Published in Hum Mol Genet on April 28, 2008
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The chromosome 9p21.3 coronary heart disease risk allele is associated with altered gene expression in normal heart and vascular tissues. PLoS One (2012) 0.91
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The relationship between polymorphisms on chromosome 9p21 and age of onset of coronary heart disease in black and white women. Genet Test Mol Biomarkers (2011) 0.85
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Smoking modifies the associated increased risk of future cardiovascular disease by genetic variation on chromosome 9p21. PLoS One (2014) 0.82
Validated context-dependent associations of coronary heart disease risk with genotype variation in the chromosome 9p21 region: the Atherosclerosis Risk in Communities study. Hum Genet (2014) 0.82
Interaction of type 2 diabetes mellitus with chromosome 9p21 rs10757274 polymorphism on the risk of myocardial infarction: a case-control study in Chinese population. BMC Cardiovasc Disord (2014) 0.81
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The association between variants on chromosome 9p21 and inflammatory biomarkers in ethnically diverse women with coronary heart disease: a pilot study. Biol Res Nurs (2011) 0.79
Susceptibility Loci for Clinical Coronary Artery Disease and Subclinical Coronary Atherosclerosis Throughout the Life-Course. Circ Cardiovasc Genet (2015) 0.78
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The Chromosome 9p21 CVD- and T2D-Associated Regions in a Norwegian Population (The HUNT2 Survey). Int J Endocrinol (2015) 0.76
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The 9p21 locus is associated with coronary artery disease and cardiovascular events in the presence (but not in the absence) of coronary calcification. PLoS One (2014) 0.75
Polymorphism on Chromosome 9p21.3 Is Associated with Severity and Early-Onset CAD in Type 2 Diabetic Tunisian Population. Dis Markers (2015) 0.75
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Variants in ANRIL gene correlated with its expression contribute to myocardial infarction risk. Oncotarget (2017) 0.75
Genes, diabetes and cardiovascular risk prediction. Nat Rev Endocrinol (2009) 0.75
The Trp719Arg polymorphism of the KIF6 gene and coronary heart disease risk: systematic review and meta-analysis. Hereditas (2015) 0.75
Maternal family history of diabetes is associated with a reduced risk of cardiovascular disease in women with type 2 diabetes: the Fremantle Diabetes Study. Diabetes Care (2010) 0.75
Finding the culprit: who is turning hearts to stone? Stem Cell Investig (2017) 0.75
The rs10757278 polymorphism of the 9p21.3 locus is associated with premature coronary artery disease in Polish patients. Genet Test Mol Biomarkers (2012) 0.75
The cis and trans effects of the risk variants of coronary artery disease in the Chr9p21 region. BMC Med Genomics (2015) 0.75
Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature (2007) 144.95
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The structure of haplotype blocks in the human genome. Science (2002) 50.88
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Performing the exact test of Hardy-Weinberg proportion for multiple alleles. Biometrics (1992) 21.26
A common allele on chromosome 9 associated with coronary heart disease. Science (2007) 20.37
A common variant on chromosome 9p21 affects the risk of myocardial infarction. Science (2007) 18.96
Genetic Power Calculator: design of linkage and association genetic mapping studies of complex traits. Bioinformatics (2003) 17.92
Replicating genotype-phenotype associations. Nature (2007) 16.11
Testing association of statistically inferred haplotypes with discrete and continuous traits in samples of unrelated individuals. Hum Hered (2002) 8.64
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Model-free analysis and permutation tests for allelic associations. Hum Hered (2000) 3.70
Coronary calcium measurements: effect of CT scanner type and calcium measure on rescan reproducibility--MESA study. Radiology (2005) 3.08
Four SNPs on chromosome 9p21 in a South Korean population implicate a genetic locus that confers high cross-race risk for development of coronary artery disease. Arterioscler Thromb Vasc Biol (2007) 2.38
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Replication of the association between a chromosome 9p21 polymorphism and coronary artery disease in Japanese and Korean populations. J Hum Genet (2008) 1.94
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Metabolic syndrome and early-onset coronary artery disease: is the whole greater than its parts? J Am Coll Cardiol (2006) 1.40
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Screening patients for subclinical atherosclerosis with non-contrast cardiac CT. Atherosclerosis (2007) 0.98
Ethnic differences in coronary artery calcium in a healthy cohort aged 60 to 69 years. Am J Cardiol (2007) 0.96
Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project. Nature (2007) 75.09
Genome-wide mapping of in vivo protein-DNA interactions. Science (2007) 64.92
Model-based analysis of ChIP-Seq (MACS). Genome Biol (2008) 51.63
The diploid genome sequence of an Asian individual. Nature (2008) 46.29
Heart disease and stroke statistics--2012 update: a report from the American Heart Association. Circulation (2011) 31.98
Heart disease and stroke statistics--2013 update: a report from the American Heart Association. Circulation (2012) 30.79
Heart disease and stroke statistics--2011 update: a report from the American Heart Association. Circulation (2010) 30.07
Biological, clinical and population relevance of 95 loci for blood lipids. Nature (2010) 28.21
Heart disease and stroke statistics--2014 update: a report from the American Heart Association. Circulation (2013) 28.02
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. Nat Genet (2010) 23.08
Heart disease and stroke statistics--2015 update: a report from the American Heart Association. Circulation (2014) 22.74
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Hundreds of variants clustered in genomic loci and biological pathways affect human height. Nature (2010) 20.01
Evolving gene/transcript definitions significantly alter the interpretation of GeneChip data. Nucleic Acids Res (2005) 17.58
The sequence and de novo assembly of the giant panda genome. Nature (2009) 15.76
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Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease. Nat Genet (2011) 13.25
Personal omics profiling reveals dynamic molecular and medical phenotypes. Cell (2012) 12.32
A randomized trial of therapies for type 2 diabetes and coronary artery disease. N Engl J Med (2009) 12.15
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The genome of the cucumber, Cucumis sativus L. Nat Genet (2009) 8.19
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Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs. Nat Genet (2013) 8.02
Third universal definition of myocardial infarction. Eur Heart J (2012) 7.98
Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution. Nat Genet (2010) 7.94
An abundance of rare functional variants in 202 drug target genes sequenced in 14,002 people. Science (2012) 7.94
The importance of race and ethnic background in biomedical research and clinical practice. N Engl J Med (2003) 7.94
The Chronic Renal Insufficiency Cohort (CRIC) Study: Design and Methods. J Am Soc Nephrol (2003) 7.79
The Genomes of Oryza sativa: a history of duplications. PLoS Biol (2005) 7.67
Large-scale association analysis identifies new risk loci for coronary artery disease. Nat Genet (2012) 7.59
Body mass index and risk for end-stage renal disease. Ann Intern Med (2006) 7.56
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Validation and refinement of scores to predict very early stroke risk after transient ischaemic attack. Lancet (2007) 7.27
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Depressive symptoms and health-related quality of life: the Heart and Soul Study. JAMA (2003) 7.01
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A draft sequence for the genome of the domesticated silkworm (Bombyx mori). Science (2004) 6.62
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An abundance of bidirectional promoters in the human genome. Genome Res (2004) 5.90
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Adaptive evolution of pelvic reduction in sticklebacks by recurrent deletion of a Pitx1 enhancer. Science (2009) 5.64