb repressive complex 2 controls the embryo-to-seedling phase transition. PLoS Genet (2011) 1.79
Modifications of RNA polymerase II are pivotal in regulating gene expression states. EMBO Rep (2009) 1.78
Spatial epigenetic control of mono- and bistable gene expression. PLoS Biol (2010) 1.71
Derepression of Polycomb targets during pancreatic organogenesis allows insulin-producing beta-cells to adopt a neural gene activity program. Genome Res (2010) 1.68
Epigenetic regulation of latent HSV-1 gene expression. Biochim Biophys Acta (2010) 1.65
Modeling of epigenome dynamics identifies transcription factors that mediate Polycomb targeting. Genome Res (2012) 1.54
The polycomb group protein Bmi1 binds to the herpes simplex virus 1 latent genome and maintains repressive histone marks during latency. J Virol (2009) 1.53
Epigenetics: A New Bridge between Nutrition and Health. Adv Nutr (2010) 1.51
O-GlcNAc cycling: emerging roles in development and epigenetics. Semin Cell Dev Biol (2010) 1.50
Linker histone H1 is essential for Drosophila development, the establishment of pericentric heterochromatin, and a normal polytene chromosome structure. Genes Dev (2009) 1.50
Temporal fate specification and neural progenitor competence during development. Nat Rev Neurosci (2013) 1.48
Recognition of UbcH5c and the nucleosome by the Bmi1/Ring1b ubiquitin ligase complex. EMBO J (2011) 1.48
Epigenetic modifications in plants: an evolutionary perspective. Curr Opin Plant Biol (2011) 1.45
A chromatin insulator driving three-dimensional Polycomb response element (PRE) contacts and Polycomb association with the chromatin fiber. Proc Natl Acad Sci U S A (2011) 1.45
The X as model for RNA's niche in epigenomic regulation. Cold Spring Harb Perspect Biol (2010) 1.43
Polycomb group proteins as epigenetic mediators of neuroprotection in ischemic tolerance. Sci Signal (2010) 1.31
Additional sex combs-like 1 belongs to the enhancer of trithorax and polycomb group and genetically interacts with Cbx2 in mice. Dev Biol (2009) 1.30
Compaction of chromatin by diverse Polycomb group proteins requires localized regions of high charge. Genes Dev (2011) 1.26
Cohesin and polycomb proteins functionally interact to control transcription at silenced and active genes. PLoS Genet (2013) 1.25
The roles of EZH2 in cell lineage commitment. Am J Transl Res (2011) 1.24
Endoreplication controls cell fate maintenance. PLoS Genet (2010) 1.22
Transcriptional gene silencing through epigenetic changes mediated by non-coding RNAs. Curr Opin Mol Ther (2010) 1.20
An Ehrlichia chaffeensis tandem repeat protein interacts with multiple host targets involved in cell signaling, transcriptional regulation, and vesicle trafficking. Infect Immun (2009) 1.20
The yin and yang of chromatin spatial organization. Genome Biol (2010) 1.20
Transcriptional silencing by polycomb-group proteins. Cold Spring Harb Perspect Biol (2014) 1.19
Polycomb group targeting through different binding partners of RING1B C-terminal domain. Structure (2010) 1.19
STAT6-mediated displacement of polycomb by trithorax complex establishes long-term maintenance of GATA3 expression in T helper type 2 cells. J Exp Med (2010) 1.18
Old and new stories: revelations from functional analysis of the bovine mammary transcriptome during the lactation cycle. PLoS One (2012) 1.13
Comparative RNA-seq analysis in the unsequenced axolotl: the oncogene burst highlights early gene expression in the blastema. PLoS Comput Biol (2013) 1.11
Integrated transcriptomic and epigenomic analysis of primary human lung epithelial cell differentiation. PLoS Genet (2013) 1.09
RYBP represses endogenous retroviruses and preimplantation- and germ line-specific genes in mouse embryonic stem cells. Mol Cell Biol (2012) 1.08
Genome-wide chromatin occupancy analysis reveals a role for ASH2 in transcriptional pausing. Nucleic Acids Res (2011) 1.08
Genome-wide analysis of local chromatin packing in Arabidopsis thaliana. Genome Res (2014) 1.06
Genome-wide DNA methylation maps in follicular lymphoma cells determined by methylation-enriched bisulfite sequencing. PLoS One (2010) 1.06
Epigenetic mechanisms of Groucho/Grg/TLE mediated transcriptional repression. Mol Cell (2011) 1.05
EZH2 regulates neuronal differentiation of mesenchymal stem cells through PIP5K1C-dependent calcium signaling. J Biol Chem (2011) 1.03
The role of epigenetics in the biology of multiple myeloma. Blood Cancer J (2014) 0.99
Transcriptional regulation of Arabidopsis LEAFY COTYLEDON2 involves RLE, a cis-element that regulates trimethylation of histone H3 at lysine-27. Plant Cell (2011) 0.99
SFMBT1 functions with LSD1 to regulate expression of canonical histone genes and chromatin-related factors. Genes Dev (2013) 0.97
Are we there yet? Initial targeting of the Male-Specific Lethal and Polycomb group chromatin complexes in Drosophila. Open Biol (2014) 0.96
The E3 ubiquitin-ligase Bmi1/Ring1A controls the proteasomal degradation of Top2alpha cleavage complex - a potentially new drug target. PLoS One (2009) 0.96
Polycomb repressor complex 2 regulates HOXA9 and HOXA10, activating ID2 in NK/T-cell lines. Mol Cancer (2010) 0.96
Epigenetic regulation of gene programs by EMF1 and EMF2 in Arabidopsis. Plant Physiol (2009) 0.95
Control of flowering and cell fate by LIF2, an RNA binding partner of the polycomb complex component LHP1. PLoS One (2011) 0.95
PU.1 binds to a distal regulatory element that is necessary for B cell-specific expression of CIITA. J Immunol (2010) 0.95
Spps, a Drosophila Sp1/KLF family member, binds to PREs and is required for PRE activity late in development. Development (2010) 0.95
Functional O-GlcNAc modifications: implications in molecular regulation and pathophysiology. Crit Rev Biochem Mol Biol (2014) 0.94
Genome-wide recruitment to Polycomb-modified chromatin and activity regulation of the synovial sarcoma oncogene SYT-SSX2. BMC Genomics (2012) 0.93
Selective targeting of histone methylation. Cell Cycle (2011) 0.92
Synergistic repression of the embryonic programme by SET DOMAIN GROUP 8 and EMBRYONIC FLOWER 2 in Arabidopsis seedlings. J Exp Bot (2011) 0.92
Comparative analyses of H3K4 and H3K27 trimethylations between the mouse cerebrum and testis. Genomics Proteomics Bioinformatics (2012) 0.91
Histone methyltransferases and demethylases: regulators in balancing osteogenic and adipogenic differentiation of mesenchymal stem cells. Int J Oral Sci (2015) 0.90
Characterization of new regulatory elements within the Drosophila bithorax complex. Nucleic Acids Res (2008) 0.90
Characterization of the polycomb group response elements of the Drosophila melanogaster invected Locus. Mol Cell Biol (2009) 0.89
Polycomb group gene OsFIE2 regulates rice (Oryza sativa) seed development and grain filling via a mechanism distinct from Arabidopsis. PLoS Genet (2013) 0.89
Different gene-specific mechanisms determine the 'revised-response' memory transcription patterns of a subset of A. thaliana dehydration stress responding genes. Nucleic Acids Res (2014) 0.88
Loss of EGFR signaling regulated miR-203 promotes prostate cancer bone metastasis and tyrosine kinase inhibitors resistance. Oncotarget (2014) 0.88
Mechanisms guiding Polycomb activities during gene silencing in Arabidopsis thaliana. Front Plant Sci (2013) 0.88
The growth-suppressive function of the polycomb group protein polyhomeotic is mediated by polymerization of its sterile alpha motif (SAM) domain. J Biol Chem (2012) 0.88
Quantitative analysis of polycomb response elements (PREs) at identical genomic locations distinguishes contributions of PRE sequence and genomic environment. Epigenetics Chromatin (2011) 0.88
Cbx4 regulates the proliferation of thymic epithelial cells and thymus function. Development (2013) 0.88
Dual function of polycomb group proteins in differentiated murine T helper (CD4+) cells. J Mol Signal (2011) 0.88
Polycomb domain formation depends on short and long distance regulatory cues. PLoS One (2013) 0.87
The Arabidopsis GAGA-Binding Factor BASIC PENTACYSTEINE6 Recruits the POLYCOMB-REPRESSIVE COMPLEX1 Component LIKE HETEROCHROMATIN PROTEIN1 to GAGA DNA Motifs. Plant Physiol (2015) 0.86
Dissecting the Roles of Polycomb Repressive Complex 2 Subunits in the Control of Skin Development. J Invest Dermatol (2016) 0.86
Mendelian disorders of the epigenetic machinery: tipping the balance of chromatin states. Annu Rev Genomics Hum Genet (2014) 0.86
The histone H3-K27 demethylase Utx regulates HOX gene expression in Drosophila in a temporally restricted manner. Development (2013) 0.86
A genetic approach to the recruitment of PRC2 at the HoxD locus. PLoS Genet (2013) 0.85
Molecular genetic analysis of Suppressor 2 of zeste identifies key functional domains. Genetics (2009) 0.85
Chromatin domain boundary element search tool for Drosophila. Nucleic Acids Res (2012) 0.84
Polycomb repressive complex 2 (PRC2) protein ESC regulates insect developmental timing by mediating H3K27me3 and activating prothoracicotropic hormone gene expression. J Biol Chem (2013) 0.84
Highly conserved ENY2/Sus1 protein binds to Drosophila CTCF and is required for barrier activity. Epigenetics (2014) 0.84
Combinatorial interactions are required for the efficient recruitment of pho repressive complex (PhoRC) to polycomb response elements. PLoS Genet (2014) 0.83
Expression of vernalization responsive genes in wheat is associated with histone H3 trimethylation. Mol Genet Genomics (2012) 0.82
Regulation of cellular chromatin state: insights from quiescence and differentiation. Organogenesis (2010) 0.82
The Drosophila eve insulator Homie promotes eve expression and protects the adjacent gene from repression by polycomb spreading. PLoS Genet (2013) 0.82
Polycomb-Mediated Repression and Sonic Hedgehog Signaling Interact to Regulate Merkel Cell Specification during Skin Development. PLoS Genet (2016) 0.82
Identification of functional elements and regulatory circuits by Drosophila modENCODE. Science (2010) 12.39
Drosophila enhancer of Zeste/ESC complexes have a histone H3 methyltransferase activity that marks chromosomal Polycomb sites. Cell (2002) 12.28
Polycomb silencing mechanisms and the management of genomic programmes. Nat Rev Genet (2007) 7.61
Comprehensive analysis of the chromatin landscape in Drosophila melanogaster. Nature (2010) 6.87
Role of the polycomb protein EED in the propagation of repressive histone marks. Nature (2009) 6.62
Genome-wide analysis of Polycomb targets in Drosophila melanogaster. Nat Genet (2006) 6.48
An assessment of histone-modification antibody quality. Nat Struct Mol Biol (2010) 3.72
Polycomb silencing blocks transcription initiation. Mol Cell (2004) 2.96
Ezh2 requires PHF1 to efficiently catalyze H3 lysine 27 trimethylation in vivo. Mol Cell Biol (2008) 2.93
Association of cohesin and Nipped-B with transcriptionally active regions of the Drosophila melanogaster genome. Chromosoma (2007) 2.73
CHD1 motor protein is required for deposition of histone variant H3.3 into chromatin in vivo. Science (2007) 2.71
Alternative epigenetic chromatin states of polycomb target genes. PLoS Genet (2010) 2.15
Plasticity in patterns of histone modifications and chromosomal proteins in Drosophila heterochromatin. Genome Res (2010) 1.87
Polycomb complexes and the propagation of the methylation mark at the Drosophila ubx gene. J Biol Chem (2006) 1.78
Nature and function of insulator protein binding sites in the Drosophila genome. Genome Res (2012) 1.77
A new world of Polycombs: unexpected partnerships and emerging functions. Nat Rev Genet (2013) 1.67
Regulation of the Drosophila Enhancer of split and invected-engrailed gene complexes by sister chromatid cohesion proteins. PLoS One (2009) 1.58
An endogenous Su(Hw) insulator separates the yellow gene from the Achaete-scute gene complex in Drosophila. Development (2003) 1.52
Insulators, not Polycomb response elements, are required for long-range interactions between Polycomb targets in Drosophila melanogaster. Mol Cell Biol (2010) 1.47
The Drosophila trithorax protein is a coactivator required to prevent re-establishment of polycomb silencing. Development (2002) 1.45
ESC, ESCL and their roles in Polycomb Group mechanisms. Mech Dev (2008) 1.23
Characteristic low density and shear sensitivity of cross-linked chromatin containing polycomb complexes. Mol Cell Biol (2005) 1.22
The Mcp element mediates stable long-range chromosome-chromosome interactions in Drosophila. Mol Biol Cell (2006) 1.21
Sequence-specific targeting of dosage compensation in Drosophila favors an active chromatin context. PLoS Genet (2012) 1.04
Insulators target active genes to transcription factories and polycomb-repressed genes to polycomb bodies. PLoS Genet (2013) 1.03
Enhancer blocking and transvection at the Drosophila apterous locus. Genetics (2008) 0.99
Integrity of the Mod(mdg4)-67.2 BTB domain is critical to insulator function in Drosophila melanogaster. Mol Cell Biol (2006) 0.98
Enrichment of HP1a on Drosophila chromosome 4 genes creates an alternate chromatin structure critical for regulation in this heterochromatic domain. PLoS Genet (2012) 0.97
Extensive conservation of sequences and chromatin structures in the bxd polycomb response element among Drosophilid species. Int J Dev Biol (2002) 0.92
The ThioredoxinT and deadhead gene pair encode testis- and ovary-specific thioredoxins in Drosophila melanogaster. Chromosoma (2003) 0.91
Regulation of Polycomb group genes Psc and Su(z)2 in Drosophila melanogaster. Mech Dev (2012) 0.84
Intercalary heterochromatin in Drosophila melanogaster polytene chromosomes and the problem of genetic silencing. Genetica (2003) 0.82
A little bit of sugar makes polycomb better. J Mol Cell Biol (2009) 0.78
Differentiation and gene regulation. Genomic programs and differentiation: editorial overview. Curr Opin Genet Dev (2006) 0.76
Binding the boundaries of chromatin domains. Genome Biol (2014) 0.75
Corrigendum to "Regulation of Polycomb group genes Psc and Su(z)2 in Drosophila melanogaster" [Mech. Dev. 128 (2012) 536-547]. Mech Dev (2017) 0.75